#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O00716 uniprotkb:Q9NRZ9 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1056215|uniprotkb:Q3LID1|uniprotkb:Q6I7N7|uniprotkb:Q76H76|uniprotkb:Q76H77|uniprotkb:Q76H78|uniprotkb:Q76H79|uniprotkb:Q76H80|uniprotkb:Q76H81|uniprotkb:Q7Z397|uniprotkb:Q7Z5X2|uniprotkb:Q8N6P4|uniprotkb:Q9H4P5|uniprotkb:B2RB41|ensembl:ENSP00000239027 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:hells_human(display_long)|uniprotkb:HELLS(gene name)|psi-mi:HELLS(display_short)|uniprotkb:SMARCA6(gene name synonym)|uniprotkb:PASG(gene name synonym)|uniprotkb:Nbla10143(orf name)|uniprotkb:SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6(gene name synonym)|uniprotkb:Proliferation-associated SNF2-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7600022|mint:MINT-8376026|imex:IM-20874-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376028(identity) refseq:NP_060533.2|refseq:NP_001275996.1|refseq:NP_001275997.1|refseq:NP_001275998.1|refseq:NP_001275999.1|refseq:NP_001276000.1|refseq:NP_001276001.1|refseq:NP_001276002.1|refseq:NP_001276003.1|refseq:NP_001276004.1|ensembl:ENSG00000119969(gene)|ensembl:ENST00000348459(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001655"(urogenital system development)|go:"GO:0003682"(chromatin binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|interpro:IPR044753|mint:Q9NRZ9|mint:MINT-8376029(identity) - - - comment:homomint|comment:mint|figure legend:f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2014/10/16 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:QhCAini69BkBNF7TwsA0pflATBk9606 intact-crc:91112191C6AF4EBF|rigid:GMq0oz1hqVzw6Q7y1ouiyMDIOms false glutathione s tranferase tag:?-?(MINT-8376086)|binding-associated region:1-219(MINT-8376089) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O00716 uniprotkb:P35251 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-476616|uniprotkb:Q5XKF5|uniprotkb:Q6PKU0|uniprotkb:Q86V41|uniprotkb:Q86V46|ensembl:ENSP00000371321|uniprotkb:A8K6E7 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rfc1_human(display_long)|uniprotkb:Activator 1 subunit 1(gene name synonym)|uniprotkb:Replication factor C large subunit(gene name synonym)|uniprotkb:Replication factor C 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 large subunit(gene name synonym)|uniprotkb:DNA-binding protein PO-GA(gene name synonym)|uniprotkb:RFC1(gene name)|psi-mi:RFC1(display_short)|uniprotkb:RFC140(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001191676.1|refseq:NP_002904.3|ensembl:ENSG00000035928(gene)|ensembl:ENST00000381897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090618"(DNA clamp unloading)|interpro:IPR001357(BRCT)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012178(DNA replication factor C, large subunit)|interpro:IPR013725(DNA replication factor RFC1, C-terminal)|interpro:IPR027417|interpro:IPR036420|mint:P35251|rcsb pdb:2EBU|rcsb pdb:2K6G|rcsb pdb:2K7F|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|mint:MINT-8376244(identity)|uniprotkb:P35251(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:m4MUwhmpn0xCElyHLAw4FlIVyBs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P35251 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-476616|uniprotkb:Q5XKF5|uniprotkb:Q6PKU0|uniprotkb:Q86V41|uniprotkb:Q86V46|ensembl:ENSP00000371321|uniprotkb:A8K6E7 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rfc1_human(display_long)|uniprotkb:Activator 1 subunit 1(gene name synonym)|uniprotkb:Replication factor C large subunit(gene name synonym)|uniprotkb:Replication factor C 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 large subunit(gene name synonym)|uniprotkb:DNA-binding protein PO-GA(gene name synonym)|uniprotkb:RFC1(gene name)|psi-mi:RFC1(display_short)|uniprotkb:RFC140(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001191676.1|refseq:NP_002904.3|ensembl:ENSG00000035928(gene)|ensembl:ENST00000381897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090618"(DNA clamp unloading)|interpro:IPR001357(BRCT)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012178(DNA replication factor C, large subunit)|interpro:IPR013725(DNA replication factor RFC1, C-terminal)|interpro:IPR027417|interpro:IPR036420|mint:P35251|rcsb pdb:2EBU|rcsb pdb:2K6G|rcsb pdb:2K7F|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|mint:MINT-8376312(identity)|uniprotkb:P35251(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:m4MUwhmpn0xCElyHLAw4FlIVyBs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P35251 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-476616|uniprotkb:Q5XKF5|uniprotkb:Q6PKU0|uniprotkb:Q86V41|uniprotkb:Q86V46|ensembl:ENSP00000371321|uniprotkb:A8K6E7 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rfc1_human(display_long)|uniprotkb:Activator 1 subunit 1(gene name synonym)|uniprotkb:Replication factor C large subunit(gene name synonym)|uniprotkb:Replication factor C 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 large subunit(gene name synonym)|uniprotkb:DNA-binding protein PO-GA(gene name synonym)|uniprotkb:RFC1(gene name)|psi-mi:RFC1(display_short)|uniprotkb:RFC140(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001191676.1|refseq:NP_002904.3|ensembl:ENSG00000035928(gene)|ensembl:ENST00000381897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090618"(DNA clamp unloading)|interpro:IPR001357(BRCT)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012178(DNA replication factor C, large subunit)|interpro:IPR013725(DNA replication factor RFC1, C-terminal)|interpro:IPR027417|interpro:IPR036420|mint:P35251|rcsb pdb:2EBU|rcsb pdb:2K6G|rcsb pdb:2K7F|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|mint:MINT-8376360(identity)|uniprotkb:P35251(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:m4MUwhmpn0xCElyHLAw4FlIVyBs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q8IXI2 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1396430|uniprotkb:A4FVB6|uniprotkb:Q6NUR3|uniprotkb:Q6P9F8|uniprotkb:Q6PJG1|uniprotkb:Q6YMW8|uniprotkb:Q86UB0|uniprotkb:Q8IW28|uniprotkb:Q8IXJ7|uniprotkb:Q9H067|uniprotkb:Q9H9N8|uniprotkb:Q9NUZ2|uniprotkb:A6NFV0|uniprotkb:B4DG48|uniprotkb:J9JIH9|ensembl:ENSP00000334724 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:miro1_human(display_long)|uniprotkb:Ras homolog gene family member T1(gene name synonym)|uniprotkb:Rac-GTP-binding protein-like protein(gene name synonym)|uniprotkb:RHOT1(gene name)|psi-mi:RHOT1(display_short)|uniprotkb:ARHT1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001028738.1|refseq:NP_001028740.1|refseq:NP_060777.3|refseq:NP_001028739.2|refseq:NP_001275683.1|refseq:NP_001275684.1|refseq:NP_001275687.1|dip:DIP-39114N|ensembl:ENSG00000126858(gene)|ensembl:ENST00000333942(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034640"(establishment of mitochondrion localization by microtubule attachment)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|interpro:IPR029506|mint:Q8IXI2|rcsb pdb:5KSO|rcsb pdb:5KSP|rcsb pdb:5KSY|rcsb pdb:5KSZ|rcsb pdb:5KTY|rcsb pdb:5KU1|rcsb pdb:6D71|reactome:R-HSA-5689880|reactome:R-HSA-9013425|mint:MINT-8376092(identity)|uniprotkb:Q8IXI2(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:gA6A8bgSwshvMwCO0cG66h+wwIY9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P35251 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-476616|uniprotkb:Q5XKF5|uniprotkb:Q6PKU0|uniprotkb:Q86V41|uniprotkb:Q86V46|ensembl:ENSP00000371321|uniprotkb:A8K6E7 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rfc1_human(display_long)|uniprotkb:Activator 1 subunit 1(gene name synonym)|uniprotkb:Replication factor C large subunit(gene name synonym)|uniprotkb:Replication factor C 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 large subunit(gene name synonym)|uniprotkb:DNA-binding protein PO-GA(gene name synonym)|uniprotkb:RFC1(gene name)|psi-mi:RFC1(display_short)|uniprotkb:RFC140(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001191676.1|refseq:NP_002904.3|ensembl:ENSG00000035928(gene)|ensembl:ENST00000381897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090618"(DNA clamp unloading)|interpro:IPR001357(BRCT)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012178(DNA replication factor C, large subunit)|interpro:IPR013725(DNA replication factor RFC1, C-terminal)|interpro:IPR027417|interpro:IPR036420|mint:P35251|rcsb pdb:2EBU|rcsb pdb:2K6G|rcsb pdb:2K7F|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|mint:MINT-8376400(identity)|uniprotkb:P35251(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:m4MUwhmpn0xCElyHLAw4FlIVyBs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P35251 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-476616|uniprotkb:Q5XKF5|uniprotkb:Q6PKU0|uniprotkb:Q86V41|uniprotkb:Q86V46|ensembl:ENSP00000371321|uniprotkb:A8K6E7 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rfc1_human(display_long)|uniprotkb:Activator 1 subunit 1(gene name synonym)|uniprotkb:Replication factor C large subunit(gene name synonym)|uniprotkb:Replication factor C 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 large subunit(gene name synonym)|uniprotkb:DNA-binding protein PO-GA(gene name synonym)|uniprotkb:RFC1(gene name)|psi-mi:RFC1(display_short)|uniprotkb:RFC140(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001191676.1|refseq:NP_002904.3|ensembl:ENSG00000035928(gene)|ensembl:ENST00000381897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090618"(DNA clamp unloading)|interpro:IPR001357(BRCT)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012178(DNA replication factor C, large subunit)|interpro:IPR013725(DNA replication factor RFC1, C-terminal)|interpro:IPR027417|interpro:IPR036420|mint:P35251|rcsb pdb:2EBU|rcsb pdb:2K6G|rcsb pdb:2K7F|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|mint:MINT-8376378(identity)|uniprotkb:P35251(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:m4MUwhmpn0xCElyHLAw4FlIVyBs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q8IXI1 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1396563|uniprotkb:Q8NF53|uniprotkb:Q96C13|uniprotkb:Q96S17|uniprotkb:Q9BT60|uniprotkb:Q9H7M8|uniprotkb:A2IDC2|ensembl:ENSP00000321971 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:miro2_human(display_long)|uniprotkb:RHOT2(gene name)|psi-mi:RHOT2(display_short)|uniprotkb:ARHT2(gene name synonym)|uniprotkb:C16orf39(gene name synonym)|uniprotkb:Ras homolog gene family member T2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_620124.1|ensembl:ENSG00000140983(gene)|ensembl:ENST00000315082(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|mint:Q8IXI1|rcsb pdb:5KUT|reactome:R-HSA-9013419|mint:MINT-8376082(identity)|uniprotkb:Q8IXI1(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:E+WoN8aoND+U/YkLBUTecrNbDXg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9Y6V0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-7600273|uniprotkb:A6NNX9|intact:MINT-4542387|uniprotkb:Q9UIV2|uniprotkb:Q9Y6U9|uniprotkb:A4D1A7|uniprotkb:Q08E72|uniprotkb:Q9BVC8|uniprotkb:O60305|uniprotkb:O43373|intact:EBI-28967684|ensembl:ENSP00000334319 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:pclo_human(display_long)|uniprotkb:PCLO(gene name)|psi-mi:PCLO(display_short)|uniprotkb:ACZ(gene name synonym)|uniprotkb:KIAA0559(gene name synonym)|uniprotkb:Aczonin(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSP00000334319|ensembl:ENST00000423517|ensembl:ENSP00000388393|ensembl:ENST00000618073|ensembl:ENSP00000482390|refseq:NP_055325.2|refseq:NP_149015.2|ensembl:ENSG00000186472(gene)|ensembl:ENST00000333891(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030424"(axon)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0045202"(synapse)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR030629|interpro:IPR035892|interpro:IPR036034|interpro:IPR042720|rcsb pdb:1UJD|reactome:R-HSA-9662360|mint:MINT-8376298(identity)|uniprotkb:Q9Y6V0(original identifier) go:"GO:0005634"(nucleus) - function:May act as a scaffolding protein involved in the organization of synaptic active zones and in synaptic vesicle trafficking|comment:mint|comment:homomint figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:V3ei7kBzjfwwNZUYH7eaIQ7tZIM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q6P9B9 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-7600112|intact:MINT-4539005|uniprotkb:Q9C0G5|uniprotkb:Q8N6W5|ensembl:ENSP00000327889 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:int5_human(display_long)|uniprotkb:INTS5(gene name)|psi-mi:INTS5(display_short)|uniprotkb:KIAA1698(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_085131.1|ensembl:ENSG00000185085(gene)|ensembl:ENST00000330574(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016180"(snRNA processing)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR029444|interpro:IPR029445|interpro:IPR040316|rcsb pdb:7CUN|reactome:R-HSA-6807505|mint:MINT-8376268(identity)|uniprotkb:Q6P9B9(original identifier) go:"GO:0005634"(nucleus) - function:"Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes"|comment:mint|comment:homomint figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:2pirjs+e6eyNQayJnDp3NCjUhCk9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q8IZF2 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-7600130|uniprotkb:Q86SP0|intact:MINT-4715450|uniprotkb:Q9Y3Z2|uniprotkb:Q6RGN2|uniprotkb:O94858|uniprotkb:Q5TF06|ensembl:ENSP00000265417|ensembl:ENSP00000283296 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:agrf5_human(display_long)|uniprotkb:ADGRF5(gene name)|psi-mi:ADGRF5(display_short)|uniprotkb:G-protein coupled receptor 116(gene name synonym)|uniprotkb:GPR116(gene name synonym)|uniprotkb:KIAA0758(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001091988.1|refseq:NP_056049.4|ensembl:ENSG00000069122(gene)|ensembl:ENST00000265417(transcript)|ensembl:ENST00000283296(transcript)|go:"GO:0003094"(glomerular filtration)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0045177"(apical part of cell)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0048821"(erythrocyte development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|interpro:IPR000082(SEA)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008078(GPCR, family 2, Ig-hepta receptor)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017981|interpro:IPR017983|interpro:IPR036179|interpro:IPR036364|reactome:R-HSA-5683826|mint:MINT-8376120(identity)|uniprotkb:Q8IZF2(original identifier) go:"GO:0005634"(nucleus) - function:May have a role in the regulation of acid-base balance|comment:mint|comment:homomint figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:JWwE03nAJjMKRlmk9JVr17+4W0U9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9HCL2 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-7600236|intact:UNK-5860628|uniprotkb:Q5VW51|uniprotkb:Q86TA3|ensembl:ENSP00000265276 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:gpat1_human(display_long)|uniprotkb:GPAM(gene name)|psi-mi:GPAM(display_short)|uniprotkb:KIAA1560(gene name synonym)|uniprotkb:GPAT1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001231878.1|refseq:NP_065969.3|ensembl:ENSG00000119927(gene)|ensembl:ENST00000348367(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0004366"(glycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006655"(phosphatidylglycerol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0009749"(response to glucose)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0051607"(defense response to virus)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0102420"("sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity")|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR022284|interpro:IPR028354|interpro:IPR041728|reactome:R-HSA-1483166|reactome:R-HSA-2426168|reactome:R-HSA-75109|reactome:R-HSA-8931987|reactome:R-HSA-9018519|refseq:XP_005270055.1|mint:MINT-8376162(identity)|uniprotkb:Q9HCL2(original identifier) go:"GO:0005634"(nucleus) - comment:mint|comment:homomint figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:hq9ndEtE+IMdG04eyblr2+cEBvo9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P43304 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-7600203|uniprotkb:Q59FR1|intact:MINT-4530883|uniprotkb:Q9HAP9|uniprotkb:A8K4V0|uniprotkb:B3KSA9|ensembl:ENSP00000308610|ensembl:ENSP00000386425|ensembl:ENSP00000386626|ensembl:ENSP00000409708 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:gpdm_human(display_long)|uniprotkb:GPD2(gene name)|psi-mi:GPD2(display_short)|uniprotkb:mtGPD(gene name synonym)|uniprotkb:mitohondrial glycerophosphate dehydrogenase gene(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_016859319.1|refseq:XP_011509279.1|refseq:NP_001076581.2|refseq:NP_000399.3|refseq:XP_005246526.1|ensembl:ENSG00000115159(gene)|ensembl:ENST00000310454(transcript)|ensembl:ENST00000409674(transcript)|ensembl:ENST00000409861(transcript)|ensembl:ENST00000438166(transcript)|go:"GO:0004368"("glycerol-3-phosphate dehydrogenase (quinone) activity")|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006127"(glycerophosphate shuttle)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0052591"("sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity")|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR031656|interpro:IPR036188|interpro:IPR038299|reactome:R-HSA-1483166|reactome:R-HSA-163560|mint:MINT-8376072(identity)|uniprotkb:P43304(original identifier) go:"GO:0005634"(nucleus) - comment:mint|comment:homomint figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:PsG9Eo7dfk8l+vDJl6d4WfEST849606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:O15427 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-7600166|uniprotkb:Q2M1P8|intact:MINT-4526381|uniprotkb:B3KXG8|ensembl:ENSP00000376150|ensembl:ENSP00000376152|ensembl:ENSP00000462405|ensembl:ENSP00000463978|ensembl:ENSP00000464112|ensembl:ENSP00000464625|ensembl:ENSP00000482013|ensembl:ENSP00000483212 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mot4_human(display_long)|uniprotkb:SLC16A3(gene name)|psi-mi:SLC16A3(display_short)|uniprotkb:MCT4(gene name synonym)|uniprotkb:Solute carrier family 16 member 3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_011521909.1|refseq:NP_001193879.1|refseq:NP_001193880.1|refseq:NP_001035888.1|refseq:NP_004198.1|refseq:NP_001035887.1|refseq:NP_001193881.1|ensembl:ENSG00000141526(gene)|ensembl:ENST00000392339(transcript)|ensembl:ENST00000392341(transcript)|ensembl:ENST00000580189(transcript)|ensembl:ENST00000581287(transcript)|ensembl:ENST00000582743(transcript)|ensembl:ENST00000584689(transcript)|ensembl:ENST00000617373(transcript)|ensembl:ENST00000619321(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR030756|interpro:IPR036259|mint:O15427|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-70268|mint:MINT-8376574(identity)|uniprotkb:O15427(original identifier) go:"GO:0005634"(nucleus) - comment:mint|function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate|comment:homomint figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:Ipq+K2KMGnogWD9ouLcBjZ53ICs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q14739 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N|mint:MINT-8376548(identity)|uniprotkb:Q14739(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9NQB0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430|mint:MINT-8376084(identity)|uniprotkb:Q9NQB0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:497W27pxWi8NOaZCdsthvR8mKxU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q7Z460 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-913476|uniprotkb:B7ZLX3|uniprotkb:O75118|uniprotkb:Q2KHQ9|uniprotkb:Q5H9P0|uniprotkb:Q8N5B8|uniprotkb:Q9BQT5|ensembl:ENSP00000263710|intact:EBI-2562829|uniprotkb:A2RU21|uniprotkb:F5GWS0|intact:EBI-10967465 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:clap1_human(display_long)|uniprotkb:CLASP1(gene name)|psi-mi:CLASP1(display_short)|uniprotkb:KIAA0622(gene name synonym)|uniprotkb:MAST1(gene name synonym)|uniprotkb:Cytoplasmic linker-associated protein 1(gene name synonym)|uniprotkb:Multiple asters homolog 1(gene name synonym)|uniprotkb:Protein Orbit homolog 1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001135745.1|refseq:NP_001135746.1|refseq:NP_001193980.1|refseq:NP_056097.1|ensembl:ENSG00000074054(gene)|ensembl:ENST00000263710(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0016020"(membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031592"(centrosomal corona)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045180"(basal cortex)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:XP_011509150.1|ensembl:ENSP00000263710|ensembl:ENST00000397587|ensembl:ENSP00000380717|ensembl:ENST00000409078|ensembl:ENSP00000386442|ensembl:ENST00000541377|ensembl:ENSP00000441625|interpro:IPR024395|interpro:IPR028399|interpro:IPR034085|rcsb pdb:4K92|rcsb pdb:6MQ5|rcsb pdb:6MQ7|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-428890|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|mint:MINT-8376070(identity)|uniprotkb:Q7Z460(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ZhVWdhW2ylZHeewHZ63lg5FQT1c9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q03701 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1046778|uniprotkb:Q8NE75|ensembl:ENSP00000234170 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:cebpz_human(display_long)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:CEBPZ(gene name)|psi-mi:CEBPZ(display_short)|uniprotkb:CBF2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_005751.2|ensembl:ENSG00000115816(gene)|ensembl:ENST00000234170(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|mint:Q03701|mint:MINT-8376352(identity)|uniprotkb:Q03701(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:4VX4KR6JGLaEMorRYbfPRaMgGuE9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q92830 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-477622|uniprotkb:Q9UCW1|uniprotkb:Q8N1A2|ensembl:ENSP00000225916 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:kat2a_human(display_long)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:STAF97(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:GCN5L2(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:KAT2A(gene name)|psi-mi:KAT2A(display_short)|uniprotkb:GCN5(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_066564.2|ensembl:ENSG00000108773(gene)|ensembl:ENST00000225916(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q92830|rcsb pdb:1F68|rcsb pdb:1Z4R|rcsb pdb:3D7C|rcsb pdb:5H84|rcsb pdb:5H86|rcsb pdb:5MLJ|rcsb pdb:5TRL|rcsb pdb:5TRM|rcsb pdb:6J3P|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5689880|reactome:R-HSA-73762|reactome:R-HSA-8941856|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|reactome:R-HSA-9013508|reactome:R-HSA-9013695|refseq:XP_016879937.1|dip:DIP-28146N|mint:MINT-8376214(identity)|uniprotkb:Q92830(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:PwDTlmU+caK91Xbiv7xm4xejZok9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376382(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9H6R0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2512405|ensembl:ENSP00000225296|uniprotkb:Q4G149|uniprotkb:B4DHF9|uniprotkb:Q5CZ73|uniprotkb:Q9H5M9 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:dhx33_human(display_long)|uniprotkb:DHX33(gene name)|psi-mi:DHX33(display_short)|uniprotkb:DDX33(gene name synonym)|uniprotkb:DEAH box protein 33(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000005100(gene)|ensembl:ENST00000225296(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q9H6R0|refseq:NP_001186628.1|refseq:NP_064547.2|refseq:XP_016880366.1|mint:MINT-8376096(identity)|uniprotkb:Q9H6R0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:jR/BdCPb1fZgJxOWaxNRfqo0AvQ9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P51153 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1780121|uniprotkb:Q5U0A6|uniprotkb:Q6GPG6|uniprotkb:Q96GU4|uniprotkb:A8K6B5|uniprotkb:D3DV67|ensembl:ENSP00000357564 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rab13_human(display_long)|uniprotkb:RAB13(gene name)|psi-mi:RAB13(display_short)|uniprotkb:GIG4(orf name)|uniprotkb:Cell growth-inhibiting gene 4 protein(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_002861.1|refseq:NP_001258967.1|dip:DIP-40268N|ensembl:ENSG00000143545(gene)|ensembl:ENST00000368575(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0044795"(trans-Golgi network to recycling endosome transport)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097368"(establishment of Sertoli cell barrier)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51153|reactome:R-HSA-1445148|reactome:R-HSA-8873719|reactome:R-HSA-8876198|mint:MINT-8376562(identity)|uniprotkb:P51153(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:XopTW/3AqUPyTi66Nf0HYlkD6Fw9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P16615 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N|mint:MINT-8376288(identity)|uniprotkb:P16615(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q00325 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|mint:MINT-8376066(identity)|uniprotkb:Q00325(original identifier) go:"GO:0005634"(nucleus) - crc64:78714C85931B22D5 figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9Y3T9 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756|mint:MINT-8376150(identity)|uniprotkb:Q9Y3T9(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9NZ01 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1|mint:MINT-8376538(identity)|uniprotkb:Q9NZ01(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q96JM7 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|mint:MINT-8376200(identity)|uniprotkb:Q96JM7(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q00325 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|mint:MINT-8376536(identity)|uniprotkb:Q00325(original identifier) go:"GO:0005634"(nucleus) - crc64:78714C85931B22D5 figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q96RE9 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2826684|uniprotkb:B3KU35|uniprotkb:Q17RP3|uniprotkb:Q5H9N5|uniprotkb:A8MY91|uniprotkb:B4DU78|uniprotkb:Q06DQ3|ensembl:ENSP00000274599|uniprotkb:F5GWS1 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:zn300_human(display_long)|uniprotkb:ZNF300(gene name)|psi-mi:ZNF300(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001166302.1|refseq:NP_001166303.1|refseq:NP_443092.1|ensembl:ENSG00000145908(gene)|ensembl:ENST00000274599(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|mint:MINT-8376472(identity)|uniprotkb:Q96RE9(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:38iNcXE1eJW5dyX9zAN46FoXT589606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q92830 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-477622|uniprotkb:Q9UCW1|uniprotkb:Q8N1A2|ensembl:ENSP00000225916 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:kat2a_human(display_long)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:STAF97(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:GCN5L2(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:KAT2A(gene name)|psi-mi:KAT2A(display_short)|uniprotkb:GCN5(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_066564.2|ensembl:ENSG00000108773(gene)|ensembl:ENST00000225916(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q92830|rcsb pdb:1F68|rcsb pdb:1Z4R|rcsb pdb:3D7C|rcsb pdb:5H84|rcsb pdb:5H86|rcsb pdb:5MLJ|rcsb pdb:5TRL|rcsb pdb:5TRM|rcsb pdb:6J3P|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5689880|reactome:R-HSA-73762|reactome:R-HSA-8941856|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|reactome:R-HSA-9013508|reactome:R-HSA-9013695|refseq:XP_016879937.1|dip:DIP-28146N|mint:MINT-8376174(identity)|uniprotkb:Q92830(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:PwDTlmU+caK91Xbiv7xm4xejZok9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376292(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:O75152 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-748480|uniprotkb:Q6AHY4|uniprotkb:Q6AHY9|uniprotkb:Q6AW79|uniprotkb:Q6AWA1|uniprotkb:Q6PJK4|uniprotkb:Q86XZ7|ensembl:ENSP00000333253|ensembl:ENSP00000356179|ensembl:ENSP00000356181|ensembl:ENSP00000356183|ensembl:ENSP00000491830 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:zc11a_human(display_long)|uniprotkb:ZC3H11A(gene name)|psi-mi:ZC3H11A(display_short)|uniprotkb:KIAA0663(gene name synonym)|uniprotkb:ZC3HDC11A(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_006711736.1|refseq:NP_055642.3|refseq:XP_011508501.1|refseq:XP_011508502.1|refseq:XP_011508503.1|refseq:XP_011508504.1|refseq:NP_001306167.1|refseq:NP_001306168.1|refseq:XP_005245700.1|refseq:XP_005245701.1|refseq:XP_016858445.1|refseq:XP_016858446.1|refseq:XP_016858447.1|refseq:XP_016858448.1|ensembl:ENSG00000058673(gene)|ensembl:ENST00000332127(transcript)|ensembl:ENST00000367210(transcript)|ensembl:ENST00000367212(transcript)|ensembl:ENST00000367214(transcript)|ensembl:ENST00000639812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR041686|mint:O75152|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|mint:MINT-8376254(identity)|uniprotkb:O75152(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:BJfX/K7kBXQGQx6l+Y2xBtwyJAw9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P52948 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|mint:MINT-8376188(identity)|uniprotkb:P52948(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9BQG0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924|mint:MINT-8376310(identity)|uniprotkb:Q9BQG0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P13010 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|mint:MINT-8376074(identity)|uniprotkb:P13010(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P23396 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N|mint:MINT-8376556(identity)|uniprotkb:P23396(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q00325 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|mint:MINT-8376308(identity)|uniprotkb:Q00325(original identifier) go:"GO:0005634"(nucleus) - crc64:78714C85931B22D5 figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P61619 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358919|uniprotkb:Q5JPF8|uniprotkb:P38378|uniprotkb:P57726|uniprotkb:Q8N3U3|uniprotkb:Q8NC71|uniprotkb:Q9BU16|uniprotkb:Q9Y2R3|uniprotkb:Q8N0Z4|ensembl:ENSP00000243253 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:s61a1_human(display_long)|uniprotkb:SEC61A1(gene name)|psi-mi:SEC61A1(display_short)|uniprotkb:SEC61A(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_037468.1|ensembl:ENSG00000058262(gene)|ensembl:ENST00000243253(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0039019"(pronephric nephron development)|go:"GO:0043022"(ribosome binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|mint:P61619|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339|mint:MINT-8376560(identity)|uniprotkb:P61619(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:C+EzS02H/FYMX2nyfksXpRMs8G09606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9NUQ2 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-6916385|ensembl:ENSP00000285518|ensembl:ENSP00000495562|uniprotkb:Q8IZ47|uniprotkb:Q9BQG4 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:plce_human(display_long)|uniprotkb:AGPAT5(gene name)|psi-mi:AGPAT5(display_short)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 5(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase epsilon(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000155189(gene)|ensembl:ENSG00000284980(gene)|ensembl:ENST00000285518(transcript)|ensembl:ENST00000646327(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006639"(acylglycerol metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0016746"(acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR032098|reactome:R-HSA-1483166|refseq:NP_060831.2|mint:MINT-8376558(identity)|uniprotkb:Q9NUQ2(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:Osmz6W9W0rS+khEYpiVNvL14S/I9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UM54 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-350606|uniprotkb:Q5TEM5|uniprotkb:Q5TEM6|uniprotkb:Q5TEM7|uniprotkb:Q9BZZ7|uniprotkb:Q9UEG2|uniprotkb:A6H8V4|uniprotkb:E1P540 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:myo6_human(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:KIAA0389(gene name synonym)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) go:"GO:0051046"(regulation of secretion)|refseq:NP_004990.3|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2N0Z|rcsb pdb:2N10|rcsb pdb:2N11|go:"GO:0060001"(minus-end directed microfilament motor activity)|rcsb pdb:2N12|rcsb pdb:2N13|rcsb pdb:6E5N|rcsb pdb:6J56|reactome:R-HSA-190873|reactome:R-HSA-399719|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|refseq:NP_001287828.1|mint:Q9UM54|dip:DIP-33123N|mint:MINT-8376380(identity)|uniprotkb:Q9UM54(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:LYtnU7aRzVE/LDFhZgcK5IvahC09606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376364(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q92621 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N|mint:MINT-8376272(identity)|uniprotkb:Q92621(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q68E01 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2680854|uniprotkb:Q8TB23|uniprotkb:Q6MZQ4|uniprotkb:Q9H6S9|uniprotkb:Q6AI57|uniprotkb:Q5VUQ6|uniprotkb:Q4G0E5|uniprotkb:B4DQC8|uniprotkb:B4E3U9|uniprotkb:A8K1W0|uniprotkb:Q8NC46|uniprotkb:Q68DJ1|uniprotkb:Q6DKG7|uniprotkb:Q5VUR1|uniprotkb:Q6MZZ9|uniprotkb:Q5VUQ5|uniprotkb:Q69YR5|uniprotkb:Q5VUR0|uniprotkb:D3DV57 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:int3_human(display_long)|uniprotkb:INTS3(gene name)|psi-mi:INTS3(display_short)|uniprotkb:C1orf193(gene name synonym)|uniprotkb:C1orf60(gene name synonym)|uniprotkb:SOSS complex subunit A(gene name synonym)|uniprotkb:Sensor of single-strand DNA complex subunit A(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_075391.3|interpro:IPR019333|refseq:XP_005245518.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0070876"(SOSS complex)|rcsb pdb:4OWT|rcsb pdb:4OWW|rcsb pdb:4OWX|rcsb pdb:6WLG|reactome:R-HSA-6807505|refseq:NP_001311404.1|mint:Q68E01|mint:MINT-8376294(identity)|uniprotkb:Q68E01(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:GxQTTVSOwBdWifr7ZdM8Zbqxy5M9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376232(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q14980 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875|mint:MINT-8376494(identity)|uniprotkb:Q14980(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:O14776 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-473271|uniprotkb:Q2NKN2|uniprotkb:Q59EA1|ensembl:ENSP00000296702 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:tcrg1_human(display_long)|uniprotkb:TATA box-binding protein-associated factor 2S(gene name synonym)|uniprotkb:Transcription factor CA150(gene name synonym)|uniprotkb:TCERG1(gene name)|psi-mi:TCERG1(display_short)|uniprotkb:CA150(gene name synonym)|uniprotkb:TAF2S(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001035095.1|refseq:NP_006697.2|dip:DIP-32504N|ensembl:ENSG00000113649(gene)|ensembl:ENST00000296702(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003711"(transcription elongation regulator activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002713(FF)|interpro:IPR036020|interpro:IPR036517|mint:O14776|rcsb pdb:2DK7|rcsb pdb:2DOD|rcsb pdb:2DOE|rcsb pdb:2DOF|rcsb pdb:2E71|rcsb pdb:2KIQ|rcsb pdb:2KIS|rcsb pdb:2MW9|rcsb pdb:2MWA|rcsb pdb:2MWB|rcsb pdb:2MWD|rcsb pdb:2MWE|rcsb pdb:2MWF|rcsb pdb:2N4R|rcsb pdb:2N4S|rcsb pdb:2N4T|rcsb pdb:2N4U|rcsb pdb:2N4V|rcsb pdb:2N4W|rcsb pdb:2NNT|rcsb pdb:3HFH|rcsb pdb:3Q1I|rcsb pdb:4FQG|rcsb pdb:7ABF|rcsb pdb:7ABG|mint:MINT-8376398(identity)|uniprotkb:O14776(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:KDFTOtTUWHzQ9yzRj7BbhFTQXiM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P13010 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|mint:MINT-8376124(identity)|uniprotkb:P13010(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P16615 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N|mint:MINT-8376236(identity)|uniprotkb:P16615(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:O00767 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2684237|uniprotkb:Q5W037|uniprotkb:B2R5U0|uniprotkb:Q96KF6|uniprotkb:Q53GR9|uniprotkb:Q9Y695|uniprotkb:Q9BS07|uniprotkb:Q16150|uniprotkb:Q6GSS4|uniprotkb:Q5W038|uniprotkb:D3DR68|ensembl:ENSP00000359380 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:scd_human(display_long)|uniprotkb:"Delta(9)-desaturase"(gene name synonym)|uniprotkb:Fatty acid desaturase(gene name synonym)|uniprotkb:Acyl-CoA desaturase(gene name synonym)|uniprotkb:FADS5(gene name synonym)|uniprotkb:SCD1(gene name synonym)|uniprotkb:SCDOS(gene name synonym)|uniprotkb:SCD(gene name)|psi-mi:SCD(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_005054.3|ensembl:ENSG00000099194(gene)|ensembl:ENST00000370355(transcript)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032896"(palmitoyl-CoA 9-desaturase activity)|go:"GO:0070542"(response to fatty acid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903966"(monounsaturated fatty acid biosynthetic process)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|rcsb pdb:4ZYO|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|mint:MINT-8376552(identity)|uniprotkb:O00767(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:GeF7PMgZb07js39m6ykSSmFuIUA9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UM54 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-350606|uniprotkb:Q5TEM5|uniprotkb:Q5TEM6|uniprotkb:Q5TEM7|uniprotkb:Q9BZZ7|uniprotkb:Q9UEG2|uniprotkb:A6H8V4|uniprotkb:E1P540 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:myo6_human(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:KIAA0389(gene name synonym)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) go:"GO:0051046"(regulation of secretion)|refseq:NP_004990.3|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2N0Z|rcsb pdb:2N10|rcsb pdb:2N11|go:"GO:0060001"(minus-end directed microfilament motor activity)|rcsb pdb:2N12|rcsb pdb:2N13|rcsb pdb:6E5N|rcsb pdb:6J56|reactome:R-HSA-190873|reactome:R-HSA-399719|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|refseq:NP_001287828.1|mint:Q9UM54|dip:DIP-33123N|mint:MINT-8376302(identity)|uniprotkb:Q9UM54(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:LYtnU7aRzVE/LDFhZgcK5IvahC09606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376424(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9BQG0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924|mint:MINT-8376438(identity)|uniprotkb:Q9BQG0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P68104 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1|mint:MINT-8376514(identity)|uniprotkb:P68104(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P35222 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1|mint:MINT-8376190(identity)|uniprotkb:P35222(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P52701 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N|mint:MINT-8376416(identity)|uniprotkb:P52701(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P16615 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N|mint:MINT-8376264(identity)|uniprotkb:P16615(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q14980 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875|mint:MINT-8376462(identity)|uniprotkb:Q14980(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P13010 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|mint:MINT-8376132(identity)|uniprotkb:P13010(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P35222 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1|mint:MINT-8376160(identity)|uniprotkb:P35222(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9BQC6 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1055359|uniprotkb:A2A332|ensembl:ENSP00000310726 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rt63_human(display_long)|uniprotkb:MRPL57(gene name)|psi-mi:MRPL57(display_short)|uniprotkb:MRP63(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein 63(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein L57(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL63(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_076931.1|ensembl:ENSG00000173141(gene)|ensembl:ENST00000309594(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR016576(Mitochondrial ribosomal protein 63)|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_016876229.1|mint:MINT-8376114(identity)|uniprotkb:Q9BQC6(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:RErvYq/pbOr8ZZWW9+dJr4eVknQ9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P02545 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N|mint:MINT-8376048(identity)|uniprotkb:P02545(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376446(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UM54 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-350606|uniprotkb:Q5TEM5|uniprotkb:Q5TEM6|uniprotkb:Q5TEM7|uniprotkb:Q9BZZ7|uniprotkb:Q9UEG2|uniprotkb:A6H8V4|uniprotkb:E1P540 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:myo6_human(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:KIAA0389(gene name synonym)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) go:"GO:0051046"(regulation of secretion)|refseq:NP_004990.3|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2N0Z|rcsb pdb:2N10|rcsb pdb:2N11|go:"GO:0060001"(minus-end directed microfilament motor activity)|rcsb pdb:2N12|rcsb pdb:2N13|rcsb pdb:6E5N|rcsb pdb:6J56|reactome:R-HSA-190873|reactome:R-HSA-399719|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|refseq:NP_001287828.1|mint:Q9UM54|dip:DIP-33123N|mint:MINT-8376330(identity)|uniprotkb:Q9UM54(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:LYtnU7aRzVE/LDFhZgcK5IvahC09606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q96JM7 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|mint:MINT-8376170(identity)|uniprotkb:Q96JM7(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9BPX3 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N|mint:MINT-8376442(identity)|uniprotkb:Q9BPX3(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:G45XQBcnTeSunRz57s6lJErxvjo9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q00325 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|mint:MINT-8376458(identity)|uniprotkb:Q00325(original identifier) go:"GO:0005634"(nucleus) - crc64:78714C85931B22D5 figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UQ13 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-993879|uniprotkb:O76063|uniprotkb:A8K9W8|uniprotkb:B3KR23|uniprotkb:Q5VZS8|uniprotkb:Q5VZS9|ensembl:ENSP00000358464 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:shoc2_human(display_long)|uniprotkb:Protein soc-2 homolog(gene name synonym)|uniprotkb:SHOC2(gene name)|psi-mi:SHOC2(display_short)|uniprotkb:KIAA0862(gene name synonym)|uniprotkb:Protein sur-8 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_031399.2|refseq:NP_001311265.1|refseq:NP_001311266.1|refseq:NP_001255968.1|refseq:XP_016872191.1|refseq:XP_016872192.1|refseq:XP_016872193.1|ensembl:ENSG00000108061(gene)|ensembl:ENST00000369452(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027036|interpro:IPR032675|mint:Q9UQ13|reactome:R-HSA-5673000|reactome:R-HSA-9660537|mint:MINT-8376362(identity)|uniprotkb:Q9UQ13(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:0RkCETF3NG59IZjnJevXVYkzBJU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q92621 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N|uniprotkb:Q92621(original identifier)|mint:MINT-8376316(identity) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:O60341 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-710124|uniprotkb:Q5TH94|uniprotkb:Q5TH95|uniprotkb:Q86VT7|uniprotkb:Q8IXK4|uniprotkb:Q8NDP6|uniprotkb:Q8TAZ3|uniprotkb:Q96AW4|ensembl:ENSP00000349049|uniprotkb:A8MWP9 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:kdm1a_human(display_long)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) go:"GO:0021987"(cerebral cortex development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032451"(demethylase activity)|refseq:NP_001009999.1|refseq:NP_055828.2|ensembl:ENSG00000004487(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|ensembl:ENST00000356634(transcript)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-34641N|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0033184"(positive regulation of histone ubiquitination)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046098"(guanine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060992"(response to fungicide)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903827"|go:"GO:1990391"(DNA repair complex)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017366(Histone lysine-specific demethylase)|interpro:IPR036188|interpro:IPR036388|mint:O60341|rcsb pdb:2COM|rcsb pdb:2DW4|rcsb pdb:2EJR|rcsb pdb:2H94|rcsb pdb:2HKO|rcsb pdb:2IW5|rcsb pdb:2L3D|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:2Z3Y|rcsb pdb:2Z5U|rcsb pdb:3ABT|rcsb pdb:3ABU|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4CZZ|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5AFW|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5IT3|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6E1F|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6KGO|rcsb pdb:6KGP|rcsb pdb:6KGQ|rcsb pdb:6KGR|rcsb pdb:6NQM|rcsb pdb:6NQU|rcsb pdb:6NR5|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|rcsb pdb:7E0G|rcsb pdb:7JJL|rcsb pdb:7JJM|rcsb pdb:7JK7|reactome:R-HSA-3214815|reactome:R-HSA-3214842|reactome:R-HSA-5625886|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9679191|reactome:R-HSA-983231|mint:MINT-8376270(identity)|uniprotkb:O60341(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376404(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q08211 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body)|mint:MINT-8376386(identity)|uniprotkb:Q08211(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q16206 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-744159|uniprotkb:Q5VTJ1|uniprotkb:Q5VTJ2|uniprotkb:Q8WUX0|uniprotkb:Q9NTP6|uniprotkb:Q9UH82|intact:EBI-2623308|uniprotkb:A8K197|uniprotkb:A8K1C2|ensembl:ENSP00000337146|ensembl:ENSP00000359965 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:enox2_human(display_long)|uniprotkb:Tumor-associated hydroquinone oxidase(gene name synonym)|uniprotkb:Cytosolic ovarian carcinoma antigen 1(gene name synonym)|uniprotkb:APK1 antigen(gene name synonym)|uniprotkb:ENOX2(gene name)|psi-mi:ENOX2(display_short)|uniprotkb:COVA1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_006366.2|refseq:NP_872114.1|refseq:XP_011529549.1|refseq:XP_011529551.1|refseq:XP_011529553.1|refseq:NP_001268665.1|refseq:XP_005262411.1|mint:Q16206|interpro:IPR038876|ensembl:ENST00000338144(transcript)|ensembl:ENST00000370927(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007624"(ultradian rhythm)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0022900"(electron transport chain)|go:"GO:0040008"(regulation of growth)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034140|interpro:IPR035979|ensembl:ENSG00000165675(gene)|refseq:XP_016884715.1|refseq:XP_016884716.1|refseq:XP_016884717.1|mint:MINT-8376068(identity)|uniprotkb:Q16206(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:nqvZJv5GYe49nv+r4Bda6aRZ/mU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9Y3T9 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756|mint:MINT-8376208(identity)|uniprotkb:Q9Y3T9(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376410(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9H0A0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-876527|ensembl:ENSP00000257829|uniprotkb:B4DFD5|uniprotkb:E7ESU4|uniprotkb:E9PMN9|uniprotkb:Q86WK5|uniprotkb:Q9C0F4|uniprotkb:Q9HA61|uniprotkb:Q9NVF2 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nat10_human(display_long)|uniprotkb:NAT10(gene name)|psi-mi:NAT10(display_short)|uniprotkb:KIAA1709(gene name synonym)|uniprotkb:ALP(gene name synonym)|uniprotkb:18S rRNA cytosine acetyltransferase(gene name synonym)|uniprotkb:N-acetyltransferase 10(gene name synonym)|uniprotkb:N-acetyltransferase-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000135372(gene)|ensembl:ENST00000257829(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000154"(rRNA modification)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051391"(tRNA acetylation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0106162"(mRNA N-acetyltransferase activity)|go:"GO:1904812"(rRNA acetylation involved in maturation of SSU-rRNA)|go:"GO:1990883"(rRNA cytidine N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR007807(Protein of unknown function DUF699, ATPase putative)|interpro:IPR013562(Region of unknown function DUF1726)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR027992|interpro:IPR032672|interpro:IPR033688|mint:Q9H0A0|rcsb pdb:6VLA|reactome:R-HSA-6790901|refseq:NP_001137502.1|refseq:NP_078938.2|mint:MINT-8376282(identity)|uniprotkb:Q9H0A0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:3eWpscghkRC8Km7mBsUQqjhCKVs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:O00767 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2684237|uniprotkb:Q5W037|uniprotkb:B2R5U0|uniprotkb:Q96KF6|uniprotkb:Q53GR9|uniprotkb:Q9Y695|uniprotkb:Q9BS07|uniprotkb:Q16150|uniprotkb:Q6GSS4|uniprotkb:Q5W038|uniprotkb:D3DR68|ensembl:ENSP00000359380 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:scd_human(display_long)|uniprotkb:"Delta(9)-desaturase"(gene name synonym)|uniprotkb:Fatty acid desaturase(gene name synonym)|uniprotkb:Acyl-CoA desaturase(gene name synonym)|uniprotkb:FADS5(gene name synonym)|uniprotkb:SCD1(gene name synonym)|uniprotkb:SCDOS(gene name synonym)|uniprotkb:SCD(gene name)|psi-mi:SCD(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_005054.3|ensembl:ENSG00000099194(gene)|ensembl:ENST00000370355(transcript)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032896"(palmitoyl-CoA 9-desaturase activity)|go:"GO:0070542"(response to fatty acid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903966"(monounsaturated fatty acid biosynthetic process)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|rcsb pdb:4ZYO|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|mint:MINT-8376488(identity)|uniprotkb:O00767(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:GeF7PMgZb07js39m6ykSSmFuIUA9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P13010 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|mint:MINT-8376046(identity)|uniprotkb:P13010(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P06400 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N|mint:MINT-8376266(identity)|uniprotkb:P06400(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:xidCNX96KlQzu160polvT61k4Zw9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P68104 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1|mint:MINT-8376554(identity)|uniprotkb:P68104(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P35221 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467|mint:MINT-8376242(identity)|uniprotkb:P35221(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P19338 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226|mint:MINT-8376226(identity)|uniprotkb:P19338(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P40939 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|mint:MINT-8376064(identity)|uniprotkb:P40939(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376388(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q92871 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-746784|uniprotkb:Q92586|ensembl:ENSP00000216259|uniprotkb:A8K003 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:pmm1_human(display_long)|uniprotkb:PMMH-22(gene name synonym)|uniprotkb:PMM1(gene name)|psi-mi:PMM1(display_short)|uniprotkb:PMMH22(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_002667.2|ensembl:ENSG00000100417(gene)|ensembl:ENST00000216259(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR005002(Eukaryotic phosphomannomutase)|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR023214|interpro:IPR036412|interpro:IPR043169|rcsb pdb:2FUC|rcsb pdb:2FUE|rcsb pdb:6CFR|rcsb pdb:6CFS|rcsb pdb:6CFT|rcsb pdb:6CFU|rcsb pdb:6CFV|reactome:R-HSA-446205|mint:MINT-8376104(identity)|uniprotkb:Q92871(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:81dnT3cBTmay4gBImF2JF9oyrr09606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9H1K0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1105310|uniprotkb:Q3KP30|uniprotkb:Q59EY8|uniprotkb:Q8NAQ1|uniprotkb:B4DWY8|uniprotkb:C9J4P5|ensembl:ENSP00000253699|ensembl:ENSP00000422551 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rbns5_human(display_long)|uniprotkb:RBSN(gene name)|psi-mi:RBSN(display_short)|uniprotkb:110 kDa protein(gene name synonym)|uniprotkb:FYVE finger-containing Rab5 effector protein rabenosyn-5(gene name synonym)|uniprotkb:RAB effector RBSN(gene name synonym)|uniprotkb:ZFYVE20(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 20(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_071735.2|refseq:NP_001289307.1|ensembl:ENSG00000131381(gene)|ensembl:ENST00000253699(transcript)|ensembl:ENST00000476527(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR021565|interpro:IPR036531|mint:Q9H1K0|rcsb pdb:1YZM|rcsb pdb:1Z0J|rcsb pdb:1Z0K|reactome:R-HSA-168138|reactome:R-HSA-983231|refseq:XP_005265441.1|refseq:XP_005265442.1|refseq:XP_016862512.1|mint:MINT-8376216(identity)|uniprotkb:Q9H1K0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:fKkis2EhJdqQj04oUTABbwxEI2Y9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P02768 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-714423|ensembl:ENSP00000295897|uniprotkb:Q645G4|uniprotkb:O95574|uniprotkb:P04277|uniprotkb:Q13140|uniprotkb:Q68DN5|uniprotkb:Q6UXK4|uniprotkb:Q86YG0|uniprotkb:Q9P157|uniprotkb:Q9P1I7|uniprotkb:Q9UHS3|uniprotkb:Q9UJZ0|intact:EBI-7301844|intact:MINT-1161169|uniprotkb:E7ESS9|uniprotkb:Q8IUK7 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:albu_human(display_long)|uniprotkb:GIG42(orf name)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:PRO0903(orf name)|uniprotkb:PRO1708(orf name)|uniprotkb:PRO2044(orf name)|uniprotkb:PRO2619(orf name)|uniprotkb:PRO2675(orf name)|uniprotkb:UNQ696/PRO1341(orf name)|uniprotkb:GIG20(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000163631(gene)|ensembl:ENST00000295897(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:1E78|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051087"(chaperone binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P02768|rcsb pdb:1AO6|rcsb pdb:1BJ5|rcsb pdb:1BKE|rcsb pdb:1BM0|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|rcsb pdb:6XV0|rcsb pdb:6YG9|rcsb pdb:6ZL1|rcsb pdb:7A9C|rcsb pdb:7AAE|rcsb pdb:7AAI|rcsb pdb:7D6J|rcsb pdb:7JWN|reactome:R-HSA-114608|reactome:R-HSA-159418|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2168880|reactome:R-HSA-381426|reactome:R-HSA-879518|reactome:R-HSA-8957275|reactome:R-HSA-8964058|reactome:R-HSA-9707564|rcsb pdb:6WUW|rcsb pdb:1E7B|rcsb pdb:1E7C|rcsb pdb:1E7E|rcsb pdb:1E7F|rcsb pdb:1E7G|rcsb pdb:1E7H|rcsb pdb:1E7I|rcsb pdb:1GNI|rcsb pdb:1GNJ|rcsb pdb:1H9Z|rcsb pdb:1HA2|rcsb pdb:1HK1|rcsb pdb:1HK2|rcsb pdb:1HK3|rcsb pdb:1HK4|rcsb pdb:1HK5|rcsb pdb:1N5U|rcsb pdb:1O9X|rcsb pdb:1TF0|rcsb pdb:1UOR|rcsb pdb:1YSX|rcsb pdb:2BX8|rcsb pdb:2BXA|rcsb pdb:2BXB|rcsb pdb:2BXC|rcsb pdb:2BXD|rcsb pdb:1E7A|rcsb pdb:2BXE|rcsb pdb:2BXF|rcsb pdb:2BXG|rcsb pdb:2BXH|rcsb pdb:2BXI|rcsb pdb:2BXK|rcsb pdb:2BXL|rcsb pdb:2BXM|rcsb pdb:2BXN|rcsb pdb:2BXO|rcsb pdb:2BXP|rcsb pdb:2BXQ|rcsb pdb:2ESG|rcsb pdb:2I2Z|rcsb pdb:2I30|rcsb pdb:2N0X|rcsb pdb:2VDB|rcsb pdb:2VUE|rcsb pdb:2VUF|rcsb pdb:2XSI|rcsb pdb:2XVQ|rcsb pdb:2XVU|rcsb pdb:2XVV|rcsb pdb:2XVW|rcsb pdb:2XW0|rcsb pdb:2XW1|rcsb pdb:2YDF|rcsb pdb:3A73|rcsb pdb:3B9L|rcsb pdb:3B9M|rcsb pdb:3CX9|rcsb pdb:3JQZ|rcsb pdb:3JRY|rcsb pdb:3LU6|rcsb pdb:4HGM|rcsb pdb:4IW1|rcsb pdb:4IW2|rcsb pdb:4K2C|rcsb pdb:4K71|rcsb pdb:4L8U|rcsb pdb:4L9K|rcsb pdb:4L9Q|rcsb pdb:4LA0|rcsb pdb:4LB2|rcsb pdb:4LB9|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4S1Y|rcsb pdb:4Z69|rcsb pdb:5FUO|rcsb pdb:5GIX|rcsb pdb:5GIY|rcsb pdb:5ID7|rcsb pdb:5IFO|rcsb pdb:5IJF|rcsb pdb:5UJB|rcsb pdb:5VNW|rcsb pdb:5X52|rcsb pdb:5YB1|rcsb pdb:5YOQ|rcsb pdb:5Z0B|rcsb pdb:6A7P|rcsb pdb:6EZQ|rcsb pdb:6HSC|rcsb pdb:6JE7|rcsb pdb:6L4K|rcsb pdb:6M4R|rcsb pdb:3LU7|rcsb pdb:3LU8|rcsb pdb:3SQJ|rcsb pdb:3TDL|rcsb pdb:3UIV|rcsb pdb:4BKE|rcsb pdb:4E99|rcsb pdb:4EMX|rcsb pdb:4G03|rcsb pdb:4G04|rcsb pdb:4HGK|rcsb pdb:6M58|rcsb pdb:6M5D|rcsb pdb:6M5E|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R7S|refseq:NP_000468.1|dip:DIP-29902N|mint:MINT-8376102(identity)|uniprotkb:P02768(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:kjtn5mBsCZz/NRkcyW5k3ZWeJBU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:O43795 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-351119|uniprotkb:O43794|uniprotkb:Q7Z6L5|ensembl:ENSP00000306382|ensembl:ENSP00000376132 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:myo1b_human(display_long)|uniprotkb:MYO1B(gene name)|psi-mi:MYO1B(display_short)|uniprotkb:Myosin I alpha(gene name synonym)|uniprotkb:MYH-1c(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001123630.1|refseq:NP_001155291.1|refseq:NP_036355.2|ensembl:ENSG00000128641(gene)|ensembl:ENST00000304164(transcript)|ensembl:ENST00000392318(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030175"(filopodium)|go:"GO:0031982"(vesicle)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O43795|go:"GO:0016459"(myosin complex)|refseq:XP_005246629.1|mint:MINT-8376324(identity)|uniprotkb:O43795(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:FYYccaCMhkmUdTdtq4M8zdpFpV89606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UL03 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1381827|uniprotkb:Q0P664|uniprotkb:Q6PJP4|uniprotkb:Q9UFK0|uniprotkb:Q9Y5M9|ensembl:ENSP00000310260 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:int6_human(display_long)|uniprotkb:INTS6(gene name)|psi-mi:INTS6(display_short)|uniprotkb:DBI1(gene name synonym)|uniprotkb:DDX26(gene name synonym)|uniprotkb:DDX26A(gene name synonym)|uniprotkb:DBI-1(gene name synonym)|uniprotkb:Protein deleted in cancer 1(gene name synonym)|uniprotkb:Protein DDX26(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001035026.1|refseq:NP_001035027.1|refseq:NP_036273.1|refseq:NP_001293020.1|refseq:XP_011533342.1|dip:DIP-38627N|ensembl:ENSG00000102786(gene)|ensembl:ENST00000311234(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR029307|interpro:IPR036465|mint:Q9UL03|rcsb pdb:7CUN|reactome:R-HSA-6807505|mint:MINT-8376252(identity)|uniprotkb:Q9UL03(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:J+sAm/TQd5WHkUw80k7UmX0TSyg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05023 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N|mint:MINT-8376568(identity)|uniprotkb:P05023(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q15029 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-357897|uniprotkb:Q9BUR0|uniprotkb:D3DX58|uniprotkb:B4DK30|ensembl:ENSP00000392094|ensembl:ENSP00000467805|uniprotkb:B4DMC0|uniprotkb:K7EJ81 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:u5s1_human(display_long)|uniprotkb:EFTUD2(gene name)|psi-mi:EFTUD2(display_short)|uniprotkb:KIAA0031(gene name synonym)|uniprotkb:SNRP116(gene name synonym)|uniprotkb:U5 snRNP-specific protein, 116 kDa(gene name synonym)|uniprotkb:Elongation factor Tu GTP-binding domain-containing protein 2(gene name synonym)|uniprotkb:SNU114 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001136077.1|refseq:NP_004238.3|refseq:NP_001245282.1|go:"GO:0042220"(response to cocaine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR041095|interpro:IPR044121|mint:Q15029|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|go:"GO:0035690"|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000108883(gene)|ensembl:ENST00000426333(transcript)|ensembl:ENST00000591382(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030623"(U5 snRNA binding)|refseq:NP_001245283.1|mint:MINT-8376300(identity)|uniprotkb:Q15029(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:/dBQ7TFnGr31AYrb5e215eQ4vfc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q13263 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|mint:MINT-8376230(identity)|uniprotkb:Q13263(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q7Z460 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-913476|uniprotkb:B7ZLX3|uniprotkb:O75118|uniprotkb:Q2KHQ9|uniprotkb:Q5H9P0|uniprotkb:Q8N5B8|uniprotkb:Q9BQT5|ensembl:ENSP00000263710|intact:EBI-2562829|uniprotkb:A2RU21|uniprotkb:F5GWS0|intact:EBI-10967465 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:clap1_human(display_long)|uniprotkb:CLASP1(gene name)|psi-mi:CLASP1(display_short)|uniprotkb:KIAA0622(gene name synonym)|uniprotkb:MAST1(gene name synonym)|uniprotkb:Cytoplasmic linker-associated protein 1(gene name synonym)|uniprotkb:Multiple asters homolog 1(gene name synonym)|uniprotkb:Protein Orbit homolog 1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001135745.1|refseq:NP_001135746.1|refseq:NP_001193980.1|refseq:NP_056097.1|ensembl:ENSG00000074054(gene)|ensembl:ENST00000263710(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0016020"(membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031592"(centrosomal corona)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045180"(basal cortex)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:XP_011509150.1|ensembl:ENSP00000263710|ensembl:ENST00000397587|ensembl:ENSP00000380717|ensembl:ENST00000409078|ensembl:ENSP00000386442|ensembl:ENST00000541377|ensembl:ENSP00000441625|interpro:IPR024395|interpro:IPR028399|interpro:IPR034085|rcsb pdb:4K92|rcsb pdb:6MQ5|rcsb pdb:6MQ7|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-428890|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|mint:MINT-8376522(identity)|uniprotkb:Q7Z460(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ZhVWdhW2ylZHeewHZ63lg5FQT1c9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q14527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654|mint:MINT-8376314(identity)|uniprotkb:Q14527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376112(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376394(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P50416 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2817330|uniprotkb:Q9BWK0|uniprotkb:Q8TCU0|ensembl:ENSP00000265641|ensembl:ENSP00000446108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:cpt1a_human(display_long)|uniprotkb:CPT1A(gene name)|psi-mi:CPT1A(display_short)|uniprotkb:CPT1(gene name synonym)|uniprotkb:Carnitine O-palmitoyltransferase I, liver isoform(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase 1A(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001027017.1|refseq:NP_001867.2|refseq:XP_016872709.1|ensembl:ENSG00000110090(gene)|ensembl:ENST00000265641(transcript)|ensembl:ENST00000539743(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006853"(carnitine shuttle)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0045471"(response to ethanol)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0097421"(liver regeneration)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990698"(palmitoleoyltransferase activity)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR032476|interpro:IPR039551|interpro:IPR042231|mint:P50416|rcsb pdb:2LE3|reactome:R-HSA-1368082|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-5362517|mint:MINT-8376126(identity)|uniprotkb:P50416(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:fmB4d9VHyWPyV0uTf00NkOr/fM49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UH99 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP|mint:MINT-8376110(identity)|uniprotkb:Q9UH99(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9H0A0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-876527|ensembl:ENSP00000257829|uniprotkb:B4DFD5|uniprotkb:E7ESU4|uniprotkb:E9PMN9|uniprotkb:Q86WK5|uniprotkb:Q9C0F4|uniprotkb:Q9HA61|uniprotkb:Q9NVF2 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nat10_human(display_long)|uniprotkb:NAT10(gene name)|psi-mi:NAT10(display_short)|uniprotkb:KIAA1709(gene name synonym)|uniprotkb:ALP(gene name synonym)|uniprotkb:18S rRNA cytosine acetyltransferase(gene name synonym)|uniprotkb:N-acetyltransferase 10(gene name synonym)|uniprotkb:N-acetyltransferase-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000135372(gene)|ensembl:ENST00000257829(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000154"(rRNA modification)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051391"(tRNA acetylation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0106162"(mRNA N-acetyltransferase activity)|go:"GO:1904812"(rRNA acetylation involved in maturation of SSU-rRNA)|go:"GO:1990883"(rRNA cytidine N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR007807(Protein of unknown function DUF699, ATPase putative)|interpro:IPR013562(Region of unknown function DUF1726)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR027992|interpro:IPR032672|interpro:IPR033688|mint:Q9H0A0|rcsb pdb:6VLA|reactome:R-HSA-6790901|refseq:NP_001137502.1|refseq:NP_078938.2|mint:MINT-8376322(identity)|uniprotkb:Q9H0A0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:3eWpscghkRC8Km7mBsUQqjhCKVs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P16615 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N|mint:MINT-8376466(identity)|uniprotkb:P16615(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UHJ3 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|mint:MINT-8376246(identity)|uniprotkb:Q9UHJ3(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376524(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P19338 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226|mint:MINT-8376198(identity)|uniprotkb:P19338(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P02533 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-702178|uniprotkb:Q14715|uniprotkb:Q53XY3|uniprotkb:Q9BUE3|uniprotkb:Q9UBN2|uniprotkb:Q9UBN3|uniprotkb:Q9UCY4|ensembl:ENSP00000167586 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:k1c14_human(display_long)|uniprotkb:Cytokeratin-14(gene name synonym)|uniprotkb:KRT14(gene name)|psi-mi:KRT14(display_short)|uniprotkb:Keratin-14(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_000517.2|dip:DIP-33874N|ensembl:ENSG00000186847(gene)|ensembl:ENST00000167586(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007568"(aging)|go:"GO:0008544"(epidermis development)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042633"(hair cycle)|go:"GO:0045095"(keratin filament)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045178"(basal part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990254"(keratin filament binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P02533|rcsb pdb:3TNU|rcsb pdb:6JFV|reactome:R-HSA-446107|reactome:R-HSA-6805567|reactome:R-HSA-6809371|mint:MINT-8376060(identity)|uniprotkb:P02533(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:IO1k6S8FB65jQr4GNwhKuxZ1ohg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P43246 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N|mint:MINT-8376228(identity)|uniprotkb:P43246(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P17066 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695|mint:MINT-8376106(identity)|uniprotkb:P17066(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9NR30 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol)|mint:MINT-8376212(identity)|uniprotkb:Q9NR30(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376444(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P09874 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N|mint:MINT-8376280(identity)|uniprotkb:P09874(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q13263 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|mint:MINT-8376274(identity)|uniprotkb:Q13263(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P50416 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2817330|uniprotkb:Q9BWK0|uniprotkb:Q8TCU0|ensembl:ENSP00000265641|ensembl:ENSP00000446108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:cpt1a_human(display_long)|uniprotkb:CPT1A(gene name)|psi-mi:CPT1A(display_short)|uniprotkb:CPT1(gene name synonym)|uniprotkb:Carnitine O-palmitoyltransferase I, liver isoform(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase 1A(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001027017.1|refseq:NP_001867.2|refseq:XP_016872709.1|ensembl:ENSG00000110090(gene)|ensembl:ENST00000265641(transcript)|ensembl:ENST00000539743(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006853"(carnitine shuttle)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0045471"(response to ethanol)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0097421"(liver regeneration)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990698"(palmitoleoyltransferase activity)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR032476|interpro:IPR039551|interpro:IPR042231|mint:P50416|rcsb pdb:2LE3|reactome:R-HSA-1368082|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-5362517|mint:MINT-8376108(identity)|uniprotkb:P50416(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:fmB4d9VHyWPyV0uTf00NkOr/fM49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q14527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654|mint:MINT-8376328(identity)|uniprotkb:Q14527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q00325 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|mint:MINT-8376334(identity)|uniprotkb:Q00325(original identifier) go:"GO:0005634"(nucleus) - crc64:78714C85931B22D5 figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q7Z460 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-913476|uniprotkb:B7ZLX3|uniprotkb:O75118|uniprotkb:Q2KHQ9|uniprotkb:Q5H9P0|uniprotkb:Q8N5B8|uniprotkb:Q9BQT5|ensembl:ENSP00000263710|intact:EBI-2562829|uniprotkb:A2RU21|uniprotkb:F5GWS0|intact:EBI-10967465 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:clap1_human(display_long)|uniprotkb:CLASP1(gene name)|psi-mi:CLASP1(display_short)|uniprotkb:KIAA0622(gene name synonym)|uniprotkb:MAST1(gene name synonym)|uniprotkb:Cytoplasmic linker-associated protein 1(gene name synonym)|uniprotkb:Multiple asters homolog 1(gene name synonym)|uniprotkb:Protein Orbit homolog 1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001135745.1|refseq:NP_001135746.1|refseq:NP_001193980.1|refseq:NP_056097.1|ensembl:ENSG00000074054(gene)|ensembl:ENST00000263710(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0016020"(membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031592"(centrosomal corona)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045180"(basal cortex)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:XP_011509150.1|ensembl:ENSP00000263710|ensembl:ENST00000397587|ensembl:ENSP00000380717|ensembl:ENST00000409078|ensembl:ENSP00000386442|ensembl:ENST00000541377|ensembl:ENSP00000441625|interpro:IPR024395|interpro:IPR028399|interpro:IPR034085|rcsb pdb:4K92|rcsb pdb:6MQ5|rcsb pdb:6MQ7|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-428890|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|mint:MINT-8376390(identity)|uniprotkb:Q7Z460(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ZhVWdhW2ylZHeewHZ63lg5FQT1c9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P16615 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N|mint:MINT-8376546(identity)|uniprotkb:P16615(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P38646 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N|mint:MINT-8376054(identity)|uniprotkb:P38646(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q00325 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|mint:MINT-8376432(identity)|uniprotkb:Q00325(original identifier) go:"GO:0005634"(nucleus) - crc64:78714C85931B22D5 figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9BX10 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-6115579|uniprotkb:Q5T7E8|uniprotkb:Q8ND84|uniprotkb:Q8TAH7|uniprotkb:Q8WUA5|uniprotkb:Q9HCS9|uniprotkb:Q9NRU4|uniprotkb:Q9NX60|ensembl:ENSP00000303997 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:gtpb2_human(display_long)|uniprotkb:GTPBP2(gene name)|psi-mi:GTPBP2(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001273145.1|refseq:NP_061969.3|ensembl:ENSG00000172432(gene)|ensembl:ENST00000307126(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006414"(translational elongation)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0042802"(identical protein binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR035531|mint:Q9BX10|reactome:R-HSA-114608|mint:MINT-8376210(identity)|uniprotkb:Q9BX10(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:7+hRdMs+O0Al9NjtcPI0Re/Pc6Q9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P02768 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-714423|ensembl:ENSP00000295897|uniprotkb:Q645G4|uniprotkb:O95574|uniprotkb:P04277|uniprotkb:Q13140|uniprotkb:Q68DN5|uniprotkb:Q6UXK4|uniprotkb:Q86YG0|uniprotkb:Q9P157|uniprotkb:Q9P1I7|uniprotkb:Q9UHS3|uniprotkb:Q9UJZ0|intact:EBI-7301844|intact:MINT-1161169|uniprotkb:E7ESS9|uniprotkb:Q8IUK7 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:albu_human(display_long)|uniprotkb:GIG42(orf name)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:PRO0903(orf name)|uniprotkb:PRO1708(orf name)|uniprotkb:PRO2044(orf name)|uniprotkb:PRO2619(orf name)|uniprotkb:PRO2675(orf name)|uniprotkb:UNQ696/PRO1341(orf name)|uniprotkb:GIG20(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000163631(gene)|ensembl:ENST00000295897(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:1E78|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051087"(chaperone binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P02768|rcsb pdb:1AO6|rcsb pdb:1BJ5|rcsb pdb:1BKE|rcsb pdb:1BM0|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|rcsb pdb:6XV0|rcsb pdb:6YG9|rcsb pdb:6ZL1|rcsb pdb:7A9C|rcsb pdb:7AAE|rcsb pdb:7AAI|rcsb pdb:7D6J|rcsb pdb:7JWN|reactome:R-HSA-114608|reactome:R-HSA-159418|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2168880|reactome:R-HSA-381426|reactome:R-HSA-879518|reactome:R-HSA-8957275|reactome:R-HSA-8964058|reactome:R-HSA-9707564|rcsb pdb:6WUW|rcsb pdb:1E7B|rcsb pdb:1E7C|rcsb pdb:1E7E|rcsb pdb:1E7F|rcsb pdb:1E7G|rcsb pdb:1E7H|rcsb pdb:1E7I|rcsb pdb:1GNI|rcsb pdb:1GNJ|rcsb pdb:1H9Z|rcsb pdb:1HA2|rcsb pdb:1HK1|rcsb pdb:1HK2|rcsb pdb:1HK3|rcsb pdb:1HK4|rcsb pdb:1HK5|rcsb pdb:1N5U|rcsb pdb:1O9X|rcsb pdb:1TF0|rcsb pdb:1UOR|rcsb pdb:1YSX|rcsb pdb:2BX8|rcsb pdb:2BXA|rcsb pdb:2BXB|rcsb pdb:2BXC|rcsb pdb:2BXD|rcsb pdb:1E7A|rcsb pdb:2BXE|rcsb pdb:2BXF|rcsb pdb:2BXG|rcsb pdb:2BXH|rcsb pdb:2BXI|rcsb pdb:2BXK|rcsb pdb:2BXL|rcsb pdb:2BXM|rcsb pdb:2BXN|rcsb pdb:2BXO|rcsb pdb:2BXP|rcsb pdb:2BXQ|rcsb pdb:2ESG|rcsb pdb:2I2Z|rcsb pdb:2I30|rcsb pdb:2N0X|rcsb pdb:2VDB|rcsb pdb:2VUE|rcsb pdb:2VUF|rcsb pdb:2XSI|rcsb pdb:2XVQ|rcsb pdb:2XVU|rcsb pdb:2XVV|rcsb pdb:2XVW|rcsb pdb:2XW0|rcsb pdb:2XW1|rcsb pdb:2YDF|rcsb pdb:3A73|rcsb pdb:3B9L|rcsb pdb:3B9M|rcsb pdb:3CX9|rcsb pdb:3JQZ|rcsb pdb:3JRY|rcsb pdb:3LU6|rcsb pdb:4HGM|rcsb pdb:4IW1|rcsb pdb:4IW2|rcsb pdb:4K2C|rcsb pdb:4K71|rcsb pdb:4L8U|rcsb pdb:4L9K|rcsb pdb:4L9Q|rcsb pdb:4LA0|rcsb pdb:4LB2|rcsb pdb:4LB9|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4S1Y|rcsb pdb:4Z69|rcsb pdb:5FUO|rcsb pdb:5GIX|rcsb pdb:5GIY|rcsb pdb:5ID7|rcsb pdb:5IFO|rcsb pdb:5IJF|rcsb pdb:5UJB|rcsb pdb:5VNW|rcsb pdb:5X52|rcsb pdb:5YB1|rcsb pdb:5YOQ|rcsb pdb:5Z0B|rcsb pdb:6A7P|rcsb pdb:6EZQ|rcsb pdb:6HSC|rcsb pdb:6JE7|rcsb pdb:6L4K|rcsb pdb:6M4R|rcsb pdb:3LU7|rcsb pdb:3LU8|rcsb pdb:3SQJ|rcsb pdb:3TDL|rcsb pdb:3UIV|rcsb pdb:4BKE|rcsb pdb:4E99|rcsb pdb:4EMX|rcsb pdb:4G03|rcsb pdb:4G04|rcsb pdb:4HGK|rcsb pdb:6M58|rcsb pdb:6M5D|rcsb pdb:6M5E|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R7S|refseq:NP_000468.1|dip:DIP-29902N|mint:MINT-8376186(identity)|uniprotkb:P02768(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:kjtn5mBsCZz/NRkcyW5k3ZWeJBU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376422(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9Y3T9 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756|mint:MINT-8376168(identity)|uniprotkb:Q9Y3T9(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9Y4W6 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000141385(gene)|ensembl:ENST00000269143(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|refseq:NP_006787.2|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664|mint:MINT-8376098(identity)|uniprotkb:Q9Y4W6(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376276(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P11021 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N|mint:MINT-8376078(identity)|uniprotkb:P11021(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P22105 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2821024|uniprotkb:Q9UC12|uniprotkb:Q5ST74|uniprotkb:Q08AM0|uniprotkb:Q9NPK9|uniprotkb:Q9UC11|uniprotkb:Q59GU7|uniprotkb:P78530|uniprotkb:Q9UC10|uniprotkb:Q08424|uniprotkb:Q9UMG7|uniprotkb:Q08AM1|uniprotkb:Q7L8Q4|uniprotkb:Q9UC13|uniprotkb:Q5SQD3|uniprotkb:Q8N4R1|uniprotkb:P78531|ensembl:ENSP00000364393|ensembl:ENSP00000447694|ensembl:ENSP00000448326|ensembl:ENSP00000496448 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:tenx_human(display_long)|uniprotkb:TNXB(gene name)|psi-mi:TNXB(display_short)|uniprotkb:HXBL(gene name synonym)|uniprotkb:TNX(gene name synonym)|uniprotkb:TNXB1(gene name synonym)|uniprotkb:TNXB2(gene name synonym)|uniprotkb:XB(gene name synonym)|uniprotkb:Hexabrachion-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_061978.6|refseq:NP_115859.2|ensembl:ENSG00000168477(gene)|ensembl:ENSG00000229353(gene)|ensembl:ENSG00000236236(gene)|ensembl:ENST00000375244(transcript)|ensembl:ENST00000546684(transcript)|ensembl:ENST00000550539(transcript)|ensembl:ENST00000644971(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098633"(collagen fibril binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR033081|interpro:IPR036056|interpro:IPR036116|interpro:IPR041161|mint:P22105|rcsb pdb:2CUH|rcsb pdb:2CUI|rcsb pdb:2CUM|reactome:R-HSA-3000178|mint:MINT-8376406(identity)|uniprotkb:P22105(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:5O4kj1Cs1NRP1yGON0AEupG2l+M9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376350(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9BQG0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924|mint:MINT-8376358(identity)|uniprotkb:Q9BQG0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12235 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N|mint:MINT-8376326(identity)|uniprotkb:P12235(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376578(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12956 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N|mint:MINT-8376100(identity)|uniprotkb:P12956(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q92621 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N|mint:MINT-8376418(identity)|uniprotkb:Q92621(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UM47 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_000426.2|ensembl:ENSP00000263388|dip:DIP-39827N|ensembl:ENSG00000074181(gene)|ensembl:ENST00000263388(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0050793"(regulation of developmental process)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802|mint:MINT-8376492(identity)|uniprotkb:Q9UM47(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9NRZ9 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1056215|uniprotkb:Q3LID1|uniprotkb:Q6I7N7|uniprotkb:Q76H76|uniprotkb:Q76H77|uniprotkb:Q76H78|uniprotkb:Q76H79|uniprotkb:Q76H80|uniprotkb:Q76H81|uniprotkb:Q7Z397|uniprotkb:Q7Z5X2|uniprotkb:Q8N6P4|uniprotkb:Q9H4P5|uniprotkb:B2RB41|ensembl:ENSP00000239027 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:hells_human(display_long)|uniprotkb:HELLS(gene name)|psi-mi:HELLS(display_short)|uniprotkb:SMARCA6(gene name synonym)|uniprotkb:PASG(gene name synonym)|uniprotkb:Nbla10143(orf name)|uniprotkb:SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6(gene name synonym)|uniprotkb:Proliferation-associated SNF2-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_060533.2|refseq:NP_001275996.1|refseq:NP_001275997.1|refseq:NP_001275998.1|refseq:NP_001275999.1|refseq:NP_001276000.1|refseq:NP_001276001.1|refseq:NP_001276002.1|refseq:NP_001276003.1|refseq:NP_001276004.1|ensembl:ENSG00000119969(gene)|ensembl:ENST00000348459(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001655"(urogenital system development)|go:"GO:0003682"(chromatin binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|interpro:IPR044753|mint:Q9NRZ9|mint:MINT-8376196(identity)|uniprotkb:Q9NRZ9(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:QhCAini69BkBNF7TwsA0pflATBk9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9Y3X0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2557532|ensembl:ENSP00000221922 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ccdc9_human(display_long)|uniprotkb:CCDC9(gene name)|psi-mi:CCDC9(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_056418.1|ensembl:ENSG00000105321(gene)|ensembl:ENST00000221922(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR029336|refseq:XP_016882067.1|mint:MINT-8376222(identity)|uniprotkb:Q9Y3X0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ieUMcjasYCi2p57TSacQTDs7nSo9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376218(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12235 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N|mint:MINT-8376260(identity)|uniprotkb:P12235(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P11021 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N|mint:MINT-8376050(identity)|uniprotkb:P11021(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9BQG0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924|mint:MINT-8376342(identity)|uniprotkb:Q9BQG0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q96RE9 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2826684|uniprotkb:B3KU35|uniprotkb:Q17RP3|uniprotkb:Q5H9N5|uniprotkb:A8MY91|uniprotkb:B4DU78|uniprotkb:Q06DQ3|ensembl:ENSP00000274599|uniprotkb:F5GWS1 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:zn300_human(display_long)|uniprotkb:ZNF300(gene name)|psi-mi:ZNF300(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001166302.1|refseq:NP_001166303.1|refseq:NP_443092.1|ensembl:ENSG00000145908(gene)|ensembl:ENST00000274599(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|mint:MINT-8376518(identity)|uniprotkb:Q96RE9(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:38iNcXE1eJW5dyX9zAN46FoXT589606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376464(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376374(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9Y4A5 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-399128|uniprotkb:O75218|uniprotkb:Q9Y631|uniprotkb:Q9Y6H4|uniprotkb:A4D265|ensembl:ENSP00000352925 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:trrap_human(display_long)|uniprotkb:TRRAP(gene name)|psi-mi:TRRAP(display_short)|uniprotkb:PAF400(gene name synonym)|uniprotkb:350/400 kDa PCAF-associated factor(gene name synonym)|uniprotkb:STAF40(gene name synonym)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_003487.1|ensembl:ENSG00000196367(gene)|ensembl:ENST00000359863(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016310"(phosphorylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|mint:Q9Y4A5|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_001231509.1|dip:DIP-28149N|mint:MINT-8376456(identity)|uniprotkb:Q9Y4A5(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:bGoQLXxMT0zZ0jVW+2s4hUwnBA49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9H0A0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-876527|ensembl:ENSP00000257829|uniprotkb:B4DFD5|uniprotkb:E7ESU4|uniprotkb:E9PMN9|uniprotkb:Q86WK5|uniprotkb:Q9C0F4|uniprotkb:Q9HA61|uniprotkb:Q9NVF2 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nat10_human(display_long)|uniprotkb:NAT10(gene name)|psi-mi:NAT10(display_short)|uniprotkb:KIAA1709(gene name synonym)|uniprotkb:ALP(gene name synonym)|uniprotkb:18S rRNA cytosine acetyltransferase(gene name synonym)|uniprotkb:N-acetyltransferase 10(gene name synonym)|uniprotkb:N-acetyltransferase-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000135372(gene)|ensembl:ENST00000257829(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000154"(rRNA modification)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051391"(tRNA acetylation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0106162"(mRNA N-acetyltransferase activity)|go:"GO:1904812"(rRNA acetylation involved in maturation of SSU-rRNA)|go:"GO:1990883"(rRNA cytidine N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR007807(Protein of unknown function DUF699, ATPase putative)|interpro:IPR013562(Region of unknown function DUF1726)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR027992|interpro:IPR032672|interpro:IPR033688|mint:Q9H0A0|rcsb pdb:6VLA|reactome:R-HSA-6790901|refseq:NP_001137502.1|refseq:NP_078938.2|mint:MINT-8376262(identity)|uniprotkb:Q9H0A0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:3eWpscghkRC8Km7mBsUQqjhCKVs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12956 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N|mint:MINT-8376052(identity)|uniprotkb:P12956(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q92621 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N|mint:MINT-8376428(identity)|uniprotkb:Q92621(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P46977 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472|ensembl:ENSP00000436962|ensembl:ENSP00000497336|uniprotkb:B4DJ24|uniprotkb:E9PNQ1 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_689926.1|ensembl:ENSG00000134910(gene)|ensembl:ENST00000392708(transcript)|ensembl:ENST00000529196(transcript)|ensembl:ENST00000649491(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035000"(oligosaccharyltransferase III complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:P46977|rcsb pdb:6S7O|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:XP_011541109.1|refseq:NP_001265432.1|refseq:NP_001265433.1|mint:MINT-8376566(identity)|uniprotkb:P46977(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UQR1 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2688184|uniprotkb:Q58EY5|uniprotkb:O43591|uniprotkb:O00389|uniprotkb:D3DN27|ensembl:ENSP00000420448|ensembl:ENSP00000353863|ensembl:ENSP00000419322|ensembl:ENSP00000420335|uniprotkb:Q6PJ98 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:zn148_human(display_long)|uniprotkb:ZBP89(gene name synonym)|uniprotkb:Transcription factor ZBP-89(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein 89(gene name synonym)|uniprotkb:ZNF148(gene name)|psi-mi:ZNF148(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_068799.2|ensembl:ENST00000360647(transcript)|ensembl:ENST00000484491(transcript)|ensembl:ENST00000485866(transcript)|ensembl:ENST00000492394(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006968"(cellular defense response)|go:"GO:0007276"(gamete generation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0021762"(substantia nigra development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9UQR1|ensembl:ENSG00000163848(gene)|refseq:NP_001335353.1|refseq:NP_001335354.1|refseq:NP_001335355.1|refseq:NP_001335356.1|refseq:NP_001335357.1|refseq:NP_001335358.1|refseq:NP_001335359.1|refseq:NP_001335360.1|refseq:NP_001335361.1|refseq:NP_001335362.1|ensembl:ENSP00000353863|ensembl:ENSP00000420335|ensembl:ENSP00000420448|ensembl:ENSP00000419322|mint:MINT-8376258(identity)|uniprotkb:Q9UQR1(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:2H8lAaonZqAnCWDtUN8q55+03h49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P42704 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N|mint:MINT-8376356(identity)|uniprotkb:P42704(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q6P1M0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_005085.2|ensembl:ENSG00000167114(gene)|ensembl:ENST00000300456(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001579"(medium-chain fatty acid transport)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0062003"(negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR030304|interpro:IPR042099|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:XP_016869711.1|mint:MINT-8376544(identity)|uniprotkb:Q6P1M0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9NXE4 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-372102|uniprotkb:Q6FI76|uniprotkb:Q6P1P7|uniprotkb:Q6ZT43|uniprotkb:Q9H0M2|uniprotkb:Q9NW20|uniprotkb:Q9NWL2|uniprotkb:Q9P2C9|uniprotkb:B4DWK7|uniprotkb:E9PCE6|intact:EBI-1058838|ensembl:ENSP00000386531|uniprotkb:B4DRB8|uniprotkb:E7ESA2|uniprotkb:B4DM23|uniprotkb:B4DQ31|uniprotkb:B4E0L6|uniprotkb:B1PBA3 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nsma3_human(display_long)|uniprotkb:SKNY(gene name synonym)|uniprotkb:SMPD4(gene name)|psi-mi:SMPD4(display_short)|uniprotkb:Neutral sphingomyelinase 3(gene name synonym)|uniprotkb:Neutral sphingomyelinase III(gene name synonym)|uniprotkb:KIAA1418(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001164554.1|refseq:NP_060221.2|refseq:XP_011509747.1|refseq:NP_060421.2|ensembl:ENSG00000136699(gene)|ensembl:ENST00000409031(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004767"(sphingomyelin phosphodiesterase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006685"(sphingomyelin catabolic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050290"(sphingomyelin phosphodiesterase D activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR024129|reactome:R-HSA-1660662|refseq:XP_016859937.1|refseq:XP_016859938.1|mint:MINT-8376130(identity)|uniprotkb:Q9NXE4(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:/OGzQcEQfrn7jgedtceXIuns7449606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376192(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9NVI7 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352007|ensembl:ENSP00000368030|uniprotkb:Q5SV23|uniprotkb:Q8N275|uniprotkb:Q96A50|uniprotkb:B3KPB3|uniprotkb:D2K8Q1|uniprotkb:G3V1I6 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:atd3a_human(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001164006.1|refseq:NP_001164007.1|refseq:NP_060658.3|ensembl:ENSG00000197785(gene)|ensembl:ENST00000378755(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q9NVI7|dip:DIP-33194N|mint:MINT-8376384(identity)|uniprotkb:Q9NVI7(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:IZKJEVLLS/DFINgBgO5frizN1P49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12236 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2|mint:MINT-8376504(identity)|uniprotkb:P12236(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P11166 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-717153|uniprotkb:A8K9S6|uniprotkb:O75535|uniprotkb:Q147X2|uniprotkb:B2R620|uniprotkb:D3DPX0|uniprotkb:Q0P512|ensembl:ENSP00000416293 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:gtr1_human(display_long)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)|uniprotkb:HepG2 glucose transporter(gene name synonym)|uniprotkb:SLC2A1(gene name)|psi-mi:SLC2A1(display_short)|uniprotkb:GLUT1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_006507.2|ensembl:ENSG00000117394(gene)|ensembl:ENST00000426263(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0072562"(blood microparticle)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11166|rcsb pdb:1SUK|rcsb pdb:4PYP|rcsb pdb:5EQG|rcsb pdb:5EQH|rcsb pdb:5EQI|rcsb pdb:6THA|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-422356|reactome:R-HSA-5619043|reactome:R-HSA-5653890|dip:DIP-23N|mint:MINT-8376454(identity)|uniprotkb:P11166(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:72DLUG1CFkqcf92goIZBZ4+zuls9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UBM7 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1054468|uniprotkb:O60492|uniprotkb:O60717|uniprotkb:B2R6Z2|ensembl:ENSP00000347717|ensembl:ENSP00000384739 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:dhcr7_human(display_long)|uniprotkb:"Sterol Delta(7)-reductase"(gene name synonym)|uniprotkb:DHCR7(gene name)|psi-mi:DHCR7(display_short)|uniprotkb:D7SR(gene name synonym)|uniprotkb:Delta7-sterol reductase(gene name synonym)|uniprotkb:Sterol reductase SR-2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001157289.1|refseq:NP_001351.2|mint:Q9UBM7|reactome:R-HSA-2426168|reactome:R-HSA-6807047|reactome:R-HSA-6807062|interpro:IPR018083|ensembl:ENSG00000172893(gene)|ensembl:ENST00000355527(transcript)|ensembl:ENST00000407721(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0009918"(sterol delta7 reductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016132"(brassinosteroid biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0047598"(7-dehydrocholesterol reductase activity)|go:"GO:0050661"(NADP binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|mint:MINT-8376564(identity)|uniprotkb:Q9UBM7(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:op53bBpGaOM0Ysy4Bn5q6qXcKgI9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376290(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9BQG0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924|mint:MINT-8376412(identity)|uniprotkb:Q9BQG0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376056(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12235 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N|mint:MINT-8376140(identity)|uniprotkb:P12235(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P22105 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2821024|uniprotkb:Q9UC12|uniprotkb:Q5ST74|uniprotkb:Q08AM0|uniprotkb:Q9NPK9|uniprotkb:Q9UC11|uniprotkb:Q59GU7|uniprotkb:P78530|uniprotkb:Q9UC10|uniprotkb:Q08424|uniprotkb:Q9UMG7|uniprotkb:Q08AM1|uniprotkb:Q7L8Q4|uniprotkb:Q9UC13|uniprotkb:Q5SQD3|uniprotkb:Q8N4R1|uniprotkb:P78531|ensembl:ENSP00000364393|ensembl:ENSP00000447694|ensembl:ENSP00000448326|ensembl:ENSP00000496448 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:tenx_human(display_long)|uniprotkb:TNXB(gene name)|psi-mi:TNXB(display_short)|uniprotkb:HXBL(gene name synonym)|uniprotkb:TNX(gene name synonym)|uniprotkb:TNXB1(gene name synonym)|uniprotkb:TNXB2(gene name synonym)|uniprotkb:XB(gene name synonym)|uniprotkb:Hexabrachion-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_061978.6|refseq:NP_115859.2|ensembl:ENSG00000168477(gene)|ensembl:ENSG00000229353(gene)|ensembl:ENSG00000236236(gene)|ensembl:ENST00000375244(transcript)|ensembl:ENST00000546684(transcript)|ensembl:ENST00000550539(transcript)|ensembl:ENST00000644971(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098633"(collagen fibril binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR033081|interpro:IPR036056|interpro:IPR036116|interpro:IPR041161|mint:P22105|rcsb pdb:2CUH|rcsb pdb:2CUI|rcsb pdb:2CUM|reactome:R-HSA-3000178|mint:MINT-8376460(identity)|uniprotkb:P22105(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:5O4kj1Cs1NRP1yGON0AEupG2l+M9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9NR30 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol)|mint:MINT-8376172(identity)|uniprotkb:Q9NR30(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q16891 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N|mint:MINT-8376152(identity)|uniprotkb:Q16891(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:O00767 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2684237|uniprotkb:Q5W037|uniprotkb:B2R5U0|uniprotkb:Q96KF6|uniprotkb:Q53GR9|uniprotkb:Q9Y695|uniprotkb:Q9BS07|uniprotkb:Q16150|uniprotkb:Q6GSS4|uniprotkb:Q5W038|uniprotkb:D3DR68|ensembl:ENSP00000359380 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:scd_human(display_long)|uniprotkb:"Delta(9)-desaturase"(gene name synonym)|uniprotkb:Fatty acid desaturase(gene name synonym)|uniprotkb:Acyl-CoA desaturase(gene name synonym)|uniprotkb:FADS5(gene name synonym)|uniprotkb:SCD1(gene name synonym)|uniprotkb:SCDOS(gene name synonym)|uniprotkb:SCD(gene name)|psi-mi:SCD(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_005054.3|ensembl:ENSG00000099194(gene)|ensembl:ENST00000370355(transcript)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032896"(palmitoyl-CoA 9-desaturase activity)|go:"GO:0070542"(response to fatty acid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903966"(monounsaturated fatty acid biosynthetic process)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|rcsb pdb:4ZYO|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|mint:MINT-8376512(identity)|uniprotkb:O00767(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:GeF7PMgZb07js39m6ykSSmFuIUA9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9Y4A5 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-399128|uniprotkb:O75218|uniprotkb:Q9Y631|uniprotkb:Q9Y6H4|uniprotkb:A4D265|ensembl:ENSP00000352925 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:trrap_human(display_long)|uniprotkb:TRRAP(gene name)|psi-mi:TRRAP(display_short)|uniprotkb:PAF400(gene name synonym)|uniprotkb:350/400 kDa PCAF-associated factor(gene name synonym)|uniprotkb:STAF40(gene name synonym)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_003487.1|ensembl:ENSG00000196367(gene)|ensembl:ENST00000359863(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016310"(phosphorylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|mint:Q9Y4A5|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_001231509.1|dip:DIP-28149N|mint:MINT-8376484(identity)|uniprotkb:Q9Y4A5(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:bGoQLXxMT0zZ0jVW+2s4hUwnBA49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12236 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2|mint:MINT-8376482(identity)|uniprotkb:P12236(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P02786 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N|mint:MINT-8376176(identity)|uniprotkb:P02786(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q75T13 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1055128|uniprotkb:Q4G0R8|uniprotkb:Q4ZG47|uniprotkb:Q53SM0|uniprotkb:Q6AW92|uniprotkb:Q6UWV4|uniprotkb:Q9HA24|ensembl:ENSP00000346809 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:pgap1_human(display_long)|uniprotkb:Post-GPI attachment to proteins factor 1(gene name synonym)|uniprotkb:PGAP1(gene name)|psi-mi:PGAP1(display_short)|uniprotkb:UNQ3024/PRO9822(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001308028.1|refseq:NP_001308029.1|refseq:NP_079265.2|ensembl:ENSG00000197121(gene)|ensembl:ENST00000354764(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006505"(GPI anchor metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0021871"(forebrain regionalization)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0050185"(phosphatidylinositol deacylase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR012908(PGAP1-like)|interpro:IPR029058|interpro:IPR039529|mint:Q75T13|reactome:R-HSA-162791|refseq:XP_016860481.1|refseq:XP_016860482.1|mint:MINT-8376520(identity)|uniprotkb:Q75T13(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:mOh9dmfjLrZWaalO2QnERu+HPw49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q00325 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|mint:MINT-8376490(identity)|uniprotkb:Q00325(original identifier) go:"GO:0005634"(nucleus) - crc64:78714C85931B22D5 figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q92621 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N|mint:MINT-8376450(identity)|uniprotkb:Q92621(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P43243 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1|mint:MINT-8376286(identity)|uniprotkb:P43243(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9NXE4 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-372102|uniprotkb:Q6FI76|uniprotkb:Q6P1P7|uniprotkb:Q6ZT43|uniprotkb:Q9H0M2|uniprotkb:Q9NW20|uniprotkb:Q9NWL2|uniprotkb:Q9P2C9|uniprotkb:B4DWK7|uniprotkb:E9PCE6|intact:EBI-1058838|ensembl:ENSP00000386531|uniprotkb:B4DRB8|uniprotkb:E7ESA2|uniprotkb:B4DM23|uniprotkb:B4DQ31|uniprotkb:B4E0L6|uniprotkb:B1PBA3 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nsma3_human(display_long)|uniprotkb:SKNY(gene name synonym)|uniprotkb:SMPD4(gene name)|psi-mi:SMPD4(display_short)|uniprotkb:Neutral sphingomyelinase 3(gene name synonym)|uniprotkb:Neutral sphingomyelinase III(gene name synonym)|uniprotkb:KIAA1418(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001164554.1|refseq:NP_060221.2|refseq:XP_011509747.1|refseq:NP_060421.2|ensembl:ENSG00000136699(gene)|ensembl:ENST00000409031(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004767"(sphingomyelin phosphodiesterase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006685"(sphingomyelin catabolic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050290"(sphingomyelin phosphodiesterase D activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR024129|reactome:R-HSA-1660662|refseq:XP_016859937.1|refseq:XP_016859938.1|mint:MINT-8376138(identity)|uniprotkb:Q9NXE4(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:/OGzQcEQfrn7jgedtceXIuns7449606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P42704 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N|mint:MINT-8376376(identity)|uniprotkb:P42704(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376502(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376164(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P11166 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-717153|uniprotkb:A8K9S6|uniprotkb:O75535|uniprotkb:Q147X2|uniprotkb:B2R620|uniprotkb:D3DPX0|uniprotkb:Q0P512|ensembl:ENSP00000416293 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:gtr1_human(display_long)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)|uniprotkb:HepG2 glucose transporter(gene name synonym)|uniprotkb:SLC2A1(gene name)|psi-mi:SLC2A1(display_short)|uniprotkb:GLUT1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_006507.2|ensembl:ENSG00000117394(gene)|ensembl:ENST00000426263(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0072562"(blood microparticle)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11166|rcsb pdb:1SUK|rcsb pdb:4PYP|rcsb pdb:5EQG|rcsb pdb:5EQH|rcsb pdb:5EQI|rcsb pdb:6THA|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-422356|reactome:R-HSA-5619043|reactome:R-HSA-5653890|dip:DIP-23N|mint:MINT-8376434(identity)|uniprotkb:P11166(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:72DLUG1CFkqcf92goIZBZ4+zuls9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q16531 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N|mint:MINT-8376340(identity)|uniprotkb:Q16531(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12236 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2|mint:MINT-8376526(identity)|uniprotkb:P12236(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q96RE9 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2826684|uniprotkb:B3KU35|uniprotkb:Q17RP3|uniprotkb:Q5H9N5|uniprotkb:A8MY91|uniprotkb:B4DU78|uniprotkb:Q06DQ3|ensembl:ENSP00000274599|uniprotkb:F5GWS1 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:zn300_human(display_long)|uniprotkb:ZNF300(gene name)|psi-mi:ZNF300(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001166302.1|refseq:NP_001166303.1|refseq:NP_443092.1|ensembl:ENSG00000145908(gene)|ensembl:ENST00000274599(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|mint:MINT-8376496(identity)|uniprotkb:Q96RE9(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:38iNcXE1eJW5dyX9zAN46FoXT589606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376320(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9BQG0 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924|mint:MINT-8376396(identity)|uniprotkb:Q9BQG0(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P36406 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|mint:MINT-8376368(identity)|uniprotkb:P36406(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P02786 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N|mint:MINT-8376158(identity)|uniprotkb:P02786(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9Y4A5 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-399128|uniprotkb:O75218|uniprotkb:Q9Y631|uniprotkb:Q9Y6H4|uniprotkb:A4D265|ensembl:ENSP00000352925 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:trrap_human(display_long)|uniprotkb:TRRAP(gene name)|psi-mi:TRRAP(display_short)|uniprotkb:PAF400(gene name synonym)|uniprotkb:350/400 kDa PCAF-associated factor(gene name synonym)|uniprotkb:STAF40(gene name synonym)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_003487.1|ensembl:ENSG00000196367(gene)|ensembl:ENST00000359863(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016310"(phosphorylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|mint:Q9Y4A5|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_001231509.1|dip:DIP-28149N|mint:MINT-8376508(identity)|uniprotkb:Q9Y4A5(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:bGoQLXxMT0zZ0jVW+2s4hUwnBA49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P04264 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-298429|uniprotkb:Q14720|uniprotkb:Q6GSJ0|uniprotkb:B2RA01|uniprotkb:Q9H298|ensembl:ENSP00000252244|uniprotkb:P85925|uniprotkb:P86104 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:k2c1_human(display_long)|uniprotkb:KRT1(gene name)|psi-mi:KRT1(display_short)|uniprotkb:KRTA(gene name synonym)|uniprotkb:Keratin-1(gene name synonym)|uniprotkb:Cytokeratin-1(gene name synonym)|uniprotkb:67 kDa cytokeratin(gene name synonym)|uniprotkb:Hair alpha protein(gene name synonym)|uniprotkb:Type-II keratin Kb1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_006112.3|ensembl:ENSG00000167768(gene)|ensembl:ENST00000252244(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045095"(keratin filament)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR032449|interpro:IPR039008|mint:P04264|rcsb pdb:4ZRY|rcsb pdb:6E2J|rcsb pdb:6UUI|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|mint:MINT-8376530(identity)|uniprotkb:P04264(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:TeAC3i2hWTS2lgXT0i4agp9nv349606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:O75132 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2860059|uniprotkb:B2RZH1|uniprotkb:Q9UGG8|uniprotkb:Q1ECU0|ensembl:ENSP00000216268 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:zbed4_human(display_long)|uniprotkb:ZBED4(gene name)|psi-mi:ZBED4(display_short)|uniprotkb:KIAA0637(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_055653.2|ensembl:ENSG00000100426(gene)|ensembl:ENST00000216268(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O75132|mint:MINT-8376338(identity)|uniprotkb:O75132(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:T1pqiOcpLeOA25QudngK1xk+xaA9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376476(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UQ13 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-993879|uniprotkb:O76063|uniprotkb:A8K9W8|uniprotkb:B3KR23|uniprotkb:Q5VZS8|uniprotkb:Q5VZS9|ensembl:ENSP00000358464 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:shoc2_human(display_long)|uniprotkb:Protein soc-2 homolog(gene name synonym)|uniprotkb:SHOC2(gene name)|psi-mi:SHOC2(display_short)|uniprotkb:KIAA0862(gene name synonym)|uniprotkb:Protein sur-8 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_031399.2|refseq:NP_001311265.1|refseq:NP_001311266.1|refseq:NP_001255968.1|refseq:XP_016872191.1|refseq:XP_016872192.1|refseq:XP_016872193.1|ensembl:ENSG00000108061(gene)|ensembl:ENST00000369452(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027036|interpro:IPR032675|mint:Q9UQ13|reactome:R-HSA-5673000|reactome:R-HSA-9660537|mint:MINT-8376470(identity)|uniprotkb:Q9UQ13(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:0RkCETF3NG59IZjnJevXVYkzBJU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P16219 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-3904404|uniprotkb:P78331|ensembl:ENSP00000242592 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:acads_human(display_long)|uniprotkb:ACADS(gene name)|psi-mi:ACADS(display_short)|uniprotkb:Butyryl-CoA dehydrogenase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_000008.1|refseq:NP_001289483.1|ensembl:ENSG00000122971(gene)|ensembl:ENST00000242592(transcript)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0004085"(butyryl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0046359"(butyrate catabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|rcsb pdb:2VIG|reactome:R-HSA-77350|reactome:R-HSA-77352|mint:MINT-8376304(identity)|uniprotkb:P16219(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:2c8OlkgpeqjWij0KxpQEiD3bOeE9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q00839 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N|mint:MINT-8376284(identity)|uniprotkb:Q00839(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P62987 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-357304|ensembl:ENSP00000388107|ensembl:ENSP00000396910|ensembl:ENSP00000470419|ensembl:ENSP00000470507|ensembl:ENSP00000471062|ensembl:ENSP00000471464|ensembl:ENSP00000471622|ensembl:ENSP00000472264|ensembl:ENSP00000472545|ensembl:ENSP00000473048|uniprotkb:P14793|uniprotkb:Q9BX98|uniprotkb:Q9UPK7|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rl40_human(display_long)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:CEP52(gene name synonym)|uniprotkb:Ubiquitin A-52 residue ribosomal protein fusion product 1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000221983(gene)|ensembl:ENST00000430157(transcript)|ensembl:ENST00000442744(transcript)|ensembl:ENST00000595158(transcript)|rcsb pdb:2MBH|rcsb pdb:2MJB|rcsb pdb:2MUR|ensembl:ENST00000595683(transcript)|ensembl:ENST00000596273(transcript)|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBD|ensembl:ENST00000596304(transcript)|rcsb pdb:2NBE|rcsb pdb:2RSU|rcsb pdb:4HJK|ensembl:ENST00000597451(transcript)|ensembl:ENST00000598780(transcript)|rcsb pdb:4JIO|rcsb pdb:4P4H|rcsb pdb:4PIG|ensembl:ENST00000599551(transcript)|ensembl:ENST00000599595(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:4PIH|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017085"(response to insecticide)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038587|mint:P62987|rcsb pdb:2LJ5|rcsb pdb:4PIJ|rcsb pdb:4RF0|rcsb pdb:4S1Z|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XKL|rcsb pdb:5AJ0|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5HPK|rcsb pdb:5HPL|rcsb pdb:5HPS|rcsb pdb:5HPT|rcsb pdb:5J26|rcsb pdb:5J8P|rcsb pdb:5JBV|rcsb pdb:5JBY|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:4RF1|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7AY1|rcsb pdb:7BHP|rcsb pdb:7M3Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|rcsb pdb:6Z6N|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-69231|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|refseq:NP_001029102.1|refseq:NP_003324.1|refseq:NP_001307947.1|refseq:NP_001307948.1|refseq:NP_001307949.1|refseq:NP_001307946.1|mint:MINT-8376238(identity)|uniprotkb:P62987(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:x9O/Pbww4D28M1+hIj+p0xrUXgU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q8WYP5 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-396018|uniprotkb:Q7Z4E3|uniprotkb:Q8IZA4|uniprotkb:Q96EH9|uniprotkb:Q9Y4Q6|uniprotkb:A6NGM0|uniprotkb:A8MSG9|uniprotkb:A8MZ86|ensembl:ENSP00000497061 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:elys_human(display_long)|uniprotkb:Protein MEL-28(gene name synonym)|uniprotkb:Putative AT-hook-containing transcription factor 1(gene name synonym)|uniprotkb:AHCTF1(gene name)|psi-mi:AHCTF1(display_short)|uniprotkb:Embryonic large molecule derived from yolk sac(gene name synonym)|uniprotkb:ELYS(gene name synonym)|uniprotkb:TMBS62(gene name synonym)|uniprotkb:MSTP108(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_056261.4|refseq:XP_006711821.1|refseq:NP_001310271.1|ensembl:ENSG00000153207(gene)|ensembl:ENST00000648844(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR025151|interpro:IPR032040|mint:Q8WYP5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|mint:MINT-8376572(identity)|uniprotkb:Q8WYP5(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ydOhjwcpt7Vl1X/urbAgH7EQrtE9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q8N1F7 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1042703|uniprotkb:Q14705|uniprotkb:B3KPQ8|ensembl:ENSP00000310668 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nup93_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short)|uniprotkb:KIAA0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_055484.3|refseq:NP_001229724.1|refseq:NP_001229725.1|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8N1F7|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|ensembl:ENSG00000102900(gene)|reactome:R-HSA-168271|ensembl:ENST00000308159(transcript)|go:"GO:0005635"(nuclear envelope)|reactome:R-HSA-168276|go:"GO:0005643"(nuclear pore)|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-191859|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005256320.1|dip:DIP-44020N|mint:MINT-8376142(identity)|uniprotkb:Q8N1F7(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:pkk5pooUC4yQShpqjiwNLddfy149606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q75T13 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1055128|uniprotkb:Q4G0R8|uniprotkb:Q4ZG47|uniprotkb:Q53SM0|uniprotkb:Q6AW92|uniprotkb:Q6UWV4|uniprotkb:Q9HA24|ensembl:ENSP00000346809 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:pgap1_human(display_long)|uniprotkb:Post-GPI attachment to proteins factor 1(gene name synonym)|uniprotkb:PGAP1(gene name)|psi-mi:PGAP1(display_short)|uniprotkb:UNQ3024/PRO9822(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001308028.1|refseq:NP_001308029.1|refseq:NP_079265.2|ensembl:ENSG00000197121(gene)|ensembl:ENST00000354764(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006505"(GPI anchor metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0021871"(forebrain regionalization)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0050185"(phosphatidylinositol deacylase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR012908(PGAP1-like)|interpro:IPR029058|interpro:IPR039529|mint:Q75T13|reactome:R-HSA-162791|refseq:XP_016860481.1|refseq:XP_016860482.1|mint:MINT-8376118(identity)|uniprotkb:Q75T13(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:mOh9dmfjLrZWaalO2QnERu+HPw49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376234(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P09923 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1052631|uniprotkb:Q53S80|uniprotkb:Q9UBV5|uniprotkb:Q9UCL2|uniprotkb:B2R7Y4|ensembl:ENSP00000295463 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ppbi_human(display_long)|uniprotkb:ALPI(gene name)|psi-mi:ALPI(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001622.2|ensembl:ENSG00000163295(gene)|ensembl:ENST00000295463(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002020"(protease binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|reactome:R-HSA-1483166|reactome:R-HSA-163125|reactome:R-HSA-8935690|mint:MINT-8376468(identity)|uniprotkb:P09923(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:RVz6SrTgIp87b+FLyMYQuoQDsI49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P28370 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2822460|uniprotkb:Q5JV41|uniprotkb:Q5JV42|ensembl:ENSP00000360163 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:smca1_human(display_long)|uniprotkb:SMARCA1(gene name)|psi-mi:SMARCA1(display_short)|uniprotkb:SNF2L(gene name synonym)|uniprotkb:SNF2L1(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA1(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit SNF2L(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_003060.2|refseq:NP_001269804.1|refseq:XP_006724845.1|refseq:XP_016885239.1|refseq:XP_005262518.1|dip:DIP-57685N|ensembl:ENSG00000102038(gene)|ensembl:ENST00000371122(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0090537"(CERF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044755|mint:P28370|mint:MINT-8376370(identity)|uniprotkb:P28370(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:BBDJMLUdqadz6iXLKjLJto+XF5s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q75T13 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1055128|uniprotkb:Q4G0R8|uniprotkb:Q4ZG47|uniprotkb:Q53SM0|uniprotkb:Q6AW92|uniprotkb:Q6UWV4|uniprotkb:Q9HA24|ensembl:ENSP00000346809 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:pgap1_human(display_long)|uniprotkb:Post-GPI attachment to proteins factor 1(gene name synonym)|uniprotkb:PGAP1(gene name)|psi-mi:PGAP1(display_short)|uniprotkb:UNQ3024/PRO9822(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001308028.1|refseq:NP_001308029.1|refseq:NP_079265.2|ensembl:ENSG00000197121(gene)|ensembl:ENST00000354764(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006505"(GPI anchor metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0021871"(forebrain regionalization)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0050185"(phosphatidylinositol deacylase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR012908(PGAP1-like)|interpro:IPR029058|interpro:IPR039529|mint:Q75T13|reactome:R-HSA-162791|refseq:XP_016860481.1|refseq:XP_016860482.1|mint:MINT-8376240(identity)|uniprotkb:Q75T13(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:mOh9dmfjLrZWaalO2QnERu+HPw49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376480(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P11166 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-717153|uniprotkb:A8K9S6|uniprotkb:O75535|uniprotkb:Q147X2|uniprotkb:B2R620|uniprotkb:D3DPX0|uniprotkb:Q0P512|ensembl:ENSP00000416293 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:gtr1_human(display_long)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)|uniprotkb:HepG2 glucose transporter(gene name synonym)|uniprotkb:SLC2A1(gene name)|psi-mi:SLC2A1(display_short)|uniprotkb:GLUT1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_006507.2|ensembl:ENSG00000117394(gene)|ensembl:ENST00000426263(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0072562"(blood microparticle)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11166|rcsb pdb:1SUK|rcsb pdb:4PYP|rcsb pdb:5EQG|rcsb pdb:5EQH|rcsb pdb:5EQI|rcsb pdb:6THA|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-422356|reactome:R-HSA-5619043|reactome:R-HSA-5653890|dip:DIP-23N|mint:MINT-8376486(identity)|uniprotkb:P11166(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:72DLUG1CFkqcf92goIZBZ4+zuls9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:O43823 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1237481|ensembl:ENSP00000269701 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:akap8_human(display_long)|uniprotkb:AKAP8(gene name)|psi-mi:AKAP8(display_short)|uniprotkb:AKAP95(gene name synonym)|uniprotkb:A-kinase anchor protein 95 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_005849.1|dip:DIP-38194N|ensembl:ENSG00000105127(gene)|ensembl:ENST00000269701(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045087"(innate immune response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:O43823|go:"GO:0051059"(NF-kappaB binding)|mint:MINT-8376178(identity)|uniprotkb:O43823(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:VtRlGSvkRqrzAcnq2Fj6fToZifY9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12236 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2|mint:MINT-8376402(identity)|uniprotkb:P12236(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P54098 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-852624|uniprotkb:Q8NFM2|uniprotkb:Q92515|ensembl:ENSP00000268124|ensembl:ENSP00000399851 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:dpog1_human(display_long)|uniprotkb:Mitochondrial DNA polymerase catalytic subunit(gene name synonym)|uniprotkb:PolG-alpha(gene name synonym)|uniprotkb:POLG(gene name)|psi-mi:POLG(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:POLG1(gene name synonym)|uniprotkb:POLGA(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001119603.1|refseq:NP_002684.1|ensembl:ENSG00000140521(gene)|ensembl:ENST00000268124(transcript)|ensembl:ENST00000442287(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0007568"(aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043195"(terminal bouton)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071333"(cellular response to glucose stimulus)|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR002297(DNA-directed DNA-polymerase, family A, mitochondria)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR019760|interpro:IPR041336|interpro:IPR043502|mint:P54098|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53|mint:MINT-8376366(identity)|uniprotkb:P54098(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:Gt8NCLdg0R/XLyFsovnrnLrzb/A9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376156(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376498(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376256(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P08047 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-298336|uniprotkb:Q86TN8|uniprotkb:Q9H3Q5|uniprotkb:Q9NR51|uniprotkb:Q9NY21|uniprotkb:Q9NYE7|intact:EBI-28977878|ensembl:ENSP00000329357|uniprotkb:E4Z9M7|uniprotkb:G5E9M8 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:sp1_human(display_long)|uniprotkb:SP1(gene name)|psi-mi:SP1(display_short)|uniprotkb:TSFP1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_003100.1|refseq:NP_612482.2|ensembl:ENSG00000185591(gene)|ensembl:ENST00000327443(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1904828"(positive regulation of hydrogen sulfide biosynthetic process)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P08047|rcsb pdb:1SP1|rcsb pdb:1SP2|rcsb pdb:1VA1|rcsb pdb:1VA2|rcsb pdb:1VA3|rcsb pdb:6PV0|rcsb pdb:6PV1|rcsb pdb:6PV2|rcsb pdb:6PV3|rcsb pdb:6UCO|rcsb pdb:6UCP|reactome:R-HSA-1989781|reactome:R-HSA-2173796|reactome:R-HSA-2426168|reactome:R-HSA-2559585|reactome:R-HSA-6807505|reactome:R-HSA-9018519|ensembl:ENSP00000329357|ensembl:ENST00000426431|ensembl:ENSP00000404263|refseq:NP_001238754.1|refseq:XP_011536998.1|dip:DIP-36N|mint:MINT-8376206(identity)|uniprotkb:P08047(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:mrIGsFyZTBVulhjVjVxNjFnTm5c9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376094(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q14191 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-368417|uniprotkb:A1KYY9|ensembl:ENSP00000298139 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:wrn_human(display_long)|uniprotkb:WRN(gene name)|psi-mi:WRN(display_short)|uniprotkb:RECQ3(gene name synonym)|uniprotkb:RECQL2(gene name synonym)|uniprotkb:Exonuclease WRN(gene name synonym)|uniprotkb:RecQ protein-like 2(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_000544.2|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0061849"(telomeric G-quadruplex DNA binding)|go:"GO:0070337"(3'-flap-structured DNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:0098530"(positive regulation of strand invasion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR027417|interpro:IPR029491|interpro:IPR032284|interpro:IPR036388|interpro:IPR036390|interpro:IPR036397|mint:Q14191|rcsb pdb:2AXL|rcsb pdb:2DGZ|rcsb pdb:2E1E|rcsb pdb:2E1F|rcsb pdb:2FBT|rcsb pdb:2FBV|rcsb pdb:2FBX|go:"GO:0061749"(forked DNA-dependent helicase activity)|rcsb pdb:2FBY|rcsb pdb:3AAF|rcsb pdb:6TYV|rcsb pdb:6YHR|reactome:R-HSA-174414|reactome:R-HSA-174437|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|rcsb pdb:2FC0|ensembl:ENSG00000165392(gene)|ensembl:ENST00000298139(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007569"(cell aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010225"(response to UV-C)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005730"(nucleolus)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0005813"(centrosome)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|dip:DIP-31380N|mint:MINT-8376436(identity)|uniprotkb:Q14191(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:AKmM4xnux0/lA9uEzk7yvug/Wng9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12235 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N|mint:MINT-8376528(identity)|uniprotkb:P12235(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P11166 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-717153|uniprotkb:A8K9S6|uniprotkb:O75535|uniprotkb:Q147X2|uniprotkb:B2R620|uniprotkb:D3DPX0|uniprotkb:Q0P512|ensembl:ENSP00000416293 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:gtr1_human(display_long)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)|uniprotkb:HepG2 glucose transporter(gene name synonym)|uniprotkb:SLC2A1(gene name)|psi-mi:SLC2A1(display_short)|uniprotkb:GLUT1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_006507.2|ensembl:ENSG00000117394(gene)|ensembl:ENST00000426263(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0072562"(blood microparticle)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11166|rcsb pdb:1SUK|rcsb pdb:4PYP|rcsb pdb:5EQG|rcsb pdb:5EQH|rcsb pdb:5EQI|rcsb pdb:6THA|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-422356|reactome:R-HSA-5619043|reactome:R-HSA-5653890|dip:DIP-23N|mint:MINT-8376550(identity)|uniprotkb:P11166(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:72DLUG1CFkqcf92goIZBZ4+zuls9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q00325 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325|mint:MINT-8376510(identity)|uniprotkb:Q00325(original identifier) go:"GO:0005634"(nucleus) - crc64:78714C85931B22D5 figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q75T13 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1055128|uniprotkb:Q4G0R8|uniprotkb:Q4ZG47|uniprotkb:Q53SM0|uniprotkb:Q6AW92|uniprotkb:Q6UWV4|uniprotkb:Q9HA24|ensembl:ENSP00000346809 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:pgap1_human(display_long)|uniprotkb:Post-GPI attachment to proteins factor 1(gene name synonym)|uniprotkb:PGAP1(gene name)|psi-mi:PGAP1(display_short)|uniprotkb:UNQ3024/PRO9822(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001308028.1|refseq:NP_001308029.1|refseq:NP_079265.2|ensembl:ENSG00000197121(gene)|ensembl:ENST00000354764(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006505"(GPI anchor metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0021871"(forebrain regionalization)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0050185"(phosphatidylinositol deacylase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR012908(PGAP1-like)|interpro:IPR029058|interpro:IPR039529|mint:Q75T13|reactome:R-HSA-162791|refseq:XP_016860481.1|refseq:XP_016860482.1|mint:MINT-8376440(identity)|uniprotkb:Q75T13(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:mOh9dmfjLrZWaalO2QnERu+HPw49606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q71UM5 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|mint:MINT-8376576(identity)|uniprotkb:Q71UM5(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q8NF50 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2548605|uniprotkb:B7ZLP0|uniprotkb:E9PH09|ensembl:ENSP00000394888|uniprotkb:A2A350|uniprotkb:A2BDF2|uniprotkb:A4FU78|uniprotkb:Q3MV16|uniprotkb:Q5JPJ1|uniprotkb:Q8TEP1|uniprotkb:Q8WUY2|uniprotkb:Q9BYJ5|uniprotkb:Q9H1Q2|uniprotkb:Q9H1Q3|uniprotkb:Q9H308|uniprotkb:Q9H7P2|intact:EBI-11070681 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:dock8_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_011516347.1|refseq:XP_011516349.1|ensembl:ENSG00000107099(gene)|ensembl:ENST00000432829(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061485"(memory T cell proliferation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-983231|refseq:XP_011516350.1|refseq:NP_001177387.1|refseq:NP_001180465.1|refseq:NP_982272.2|refseq:XP_016870662.1|mint:MINT-8376220(identity)|uniprotkb:Q8NF50(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:4ENO+3IOKfCUicfg8fxFQbwf4fg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376452(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UBX3 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0071422"(succinate transmembrane transport)|ensembl:ENSG00000183048(gene)|ensembl:ENST00000350690(transcript)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006811"(ion transport)|go:"GO:0006835"(dicarboxylic acid transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|reactome:R-HSA-70263|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643|mint:MINT-8376542(identity)|uniprotkb:Q9UBX3(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P11166 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-717153|uniprotkb:A8K9S6|uniprotkb:O75535|uniprotkb:Q147X2|uniprotkb:B2R620|uniprotkb:D3DPX0|uniprotkb:Q0P512|ensembl:ENSP00000416293 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:gtr1_human(display_long)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)|uniprotkb:HepG2 glucose transporter(gene name synonym)|uniprotkb:SLC2A1(gene name)|psi-mi:SLC2A1(display_short)|uniprotkb:GLUT1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_006507.2|ensembl:ENSG00000117394(gene)|ensembl:ENST00000426263(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0072562"(blood microparticle)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11166|rcsb pdb:1SUK|rcsb pdb:4PYP|rcsb pdb:5EQG|rcsb pdb:5EQH|rcsb pdb:5EQI|rcsb pdb:6THA|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-422356|reactome:R-HSA-5619043|reactome:R-HSA-5653890|dip:DIP-23N|mint:MINT-8376516(identity)|uniprotkb:P11166(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:72DLUG1CFkqcf92goIZBZ4+zuls9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376128(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q16891 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N|mint:MINT-8376134(identity)|uniprotkb:Q16891(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P13010 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|mint:MINT-8376570(identity)|uniprotkb:P13010(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12235 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N|mint:MINT-8376506(identity)|uniprotkb:P12235(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P02768 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-714423|ensembl:ENSP00000295897|uniprotkb:Q645G4|uniprotkb:O95574|uniprotkb:P04277|uniprotkb:Q13140|uniprotkb:Q68DN5|uniprotkb:Q6UXK4|uniprotkb:Q86YG0|uniprotkb:Q9P157|uniprotkb:Q9P1I7|uniprotkb:Q9UHS3|uniprotkb:Q9UJZ0|intact:EBI-7301844|intact:MINT-1161169|uniprotkb:E7ESS9|uniprotkb:Q8IUK7 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:albu_human(display_long)|uniprotkb:GIG42(orf name)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:PRO0903(orf name)|uniprotkb:PRO1708(orf name)|uniprotkb:PRO2044(orf name)|uniprotkb:PRO2619(orf name)|uniprotkb:PRO2675(orf name)|uniprotkb:UNQ696/PRO1341(orf name)|uniprotkb:GIG20(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000163631(gene)|ensembl:ENST00000295897(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:1E78|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051087"(chaperone binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P02768|rcsb pdb:1AO6|rcsb pdb:1BJ5|rcsb pdb:1BKE|rcsb pdb:1BM0|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|rcsb pdb:6XV0|rcsb pdb:6YG9|rcsb pdb:6ZL1|rcsb pdb:7A9C|rcsb pdb:7AAE|rcsb pdb:7AAI|rcsb pdb:7D6J|rcsb pdb:7JWN|reactome:R-HSA-114608|reactome:R-HSA-159418|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2168880|reactome:R-HSA-381426|reactome:R-HSA-879518|reactome:R-HSA-8957275|reactome:R-HSA-8964058|reactome:R-HSA-9707564|rcsb pdb:6WUW|rcsb pdb:1E7B|rcsb pdb:1E7C|rcsb pdb:1E7E|rcsb pdb:1E7F|rcsb pdb:1E7G|rcsb pdb:1E7H|rcsb pdb:1E7I|rcsb pdb:1GNI|rcsb pdb:1GNJ|rcsb pdb:1H9Z|rcsb pdb:1HA2|rcsb pdb:1HK1|rcsb pdb:1HK2|rcsb pdb:1HK3|rcsb pdb:1HK4|rcsb pdb:1HK5|rcsb pdb:1N5U|rcsb pdb:1O9X|rcsb pdb:1TF0|rcsb pdb:1UOR|rcsb pdb:1YSX|rcsb pdb:2BX8|rcsb pdb:2BXA|rcsb pdb:2BXB|rcsb pdb:2BXC|rcsb pdb:2BXD|rcsb pdb:1E7A|rcsb pdb:2BXE|rcsb pdb:2BXF|rcsb pdb:2BXG|rcsb pdb:2BXH|rcsb pdb:2BXI|rcsb pdb:2BXK|rcsb pdb:2BXL|rcsb pdb:2BXM|rcsb pdb:2BXN|rcsb pdb:2BXO|rcsb pdb:2BXP|rcsb pdb:2BXQ|rcsb pdb:2ESG|rcsb pdb:2I2Z|rcsb pdb:2I30|rcsb pdb:2N0X|rcsb pdb:2VDB|rcsb pdb:2VUE|rcsb pdb:2VUF|rcsb pdb:2XSI|rcsb pdb:2XVQ|rcsb pdb:2XVU|rcsb pdb:2XVV|rcsb pdb:2XVW|rcsb pdb:2XW0|rcsb pdb:2XW1|rcsb pdb:2YDF|rcsb pdb:3A73|rcsb pdb:3B9L|rcsb pdb:3B9M|rcsb pdb:3CX9|rcsb pdb:3JQZ|rcsb pdb:3JRY|rcsb pdb:3LU6|rcsb pdb:4HGM|rcsb pdb:4IW1|rcsb pdb:4IW2|rcsb pdb:4K2C|rcsb pdb:4K71|rcsb pdb:4L8U|rcsb pdb:4L9K|rcsb pdb:4L9Q|rcsb pdb:4LA0|rcsb pdb:4LB2|rcsb pdb:4LB9|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4S1Y|rcsb pdb:4Z69|rcsb pdb:5FUO|rcsb pdb:5GIX|rcsb pdb:5GIY|rcsb pdb:5ID7|rcsb pdb:5IFO|rcsb pdb:5IJF|rcsb pdb:5UJB|rcsb pdb:5VNW|rcsb pdb:5X52|rcsb pdb:5YB1|rcsb pdb:5YOQ|rcsb pdb:5Z0B|rcsb pdb:6A7P|rcsb pdb:6EZQ|rcsb pdb:6HSC|rcsb pdb:6JE7|rcsb pdb:6L4K|rcsb pdb:6M4R|rcsb pdb:3LU7|rcsb pdb:3LU8|rcsb pdb:3SQJ|rcsb pdb:3TDL|rcsb pdb:3UIV|rcsb pdb:4BKE|rcsb pdb:4E99|rcsb pdb:4EMX|rcsb pdb:4G03|rcsb pdb:4G04|rcsb pdb:4HGK|rcsb pdb:6M58|rcsb pdb:6M5D|rcsb pdb:6M5E|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R7S|refseq:NP_000468.1|dip:DIP-29902N|mint:MINT-8376420(identity)|uniprotkb:P02768(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:kjtn5mBsCZz/NRkcyW5k3ZWeJBU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376346(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P08047 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-298336|uniprotkb:Q86TN8|uniprotkb:Q9H3Q5|uniprotkb:Q9NR51|uniprotkb:Q9NY21|uniprotkb:Q9NYE7|intact:EBI-28977878|ensembl:ENSP00000329357|uniprotkb:E4Z9M7|uniprotkb:G5E9M8 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:sp1_human(display_long)|uniprotkb:SP1(gene name)|psi-mi:SP1(display_short)|uniprotkb:TSFP1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_003100.1|refseq:NP_612482.2|ensembl:ENSG00000185591(gene)|ensembl:ENST00000327443(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1904828"(positive regulation of hydrogen sulfide biosynthetic process)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P08047|rcsb pdb:1SP1|rcsb pdb:1SP2|rcsb pdb:1VA1|rcsb pdb:1VA2|rcsb pdb:1VA3|rcsb pdb:6PV0|rcsb pdb:6PV1|rcsb pdb:6PV2|rcsb pdb:6PV3|rcsb pdb:6UCO|rcsb pdb:6UCP|reactome:R-HSA-1989781|reactome:R-HSA-2173796|reactome:R-HSA-2426168|reactome:R-HSA-2559585|reactome:R-HSA-6807505|reactome:R-HSA-9018519|ensembl:ENSP00000329357|ensembl:ENST00000426431|ensembl:ENSP00000404263|refseq:NP_001238754.1|refseq:XP_011536998.1|dip:DIP-36N|mint:MINT-8376184(identity)|uniprotkb:P08047(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:mrIGsFyZTBVulhjVjVxNjFnTm5c9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q8TAT6 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1994109|uniprotkb:Q8N3J1|uniprotkb:Q9H8V2|uniprotkb:Q9H964|uniprotkb:Q9NWR5|uniprotkb:Q9P229|ensembl:ENSP00000331487 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:npl4_human(display_long)|uniprotkb:NPLOC4(gene name)|psi-mi:NPLOC4(display_short)|uniprotkb:KIAA1499(gene name synonym)|uniprotkb:NPL4(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_011523281.1|refseq:NP_060391.2|dip:DIP-44059N|ensembl:ENSG00000182446(gene)|ensembl:ENST00000331134(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0036501"(UFD1-NPL4 complex)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR007716(NPL4, zinc-binding putative)|interpro:IPR007717(NPL4)|interpro:IPR016563(Polyubiquitin-tagged protein recognition complex, Npl4 component)|interpro:IPR024682|interpro:IPR029071|interpro:IPR036443|interpro:IPR037518|mint:Q8TAT6|reactome:R-HSA-110320|mint:MINT-8376474(identity)|uniprotkb:Q8TAT6(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:GXRNmG7yqEf5aFMo7yPDih93yfk9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376534(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P57088 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1048629|uniprotkb:Q9H953|uniprotkb:B3KSS8|ensembl:ENSP00000422473|ensembl:ENSP00000427006|ensembl:ENSP00000441455 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:tmm33_human(display_long)|uniprotkb:Protein DB83(gene name synonym)|uniprotkb:TMEM33(gene name)|psi-mi:TMEM33(display_short)|uniprotkb:DB83(gene name synonym)|uniprotkb:SHINC-3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_060596.2|refseq:XP_005248173.1|refseq:XP_005248174.1|ensembl:ENSG00000109133(gene)|ensembl:ENST00000325094(transcript)|ensembl:ENST00000504986(transcript)|ensembl:ENST00000513702(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061024"(membrane organization)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR005344(Protein of unknown function UPF0121)|mint:P57088|mint:MINT-8376540(identity)|uniprotkb:P57088(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:FGc4/gpnYoRtlDJMxQWh5hXe5Ko9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376180(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P28331 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1|mint:MINT-8376080(identity)|uniprotkb:P28331(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q96RE9 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2826684|uniprotkb:B3KU35|uniprotkb:Q17RP3|uniprotkb:Q5H9N5|uniprotkb:A8MY91|uniprotkb:B4DU78|uniprotkb:Q06DQ3|ensembl:ENSP00000274599|uniprotkb:F5GWS1 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:zn300_human(display_long)|uniprotkb:ZNF300(gene name)|psi-mi:ZNF300(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001166302.1|refseq:NP_001166303.1|refseq:NP_443092.1|ensembl:ENSG00000145908(gene)|ensembl:ENST00000274599(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|mint:MINT-8376580(identity)|uniprotkb:Q96RE9(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:38iNcXE1eJW5dyX9zAN46FoXT589606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q14978 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-396155|uniprotkb:Q15030|intact:EBI-1055664|uniprotkb:Q9BUV3|uniprotkb:Q5VV70|ensembl:ENSP00000474710 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nolc1_human(display_long)|uniprotkb:NOLC1(gene name)|psi-mi:NOLC1(display_short)|uniprotkb:KIAA0035(gene name synonym)|uniprotkb:Nucleolar 130 kDa protein(gene name synonym)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Nucleolar phosphoprotein p130(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 13(gene name synonym)|uniprotkb:NS5ATP13(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_004732.2|refseq:NP_001271317.1|refseq:NP_001271318.1|ensembl:ENSG00000166197(gene)|ensembl:ENST00000605788(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0062064"(box C/D snoRNP complex binding)|go:"GO:0062065"(box H/ACA snoRNP complex binding)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|mint:Q14978|mint:MINT-8376332(identity)|uniprotkb:Q14978(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:G3ClYMfSSjWsDzkxtahX5lLRzzQ9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376430(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376202(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P02768 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-714423|ensembl:ENSP00000295897|uniprotkb:Q645G4|uniprotkb:O95574|uniprotkb:P04277|uniprotkb:Q13140|uniprotkb:Q68DN5|uniprotkb:Q6UXK4|uniprotkb:Q86YG0|uniprotkb:Q9P157|uniprotkb:Q9P1I7|uniprotkb:Q9UHS3|uniprotkb:Q9UJZ0|intact:EBI-7301844|intact:MINT-1161169|uniprotkb:E7ESS9|uniprotkb:Q8IUK7 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:albu_human(display_long)|uniprotkb:GIG42(orf name)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:PRO0903(orf name)|uniprotkb:PRO1708(orf name)|uniprotkb:PRO2044(orf name)|uniprotkb:PRO2619(orf name)|uniprotkb:PRO2675(orf name)|uniprotkb:UNQ696/PRO1341(orf name)|uniprotkb:GIG20(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000163631(gene)|ensembl:ENST00000295897(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:1E78|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051087"(chaperone binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P02768|rcsb pdb:1AO6|rcsb pdb:1BJ5|rcsb pdb:1BKE|rcsb pdb:1BM0|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|rcsb pdb:6XV0|rcsb pdb:6YG9|rcsb pdb:6ZL1|rcsb pdb:7A9C|rcsb pdb:7AAE|rcsb pdb:7AAI|rcsb pdb:7D6J|rcsb pdb:7JWN|reactome:R-HSA-114608|reactome:R-HSA-159418|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2168880|reactome:R-HSA-381426|reactome:R-HSA-879518|reactome:R-HSA-8957275|reactome:R-HSA-8964058|reactome:R-HSA-9707564|rcsb pdb:6WUW|rcsb pdb:1E7B|rcsb pdb:1E7C|rcsb pdb:1E7E|rcsb pdb:1E7F|rcsb pdb:1E7G|rcsb pdb:1E7H|rcsb pdb:1E7I|rcsb pdb:1GNI|rcsb pdb:1GNJ|rcsb pdb:1H9Z|rcsb pdb:1HA2|rcsb pdb:1HK1|rcsb pdb:1HK2|rcsb pdb:1HK3|rcsb pdb:1HK4|rcsb pdb:1HK5|rcsb pdb:1N5U|rcsb pdb:1O9X|rcsb pdb:1TF0|rcsb pdb:1UOR|rcsb pdb:1YSX|rcsb pdb:2BX8|rcsb pdb:2BXA|rcsb pdb:2BXB|rcsb pdb:2BXC|rcsb pdb:2BXD|rcsb pdb:1E7A|rcsb pdb:2BXE|rcsb pdb:2BXF|rcsb pdb:2BXG|rcsb pdb:2BXH|rcsb pdb:2BXI|rcsb pdb:2BXK|rcsb pdb:2BXL|rcsb pdb:2BXM|rcsb pdb:2BXN|rcsb pdb:2BXO|rcsb pdb:2BXP|rcsb pdb:2BXQ|rcsb pdb:2ESG|rcsb pdb:2I2Z|rcsb pdb:2I30|rcsb pdb:2N0X|rcsb pdb:2VDB|rcsb pdb:2VUE|rcsb pdb:2VUF|rcsb pdb:2XSI|rcsb pdb:2XVQ|rcsb pdb:2XVU|rcsb pdb:2XVV|rcsb pdb:2XVW|rcsb pdb:2XW0|rcsb pdb:2XW1|rcsb pdb:2YDF|rcsb pdb:3A73|rcsb pdb:3B9L|rcsb pdb:3B9M|rcsb pdb:3CX9|rcsb pdb:3JQZ|rcsb pdb:3JRY|rcsb pdb:3LU6|rcsb pdb:4HGM|rcsb pdb:4IW1|rcsb pdb:4IW2|rcsb pdb:4K2C|rcsb pdb:4K71|rcsb pdb:4L8U|rcsb pdb:4L9K|rcsb pdb:4L9Q|rcsb pdb:4LA0|rcsb pdb:4LB2|rcsb pdb:4LB9|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4S1Y|rcsb pdb:4Z69|rcsb pdb:5FUO|rcsb pdb:5GIX|rcsb pdb:5GIY|rcsb pdb:5ID7|rcsb pdb:5IFO|rcsb pdb:5IJF|rcsb pdb:5UJB|rcsb pdb:5VNW|rcsb pdb:5X52|rcsb pdb:5YB1|rcsb pdb:5YOQ|rcsb pdb:5Z0B|rcsb pdb:6A7P|rcsb pdb:6EZQ|rcsb pdb:6HSC|rcsb pdb:6JE7|rcsb pdb:6L4K|rcsb pdb:6M4R|rcsb pdb:3LU7|rcsb pdb:3LU8|rcsb pdb:3SQJ|rcsb pdb:3TDL|rcsb pdb:3UIV|rcsb pdb:4BKE|rcsb pdb:4E99|rcsb pdb:4EMX|rcsb pdb:4G03|rcsb pdb:4G04|rcsb pdb:4HGK|rcsb pdb:6M58|rcsb pdb:6M5D|rcsb pdb:6M5E|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R7S|refseq:NP_000468.1|dip:DIP-29902N|mint:MINT-8376296(identity)|uniprotkb:P02768(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:kjtn5mBsCZz/NRkcyW5k3ZWeJBU9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P29218 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-752410|uniprotkb:Q9UK71|uniprotkb:B4DLN3|uniprotkb:B2R733|uniprotkb:B7Z6Q4|uniprotkb:J3KQT7|ensembl:ENSP00000256108 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:impa1_human(display_long)|uniprotkb:"Inositol-1(or 4)-monophosphatase 1"(gene name synonym)|uniprotkb:Lithium-sensitive myo-inositol monophosphatase A1(gene name synonym)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short)|uniprotkb:IMPA(gene name synonym)|uniprotkb:D-galactose 1-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001138350.1|refseq:NP_001138351.1|refseq:NP_005527.1|ensembl:ENSG00000133731(gene)|ensembl:ENST00000256108(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031403"(lithium ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|go:"GO:0052834"(inositol monophosphate phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942|rcsb pdb:1AWB|rcsb pdb:1IMA|rcsb pdb:1IMB|rcsb pdb:1IMC|rcsb pdb:1IMD|rcsb pdb:1IME|rcsb pdb:1IMF|rcsb pdb:2HHM|rcsb pdb:4AS4|rcsb pdb:6GIU|rcsb pdb:6GJ0|rcsb pdb:6ZK0|reactome:R-HSA-1855183|mint:MINT-8376306(identity)|uniprotkb:P29218(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:o/z0MDOegfuflkvtDPoF12LHR/s9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P13010 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|mint:MINT-8376148(identity)|uniprotkb:P13010(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12235 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N|mint:MINT-8376354(identity)|uniprotkb:P12235(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P35527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-356382|uniprotkb:O00109|uniprotkb:Q0IJ47|uniprotkb:Q14665|ensembl:ENSP00000246662 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:k1c9_human(display_long)|uniprotkb:KRT9(gene name)|psi-mi:KRT9(display_short)|uniprotkb:Keratin-9(gene name synonym)|uniprotkb:Cytokeratin-9(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_000217.2|ensembl:ENSG00000171403(gene)|ensembl:ENST00000246662(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0043588"(skin development)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P35527|reactome:R-HSA-6805567|reactome:R-HSA-6809371|mint:MINT-8376062(identity)|uniprotkb:P35527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:m4EXfxbK2t1/EmI04YODKTJ02Zw9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P78527 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|mint:MINT-8376204(identity)|uniprotkb:P78527(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q8N1F7 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1042703|uniprotkb:Q14705|uniprotkb:B3KPQ8|ensembl:ENSP00000310668 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:nup93_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short)|uniprotkb:KIAA0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_055484.3|refseq:NP_001229724.1|refseq:NP_001229725.1|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8N1F7|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|ensembl:ENSG00000102900(gene)|reactome:R-HSA-168271|ensembl:ENST00000308159(transcript)|go:"GO:0005635"(nuclear envelope)|reactome:R-HSA-168276|go:"GO:0005643"(nuclear pore)|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-191859|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005256320.1|dip:DIP-44020N|mint:MINT-8376144(identity)|uniprotkb:Q8N1F7(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:pkk5pooUC4yQShpqjiwNLddfy149606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q96JM7 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|mint:MINT-8376154(identity)|uniprotkb:Q96JM7(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05556 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191|mint:MINT-8376122(identity)|uniprotkb:P05556(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q8WYP5 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-396018|uniprotkb:Q7Z4E3|uniprotkb:Q8IZA4|uniprotkb:Q96EH9|uniprotkb:Q9Y4Q6|uniprotkb:A6NGM0|uniprotkb:A8MSG9|uniprotkb:A8MZ86|ensembl:ENSP00000497061 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:elys_human(display_long)|uniprotkb:Protein MEL-28(gene name synonym)|uniprotkb:Putative AT-hook-containing transcription factor 1(gene name synonym)|uniprotkb:AHCTF1(gene name)|psi-mi:AHCTF1(display_short)|uniprotkb:Embryonic large molecule derived from yolk sac(gene name synonym)|uniprotkb:ELYS(gene name synonym)|uniprotkb:TMBS62(gene name synonym)|uniprotkb:MSTP108(orf name) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_056261.4|refseq:XP_006711821.1|refseq:NP_001310271.1|ensembl:ENSG00000153207(gene)|ensembl:ENST00000648844(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR025151|interpro:IPR032040|mint:Q8WYP5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|mint:MINT-8376336(identity)|uniprotkb:Q8WYP5(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:ydOhjwcpt7Vl1X/urbAgH7EQrtE9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376414(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P12236 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2|mint:MINT-8376058(identity)|uniprotkb:P12236(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:Q9UJV9 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-1046350|ensembl:ENSP00000330349|uniprotkb:Q96BK6|uniprotkb:Q96K05|uniprotkb:Q9NT96|uniprotkb:Q9NW04|uniprotkb:B2RDC8 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:ddx41_human(display_long)|uniprotkb:DEAD box protein 41(gene name synonym)|uniprotkb:DEAD box protein abstrakt homolog(gene name synonym)|uniprotkb:DDX41(gene name)|psi-mi:DDX41(display_short)|uniprotkb:ABS(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) ensembl:ENSG00000183258(gene)|ensembl:ENST00000330503(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044113|mint:Q9UJV9|rcsb pdb:2P6N|rcsb pdb:5GVS|rcsb pdb:5H1Y|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-3270619|rcsb pdb:5GVR|refseq:NP_057306.2|refseq:NP_001308661.1|refseq:NP_001308759.1|mint:MINT-8376344(identity)|uniprotkb:Q9UJV9(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:a3HNDsQBaXs/1q8ZXjkcMgEhPes9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:O00159 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-350423|uniprotkb:Q6NVJ7|intact:EBI-1045431|uniprotkb:Q86Y95|uniprotkb:Q4LE56|ensembl:ENSP00000496954 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:myo1c_human(display_long)|uniprotkb:MYO1C(gene name)|psi-mi:MYO1C(display_short)|uniprotkb:Myosin I beta(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0005829"(cytosol)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|refseq:NP_001074248.1|refseq:NP_001074419.1|refseq:NP_203693.3|ensembl:ENSG00000197879(gene)|ensembl:ENST00000648651(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O00159|rcsb pdb:4BYF|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-5250924|reactome:R-HSA-9662360|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|reactome:R-HSA-9662361|reactome:R-HSA-9664422|dip:DIP-33109N|mint:MINT-8376250(identity)|uniprotkb:O00159(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:g6wQN0OVKjd3T1kOebWFcqWNzNA9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O00716 uniprotkb:P05141 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0096"(pull down) von et al. (2012) doi:10.1038/emboj.2011.451|pubmed:22157815|imex:IM-20874|mint:MINT-8376005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7600105|mint:MINT-8376041|imex:IM-20874-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|mint:MINT-8376042(identity)|uniprotkb:O00716(original identifier) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N|mint:MINT-8376182(identity)|uniprotkb:P05141(original identifier) go:"GO:0005634"(nucleus) - - figure legend:ST1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/16 2018/09/18 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:D6B894A7446F5002|rigid:+SDBlMSQv3LhdJUddHHqL0WR9CM false glutathione s tranferase tag:?-?(MINT-8376044) - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)