#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-7598920	intact:EBI-7598931	intact:MINT-8382882	intact:MINT-8382874	psi-mi:h3n8q1_9entr(display_short)|psi-mi:EBI-7598920(display_long)|uniprotkb:HMPREF9694_04146(orf name)	psi-mi:h3n8q2_9entr(display_short)|psi-mi:EBI-7598931(display_long)|uniprotkb:HMPREF9694_04147(orf name)	psi-mi:"MI:0018"(two hybrid)	Cisneros et al. (2012)	doi:10.1038/emboj.2011.454|pubmed:22157749|imex:IM-17577|mint:MINT-8382755	taxid:1134687(klebsiella michiganensis)|taxid:1134687(klebsiella michiganensis)	taxid:1134687(klebsiella michiganensis)|taxid:1134687(klebsiella michiganensis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7598943|mint:MINT-8383617|imex:IM-17577-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:H3N8Q1(uniprot-removed-ac)|mint:MINT-8383620(identity)	uniprotkb:H3N8Q2(uniprot-removed-ac)|mint:MINT-8383619(identity)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:mint	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:mint	figure legend:f4a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/06/20	2014/10/16	rogid:UZbhOVZBUy+JUwVz9OCyDhsUbdg1134687	rogid:7j5+GwrNzlgF9pPmUZAZ7BGNz6g1134687	intact-crc:CC61459F68A5078E|rigid:tCfT8cop5nPpWoNhUpB+wpszKZs	false	fusion protein:?-?(MINT-8383626)	fusion protein:?-?(MINT-8383622)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P03069	uniprotkb:P03069	intact:EBI-7450|uniprotkb:P03068|uniprotkb:Q70D88|uniprotkb:Q70D91|uniprotkb:Q70D96|uniprotkb:Q70D99|uniprotkb:Q70DA0|uniprotkb:Q96UT3|uniprotkb:D3DLN9|ensemblfungi:YEL009C	intact:EBI-7450|uniprotkb:P03068|uniprotkb:Q70D88|uniprotkb:Q70D91|uniprotkb:Q70D96|uniprotkb:Q70D99|uniprotkb:Q70DA0|uniprotkb:Q96UT3|uniprotkb:D3DLN9|ensemblfungi:YEL009C	psi-mi:gcn4_yeast(display_long)|uniprotkb:ARG9(gene name synonym)|uniprotkb:GCN4(gene name)|psi-mi:GCN4(display_short)|uniprotkb:AAS3(gene name synonym)|uniprotkb:Amino acid biosynthesis regulatory protein(gene name synonym)|uniprotkb:AAS101(gene name synonym)|uniprotkb:General control protein GCN4(gene name synonym)|uniprotkb:YEL009C(locus name)	psi-mi:gcn4_yeast(display_long)|uniprotkb:ARG9(gene name synonym)|uniprotkb:GCN4(gene name)|psi-mi:GCN4(display_short)|uniprotkb:AAS3(gene name synonym)|uniprotkb:Amino acid biosynthesis regulatory protein(gene name synonym)|uniprotkb:AAS101(gene name synonym)|uniprotkb:General control protein GCN4(gene name synonym)|uniprotkb:YEL009C(locus name)	psi-mi:"MI:0018"(two hybrid)	Cisneros et al. (2012)	doi:10.1038/emboj.2011.454|pubmed:22157749|imex:IM-17577|mint:MINT-8382755	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7598960|mint:MINT-8383630|imex:IM-17577-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000735|refseq:NP_010907.3|mint:P03069|dip:DIP-591N|ensemblfungi:YEL009C(gene)|ensemblfungi:YEL009C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001080"(nitrogen catabolite activation of transcription from RNA polymerase II promoter)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061412"(positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:1CE9|rcsb pdb:1DGC|rcsb pdb:1ENV|rcsb pdb:1FAV|rcsb pdb:1FMH|rcsb pdb:1GCL|rcsb pdb:1GCM|rcsb pdb:1GK6|rcsb pdb:1GZL|rcsb pdb:1IHQ|rcsb pdb:1IJ0|rcsb pdb:1IJ1|rcsb pdb:1IJ2|rcsb pdb:1IJ3|rcsb pdb:1KQL|rcsb pdb:1LD4|rcsb pdb:1LLM|rcsb pdb:1NKN|rcsb pdb:1PIQ|rcsb pdb:1RB4|rcsb pdb:1RB5|rcsb pdb:1RB6|rcsb pdb:1SWI|rcsb pdb:1TMZ|rcsb pdb:1UNT|rcsb pdb:1UNU|rcsb pdb:1UNV|rcsb pdb:1UNW|rcsb pdb:1UNX|rcsb pdb:1UNY|rcsb pdb:1UNZ|rcsb pdb:1UO0|rcsb pdb:1UO1|rcsb pdb:1UO2|rcsb pdb:1UO3|rcsb pdb:1UO4|rcsb pdb:1UO5|rcsb pdb:1W5G|rcsb pdb:1W5H|rcsb pdb:1W5I|rcsb pdb:1W5J|rcsb pdb:1W5K|rcsb pdb:1W5L|rcsb pdb:1YSA|rcsb pdb:1ZII|rcsb pdb:1ZIJ|rcsb pdb:1ZIK|rcsb pdb:1ZIL|rcsb pdb:1ZIM|rcsb pdb:1ZTA|rcsb pdb:2AHP|rcsb pdb:2B1F|rcsb pdb:2B22|rcsb pdb:2BNI|rcsb pdb:2CCE|rcsb pdb:2CCF|rcsb pdb:2CCN|rcsb pdb:2D3E|rcsb pdb:2DGC|rcsb pdb:2EFR|rcsb pdb:2EFS|rcsb pdb:2G9J|rcsb pdb:2HY6|rcsb pdb:2IPZ|rcsb pdb:2K8X|rcsb pdb:2LPB|rcsb pdb:2N9B|rcsb pdb:2NRN|rcsb pdb:2O7H|rcsb pdb:2OVN|rcsb pdb:2VKY|rcsb pdb:2VNL|rcsb pdb:2WG5|rcsb pdb:2WG6|rcsb pdb:2WPY|rcsb pdb:2WPZ|rcsb pdb:2WQ0|rcsb pdb:2WQ1|rcsb pdb:2WQ2|rcsb pdb:2WQ3|rcsb pdb:2YNY|rcsb pdb:2YNZ|rcsb pdb:2YO0|rcsb pdb:2YO1|rcsb pdb:2YO2|rcsb pdb:2YO3|rcsb pdb:2Z5H|rcsb pdb:2Z5I|rcsb pdb:2ZTA|rcsb pdb:3AZD|rcsb pdb:3BAS|rcsb pdb:3BAT|rcsb pdb:3CK4|rcsb pdb:3CRP|rcsb pdb:3G9R|rcsb pdb:3GJP|rcsb pdb:3I1G|rcsb pdb:3I5C|rcsb pdb:3K7Z|rcsb pdb:3M48|rcsb pdb:3P8M|rcsb pdb:3ZMF|rcsb pdb:4C46|rcsb pdb:4DMD|rcsb pdb:4G2K|rcsb pdb:4HU5|rcsb pdb:4HU6|rcsb pdb:4NIZ|rcsb pdb:4NJ0|rcsb pdb:4NJ1|rcsb pdb:4NJ2|rcsb pdb:4OWI|rcsb pdb:4TL1|rcsb pdb:5APP|rcsb pdb:5APQ|rcsb pdb:5APS|rcsb pdb:5APT|rcsb pdb:5APU|rcsb pdb:5APV|rcsb pdb:5APW|rcsb pdb:5APX|rcsb pdb:5APY|rcsb pdb:5APZ|rcsb pdb:5IEW|rcsb pdb:5IIR|rcsb pdb:5IIV|rcsb pdb:5KHT|rcsb pdb:6E52|rcsb pdb:6E95|rcsb pdb:6H9M|rcsb pdb:6HN4|rcsb pdb:6HN5|rcsb pdb:6O2E|rcsb pdb:6O2F|rcsb pdb:6PSA|rcsb pdb:6UT2|rcsb pdb:6VWG|rcsb pdb:6VWH|rcsb pdb:6VWI|rcsb pdb:6VWJ|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450341|mint:MINT-8383636(identity)	sgd:S000000735|refseq:NP_010907.3|mint:P03069|dip:DIP-591N|ensemblfungi:YEL009C(gene)|ensemblfungi:YEL009C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001080"(nitrogen catabolite activation of transcription from RNA polymerase II promoter)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061412"(positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:1CE9|rcsb pdb:1DGC|rcsb pdb:1ENV|rcsb pdb:1FAV|rcsb pdb:1FMH|rcsb pdb:1GCL|rcsb pdb:1GCM|rcsb pdb:1GK6|rcsb pdb:1GZL|rcsb pdb:1IHQ|rcsb pdb:1IJ0|rcsb pdb:1IJ1|rcsb pdb:1IJ2|rcsb pdb:1IJ3|rcsb pdb:1KQL|rcsb pdb:1LD4|rcsb pdb:1LLM|rcsb pdb:1NKN|rcsb pdb:1PIQ|rcsb pdb:1RB4|rcsb pdb:1RB5|rcsb pdb:1RB6|rcsb pdb:1SWI|rcsb pdb:1TMZ|rcsb pdb:1UNT|rcsb pdb:1UNU|rcsb pdb:1UNV|rcsb pdb:1UNW|rcsb pdb:1UNX|rcsb pdb:1UNY|rcsb pdb:1UNZ|rcsb pdb:1UO0|rcsb pdb:1UO1|rcsb pdb:1UO2|rcsb pdb:1UO3|rcsb pdb:1UO4|rcsb pdb:1UO5|rcsb pdb:1W5G|rcsb pdb:1W5H|rcsb pdb:1W5I|rcsb pdb:1W5J|rcsb pdb:1W5K|rcsb pdb:1W5L|rcsb pdb:1YSA|rcsb pdb:1ZII|rcsb pdb:1ZIJ|rcsb pdb:1ZIK|rcsb pdb:1ZIL|rcsb pdb:1ZIM|rcsb pdb:1ZTA|rcsb pdb:2AHP|rcsb pdb:2B1F|rcsb pdb:2B22|rcsb pdb:2BNI|rcsb pdb:2CCE|rcsb pdb:2CCF|rcsb pdb:2CCN|rcsb pdb:2D3E|rcsb pdb:2DGC|rcsb pdb:2EFR|rcsb pdb:2EFS|rcsb pdb:2G9J|rcsb pdb:2HY6|rcsb pdb:2IPZ|rcsb pdb:2K8X|rcsb pdb:2LPB|rcsb pdb:2N9B|rcsb pdb:2NRN|rcsb pdb:2O7H|rcsb pdb:2OVN|rcsb pdb:2VKY|rcsb pdb:2VNL|rcsb pdb:2WG5|rcsb pdb:2WG6|rcsb pdb:2WPY|rcsb pdb:2WPZ|rcsb pdb:2WQ0|rcsb pdb:2WQ1|rcsb pdb:2WQ2|rcsb pdb:2WQ3|rcsb pdb:2YNY|rcsb pdb:2YNZ|rcsb pdb:2YO0|rcsb pdb:2YO1|rcsb pdb:2YO2|rcsb pdb:2YO3|rcsb pdb:2Z5H|rcsb pdb:2Z5I|rcsb pdb:2ZTA|rcsb pdb:3AZD|rcsb pdb:3BAS|rcsb pdb:3BAT|rcsb pdb:3CK4|rcsb pdb:3CRP|rcsb pdb:3G9R|rcsb pdb:3GJP|rcsb pdb:3I1G|rcsb pdb:3I5C|rcsb pdb:3K7Z|rcsb pdb:3M48|rcsb pdb:3P8M|rcsb pdb:3ZMF|rcsb pdb:4C46|rcsb pdb:4DMD|rcsb pdb:4G2K|rcsb pdb:4HU5|rcsb pdb:4HU6|rcsb pdb:4NIZ|rcsb pdb:4NJ0|rcsb pdb:4NJ1|rcsb pdb:4NJ2|rcsb pdb:4OWI|rcsb pdb:4TL1|rcsb pdb:5APP|rcsb pdb:5APQ|rcsb pdb:5APS|rcsb pdb:5APT|rcsb pdb:5APU|rcsb pdb:5APV|rcsb pdb:5APW|rcsb pdb:5APX|rcsb pdb:5APY|rcsb pdb:5APZ|rcsb pdb:5IEW|rcsb pdb:5IIR|rcsb pdb:5IIV|rcsb pdb:5KHT|rcsb pdb:6E52|rcsb pdb:6E95|rcsb pdb:6H9M|rcsb pdb:6HN4|rcsb pdb:6HN5|rcsb pdb:6O2E|rcsb pdb:6O2F|rcsb pdb:6PSA|rcsb pdb:6UT2|rcsb pdb:6VWG|rcsb pdb:6VWH|rcsb pdb:6VWI|rcsb pdb:6VWJ|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450341|mint:MINT-8383632(identity)	-	crc64:2ED1B8E35D509578	crc64:2ED1B8E35D509578	figure legend:f4a|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/06/20	2014/10/16	rogid:MFj9JcYccWKTayvnuaN95djsHd0559292	rogid:MFj9JcYccWKTayvnuaN95djsHd0559292	intact-crc:1D5E260839D6E469|rigid:q9aALwC1bPcZROqvbqKmvdK/TwY	false	fusion protein:?-?(MINT-8383637)|binding-associated region:?-?(MINT-8383646)	fusion protein:?-?(MINT-8383633)|binding-associated region:?-?(MINT-8383642)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-7598931	intact:EBI-7598996	intact:MINT-8382874	intact:MINT-8382884	psi-mi:h3n8q2_9entr(display_short)|psi-mi:EBI-7598931(display_long)|uniprotkb:HMPREF9694_04147(orf name)	psi-mi:h3n8q0_9entr(display_short)|psi-mi:EBI-7598996(display_long)|uniprotkb:HMPREF9694_04145(orf name)	psi-mi:"MI:0096"(pull down)	Cisneros et al. (2012)	doi:10.1038/emboj.2011.454|pubmed:22157749|imex:IM-17577|mint:MINT-8382755	taxid:1134687(klebsiella michiganensis)|taxid:1134687(klebsiella michiganensis)	taxid:1134687(klebsiella michiganensis)|taxid:1134687(klebsiella michiganensis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7599006|mint:MINT-8383658|imex:IM-17577-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:H3N8Q2(uniprot-removed-ac)|mint:MINT-8383660(identity)	uniprotkb:H3N8Q0(uniprot-removed-ac)|mint:MINT-8383664(identity)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:mint	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:mint	figure legend:f4f|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/06/20	2014/10/16	rogid:7j5+GwrNzlgF9pPmUZAZ7BGNz6g1134687	rogid:HfTuUNeqIjtyg4hRJEBxBCwdEEw1134687	intact-crc:BC8FEAA7B8096263|rigid:a2ufCY385eFNsx82mRD+xrhEIk4	false	-	his tag:?-?(MINT-8383665)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)