#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P79010	uniprotkb:O14156	intact:EBI-7593610|intact:MINT-4691869|ensemblfungi:"SPAC1296.02.1:pep"	intact:EBI-7593590|uniprotkb:Q9UR02|intact:MINT-4670968|ensemblfungi:"SPAC4A8.03c.1:pep"	psi-mi:cox4_schpo(display_long)|uniprotkb:cox4(gene name)|psi-mi:cox4(display_short)|uniprotkb:SPAC1296.02(orf name)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:pp2c4_schpo(display_long)|uniprotkb:ptc4(gene name)|psi-mi:ptc4(display_short)|uniprotkb:SPAC4A8.03c(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Di et al. (2012)	doi:10.1038/emboj.2011.438|pubmed:22139357|imex:IM-17562|mint:MINT-8374053	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593584|mint:MINT-8374382|imex:IM-17562-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|refseq:NP_593042.1|ensemblfungi:SPAC1296.02(gene)|ensemblfungi:SPAC1296.02.1(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0046872"(metal ion binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR036972|mint:MINT-8374385(identity)	interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|refseq:NP_593814.1|ensemblfungi:SPAC4A8.03c(gene)|ensemblfungi:SPAC4A8.03c.1(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0023052"(signaling)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0061191"(positive regulation of vacuole fusion, non-autophagic)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901098"(positive regulation of autophagosome maturation)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR036457|mint:MINT-8374384(identity)	go:"GO:0005739"(mitochondrion)	comment:mint	comment:mint|function:Has a role in the regulation of vacuole fusion	comment:mint|figure legend:f2d f2e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	-	2012/05/10	2014/10/16	rogid:ai0o0OsWqF4LEF2K38lCZ3JXL9s284812	rogid:Kyul2EchWERR1gJbaaz7tAHwKqc284812	intact-crc:1CD2E3D6C24B9536|rigid:0XfIhyOrQIM0uivM9I36vN8Ssuo	false	green fluorescent protein tag:?-?(MINT-8374392)	red fluorescent protein tag:?-?(MINT-8374388)	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P79010	uniprotkb:Q09892	intact:EBI-7593610|intact:MINT-4691869|ensemblfungi:"SPAC1296.02.1:pep"	intact:EBI-3648525|ensemblfungi:"SPAC24B11.06c.1:pep"	psi-mi:cox4_schpo(display_long)|uniprotkb:cox4(gene name)|psi-mi:cox4(display_short)|uniprotkb:SPAC1296.02(orf name)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:hog1_schpo(display_long)|uniprotkb:sty1(gene name)|psi-mi:sty1(display_short)|uniprotkb:hog1(gene name synonym)|uniprotkb:phh1(gene name synonym)|uniprotkb:spc1(gene name synonym)|uniprotkb:MAP kinase spc1(gene name synonym)|uniprotkb:SPAC24B11.06c(orf name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Di et al. (2012)	doi:10.1038/emboj.2011.438|pubmed:22139357|imex:IM-17562|mint:MINT-8374053	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593729|mint:MINT-8374400|imex:IM-17562-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|refseq:NP_593042.1|ensemblfungi:SPAC1296.02(gene)|ensemblfungi:SPAC1296.02.1(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0046872"(metal ion binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR036972|mint:MINT-8374407(identity)	interpro:IPR038783|refseq:NP_592843.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-168638|reactome:R-SPO-450341|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010515"(negative regulation of induction of conjugation with cellular fusion)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904789"(regulation of mitotic actomyosin contractile ring maintenance)|go:"GO:1990625"(negative regulation of cytoplasmic translational initiation in response to stress)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:0007231"(osmosensory signaling pathway)|ensemblfungi:SPAC24B11.06c(gene)|ensemblfungi:SPAC24B11.06c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|reactome:R-SPO-6798695|reactome:R-SPO-418592|reactome:R-SPO-432142|reactome:R-SPO-525793|reactome:R-SPO-198753|reactome:R-SPO-5668599|reactome:R-SPO-193648|reactome:R-SPO-2559580|reactome:R-SPO-2871796|reactome:R-SPO-450321|reactome:R-SPO-9007892|mint:MINT-8374416(identity)	go:"GO:0005739"(mitochondrion)	comment:mint	-	comment:mint|figure legend:f3d f3c sf4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/10	2014/10/16	rogid:ai0o0OsWqF4LEF2K38lCZ3JXL9s284812	rogid:kBCikrs/6vxOvBRFqt4X4Up1IS8284812	intact-crc:F749627425D78BAC|rigid:LyfCla4GET2PQpSpaCTWcSZqX4A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P79010	uniprotkb:Q09864	intact:EBI-7593610|intact:MINT-4691869|ensemblfungi:"SPAC1296.02.1:pep"	intact:EBI-7593707|uniprotkb:Q10285|intact:MINT-4695833|ensemblfungi:"SPAC12G12.04.1:pep"	psi-mi:cox4_schpo(display_long)|uniprotkb:cox4(gene name)|psi-mi:cox4(display_short)|uniprotkb:SPAC1296.02(orf name)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:hsp60_schpo(display_long)|uniprotkb:hsp60(gene name)|psi-mi:hsp60(display_short)|uniprotkb:mcp60(gene name synonym)|uniprotkb:SPAC12G12.04(orf name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Di et al. (2012)	doi:10.1038/emboj.2011.438|pubmed:22139357|imex:IM-17562|mint:MINT-8374053	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593729|mint:MINT-8374400|imex:IM-17562-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|refseq:NP_593042.1|ensemblfungi:SPAC1296.02(gene)|ensemblfungi:SPAC1296.02.1(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0046872"(metal ion binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR036972|mint:MINT-8374407(identity)	interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027410|reactome:R-SPO-1268020|refseq:NP_592894.1|interpro:IPR027413|interpro:IPR027409|ensemblfungi:SPAC12G12.04(gene)|ensemblfungi:SPAC12G12.04.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051087"(chaperone binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|mint:MINT-8374415(identity)	go:"GO:0005739"(mitochondrion)	comment:mint	comment:mint|function:May participate in assembly and/or disassembly of proteins imported into the mitochondrion. HSP60 are ATPases and have affinity for unfolded proteins	comment:mint|figure legend:f3d f3c sf4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/10	2014/10/16	rogid:ai0o0OsWqF4LEF2K38lCZ3JXL9s284812	rogid:5grD1cCK2XRdYS88QIenM3BIZMs284812	intact-crc:F749627425D78BAC|rigid:LyfCla4GET2PQpSpaCTWcSZqX4A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P79010	uniprotkb:O14156	intact:EBI-7593610|intact:MINT-4691869|ensemblfungi:"SPAC1296.02.1:pep"	intact:EBI-7593590|uniprotkb:Q9UR02|intact:MINT-4670968|ensemblfungi:"SPAC4A8.03c.1:pep"	psi-mi:cox4_schpo(display_long)|uniprotkb:cox4(gene name)|psi-mi:cox4(display_short)|uniprotkb:SPAC1296.02(orf name)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:pp2c4_schpo(display_long)|uniprotkb:ptc4(gene name)|psi-mi:ptc4(display_short)|uniprotkb:SPAC4A8.03c(orf name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Di et al. (2012)	doi:10.1038/emboj.2011.438|pubmed:22139357|imex:IM-17562|mint:MINT-8374053	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593729|mint:MINT-8374400|imex:IM-17562-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|refseq:NP_593042.1|ensemblfungi:SPAC1296.02(gene)|ensemblfungi:SPAC1296.02.1(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0046872"(metal ion binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR036972|mint:MINT-8374407(identity)	interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|refseq:NP_593814.1|ensemblfungi:SPAC4A8.03c(gene)|ensemblfungi:SPAC4A8.03c.1(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0023052"(signaling)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0061191"(positive regulation of vacuole fusion, non-autophagic)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901098"(positive regulation of autophagosome maturation)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR036457|mint:MINT-8374403(identity)	go:"GO:0005739"(mitochondrion)	comment:mint	comment:mint|function:Has a role in the regulation of vacuole fusion	comment:mint|figure legend:f3d f3c sf4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/10	2014/10/16	rogid:ai0o0OsWqF4LEF2K38lCZ3JXL9s284812	rogid:Kyul2EchWERR1gJbaaz7tAHwKqc284812	intact-crc:F749627425D78BAC|rigid:LyfCla4GET2PQpSpaCTWcSZqX4A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q09892	uniprotkb:Q09864	intact:EBI-3648525|ensemblfungi:"SPAC24B11.06c.1:pep"	intact:EBI-7593707|uniprotkb:Q10285|intact:MINT-4695833|ensemblfungi:"SPAC12G12.04.1:pep"	psi-mi:hog1_schpo(display_long)|uniprotkb:sty1(gene name)|psi-mi:sty1(display_short)|uniprotkb:hog1(gene name synonym)|uniprotkb:phh1(gene name synonym)|uniprotkb:spc1(gene name synonym)|uniprotkb:MAP kinase spc1(gene name synonym)|uniprotkb:SPAC24B11.06c(orf name)	psi-mi:hsp60_schpo(display_long)|uniprotkb:hsp60(gene name)|psi-mi:hsp60(display_short)|uniprotkb:mcp60(gene name synonym)|uniprotkb:SPAC12G12.04(orf name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Di et al. (2012)	doi:10.1038/emboj.2011.438|pubmed:22139357|imex:IM-17562|mint:MINT-8374053	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593767|mint:MINT-8374423|imex:IM-17562-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038783|refseq:NP_592843.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-168638|reactome:R-SPO-450341|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010515"(negative regulation of induction of conjugation with cellular fusion)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904789"(regulation of mitotic actomyosin contractile ring maintenance)|go:"GO:1990625"(negative regulation of cytoplasmic translational initiation in response to stress)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:0007231"(osmosensory signaling pathway)|ensemblfungi:SPAC24B11.06c(gene)|ensemblfungi:SPAC24B11.06c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|reactome:R-SPO-6798695|reactome:R-SPO-418592|reactome:R-SPO-432142|reactome:R-SPO-525793|reactome:R-SPO-198753|reactome:R-SPO-5668599|reactome:R-SPO-193648|reactome:R-SPO-2559580|reactome:R-SPO-2871796|reactome:R-SPO-450321|reactome:R-SPO-9007892|mint:MINT-8374432(identity)	interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027410|reactome:R-SPO-1268020|refseq:NP_592894.1|interpro:IPR027413|interpro:IPR027409|ensemblfungi:SPAC12G12.04(gene)|ensemblfungi:SPAC12G12.04.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051087"(chaperone binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|mint:MINT-8374430(identity)	go:"GO:0005739"(mitochondrion)	-	comment:mint|function:May participate in assembly and/or disassembly of proteins imported into the mitochondrion. HSP60 are ATPases and have affinity for unfolded proteins	comment:mint|figure legend:f3a f3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/10	2014/10/16	rogid:kBCikrs/6vxOvBRFqt4X4Up1IS8284812	rogid:5grD1cCK2XRdYS88QIenM3BIZMs284812	intact-crc:2FD338CA5CEE023F|rigid:7ncTe7hpzpu/JTl0UoX818uKmEI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q09892	uniprotkb:O14156	intact:EBI-3648525|ensemblfungi:"SPAC24B11.06c.1:pep"	intact:EBI-7593590|uniprotkb:Q9UR02|intact:MINT-4670968|ensemblfungi:"SPAC4A8.03c.1:pep"	psi-mi:hog1_schpo(display_long)|uniprotkb:sty1(gene name)|psi-mi:sty1(display_short)|uniprotkb:hog1(gene name synonym)|uniprotkb:phh1(gene name synonym)|uniprotkb:spc1(gene name synonym)|uniprotkb:MAP kinase spc1(gene name synonym)|uniprotkb:SPAC24B11.06c(orf name)	psi-mi:pp2c4_schpo(display_long)|uniprotkb:ptc4(gene name)|psi-mi:ptc4(display_short)|uniprotkb:SPAC4A8.03c(orf name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Di et al. (2012)	doi:10.1038/emboj.2011.438|pubmed:22139357|imex:IM-17562|mint:MINT-8374053	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593767|mint:MINT-8374423|imex:IM-17562-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038783|refseq:NP_592843.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-168638|reactome:R-SPO-450341|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010515"(negative regulation of induction of conjugation with cellular fusion)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904789"(regulation of mitotic actomyosin contractile ring maintenance)|go:"GO:1990625"(negative regulation of cytoplasmic translational initiation in response to stress)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:0007231"(osmosensory signaling pathway)|ensemblfungi:SPAC24B11.06c(gene)|ensemblfungi:SPAC24B11.06c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|reactome:R-SPO-6798695|reactome:R-SPO-418592|reactome:R-SPO-432142|reactome:R-SPO-525793|reactome:R-SPO-198753|reactome:R-SPO-5668599|reactome:R-SPO-193648|reactome:R-SPO-2559580|reactome:R-SPO-2871796|reactome:R-SPO-450321|reactome:R-SPO-9007892|mint:MINT-8374432(identity)	interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|refseq:NP_593814.1|ensemblfungi:SPAC4A8.03c(gene)|ensemblfungi:SPAC4A8.03c.1(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0023052"(signaling)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0061191"(positive regulation of vacuole fusion, non-autophagic)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901098"(positive regulation of autophagosome maturation)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR036457|mint:MINT-8374426(identity)	go:"GO:0005739"(mitochondrion)	-	comment:mint|function:Has a role in the regulation of vacuole fusion	comment:mint|figure legend:f3a f3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/10	2014/10/16	rogid:kBCikrs/6vxOvBRFqt4X4Up1IS8284812	rogid:Kyul2EchWERR1gJbaaz7tAHwKqc284812	intact-crc:2FD338CA5CEE023F|rigid:7ncTe7hpzpu/JTl0UoX818uKmEI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q09892	uniprotkb:O14156	intact:EBI-3648525|ensemblfungi:"SPAC24B11.06c.1:pep"	intact:EBI-7593590|uniprotkb:Q9UR02|intact:MINT-4670968|ensemblfungi:"SPAC4A8.03c.1:pep"	psi-mi:hog1_schpo(display_long)|uniprotkb:sty1(gene name)|psi-mi:sty1(display_short)|uniprotkb:hog1(gene name synonym)|uniprotkb:phh1(gene name synonym)|uniprotkb:spc1(gene name synonym)|uniprotkb:MAP kinase spc1(gene name synonym)|uniprotkb:SPAC24B11.06c(orf name)	psi-mi:pp2c4_schpo(display_long)|uniprotkb:ptc4(gene name)|psi-mi:ptc4(display_short)|uniprotkb:SPAC4A8.03c(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Di et al. (2012)	doi:10.1038/emboj.2011.438|pubmed:22139357|imex:IM-17562|mint:MINT-8374053	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593811|mint:MINT-8374442|imex:IM-17562-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038783|refseq:NP_592843.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-168638|reactome:R-SPO-450341|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010515"(negative regulation of induction of conjugation with cellular fusion)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904789"(regulation of mitotic actomyosin contractile ring maintenance)|go:"GO:1990625"(negative regulation of cytoplasmic translational initiation in response to stress)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:0007231"(osmosensory signaling pathway)|ensemblfungi:SPAC24B11.06c(gene)|ensemblfungi:SPAC24B11.06c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|reactome:R-SPO-6798695|reactome:R-SPO-418592|reactome:R-SPO-432142|reactome:R-SPO-525793|reactome:R-SPO-198753|reactome:R-SPO-5668599|reactome:R-SPO-193648|reactome:R-SPO-2559580|reactome:R-SPO-2871796|reactome:R-SPO-450321|reactome:R-SPO-9007892|mint:MINT-8374449(identity)	interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|refseq:NP_593814.1|ensemblfungi:SPAC4A8.03c(gene)|ensemblfungi:SPAC4A8.03c.1(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0023052"(signaling)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0061191"(positive regulation of vacuole fusion, non-autophagic)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901098"(positive regulation of autophagosome maturation)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR036457|mint:MINT-8374445(identity)	-	-	comment:mint|function:Has a role in the regulation of vacuole fusion	figure legend:f4a|comment:mint|comment:upon exposure to oxidative stress.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	-	2012/05/10	2014/10/16	rogid:kBCikrs/6vxOvBRFqt4X4Up1IS8284812	rogid:Kyul2EchWERR1gJbaaz7tAHwKqc284812	intact-crc:4771E4D8EB8CFE1F|rigid:0dDfSa6pNbWBM8T4v458ZUiPc+k	false	-	mutation disrupting interaction:8-8(MINT-8374491)|mutation disrupting interaction:10-10(MINT-8374493)|tag:?-?(MINT-8374486)|mutation disrupting interaction:27-27(MINT-8374495)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q09892	uniprotkb:O14156	intact:EBI-3648525|ensemblfungi:"SPAC24B11.06c.1:pep"	intact:EBI-7593590|uniprotkb:Q9UR02|intact:MINT-4670968|ensemblfungi:"SPAC4A8.03c.1:pep"	psi-mi:hog1_schpo(display_long)|uniprotkb:sty1(gene name)|psi-mi:sty1(display_short)|uniprotkb:hog1(gene name synonym)|uniprotkb:phh1(gene name synonym)|uniprotkb:spc1(gene name synonym)|uniprotkb:MAP kinase spc1(gene name synonym)|uniprotkb:SPAC24B11.06c(orf name)	psi-mi:pp2c4_schpo(display_long)|uniprotkb:ptc4(gene name)|psi-mi:ptc4(display_short)|uniprotkb:SPAC4A8.03c(orf name)	psi-mi:"MI:0096"(pull down)	Di et al. (2012)	doi:10.1038/emboj.2011.438|pubmed:22139357|imex:IM-17562|mint:MINT-8374053	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593905|mint:MINT-8374500|imex:IM-17562-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038783|refseq:NP_592843.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-168638|reactome:R-SPO-450341|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010515"(negative regulation of induction of conjugation with cellular fusion)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904789"(regulation of mitotic actomyosin contractile ring maintenance)|go:"GO:1990625"(negative regulation of cytoplasmic translational initiation in response to stress)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:0007231"(osmosensory signaling pathway)|ensemblfungi:SPAC24B11.06c(gene)|ensemblfungi:SPAC24B11.06c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|reactome:R-SPO-6798695|reactome:R-SPO-418592|reactome:R-SPO-432142|reactome:R-SPO-525793|reactome:R-SPO-198753|reactome:R-SPO-5668599|reactome:R-SPO-193648|reactome:R-SPO-2559580|reactome:R-SPO-2871796|reactome:R-SPO-450321|reactome:R-SPO-9007892|mint:MINT-8374512(identity)	interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|refseq:NP_593814.1|ensemblfungi:SPAC4A8.03c(gene)|ensemblfungi:SPAC4A8.03c.1(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0023052"(signaling)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0061191"(positive regulation of vacuole fusion, non-autophagic)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901098"(positive regulation of autophagosome maturation)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR036457|mint:MINT-8374502(identity)	-	-	comment:mint|function:Has a role in the regulation of vacuole fusion	figure legend:f4b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/10	2014/10/16	rogid:kBCikrs/6vxOvBRFqt4X4Up1IS8284812	rogid:Kyul2EchWERR1gJbaaz7tAHwKqc284812	intact-crc:0968F6073B81B3B0|rigid:0dDfSa6pNbWBM8T4v458ZUiPc+k	false	glutathione s tranferase tag:?-?(MINT-8374518)	binding-associated region:1-28(MINT-8374521)|mutation decreasing interaction:27-27(MINT-8374523)|tag:?-?(MINT-8374509)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q09892	uniprotkb:O14156	intact:EBI-3648525|ensemblfungi:"SPAC24B11.06c.1:pep"	intact:EBI-7593590|uniprotkb:Q9UR02|intact:MINT-4670968|ensemblfungi:"SPAC4A8.03c.1:pep"	psi-mi:hog1_schpo(display_long)|uniprotkb:sty1(gene name)|psi-mi:sty1(display_short)|uniprotkb:hog1(gene name synonym)|uniprotkb:phh1(gene name synonym)|uniprotkb:spc1(gene name synonym)|uniprotkb:MAP kinase spc1(gene name synonym)|uniprotkb:SPAC24B11.06c(orf name)	psi-mi:pp2c4_schpo(display_long)|uniprotkb:ptc4(gene name)|psi-mi:ptc4(display_short)|uniprotkb:SPAC4A8.03c(orf name)	psi-mi:"MI:0096"(pull down)	Di et al. (2012)	doi:10.1038/emboj.2011.438|pubmed:22139357|imex:IM-17562|mint:MINT-8374053	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593949|mint:MINT-8374526|imex:IM-17562-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038783|refseq:NP_592843.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-168638|reactome:R-SPO-450341|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010515"(negative regulation of induction of conjugation with cellular fusion)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904789"(regulation of mitotic actomyosin contractile ring maintenance)|go:"GO:1990625"(negative regulation of cytoplasmic translational initiation in response to stress)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:0007231"(osmosensory signaling pathway)|ensemblfungi:SPAC24B11.06c(gene)|ensemblfungi:SPAC24B11.06c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|reactome:R-SPO-6798695|reactome:R-SPO-418592|reactome:R-SPO-432142|reactome:R-SPO-525793|reactome:R-SPO-198753|reactome:R-SPO-5668599|reactome:R-SPO-193648|reactome:R-SPO-2559580|reactome:R-SPO-2871796|reactome:R-SPO-450321|reactome:R-SPO-9007892|mint:MINT-8374536(identity)	interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|refseq:NP_593814.1|ensemblfungi:SPAC4A8.03c(gene)|ensemblfungi:SPAC4A8.03c.1(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0023052"(signaling)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0061191"(positive regulation of vacuole fusion, non-autophagic)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901098"(positive regulation of autophagosome maturation)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR036457|mint:MINT-8374528(identity)	-	-	comment:mint|function:Has a role in the regulation of vacuole fusion	figure legend:f4b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/10	2014/10/16	rogid:kBCikrs/6vxOvBRFqt4X4Up1IS8284812	rogid:Kyul2EchWERR1gJbaaz7tAHwKqc284812	intact-crc:65B75621082A3BEF|rigid:0dDfSa6pNbWBM8T4v458ZUiPc+k	false	glutathione s tranferase tag:?-?(MINT-8374537)	mutation decreasing interaction:27-27(MINT-8374529)|mutation decreasing interaction:10-10(MINT-8374545)|binding-associated region:1-28(MINT-8374531)|mutation decreasing interaction:8-8(MINT-8374542)|tag:?-?(MINT-8374533)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)