#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P10275	uniprotkb:P00925	intact:EBI-608057|ensembl:ENSP00000363822|ensembl:ENSP00000484033|uniprotkb:A2RUN2|uniprotkb:B1AKD7|uniprotkb:Q9UD95|intact:EBI-11476138|uniprotkb:A0A0B4J1T2|uniprotkb:C0JKD3|uniprotkb:C0JKD4|uniprotkb:E7EVX6	intact:EBI-6475|uniprotkb:D3DLC2|uniprotkb:P99013|ensemblfungi:YHR174W	psi-mi:andr_human(display_long)|uniprotkb:Dihydrotestosterone receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 4(gene name synonym)|uniprotkb:AR(gene name)|psi-mi:AR(display_short)|uniprotkb:DHTR(gene name synonym)|uniprotkb:NR3C4(gene name synonym)	psi-mi:eno2_yeast(display_long)|uniprotkb:YHR174W(locus name)|uniprotkb:ENO2(gene name)|psi-mi:ENO2(display_short)|uniprotkb:ENOB(gene name synonym)|uniprotkb:2-phosphoglycerate dehydratase 2(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase 2(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Austin et al. (2012)	pubmed:22116683|imex:IM-16617	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327763|imex:IM-16617-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169083(gene)|ensembl:ENST00000374690(transcript)|ensembl:ENST00000612452(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005497"(androgen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045720"(negative regulation of integrin biosynthetic process)|go:"GO:0045726"(positive regulation of integrin biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0048645"(animal organ formation)|go:"GO:0048808"(male genitalia morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0060520"(activation of prostate induction by androgen receptor signaling pathway)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070974"(POU domain binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001103(Androgen receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10275|rcsb pdb:1E3G|rcsb pdb:1GS4|rcsb pdb:1T5Z|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1XJ7|rcsb pdb:1XOW|rcsb pdb:1XQ3|rcsb pdb:1Z95|rcsb pdb:2AM9|rcsb pdb:2AMA|rcsb pdb:2AMB|rcsb pdb:2AO6|rcsb pdb:2AX6|rcsb pdb:2AX7|rcsb pdb:2AX8|rcsb pdb:2AX9|rcsb pdb:2AXA|rcsb pdb:2HVC|rcsb pdb:2OZ7|rcsb pdb:2PIO|rcsb pdb:2PIP|rcsb pdb:2PIQ|rcsb pdb:2PIR|rcsb pdb:2PIT|rcsb pdb:2PIU|rcsb pdb:2PIV|rcsb pdb:2PIW|rcsb pdb:2PIX|rcsb pdb:2PKL|rcsb pdb:2PNU|rcsb pdb:2Q7I|rcsb pdb:2Q7J|rcsb pdb:2Q7K|rcsb pdb:2Q7L|rcsb pdb:2YHD|rcsb pdb:2YLO|rcsb pdb:2YLP|rcsb pdb:2YLQ|rcsb pdb:2Z4J|rcsb pdb:3B5R|rcsb pdb:3B65|rcsb pdb:3B66|rcsb pdb:3B67|rcsb pdb:3B68|rcsb pdb:3BTR|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:3RLJ|rcsb pdb:3RLL|rcsb pdb:3V49|rcsb pdb:3V4A|rcsb pdb:3ZQT|rcsb pdb:4HLW|rcsb pdb:4K7A|rcsb pdb:4OEA|rcsb pdb:4OED|rcsb pdb:4OEY|rcsb pdb:4OEZ|rcsb pdb:4OFR|rcsb pdb:4OFU|rcsb pdb:4OGH|rcsb pdb:4OH5|rcsb pdb:4OH6|rcsb pdb:4OHA|rcsb pdb:4OIL|rcsb pdb:4OIU|rcsb pdb:4OJ9|rcsb pdb:4OJB|rcsb pdb:4OK1|rcsb pdb:4OKB|rcsb pdb:4OKT|rcsb pdb:4OKW|rcsb pdb:4OKX|rcsb pdb:4OLM|rcsb pdb:4QL8|rcsb pdb:5CJ6|rcsb pdb:5JJM|rcsb pdb:5T8E|rcsb pdb:5T8J|rcsb pdb:5V8Q|rcsb pdb:5VO4|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-8940973|refseq:NP_000035.2|ensembl:ENSP00000363822|ensembl:ENST00000504326|ensembl:ENSP00000421155|ensembl:ENSP00000484033|refseq:NP_001011645.1|refseq:NP_001334990.1|refseq:NP_001334992.1|refseq:NP_001334993.1|dip:DIP-125N	refseq:NP_012044.1|sgd:S000001217|mint:P00925|dip:DIP-4777N|ensemblfungi:YHR174W(gene)|ensemblfungi:YHR174W_mRNA(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:1904408"(melatonin binding)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|reactome:R-SCE-70171|reactome:R-SCE-70263	psi-mi:"MI:0469"(intact)	-	crc64:04599565F58A7643	figure legend:Fig 3, Supplementary Table 1.|comment:"The Hsp90 chaperonin (Hsp82)  was associated with the rAR in both the unliganded (light) and liganded (heavy) receptor state (Fig. 3B). Separately, Hsp70 chaperonin proteins (SSA1, SSA2, SSA4) are associated with rAR primarily in the unliganded receptor state."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/01/20	2016/03/30	rogid:fsxn0EE6wCkb0Y9BsdUtB+FmHAg9606	rogid:ipDLF3SxQBFjehTEVHFml/A79xk559292	intact-crc:0B74C5AB264DCF6D|rigid:emg+CftuSAFsPSJOE4ocRKqjcvs	false	tandem tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P10275	uniprotkb:P60010	intact:EBI-608057|ensembl:ENSP00000363822|ensembl:ENSP00000484033|uniprotkb:A2RUN2|uniprotkb:B1AKD7|uniprotkb:Q9UD95|intact:EBI-11476138|uniprotkb:A0A0B4J1T2|uniprotkb:C0JKD3|uniprotkb:C0JKD4|uniprotkb:E7EVX6	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	psi-mi:andr_human(display_long)|uniprotkb:Dihydrotestosterone receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 4(gene name synonym)|uniprotkb:AR(gene name)|psi-mi:AR(display_short)|uniprotkb:DHTR(gene name synonym)|uniprotkb:NR3C4(gene name synonym)	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:"MI:0030"(cross-linking study)	Austin et al. (2012)	pubmed:22116683|imex:IM-16617	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327763|imex:IM-16617-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169083(gene)|ensembl:ENST00000374690(transcript)|ensembl:ENST00000612452(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005497"(androgen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045720"(negative regulation of integrin biosynthetic process)|go:"GO:0045726"(positive regulation of integrin biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0048645"(animal organ formation)|go:"GO:0048808"(male genitalia morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0060520"(activation of prostate induction by androgen receptor signaling pathway)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070974"(POU domain binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001103(Androgen receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10275|rcsb pdb:1E3G|rcsb pdb:1GS4|rcsb pdb:1T5Z|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1XJ7|rcsb pdb:1XOW|rcsb pdb:1XQ3|rcsb pdb:1Z95|rcsb pdb:2AM9|rcsb pdb:2AMA|rcsb pdb:2AMB|rcsb pdb:2AO6|rcsb pdb:2AX6|rcsb pdb:2AX7|rcsb pdb:2AX8|rcsb pdb:2AX9|rcsb pdb:2AXA|rcsb pdb:2HVC|rcsb pdb:2OZ7|rcsb pdb:2PIO|rcsb pdb:2PIP|rcsb pdb:2PIQ|rcsb pdb:2PIR|rcsb pdb:2PIT|rcsb pdb:2PIU|rcsb pdb:2PIV|rcsb pdb:2PIW|rcsb pdb:2PIX|rcsb pdb:2PKL|rcsb pdb:2PNU|rcsb pdb:2Q7I|rcsb pdb:2Q7J|rcsb pdb:2Q7K|rcsb pdb:2Q7L|rcsb pdb:2YHD|rcsb pdb:2YLO|rcsb pdb:2YLP|rcsb pdb:2YLQ|rcsb pdb:2Z4J|rcsb pdb:3B5R|rcsb pdb:3B65|rcsb pdb:3B66|rcsb pdb:3B67|rcsb pdb:3B68|rcsb pdb:3BTR|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:3RLJ|rcsb pdb:3RLL|rcsb pdb:3V49|rcsb pdb:3V4A|rcsb pdb:3ZQT|rcsb pdb:4HLW|rcsb pdb:4K7A|rcsb pdb:4OEA|rcsb pdb:4OED|rcsb pdb:4OEY|rcsb pdb:4OEZ|rcsb pdb:4OFR|rcsb pdb:4OFU|rcsb pdb:4OGH|rcsb pdb:4OH5|rcsb pdb:4OH6|rcsb pdb:4OHA|rcsb pdb:4OIL|rcsb pdb:4OIU|rcsb pdb:4OJ9|rcsb pdb:4OJB|rcsb pdb:4OK1|rcsb pdb:4OKB|rcsb pdb:4OKT|rcsb pdb:4OKW|rcsb pdb:4OKX|rcsb pdb:4OLM|rcsb pdb:4QL8|rcsb pdb:5CJ6|rcsb pdb:5JJM|rcsb pdb:5T8E|rcsb pdb:5T8J|rcsb pdb:5V8Q|rcsb pdb:5VO4|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-8940973|refseq:NP_000035.2|ensembl:ENSP00000363822|ensembl:ENST00000504326|ensembl:ENSP00000421155|ensembl:ENSP00000484033|refseq:NP_001011645.1|refseq:NP_001334990.1|refseq:NP_001334992.1|refseq:NP_001334993.1|dip:DIP-125N	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026	psi-mi:"MI:0469"(intact)	-	crc64:87AC19B0B0BC9E71	figure legend:Fig 3, Supplementary Table 1.|comment:"The Hsp90 chaperonin (Hsp82)  was associated with the rAR in both the unliganded (light) and liganded (heavy) receptor state (Fig. 3B). Separately, Hsp70 chaperonin proteins (SSA1, SSA2, SSA4) are associated with rAR primarily in the unliganded receptor state."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/01/20	2016/03/30	rogid:fsxn0EE6wCkb0Y9BsdUtB+FmHAg9606	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	intact-crc:0B74C5AB264DCF6D|rigid:emg+CftuSAFsPSJOE4ocRKqjcvs	false	tandem tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P10275	uniprotkb:P15108	intact:EBI-608057|ensembl:ENSP00000363822|ensembl:ENSP00000484033|uniprotkb:A2RUN2|uniprotkb:B1AKD7|uniprotkb:Q9UD95|intact:EBI-11476138|uniprotkb:A0A0B4J1T2|uniprotkb:C0JKD3|uniprotkb:C0JKD4|uniprotkb:E7EVX6	intact:EBI-8666|ensemblfungi:YMR186W|uniprotkb:D6W010	psi-mi:andr_human(display_long)|uniprotkb:Dihydrotestosterone receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 4(gene name synonym)|uniprotkb:AR(gene name)|psi-mi:AR(display_short)|uniprotkb:DHTR(gene name synonym)|uniprotkb:NR3C4(gene name synonym)	psi-mi:hsc82_yeast(display_long)|uniprotkb:HSC82(gene name)|psi-mi:HSC82(display_short)|uniprotkb:YMR186W(locus name)|uniprotkb:YM8010.16(orf name)|uniprotkb:Heat shock protein Hsp90 constitutive isoform(gene name synonym)|uniprotkb:82 kDa heat shock cognate protein(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Austin et al. (2012)	pubmed:22116683|imex:IM-16617	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327763|imex:IM-16617-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169083(gene)|ensembl:ENST00000374690(transcript)|ensembl:ENST00000612452(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005497"(androgen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045720"(negative regulation of integrin biosynthetic process)|go:"GO:0045726"(positive regulation of integrin biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0048645"(animal organ formation)|go:"GO:0048808"(male genitalia morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0060520"(activation of prostate induction by androgen receptor signaling pathway)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070974"(POU domain binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001103(Androgen receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10275|rcsb pdb:1E3G|rcsb pdb:1GS4|rcsb pdb:1T5Z|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1XJ7|rcsb pdb:1XOW|rcsb pdb:1XQ3|rcsb pdb:1Z95|rcsb pdb:2AM9|rcsb pdb:2AMA|rcsb pdb:2AMB|rcsb pdb:2AO6|rcsb pdb:2AX6|rcsb pdb:2AX7|rcsb pdb:2AX8|rcsb pdb:2AX9|rcsb pdb:2AXA|rcsb pdb:2HVC|rcsb pdb:2OZ7|rcsb pdb:2PIO|rcsb pdb:2PIP|rcsb pdb:2PIQ|rcsb pdb:2PIR|rcsb pdb:2PIT|rcsb pdb:2PIU|rcsb pdb:2PIV|rcsb pdb:2PIW|rcsb pdb:2PIX|rcsb pdb:2PKL|rcsb pdb:2PNU|rcsb pdb:2Q7I|rcsb pdb:2Q7J|rcsb pdb:2Q7K|rcsb pdb:2Q7L|rcsb pdb:2YHD|rcsb pdb:2YLO|rcsb pdb:2YLP|rcsb pdb:2YLQ|rcsb pdb:2Z4J|rcsb pdb:3B5R|rcsb pdb:3B65|rcsb pdb:3B66|rcsb pdb:3B67|rcsb pdb:3B68|rcsb pdb:3BTR|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:3RLJ|rcsb pdb:3RLL|rcsb pdb:3V49|rcsb pdb:3V4A|rcsb pdb:3ZQT|rcsb pdb:4HLW|rcsb pdb:4K7A|rcsb pdb:4OEA|rcsb pdb:4OED|rcsb pdb:4OEY|rcsb pdb:4OEZ|rcsb pdb:4OFR|rcsb pdb:4OFU|rcsb pdb:4OGH|rcsb pdb:4OH5|rcsb pdb:4OH6|rcsb pdb:4OHA|rcsb pdb:4OIL|rcsb pdb:4OIU|rcsb pdb:4OJ9|rcsb pdb:4OJB|rcsb pdb:4OK1|rcsb pdb:4OKB|rcsb pdb:4OKT|rcsb pdb:4OKW|rcsb pdb:4OKX|rcsb pdb:4OLM|rcsb pdb:4QL8|rcsb pdb:5CJ6|rcsb pdb:5JJM|rcsb pdb:5T8E|rcsb pdb:5T8J|rcsb pdb:5V8Q|rcsb pdb:5VO4|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-8940973|refseq:NP_000035.2|ensembl:ENSP00000363822|ensembl:ENST00000504326|ensembl:ENSP00000421155|ensembl:ENSP00000484033|refseq:NP_001011645.1|refseq:NP_001334990.1|refseq:NP_001334992.1|refseq:NP_001334993.1|dip:DIP-125N	interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:6XLB|rcsb pdb:6XLC|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|ensemblfungi:YMR186W(gene)|ensemblfungi:YMR186W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:6XLG|rcsb pdb:6XLH|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-9009391|refseq:NP_013911.1|sgd:S000004798|mint:P15108|dip:DIP-1524N	psi-mi:"MI:0469"(intact)	-	crc64:DBD41524091B1F9B	figure legend:Fig 3, Supplementary Table 1.|comment:"The Hsp90 chaperonin (Hsp82)  was associated with the rAR in both the unliganded (light) and liganded (heavy) receptor state (Fig. 3B). Separately, Hsp70 chaperonin proteins (SSA1, SSA2, SSA4) are associated with rAR primarily in the unliganded receptor state."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/01/20	2016/03/30	rogid:fsxn0EE6wCkb0Y9BsdUtB+FmHAg9606	rogid:A0Na3L9N4cl7acd9lSGiwKAYK1o559292	intact-crc:0B74C5AB264DCF6D|rigid:emg+CftuSAFsPSJOE4ocRKqjcvs	false	tandem tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P10275	uniprotkb:P10592	intact:EBI-608057|ensembl:ENSP00000363822|ensembl:ENSP00000484033|uniprotkb:A2RUN2|uniprotkb:B1AKD7|uniprotkb:Q9UD95|intact:EBI-11476138|uniprotkb:A0A0B4J1T2|uniprotkb:C0JKD3|uniprotkb:C0JKD4|uniprotkb:E7EVX6	intact:EBI-8603|uniprotkb:D6VXY0|ensemblfungi:YLL024C	psi-mi:andr_human(display_long)|uniprotkb:Dihydrotestosterone receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 4(gene name synonym)|uniprotkb:AR(gene name)|psi-mi:AR(display_short)|uniprotkb:DHTR(gene name synonym)|uniprotkb:NR3C4(gene name synonym)	psi-mi:hsp72_yeast(display_long)|uniprotkb:L0931(orf name)|uniprotkb:YLL024C(locus name)|uniprotkb:SSA2(gene name)|psi-mi:SSA2(display_short)	psi-mi:"MI:0030"(cross-linking study)	Austin et al. (2012)	pubmed:22116683|imex:IM-16617	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327763|imex:IM-16617-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169083(gene)|ensembl:ENST00000374690(transcript)|ensembl:ENST00000612452(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005497"(androgen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045720"(negative regulation of integrin biosynthetic process)|go:"GO:0045726"(positive regulation of integrin biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0048645"(animal organ formation)|go:"GO:0048808"(male genitalia morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0060520"(activation of prostate induction by androgen receptor signaling pathway)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070974"(POU domain binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001103(Androgen receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10275|rcsb pdb:1E3G|rcsb pdb:1GS4|rcsb pdb:1T5Z|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1XJ7|rcsb pdb:1XOW|rcsb pdb:1XQ3|rcsb pdb:1Z95|rcsb pdb:2AM9|rcsb pdb:2AMA|rcsb pdb:2AMB|rcsb pdb:2AO6|rcsb pdb:2AX6|rcsb pdb:2AX7|rcsb pdb:2AX8|rcsb pdb:2AX9|rcsb pdb:2AXA|rcsb pdb:2HVC|rcsb pdb:2OZ7|rcsb pdb:2PIO|rcsb pdb:2PIP|rcsb pdb:2PIQ|rcsb pdb:2PIR|rcsb pdb:2PIT|rcsb pdb:2PIU|rcsb pdb:2PIV|rcsb pdb:2PIW|rcsb pdb:2PIX|rcsb pdb:2PKL|rcsb pdb:2PNU|rcsb pdb:2Q7I|rcsb pdb:2Q7J|rcsb pdb:2Q7K|rcsb pdb:2Q7L|rcsb pdb:2YHD|rcsb pdb:2YLO|rcsb pdb:2YLP|rcsb pdb:2YLQ|rcsb pdb:2Z4J|rcsb pdb:3B5R|rcsb pdb:3B65|rcsb pdb:3B66|rcsb pdb:3B67|rcsb pdb:3B68|rcsb pdb:3BTR|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:3RLJ|rcsb pdb:3RLL|rcsb pdb:3V49|rcsb pdb:3V4A|rcsb pdb:3ZQT|rcsb pdb:4HLW|rcsb pdb:4K7A|rcsb pdb:4OEA|rcsb pdb:4OED|rcsb pdb:4OEY|rcsb pdb:4OEZ|rcsb pdb:4OFR|rcsb pdb:4OFU|rcsb pdb:4OGH|rcsb pdb:4OH5|rcsb pdb:4OH6|rcsb pdb:4OHA|rcsb pdb:4OIL|rcsb pdb:4OIU|rcsb pdb:4OJ9|rcsb pdb:4OJB|rcsb pdb:4OK1|rcsb pdb:4OKB|rcsb pdb:4OKT|rcsb pdb:4OKW|rcsb pdb:4OKX|rcsb pdb:4OLM|rcsb pdb:4QL8|rcsb pdb:5CJ6|rcsb pdb:5JJM|rcsb pdb:5T8E|rcsb pdb:5T8J|rcsb pdb:5V8Q|rcsb pdb:5VO4|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-8940973|refseq:NP_000035.2|ensembl:ENSP00000363822|ensembl:ENST00000504326|ensembl:ENSP00000421155|ensembl:ENSP00000484033|refseq:NP_001011645.1|refseq:NP_001334990.1|refseq:NP_001334992.1|refseq:NP_001334993.1|dip:DIP-125N	refseq:NP_013076.1|sgd:S000003947|mint:P10592|dip:DIP-2265N|ensemblfungi:YLL024C(gene)|ensemblfungi:YLL024C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0042026"(protein refolding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|reactome:R-SCE-3371497|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|reactome:R-SCE-8876725	psi-mi:"MI:0469"(intact)	-	crc64:129049E21C9DD1F3	figure legend:Fig 3, Supplementary Table 1.|comment:"The Hsp90 chaperonin (Hsp82)  was associated with the rAR in both the unliganded (light) and liganded (heavy) receptor state (Fig. 3B). Separately, Hsp70 chaperonin proteins (SSA1, SSA2, SSA4) are associated with rAR primarily in the unliganded receptor state."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/01/20	2016/03/30	rogid:fsxn0EE6wCkb0Y9BsdUtB+FmHAg9606	rogid:FakCbxCBdOtSSqw2C4u76D3opS0559292	intact-crc:0B74C5AB264DCF6D|rigid:emg+CftuSAFsPSJOE4ocRKqjcvs	false	tandem tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P10275	uniprotkb:P00359	intact:EBI-608057|ensembl:ENSP00000363822|ensembl:ENSP00000484033|uniprotkb:A2RUN2|uniprotkb:B1AKD7|uniprotkb:Q9UD95|intact:EBI-11476138|uniprotkb:A0A0B4J1T2|uniprotkb:C0JKD3|uniprotkb:C0JKD4|uniprotkb:E7EVX6	intact:EBI-7218|uniprotkb:Q6Q5P9|uniprotkb:D6VUX4|ensemblfungi:YGR192C	psi-mi:andr_human(display_long)|uniprotkb:Dihydrotestosterone receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 4(gene name synonym)|uniprotkb:AR(gene name)|psi-mi:AR(display_short)|uniprotkb:DHTR(gene name synonym)|uniprotkb:NR3C4(gene name synonym)	psi-mi:g3p3_yeast(display_long)|uniprotkb:TDH3(gene name)|psi-mi:TDH3(display_short)|uniprotkb:GPD3(gene name synonym)|uniprotkb:YGR192C(locus name)|uniprotkb:G7576(orf name)	psi-mi:"MI:0030"(cross-linking study)	Austin et al. (2012)	pubmed:22116683|imex:IM-16617	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327763|imex:IM-16617-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169083(gene)|ensembl:ENST00000374690(transcript)|ensembl:ENST00000612452(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005497"(androgen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045720"(negative regulation of integrin biosynthetic process)|go:"GO:0045726"(positive regulation of integrin biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0048645"(animal organ formation)|go:"GO:0048808"(male genitalia morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0060520"(activation of prostate induction by androgen receptor signaling pathway)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070974"(POU domain binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001103(Androgen receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10275|rcsb pdb:1E3G|rcsb pdb:1GS4|rcsb pdb:1T5Z|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1XJ7|rcsb pdb:1XOW|rcsb pdb:1XQ3|rcsb pdb:1Z95|rcsb pdb:2AM9|rcsb pdb:2AMA|rcsb pdb:2AMB|rcsb pdb:2AO6|rcsb pdb:2AX6|rcsb pdb:2AX7|rcsb pdb:2AX8|rcsb pdb:2AX9|rcsb pdb:2AXA|rcsb pdb:2HVC|rcsb pdb:2OZ7|rcsb pdb:2PIO|rcsb pdb:2PIP|rcsb pdb:2PIQ|rcsb pdb:2PIR|rcsb pdb:2PIT|rcsb pdb:2PIU|rcsb pdb:2PIV|rcsb pdb:2PIW|rcsb pdb:2PIX|rcsb pdb:2PKL|rcsb pdb:2PNU|rcsb pdb:2Q7I|rcsb pdb:2Q7J|rcsb pdb:2Q7K|rcsb pdb:2Q7L|rcsb pdb:2YHD|rcsb pdb:2YLO|rcsb pdb:2YLP|rcsb pdb:2YLQ|rcsb pdb:2Z4J|rcsb pdb:3B5R|rcsb pdb:3B65|rcsb pdb:3B66|rcsb pdb:3B67|rcsb pdb:3B68|rcsb pdb:3BTR|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:3RLJ|rcsb pdb:3RLL|rcsb pdb:3V49|rcsb pdb:3V4A|rcsb pdb:3ZQT|rcsb pdb:4HLW|rcsb pdb:4K7A|rcsb pdb:4OEA|rcsb pdb:4OED|rcsb pdb:4OEY|rcsb pdb:4OEZ|rcsb pdb:4OFR|rcsb pdb:4OFU|rcsb pdb:4OGH|rcsb pdb:4OH5|rcsb pdb:4OH6|rcsb pdb:4OHA|rcsb pdb:4OIL|rcsb pdb:4OIU|rcsb pdb:4OJ9|rcsb pdb:4OJB|rcsb pdb:4OK1|rcsb pdb:4OKB|rcsb pdb:4OKT|rcsb pdb:4OKW|rcsb pdb:4OKX|rcsb pdb:4OLM|rcsb pdb:4QL8|rcsb pdb:5CJ6|rcsb pdb:5JJM|rcsb pdb:5T8E|rcsb pdb:5T8J|rcsb pdb:5V8Q|rcsb pdb:5VO4|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-8940973|refseq:NP_000035.2|ensembl:ENSP00000363822|ensembl:ENST00000504326|ensembl:ENSP00000421155|ensembl:ENSP00000484033|refseq:NP_001011645.1|refseq:NP_001334990.1|refseq:NP_001334992.1|refseq:NP_001334993.1|dip:DIP-125N	sgd:S000003424|refseq:NP_011708.3|mint:P00359|dip:DIP-4309N|ensemblfungi:YGR192C(gene)|ensemblfungi:YGR192C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0015886"(heme transport)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904408"(melatonin binding)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|rcsb pdb:3PYM|rcsb pdb:4IQ8|reactome:R-SCE-70171|reactome:R-SCE-70263	psi-mi:"MI:0469"(intact)	-	crc64:6CFFFEE7061BC36F	figure legend:Fig 3, Supplementary Table 1.|comment:"The Hsp90 chaperonin (Hsp82)  was associated with the rAR in both the unliganded (light) and liganded (heavy) receptor state (Fig. 3B). Separately, Hsp70 chaperonin proteins (SSA1, SSA2, SSA4) are associated with rAR primarily in the unliganded receptor state."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/01/20	2016/03/30	rogid:fsxn0EE6wCkb0Y9BsdUtB+FmHAg9606	rogid:SCaeBRAWlROkzprJe0JgOB3lNZ0559292	intact-crc:0B74C5AB264DCF6D|rigid:emg+CftuSAFsPSJOE4ocRKqjcvs	false	tandem tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P10275	uniprotkb:P10591	intact:EBI-608057|ensembl:ENSP00000363822|ensembl:ENSP00000484033|uniprotkb:A2RUN2|uniprotkb:B1AKD7|uniprotkb:Q9UD95|intact:EBI-11476138|uniprotkb:A0A0B4J1T2|uniprotkb:C0JKD3|uniprotkb:C0JKD4|uniprotkb:E7EVX6	intact:EBI-8591|uniprotkb:D6VPL2|ensemblfungi:YAL005C	psi-mi:andr_human(display_long)|uniprotkb:Dihydrotestosterone receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 4(gene name synonym)|uniprotkb:AR(gene name)|psi-mi:AR(display_short)|uniprotkb:DHTR(gene name synonym)|uniprotkb:NR3C4(gene name synonym)	psi-mi:hsp71_yeast(display_long)|uniprotkb:YAL005C(locus name)|uniprotkb:SSA1(gene name)|psi-mi:SSA1(display_short)|uniprotkb:Heat shock protein YG100(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Austin et al. (2012)	pubmed:22116683|imex:IM-16617	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327763|imex:IM-16617-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169083(gene)|ensembl:ENST00000374690(transcript)|ensembl:ENST00000612452(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005497"(androgen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045720"(negative regulation of integrin biosynthetic process)|go:"GO:0045726"(positive regulation of integrin biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0048645"(animal organ formation)|go:"GO:0048808"(male genitalia morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0060520"(activation of prostate induction by androgen receptor signaling pathway)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070974"(POU domain binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001103(Androgen receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10275|rcsb pdb:1E3G|rcsb pdb:1GS4|rcsb pdb:1T5Z|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1XJ7|rcsb pdb:1XOW|rcsb pdb:1XQ3|rcsb pdb:1Z95|rcsb pdb:2AM9|rcsb pdb:2AMA|rcsb pdb:2AMB|rcsb pdb:2AO6|rcsb pdb:2AX6|rcsb pdb:2AX7|rcsb pdb:2AX8|rcsb pdb:2AX9|rcsb pdb:2AXA|rcsb pdb:2HVC|rcsb pdb:2OZ7|rcsb pdb:2PIO|rcsb pdb:2PIP|rcsb pdb:2PIQ|rcsb pdb:2PIR|rcsb pdb:2PIT|rcsb pdb:2PIU|rcsb pdb:2PIV|rcsb pdb:2PIW|rcsb pdb:2PIX|rcsb pdb:2PKL|rcsb pdb:2PNU|rcsb pdb:2Q7I|rcsb pdb:2Q7J|rcsb pdb:2Q7K|rcsb pdb:2Q7L|rcsb pdb:2YHD|rcsb pdb:2YLO|rcsb pdb:2YLP|rcsb pdb:2YLQ|rcsb pdb:2Z4J|rcsb pdb:3B5R|rcsb pdb:3B65|rcsb pdb:3B66|rcsb pdb:3B67|rcsb pdb:3B68|rcsb pdb:3BTR|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:3RLJ|rcsb pdb:3RLL|rcsb pdb:3V49|rcsb pdb:3V4A|rcsb pdb:3ZQT|rcsb pdb:4HLW|rcsb pdb:4K7A|rcsb pdb:4OEA|rcsb pdb:4OED|rcsb pdb:4OEY|rcsb pdb:4OEZ|rcsb pdb:4OFR|rcsb pdb:4OFU|rcsb pdb:4OGH|rcsb pdb:4OH5|rcsb pdb:4OH6|rcsb pdb:4OHA|rcsb pdb:4OIL|rcsb pdb:4OIU|rcsb pdb:4OJ9|rcsb pdb:4OJB|rcsb pdb:4OK1|rcsb pdb:4OKB|rcsb pdb:4OKT|rcsb pdb:4OKW|rcsb pdb:4OKX|rcsb pdb:4OLM|rcsb pdb:4QL8|rcsb pdb:5CJ6|rcsb pdb:5JJM|rcsb pdb:5T8E|rcsb pdb:5T8J|rcsb pdb:5V8Q|rcsb pdb:5VO4|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-8940973|refseq:NP_000035.2|ensembl:ENSP00000363822|ensembl:ENST00000504326|ensembl:ENSP00000421155|ensembl:ENSP00000484033|refseq:NP_001011645.1|refseq:NP_001334990.1|refseq:NP_001334992.1|refseq:NP_001334993.1|dip:DIP-125N	refseq:NP_009396.2|sgd:S000000004|mint:P10591|dip:DIP-2253N|ensemblfungi:YAL005C(gene)|ensemblfungi:YAL005C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0042026"(protein refolding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:3LCA|rcsb pdb:5LYN|rcsb pdb:5Z8I|rcsb pdb:5Z8Q	psi-mi:"MI:0469"(intact)	-	crc64:249D8A3BC42527CA	figure legend:Fig 3, Supplementary Table 1.|comment:"The Hsp90 chaperonin (Hsp82)  was associated with the rAR in both the unliganded (light) and liganded (heavy) receptor state (Fig. 3B). Separately, Hsp70 chaperonin proteins (SSA1, SSA2, SSA4) are associated with rAR primarily in the unliganded receptor state."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/01/20	2016/03/30	rogid:fsxn0EE6wCkb0Y9BsdUtB+FmHAg9606	rogid:3GvAKzWWSou3MW9HqZVxC+Wkkqk559292	intact-crc:0B74C5AB264DCF6D|rigid:emg+CftuSAFsPSJOE4ocRKqjcvs	false	tandem tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P10275	uniprotkb:P02994	intact:EBI-608057|ensembl:ENSP00000363822|ensembl:ENSP00000484033|uniprotkb:A2RUN2|uniprotkb:B1AKD7|uniprotkb:Q9UD95|intact:EBI-11476138|uniprotkb:A0A0B4J1T2|uniprotkb:C0JKD3|uniprotkb:C0JKD4|uniprotkb:E7EVX6	intact:EBI-6314|uniprotkb:Q7Z7U8|uniprotkb:Q7Z8Q8|uniprotkb:Q7Z8Q9|uniprotkb:D6VQB6|ensemblfungi:YBR118W|ensemblfungi:YPR080W	psi-mi:andr_human(display_long)|uniprotkb:Dihydrotestosterone receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 4(gene name synonym)|uniprotkb:AR(gene name)|psi-mi:AR(display_short)|uniprotkb:DHTR(gene name synonym)|uniprotkb:NR3C4(gene name synonym)	psi-mi:ef1a_yeast(display_long)|uniprotkb:TEF1(gene name)|psi-mi:TEF1(display_short)|uniprotkb:YPR080W(locus name)|uniprotkb:P9513.7(orf name)|uniprotkb:TEF2(gene name)|psi-mi:TEF2(display_short)|uniprotkb:YBR118W(locus name)|uniprotkb:YBR0913(orf name)|uniprotkb:Translation elongation factor 1A(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1A(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Austin et al. (2012)	pubmed:22116683|imex:IM-16617	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327763|imex:IM-16617-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169083(gene)|ensembl:ENST00000374690(transcript)|ensembl:ENST00000612452(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005497"(androgen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045720"(negative regulation of integrin biosynthetic process)|go:"GO:0045726"(positive regulation of integrin biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0048645"(animal organ formation)|go:"GO:0048808"(male genitalia morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0060520"(activation of prostate induction by androgen receptor signaling pathway)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070974"(POU domain binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001103(Androgen receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10275|rcsb pdb:1E3G|rcsb pdb:1GS4|rcsb pdb:1T5Z|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1XJ7|rcsb pdb:1XOW|rcsb pdb:1XQ3|rcsb pdb:1Z95|rcsb pdb:2AM9|rcsb pdb:2AMA|rcsb pdb:2AMB|rcsb pdb:2AO6|rcsb pdb:2AX6|rcsb pdb:2AX7|rcsb pdb:2AX8|rcsb pdb:2AX9|rcsb pdb:2AXA|rcsb pdb:2HVC|rcsb pdb:2OZ7|rcsb pdb:2PIO|rcsb pdb:2PIP|rcsb pdb:2PIQ|rcsb pdb:2PIR|rcsb pdb:2PIT|rcsb pdb:2PIU|rcsb pdb:2PIV|rcsb pdb:2PIW|rcsb pdb:2PIX|rcsb pdb:2PKL|rcsb pdb:2PNU|rcsb pdb:2Q7I|rcsb pdb:2Q7J|rcsb pdb:2Q7K|rcsb pdb:2Q7L|rcsb pdb:2YHD|rcsb pdb:2YLO|rcsb pdb:2YLP|rcsb pdb:2YLQ|rcsb pdb:2Z4J|rcsb pdb:3B5R|rcsb pdb:3B65|rcsb pdb:3B66|rcsb pdb:3B67|rcsb pdb:3B68|rcsb pdb:3BTR|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:3RLJ|rcsb pdb:3RLL|rcsb pdb:3V49|rcsb pdb:3V4A|rcsb pdb:3ZQT|rcsb pdb:4HLW|rcsb pdb:4K7A|rcsb pdb:4OEA|rcsb pdb:4OED|rcsb pdb:4OEY|rcsb pdb:4OEZ|rcsb pdb:4OFR|rcsb pdb:4OFU|rcsb pdb:4OGH|rcsb pdb:4OH5|rcsb pdb:4OH6|rcsb pdb:4OHA|rcsb pdb:4OIL|rcsb pdb:4OIU|rcsb pdb:4OJ9|rcsb pdb:4OJB|rcsb pdb:4OK1|rcsb pdb:4OKB|rcsb pdb:4OKT|rcsb pdb:4OKW|rcsb pdb:4OKX|rcsb pdb:4OLM|rcsb pdb:4QL8|rcsb pdb:5CJ6|rcsb pdb:5JJM|rcsb pdb:5T8E|rcsb pdb:5T8J|rcsb pdb:5V8Q|rcsb pdb:5VO4|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-8940973|refseq:NP_000035.2|ensembl:ENSP00000363822|ensembl:ENST00000504326|ensembl:ENSP00000421155|ensembl:ENSP00000484033|refseq:NP_001011645.1|refseq:NP_001334990.1|refseq:NP_001334992.1|refseq:NP_001334993.1|dip:DIP-125N	refseq:NP_009676.1|refseq:NP_015405.1|sgd:S000006284|sgd:S000000322|mint:P02994|dip:DIP-2250N|ensemblfungi:YBR118W(gene)|ensemblfungi:YBR118W_mRNA(transcript)|ensemblfungi:YPR080W(gene)|ensemblfungi:YPR080W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043022"(ribosome binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:1904408"(melatonin binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|rcsb pdb:1F60|rcsb pdb:1G7C|rcsb pdb:1IJE|rcsb pdb:1IJF|rcsb pdb:2B7B|rcsb pdb:2B7C|rcsb pdb:5O8W|reactome:R-SCE-156842|reactome:R-SCE-3371511|reactome:R-SCE-6798695|reactome:R-SCE-8876725	psi-mi:"MI:0469"(intact)	-	crc64:411C66D830716576	figure legend:Fig 3, Supplementary Table 1.|comment:"The Hsp90 chaperonin (Hsp82)  was associated with the rAR in both the unliganded (light) and liganded (heavy) receptor state (Fig. 3B). Separately, Hsp70 chaperonin proteins (SSA1, SSA2, SSA4) are associated with rAR primarily in the unliganded receptor state."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/01/20	2016/03/30	rogid:fsxn0EE6wCkb0Y9BsdUtB+FmHAg9606	rogid:u3vFHdbpfo8w7GJh4nHkx/KQRAk559292	intact-crc:0B74C5AB264DCF6D|rigid:emg+CftuSAFsPSJOE4ocRKqjcvs	false	tandem tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P10275	uniprotkb:P22202	intact:EBI-608057|ensembl:ENSP00000363822|ensembl:ENSP00000484033|uniprotkb:A2RUN2|uniprotkb:B1AKD7|uniprotkb:Q9UD95|intact:EBI-11476138|uniprotkb:A0A0B4J1T2|uniprotkb:C0JKD3|uniprotkb:C0JKD4|uniprotkb:E7EVX6	intact:EBI-8621|uniprotkb:D3DM10|ensemblfungi:YER103W	psi-mi:andr_human(display_long)|uniprotkb:Dihydrotestosterone receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 4(gene name synonym)|uniprotkb:AR(gene name)|psi-mi:AR(display_short)|uniprotkb:DHTR(gene name synonym)|uniprotkb:NR3C4(gene name synonym)	psi-mi:hsp74_yeast(display_long)|uniprotkb:YER103W(locus name)|uniprotkb:SSA4(gene name)|psi-mi:SSA4(display_short)	psi-mi:"MI:0030"(cross-linking study)	Austin et al. (2012)	pubmed:22116683|imex:IM-16617	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327763|imex:IM-16617-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169083(gene)|ensembl:ENST00000374690(transcript)|ensembl:ENST00000612452(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005497"(androgen binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045720"(negative regulation of integrin biosynthetic process)|go:"GO:0045726"(positive regulation of integrin biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048638"(regulation of developmental growth)|go:"GO:0048645"(animal organ formation)|go:"GO:0048808"(male genitalia morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0060520"(activation of prostate induction by androgen receptor signaling pathway)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070974"(POU domain binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001103(Androgen receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10275|rcsb pdb:1E3G|rcsb pdb:1GS4|rcsb pdb:1T5Z|rcsb pdb:1T63|rcsb pdb:1T65|rcsb pdb:1XJ7|rcsb pdb:1XOW|rcsb pdb:1XQ3|rcsb pdb:1Z95|rcsb pdb:2AM9|rcsb pdb:2AMA|rcsb pdb:2AMB|rcsb pdb:2AO6|rcsb pdb:2AX6|rcsb pdb:2AX7|rcsb pdb:2AX8|rcsb pdb:2AX9|rcsb pdb:2AXA|rcsb pdb:2HVC|rcsb pdb:2OZ7|rcsb pdb:2PIO|rcsb pdb:2PIP|rcsb pdb:2PIQ|rcsb pdb:2PIR|rcsb pdb:2PIT|rcsb pdb:2PIU|rcsb pdb:2PIV|rcsb pdb:2PIW|rcsb pdb:2PIX|rcsb pdb:2PKL|rcsb pdb:2PNU|rcsb pdb:2Q7I|rcsb pdb:2Q7J|rcsb pdb:2Q7K|rcsb pdb:2Q7L|rcsb pdb:2YHD|rcsb pdb:2YLO|rcsb pdb:2YLP|rcsb pdb:2YLQ|rcsb pdb:2Z4J|rcsb pdb:3B5R|rcsb pdb:3B65|rcsb pdb:3B66|rcsb pdb:3B67|rcsb pdb:3B68|rcsb pdb:3BTR|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:3RLJ|rcsb pdb:3RLL|rcsb pdb:3V49|rcsb pdb:3V4A|rcsb pdb:3ZQT|rcsb pdb:4HLW|rcsb pdb:4K7A|rcsb pdb:4OEA|rcsb pdb:4OED|rcsb pdb:4OEY|rcsb pdb:4OEZ|rcsb pdb:4OFR|rcsb pdb:4OFU|rcsb pdb:4OGH|rcsb pdb:4OH5|rcsb pdb:4OH6|rcsb pdb:4OHA|rcsb pdb:4OIL|rcsb pdb:4OIU|rcsb pdb:4OJ9|rcsb pdb:4OJB|rcsb pdb:4OK1|rcsb pdb:4OKB|rcsb pdb:4OKT|rcsb pdb:4OKW|rcsb pdb:4OKX|rcsb pdb:4OLM|rcsb pdb:4QL8|rcsb pdb:5CJ6|rcsb pdb:5JJM|rcsb pdb:5T8E|rcsb pdb:5T8J|rcsb pdb:5V8Q|rcsb pdb:5VO4|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-8940973|refseq:NP_000035.2|ensembl:ENSP00000363822|ensembl:ENST00000504326|ensembl:ENSP00000421155|ensembl:ENSP00000484033|refseq:NP_001011645.1|refseq:NP_001334990.1|refseq:NP_001334992.1|refseq:NP_001334993.1|dip:DIP-125N	sgd:S000000905|refseq:NP_011029.3|mint:P22202|dip:DIP-3916N|ensemblfungi:YER103W(gene)|ensemblfungi:YER103W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:3UPV	psi-mi:"MI:0469"(intact)	-	crc64:7A976357AC35C352	figure legend:Fig 3, Supplementary Table 1.|comment:"The Hsp90 chaperonin (Hsp82)  was associated with the rAR in both the unliganded (light) and liganded (heavy) receptor state (Fig. 3B). Separately, Hsp70 chaperonin proteins (SSA1, SSA2, SSA4) are associated with rAR primarily in the unliganded receptor state."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/01/20	2016/03/30	rogid:fsxn0EE6wCkb0Y9BsdUtB+FmHAg9606	rogid:QiL3U6hhfGX8ulZBYuNAL68zI2s559292	intact-crc:0B74C5AB264DCF6D|rigid:emg+CftuSAFsPSJOE4ocRKqjcvs	false	tandem tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)