#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0AEC8	uniprotkb:P0AEC8	intact:EBI-1134683|uniprotkb:P39272|uniprotkb:P76795|uniprotkb:Q2M6H9|ensemblbacteria:AAC77086|ensemblbacteria:BAE78127	intact:EBI-1134683|uniprotkb:P39272|uniprotkb:P76795|uniprotkb:Q2M6H9|ensemblbacteria:AAC77086|ensemblbacteria:BAE78127	psi-mi:dcus_ecoli(display_long)|uniprotkb:yjdH(gene name synonym)|uniprotkb:dcuS(gene name)|psi-mi:dcuS(display_short)|uniprotkb:b4125(locus name)|uniprotkb:JW4086(locus name)|uniprotkb:Fumarate sensor(gene name synonym)	psi-mi:dcus_ecoli(display_long)|uniprotkb:yjdH(gene name synonym)|uniprotkb:dcuS(gene name)|psi-mi:dcuS(display_short)|uniprotkb:b4125(locus name)|uniprotkb:JW4086(locus name)|uniprotkb:Fumarate sensor(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Scheu et al. (2012)	pubmed:22101843|imex:IM-18435	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6417623|mpidb:MPIDB-INT-1768|imex:IM-18435-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418549.1|refseq:WP_001216477.1|ensemblbacteria:AAC77086(transcript)|ensemblbacteria:b4125(gene)|ensemblbacteria:BAE78127(gene)|ensemblbacteria:BAE78127(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009365"(protein histidine kinase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR016120(Signal transduction histidine kinase, sporulation regulator SpoOB)|interpro:IPR029151|interpro:IPR033463|interpro:IPR035965|interpro:IPR036890|interpro:IPR039506|rcsb pdb:1OJG|rcsb pdb:2W0N|rcsb pdb:3BY8|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|dip:DIP-9414N	refseq:NP_418549.1|refseq:WP_001216477.1|ensemblbacteria:AAC77086(transcript)|ensemblbacteria:b4125(gene)|ensemblbacteria:BAE78127(gene)|ensemblbacteria:BAE78127(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009365"(protein histidine kinase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR016120(Signal transduction histidine kinase, sporulation regulator SpoOB)|interpro:IPR029151|interpro:IPR033463|interpro:IPR035965|interpro:IPR036890|interpro:IPR039506|rcsb pdb:1OJG|rcsb pdb:2W0N|rcsb pdb:3BY8|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|dip:DIP-9414N	-	-	-	figure legend:figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:yTPZ36tOTJexHrjFNLuIX0cNUU083333	rogid:yTPZ36tOTJexHrjFNLuIX0cNUU083333	intact-crc:1AB8B998E6721FA0|rigid:DgO5ouJ/8MX8DOWW5hkDLGmmky8	false	cyan fluorescent protein tag:?-?	yellow fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P0AEC8	uniprotkb:P77510	intact:EBI-1134683|uniprotkb:P39272|uniprotkb:P76795|uniprotkb:Q2M6H9|ensemblbacteria:AAC77086|ensemblbacteria:BAE78127	intact:EBI-1119251|uniprotkb:O54338|ensemblbacteria:BAA35255|ensemblbacteria:AAC73720	psi-mi:dcus_ecoli(display_long)|uniprotkb:yjdH(gene name synonym)|uniprotkb:dcuS(gene name)|psi-mi:dcuS(display_short)|uniprotkb:b4125(locus name)|uniprotkb:JW4086(locus name)|uniprotkb:Fumarate sensor(gene name synonym)	psi-mi:dpib_ecoli(display_long)|uniprotkb:ybeP(gene name synonym)|uniprotkb:Sensor histidine kinase CitA(gene name synonym)|uniprotkb:dpiB(gene name)|psi-mi:dpiB(display_short)|uniprotkb:citA(gene name synonym)|uniprotkb:mpdB(gene name synonym)|uniprotkb:b0619(locus name)|uniprotkb:JW0611(locus name)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Scheu et al. (2012)	pubmed:22101843|imex:IM-18435	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6417637|mpidb:MPIDB-INT-1767|imex:IM-18435-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418549.1|refseq:WP_001216477.1|ensemblbacteria:AAC77086(transcript)|ensemblbacteria:b4125(gene)|ensemblbacteria:BAE78127(gene)|ensemblbacteria:BAE78127(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009365"(protein histidine kinase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR016120(Signal transduction histidine kinase, sporulation regulator SpoOB)|interpro:IPR029151|interpro:IPR033463|interpro:IPR035965|interpro:IPR036890|interpro:IPR039506|rcsb pdb:1OJG|rcsb pdb:2W0N|rcsb pdb:3BY8|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|dip:DIP-9414N	interpro:IPR033463|ensemblbacteria:b0619(gene)|ensemblbacteria:BAA35255(gene)|ensemblbacteria:BAA35255(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0018106"(peptidyl-histidine phosphorylation)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0046777"(protein autophosphorylation)|ensemblbacteria:AAC73720(transcript)|refseq:WP_000939767.1|refseq:NP_415152.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR000014(PAS)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR016120(Signal transduction histidine kinase, sporulation regulator SpoOB)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR029151|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036890|interpro:IPR039506	-	-	-	figure legend:figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:yTPZ36tOTJexHrjFNLuIX0cNUU083333	rogid:q0bHcKZra7Jic30tPWtTOtU7uWE83333	intact-crc:A3BCECF92D2C7525|rigid:be+3VPhzAam+DXoF5ByZGn4l9Ko	false	cyan fluorescent protein tag:?-?	yellow fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P0AEC8	uniprotkb:P0AD01	intact:EBI-1134683|uniprotkb:P39272|uniprotkb:P76795|uniprotkb:Q2M6H9|ensemblbacteria:AAC77086|ensemblbacteria:BAE78127	intact:EBI-561565|uniprotkb:P39271|ensemblbacteria:AAC77085|ensemblbacteria:BAE78126|uniprotkb:P76794|uniprotkb:Q2M6I0	psi-mi:dcus_ecoli(display_long)|uniprotkb:yjdH(gene name synonym)|uniprotkb:dcuS(gene name)|psi-mi:dcuS(display_short)|uniprotkb:b4125(locus name)|uniprotkb:JW4086(locus name)|uniprotkb:Fumarate sensor(gene name synonym)	psi-mi:dcur_ecoli(display_long)|uniprotkb:yjdG(gene name synonym)|uniprotkb:dcuR(gene name)|psi-mi:dcuR(display_short)|uniprotkb:b4124(locus name)|uniprotkb:JW4085(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Scheu et al. (2012)	pubmed:22101843|imex:IM-18435	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6417649|mpidb:MPIDB-INT-1770|imex:IM-18435-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418549.1|refseq:WP_001216477.1|ensemblbacteria:AAC77086(transcript)|ensemblbacteria:b4125(gene)|ensemblbacteria:BAE78127(gene)|ensemblbacteria:BAE78127(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009365"(protein histidine kinase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR016120(Signal transduction histidine kinase, sporulation regulator SpoOB)|interpro:IPR029151|interpro:IPR033463|interpro:IPR035965|interpro:IPR036890|interpro:IPR039506|rcsb pdb:1OJG|rcsb pdb:2W0N|rcsb pdb:3BY8|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|dip:DIP-9414N	interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR024187|ensemblbacteria:AAC77085(transcript)|ensemblbacteria:b4124(gene)|ensemblbacteria:BAE78126(gene)|ensemblbacteria:BAE78126(transcript)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_418548.1|refseq:WP_000611288.1|dip:DIP-48032N	-	-	-	figure legend:figure 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:yTPZ36tOTJexHrjFNLuIX0cNUU083333	rogid:yd05SyC7weq2YWrl2OPV3rVQK5Q83333	intact-crc:BD2EC42423626911|rigid:mrZN+D8xWd+rsdnZvdlnRNz05xU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AEC8	uniprotkb:P0AEC8	intact:EBI-1134683|uniprotkb:P39272|uniprotkb:P76795|uniprotkb:Q2M6H9|ensemblbacteria:AAC77086|ensemblbacteria:BAE78127	intact:EBI-1134683|uniprotkb:P39272|uniprotkb:P76795|uniprotkb:Q2M6H9|ensemblbacteria:AAC77086|ensemblbacteria:BAE78127	psi-mi:dcus_ecoli(display_long)|uniprotkb:yjdH(gene name synonym)|uniprotkb:dcuS(gene name)|psi-mi:dcuS(display_short)|uniprotkb:b4125(locus name)|uniprotkb:JW4086(locus name)|uniprotkb:Fumarate sensor(gene name synonym)	psi-mi:dcus_ecoli(display_long)|uniprotkb:yjdH(gene name synonym)|uniprotkb:dcuS(gene name)|psi-mi:dcuS(display_short)|uniprotkb:b4125(locus name)|uniprotkb:JW4086(locus name)|uniprotkb:Fumarate sensor(gene name synonym)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Scheu et al. (2012)	pubmed:22101843|imex:IM-18435	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6417655|mpidb:MPIDB-INT-1769|imex:IM-18435-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418549.1|refseq:WP_001216477.1|ensemblbacteria:AAC77086(transcript)|ensemblbacteria:b4125(gene)|ensemblbacteria:BAE78127(gene)|ensemblbacteria:BAE78127(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009365"(protein histidine kinase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR016120(Signal transduction histidine kinase, sporulation regulator SpoOB)|interpro:IPR029151|interpro:IPR033463|interpro:IPR035965|interpro:IPR036890|interpro:IPR039506|rcsb pdb:1OJG|rcsb pdb:2W0N|rcsb pdb:3BY8|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|dip:DIP-9414N	refseq:NP_418549.1|refseq:WP_001216477.1|ensemblbacteria:AAC77086(transcript)|ensemblbacteria:b4125(gene)|ensemblbacteria:BAE78127(gene)|ensemblbacteria:BAE78127(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009365"(protein histidine kinase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR016120(Signal transduction histidine kinase, sporulation regulator SpoOB)|interpro:IPR029151|interpro:IPR033463|interpro:IPR035965|interpro:IPR036890|interpro:IPR039506|rcsb pdb:1OJG|rcsb pdb:2W0N|rcsb pdb:3BY8|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|dip:DIP-9414N	-	-	-	figure legend:figure 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:yTPZ36tOTJexHrjFNLuIX0cNUU083333	rogid:yTPZ36tOTJexHrjFNLuIX0cNUU083333	intact-crc:567FAD17FA7B744B|rigid:DgO5ouJ/8MX8DOWW5hkDLGmmky8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)