#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P39718 uniprotkb:P29340 intact:EBI-20707|uniprotkb:D6VPG3|ensemblfungi:YAL055W intact:EBI-19784|uniprotkb:D6VUR5|ensemblfungi:YGR133W psi-mi:pex22_yeast(display_long)|uniprotkb:YAL055W(locus name)|uniprotkb:PEX22(gene name)|psi-mi:PEX22(display_short)|uniprotkb:Peroxin-22(gene name synonym) psi-mi:ubcx_yeast(display_long)|uniprotkb:PEX4(gene name)|psi-mi:PEX4(display_short)|uniprotkb:PAS2(gene name synonym)|uniprotkb:UBC10(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Peroxin-4(gene name synonym)|uniprotkb:YGR133W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme PEX4(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Williams et al. (2012) doi:10.1038/emboj.2011.411|pubmed:22085930|imex:IM-17566|mint:MINT-8368508 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7550657|mint:MINT-8368517|imex:IM-17566-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009346.1|sgd:S000000051|ensemblfungi:YAL055W(gene)|ensemblfungi:YAL055W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR038613|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|interpro:IPR024359|dip:DIP-2791N|go:"GO:1902499"(positive regulation of protein autoubiquitination)|mint:MINT-8368520(identity) refseq:NP_011649.1|sgd:S000003365|ensemblfungi:YGR133W(gene)|ensemblfungi:YGR133W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|dip:DIP-4411N|mint:P29340|mint:MINT-8368519(identity) - - - comment:mint|figure legend:f3 t2 f5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/04/18 2014/10/16 rogid:/YiSPg/+qaN+v79lO85js/YeiLg559292 rogid:+rOg4RSLbF0lsoJHgzSe784ckiY559292 intact-crc:72BFC6CE9B7B0C9E|rigid:v7udSaL0FvvGZU1wzUlEUAodJgA false binding-associated region:54-180(MINT-8368526) binding-associated region:15-183(MINT-8368522) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29340 uniprotkb:P39718 intact:EBI-19784|uniprotkb:D6VUR5|ensemblfungi:YGR133W intact:EBI-20707|uniprotkb:D6VPG3|ensemblfungi:YAL055W psi-mi:ubcx_yeast(display_long)|uniprotkb:PEX4(gene name)|psi-mi:PEX4(display_short)|uniprotkb:PAS2(gene name synonym)|uniprotkb:UBC10(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Peroxin-4(gene name synonym)|uniprotkb:YGR133W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme PEX4(gene name synonym) psi-mi:pex22_yeast(display_long)|uniprotkb:YAL055W(locus name)|uniprotkb:PEX22(gene name)|psi-mi:PEX22(display_short)|uniprotkb:Peroxin-22(gene name synonym) psi-mi:"MI:0018"(two hybrid) Williams et al. (2012) doi:10.1038/emboj.2011.411|pubmed:22085930|imex:IM-17566|mint:MINT-8368508 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7550713|mint:MINT-8368552|imex:IM-17566-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011649.1|sgd:S000003365|ensemblfungi:YGR133W(gene)|ensemblfungi:YGR133W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|dip:DIP-4411N|mint:P29340|mint:MINT-8368554(identity) refseq:NP_009346.1|sgd:S000000051|ensemblfungi:YAL055W(gene)|ensemblfungi:YAL055W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR038613|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|interpro:IPR024359|dip:DIP-2791N|go:"GO:1902499"(positive regulation of protein autoubiquitination)|mint:MINT-8368558(identity) - - - figure legend:st1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/04/18 2014/10/16 rogid:+rOg4RSLbF0lsoJHgzSe784ckiY559292 rogid:/YiSPg/+qaN+v79lO85js/YeiLg559292 intact-crc:4C490D57A05AB8B9|rigid:v7udSaL0FvvGZU1wzUlEUAodJgA false fusion protein:?-?(MINT-8368564)|binding-associated region:15-183(MINT-8368555) binding-associated region:54-180(MINT-8368559)|fusion protein:?-?(MINT-8368567) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39718 uniprotkb:P29340 intact:EBI-20707|uniprotkb:D6VPG3|ensemblfungi:YAL055W intact:EBI-19784|uniprotkb:D6VUR5|ensemblfungi:YGR133W psi-mi:pex22_yeast(display_long)|uniprotkb:YAL055W(locus name)|uniprotkb:PEX22(gene name)|psi-mi:PEX22(display_short)|uniprotkb:Peroxin-22(gene name synonym) psi-mi:ubcx_yeast(display_long)|uniprotkb:PEX4(gene name)|psi-mi:PEX4(display_short)|uniprotkb:PAS2(gene name synonym)|uniprotkb:UBC10(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Peroxin-4(gene name synonym)|uniprotkb:YGR133W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme PEX4(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Williams et al. (2012) doi:10.1038/emboj.2011.411|pubmed:22085930|imex:IM-17566|mint:MINT-8368508 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7550771|mint:MINT-8368571|imex:IM-17566-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009346.1|sgd:S000000051|ensemblfungi:YAL055W(gene)|ensemblfungi:YAL055W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR038613|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|interpro:IPR024359|dip:DIP-2791N|go:"GO:1902499"(positive regulation of protein autoubiquitination)|mint:MINT-8368577(identity) refseq:NP_011649.1|sgd:S000003365|ensemblfungi:YGR133W(gene)|ensemblfungi:YGR133W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|dip:DIP-4411N|mint:P29340|mint:MINT-8368573(identity) - - - comment:mint|figure legend:t1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.0x10^-9(molar) 2012/04/18 2014/10/16 rogid:/YiSPg/+qaN+v79lO85js/YeiLg559292 rogid:+rOg4RSLbF0lsoJHgzSe784ckiY559292 intact-crc:0795F1BDE052485E|rigid:v7udSaL0FvvGZU1wzUlEUAodJgA false binding-associated region:54-180(MINT-8368578) mutation disrupting interaction:172-172(MINT-8368583)|binding-associated region:15-183(MINT-8368574) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39718 uniprotkb:P29340 intact:EBI-20707|uniprotkb:D6VPG3|ensemblfungi:YAL055W intact:EBI-19784|uniprotkb:D6VUR5|ensemblfungi:YGR133W psi-mi:pex22_yeast(display_long)|uniprotkb:YAL055W(locus name)|uniprotkb:PEX22(gene name)|psi-mi:PEX22(display_short)|uniprotkb:Peroxin-22(gene name synonym) psi-mi:ubcx_yeast(display_long)|uniprotkb:PEX4(gene name)|psi-mi:PEX4(display_short)|uniprotkb:PAS2(gene name synonym)|uniprotkb:UBC10(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Peroxin-4(gene name synonym)|uniprotkb:YGR133W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme PEX4(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Williams et al. (2012) doi:10.1038/emboj.2011.411|pubmed:22085930|imex:IM-17566|mint:MINT-8368508 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7550810|mint:MINT-8368590|imex:IM-17566-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009346.1|sgd:S000000051|ensemblfungi:YAL055W(gene)|ensemblfungi:YAL055W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR038613|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|interpro:IPR024359|dip:DIP-2791N|go:"GO:1902499"(positive regulation of protein autoubiquitination)|mint:MINT-8368599(identity) refseq:NP_011649.1|sgd:S000003365|ensemblfungi:YGR133W(gene)|ensemblfungi:YGR133W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|dip:DIP-4411N|mint:P29340|mint:MINT-8368593(identity) - - - comment:mint|figure legend:t1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.5x10^-8(molar) 2012/04/18 2014/10/16 rogid:/YiSPg/+qaN+v79lO85js/YeiLg559292 rogid:+rOg4RSLbF0lsoJHgzSe784ckiY559292 intact-crc:EFA32498E7F6FA9D|rigid:v7udSaL0FvvGZU1wzUlEUAodJgA false binding-associated region:54-180(MINT-8368600) mutation decreasing interaction:172-172(MINT-8368594)|binding-associated region:15-183(MINT-8368596) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29340 uniprotkb:P39718 intact:EBI-19784|uniprotkb:D6VUR5|ensemblfungi:YGR133W intact:EBI-20707|uniprotkb:D6VPG3|ensemblfungi:YAL055W psi-mi:ubcx_yeast(display_long)|uniprotkb:PEX4(gene name)|psi-mi:PEX4(display_short)|uniprotkb:PAS2(gene name synonym)|uniprotkb:UBC10(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Peroxin-4(gene name synonym)|uniprotkb:YGR133W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme PEX4(gene name synonym) psi-mi:pex22_yeast(display_long)|uniprotkb:YAL055W(locus name)|uniprotkb:PEX22(gene name)|psi-mi:PEX22(display_short)|uniprotkb:Peroxin-22(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Williams et al. (2012) doi:10.1038/emboj.2011.411|pubmed:22085930|imex:IM-17566|mint:MINT-8368508 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7550888|mint:MINT-8368607|imex:IM-17566-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011649.1|sgd:S000003365|ensemblfungi:YGR133W(gene)|ensemblfungi:YGR133W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|dip:DIP-4411N|mint:P29340|mint:MINT-8368610(identity) refseq:NP_009346.1|sgd:S000000051|ensemblfungi:YAL055W(gene)|ensemblfungi:YAL055W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR038613|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|interpro:IPR024359|dip:DIP-2791N|go:"GO:1902499"(positive regulation of protein autoubiquitination)|mint:MINT-8368616(identity) - - - comment:mint|figure legend:t1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.84x10^-8(molar) 2012/04/18 2014/10/16 rogid:+rOg4RSLbF0lsoJHgzSe784ckiY559292 rogid:/YiSPg/+qaN+v79lO85js/YeiLg559292 intact-crc:270B2F6D091358DE|rigid:v7udSaL0FvvGZU1wzUlEUAodJgA false binding-associated region:15-183(MINT-8368613) mutation decreasing interaction:133-133(MINT-8368622)|binding-associated region:54-180(MINT-8368617) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39718 uniprotkb:P29340 intact:EBI-20707|uniprotkb:D6VPG3|ensemblfungi:YAL055W intact:EBI-19784|uniprotkb:D6VUR5|ensemblfungi:YGR133W psi-mi:pex22_yeast(display_long)|uniprotkb:YAL055W(locus name)|uniprotkb:PEX22(gene name)|psi-mi:PEX22(display_short)|uniprotkb:Peroxin-22(gene name synonym) psi-mi:ubcx_yeast(display_long)|uniprotkb:PEX4(gene name)|psi-mi:PEX4(display_short)|uniprotkb:PAS2(gene name synonym)|uniprotkb:UBC10(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Peroxin-4(gene name synonym)|uniprotkb:YGR133W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme PEX4(gene name synonym) psi-mi:"MI:0016"(circular dichroism) Williams et al. (2012) doi:10.1038/emboj.2011.411|pubmed:22085930|imex:IM-17566|mint:MINT-8368508 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7550938|mint:MINT-8368627|imex:IM-17566-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009346.1|sgd:S000000051|ensemblfungi:YAL055W(gene)|ensemblfungi:YAL055W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR038613|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|interpro:IPR024359|dip:DIP-2791N|go:"GO:1902499"(positive regulation of protein autoubiquitination)|mint:MINT-8368634(identity) refseq:NP_011649.1|sgd:S000003365|ensemblfungi:YGR133W(gene)|ensemblfungi:YGR133W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|dip:DIP-4411N|mint:P29340|mint:MINT-8368630(identity) - - - comment:mint|figure legend:sf5 st2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/04/18 2014/10/16 rogid:/YiSPg/+qaN+v79lO85js/YeiLg559292 rogid:+rOg4RSLbF0lsoJHgzSe784ckiY559292 intact-crc:9260F0AE81D86D1D|rigid:v7udSaL0FvvGZU1wzUlEUAodJgA false binding-associated region:54-180(MINT-8368637) binding-associated region:15-183(MINT-8368631) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29340 uniprotkb:P39718 intact:EBI-19784|uniprotkb:D6VUR5|ensemblfungi:YGR133W intact:EBI-20707|uniprotkb:D6VPG3|ensemblfungi:YAL055W psi-mi:ubcx_yeast(display_long)|uniprotkb:PEX4(gene name)|psi-mi:PEX4(display_short)|uniprotkb:PAS2(gene name synonym)|uniprotkb:UBC10(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Peroxin-4(gene name synonym)|uniprotkb:YGR133W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme PEX4(gene name synonym) psi-mi:pex22_yeast(display_long)|uniprotkb:YAL055W(locus name)|uniprotkb:PEX22(gene name)|psi-mi:PEX22(display_short)|uniprotkb:Peroxin-22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Williams et al. (2012) doi:10.1038/emboj.2011.411|pubmed:22085930|imex:IM-17566|mint:MINT-8368508 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7550983|mint:MINT-8368659|imex:IM-17566-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011649.1|sgd:S000003365|ensemblfungi:YGR133W(gene)|ensemblfungi:YGR133W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|dip:DIP-4411N|mint:P29340|mint:MINT-8368661(identity) refseq:NP_009346.1|sgd:S000000051|ensemblfungi:YAL055W(gene)|ensemblfungi:YAL055W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR038613|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|interpro:IPR024359|dip:DIP-2791N|go:"GO:1902499"(positive regulation of protein autoubiquitination)|mint:MINT-8368667(identity) - - - figure legend:f7b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/04/18 2014/10/16 rogid:+rOg4RSLbF0lsoJHgzSe784ckiY559292 rogid:/YiSPg/+qaN+v79lO85js/YeiLg559292 intact-crc:EC5F8D32EAEAAB08|rigid:v7udSaL0FvvGZU1wzUlEUAodJgA false flag tag:?-?(MINT-8368675)|mutation disrupting interaction:172-172(MINT-8368662) binding-associated region:54-180(MINT-8368668)|ha tag:?-?(MINT-8368678) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P29340 uniprotkb:P39718 intact:EBI-19784|uniprotkb:D6VUR5|ensemblfungi:YGR133W intact:EBI-20707|uniprotkb:D6VPG3|ensemblfungi:YAL055W psi-mi:ubcx_yeast(display_long)|uniprotkb:PEX4(gene name)|psi-mi:PEX4(display_short)|uniprotkb:PAS2(gene name synonym)|uniprotkb:UBC10(gene name synonym)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Peroxin-4(gene name synonym)|uniprotkb:YGR133W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme PEX4(gene name synonym) psi-mi:pex22_yeast(display_long)|uniprotkb:YAL055W(locus name)|uniprotkb:PEX22(gene name)|psi-mi:PEX22(display_short)|uniprotkb:Peroxin-22(gene name synonym) psi-mi:"MI:0276"(blue native page) Williams et al. (2012) doi:10.1038/emboj.2011.411|pubmed:22085930|imex:IM-17566|mint:MINT-8368508 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7551035|mint:MINT-8368644|imex:IM-17566-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011649.1|sgd:S000003365|ensemblfungi:YGR133W(gene)|ensemblfungi:YGR133W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|dip:DIP-4411N|mint:P29340|mint:MINT-8368646(identity) refseq:NP_009346.1|sgd:S000000051|ensemblfungi:YAL055W(gene)|ensemblfungi:YAL055W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR038613|rcsb pdb:2Y9M|rcsb pdb:2Y9P|rcsb pdb:4BWF|interpro:IPR024359|dip:DIP-2791N|go:"GO:1902499"(positive regulation of protein autoubiquitination)|mint:MINT-8368650(identity) - - - figure legend:f6a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/04/18 2014/10/16 rogid:+rOg4RSLbF0lsoJHgzSe784ckiY559292 rogid:/YiSPg/+qaN+v79lO85js/YeiLg559292 intact-crc:66016F52127A34C8|rigid:v7udSaL0FvvGZU1wzUlEUAodJgA false mutation disrupting interaction:172-172(MINT-8368656)|binding-associated region:15-183(MINT-8368647) binding-associated region:54-180(MINT-8368651) - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)