#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O94925 uniprotkb:O94925 intact:EBI-1043737|uniprotkb:Q9UL05|uniprotkb:Q9UL06|uniprotkb:Q9UL07|uniprotkb:Q9UN40|ensembl:ENSP00000317379 intact:EBI-1043737|uniprotkb:Q9UL05|uniprotkb:Q9UL06|uniprotkb:Q9UL07|uniprotkb:Q9UN40|ensembl:ENSP00000317379 psi-mi:glsk_human(display_long)|uniprotkb:GLS(gene name)|psi-mi:GLS(display_short)|uniprotkb:GLS1(gene name synonym)|uniprotkb:KIAA0838(gene name synonym)|uniprotkb:L-glutamine amidohydrolase(gene name synonym)|uniprotkb:K-glutaminase(gene name synonym) psi-mi:glsk_human(display_long)|uniprotkb:GLS(gene name)|psi-mi:GLS(display_short)|uniprotkb:GLS1(gene name synonym)|uniprotkb:KIAA0838(gene name synonym)|uniprotkb:L-glutamine amidohydrolase(gene name synonym)|uniprotkb:K-glutaminase(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) DeLaBarre et al. (2011) pubmed:22049910 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-6094965|pdbe:3uo9|pdbe:3unw - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243239.1|refseq:NP_055720.3|dip:DIP-50591N|ensembl:ENSG00000115419(gene)|ensembl:ENST00000320717(transcript)|go:"GO:0001967"(suckling behavior)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0004359"(glutaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0090461"(glutamate homeostasis)|interpro:IPR002110(Ankyrin)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR041541|mint:O94925|rcsb pdb:3CZD|rcsb pdb:3UNW|rcsb pdb:3UO9|rcsb pdb:3VOY|rcsb pdb:3VOZ|rcsb pdb:3VP0|rcsb pdb:3VP1|rcsb pdb:3VP2|rcsb pdb:3VP3|rcsb pdb:3VP4|rcsb pdb:5D3O|rcsb pdb:5FI2|rcsb pdb:5FI6|rcsb pdb:5FI7|rcsb pdb:5HL1|rcsb pdb:5I94|rcsb pdb:5JYO|rcsb pdb:5JYP|rcsb pdb:5U0I|rcsb pdb:5U0J|rcsb pdb:5UQE|rcsb pdb:5WJ6|rcsb pdb:6LOX|rcsb pdb:6UJG|rcsb pdb:6UJM|rcsb pdb:6UK6|rcsb pdb:6UKB|rcsb pdb:4O7D|rcsb pdb:6UL9|rcsb pdb:6ULA|rcsb pdb:6UMC|rcsb pdb:6UMD|rcsb pdb:6UME|rcsb pdb:6UMF|reactome:R-HSA-210500|reactome:R-HSA-5628897|reactome:R-HSA-8964539|rcsb pdb:6ULJ refseq:NP_001243239.1|refseq:NP_055720.3|dip:DIP-50591N|ensembl:ENSG00000115419(gene)|ensembl:ENST00000320717(transcript)|go:"GO:0001967"(suckling behavior)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0004359"(glutaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0090461"(glutamate homeostasis)|interpro:IPR002110(Ankyrin)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR041541|mint:O94925|rcsb pdb:3CZD|rcsb pdb:3UNW|rcsb pdb:3UO9|rcsb pdb:3VOY|rcsb pdb:3VOZ|rcsb pdb:3VP0|rcsb pdb:3VP1|rcsb pdb:3VP2|rcsb pdb:3VP3|rcsb pdb:3VP4|rcsb pdb:5D3O|rcsb pdb:5FI2|rcsb pdb:5FI6|rcsb pdb:5FI7|rcsb pdb:5HL1|rcsb pdb:5I94|rcsb pdb:5JYO|rcsb pdb:5JYP|rcsb pdb:5U0I|rcsb pdb:5U0J|rcsb pdb:5UQE|rcsb pdb:5WJ6|rcsb pdb:6LOX|rcsb pdb:6UJG|rcsb pdb:6UJM|rcsb pdb:6UK6|rcsb pdb:6UKB|rcsb pdb:4O7D|rcsb pdb:6UL9|rcsb pdb:6ULA|rcsb pdb:6UMC|rcsb pdb:6UMD|rcsb pdb:6UME|rcsb pdb:6UMF|reactome:R-HSA-210500|reactome:R-HSA-5628897|reactome:R-HSA-8964539|rcsb pdb:6ULJ - - - figure legend:fig 2|3d-r-factors:R = 0.2 Rworking = 0.19 Rfree = 0.25 for 3uo9 Rworking = 0.23 Rfree = 0.26 for 3unw|3d-resolution:2.3 Å for 3uo9 2.56 A for 3unw|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/04/17 2014/10/16 rogid:IV2jY1Qj63eTVPmTndDavjoUM2w9606 rogid:IV2jY1Qj63eTVPmTndDavjoUM2w9606 intact-crc:C8C45A376742D918|rigid:5ZxVASa1unOMdzofeqMu9kSwX5g false sufficient binding region:71-598 sufficient binding region:71-598 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)