#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8K4C5 uniprotkb:Q60943 intact:EBI-5324374|uniprotkb:A6H6F0 intact:EBI-5324362|ensembl:ENSMUSP00000002976 psi-mi:il17c_mouse(display_long)|uniprotkb:Il17c(gene name)|psi-mi:Il17c(display_short)|uniprotkb:Cytokine CX2(gene name synonym) psi-mi:i17ra_mouse(display_long)|uniprotkb:Il17ra(gene name)|psi-mi:Il17ra(display_short)|uniprotkb:Il17r(gene name synonym) psi-mi:"MI:0096"(pull down) Song et al. (2011) pubmed:21993849|imex:IM-16638 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-5324373|imex:IM-16638-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|refseq:NP_665833.3|interpro:IPR020440|interpro:IPR010345(Interleukin-17)|interpro:IPR029034 ensembl:ENSMUSG00000002897(gene)|ensembl:ENSMUST00000002976(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030368"(interleukin-17 receptor activity)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0072537"(fibroblast activation)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:2000340"("positive regulation of chemokine (C-X-C motif) ligand 1 production")|interpro:IPR013568(SEFIR)|interpro:IPR032356|interpro:IPR038683|interpro:IPR039465|interpro:IPR043046|go:"GO:0050832"(defense response to fungus)|refseq:NP_032385.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5A, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/01/08 2014/10/16 rogid:/Ay+jxooJF2MrC/SfSptlYE/0Zo10090 rogid:M4wYmAZfMU/ycqoqZHjlI8wq/3M10090 intact-crc:5B9EBB6761E64058|rigid:y+l5w06h9mj3HHJ8SqU7VDM42II false glutathione s tranferase tag:?-? sufficient binding region:32..32-322..322|ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BH06 uniprotkb:Q8K4C5 intact:EBI-5324405|ensembl:ENSMUSP00000062103|uniprotkb:Q3I5F0|uniprotkb:Q6NSU9|uniprotkb:Q8C5D0|uniprotkb:Q8K4C1|uniprotkb:Q8R335 intact:EBI-5324374|uniprotkb:A6H6F0 psi-mi:i17re_mouse(display_long)|uniprotkb:Il17re(gene name)|psi-mi:Il17re(display_short) psi-mi:il17c_mouse(display_long)|uniprotkb:Il17c(gene name)|psi-mi:Il17c(display_short)|uniprotkb:Cytokine CX2(gene name synonym) psi-mi:"MI:0096"(pull down) Song et al. (2011) pubmed:21993849|imex:IM-16638 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-5324395|imex:IM-16638-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000043088(gene)|ensembl:ENSMUST00000058548(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030368"(interleukin-17 receptor activity)|interpro:IPR013568(SEFIR)|interpro:IPR027841|interpro:IPR039465|refseq:NP_001029201.1|refseq:NP_001029203.1|refseq:NP_665825.2 go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|refseq:NP_665833.3|interpro:IPR020440|interpro:IPR010345(Interleukin-17)|interpro:IPR029034 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5A, 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/01/08 2014/10/16 rogid:qnthfZB/79TTcvGcZhlBjHoPLAc10090 rogid:/Ay+jxooJF2MrC/SfSptlYE/0Zo10090 intact-crc:639200DD89A3A2A1|rigid:0QDICuzx8vn+l7znk3WA9+nn8QA false sufficient binding region:24..24-414..414|ha tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8VHH8 uniprotkb:Q9JIP3 intact:EBI-5324521|ensembl:ENSMUSP00000039641 intact:EBI-5324535|ensembl:ENSMUSP00000016110|uniprotkb:Q9JIP2 psi-mi:q8vhh8_mouse(display_long)|uniprotkb:Il25(gene name)|psi-mi:Il25(display_short)|uniprotkb:Il17e(gene name synonym) psi-mi:i17rb_mouse(display_long)|uniprotkb:Il17rb(gene name)|psi-mi:Il17rb(display_short)|uniprotkb:Evi27(gene name synonym)|uniprotkb:Il17br(gene name synonym)|uniprotkb:IL-17 receptor homolog 1(gene name synonym)|uniprotkb:Interleukin-17B receptor(gene name synonym) psi-mi:"MI:0096"(pull down) Song et al. (2011) pubmed:21993849|imex:IM-16638 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-5324513|imex:IM-16638-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000037863(transcript)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0009620"(response to fungus)|go:"GO:0009624"(response to nematode)|go:"GO:0030222"(eosinophil differentiation)|go:"GO:0030380"(interleukin-17E receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR010345(Interleukin-17)|interpro:IPR029034|ensembl:ENSMUSG00000040770(gene)|refseq:NP_542767.1 ensembl:ENSMUSG00000015966(gene)|ensembl:ENSMUST00000016110(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0030368"(interleukin-17 receptor activity)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0034451"(centriolar satellite)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0072686"(mitotic spindle)|interpro:IPR013568(SEFIR)|interpro:IPR032356|interpro:IPR038683|go:"GO:0005737"(cytoplasm)|interpro:IPR039465|interpro:IPR043046|rcsb pdb:3VBC|refseq:NP_062529.2 psi-mi:"MI:0469"(intact) - - figure legend:Fig. S7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/01/08 2014/10/16 rogid:ajicgLBwsDtSMmbbBlPvAlB4g/U10090 rogid:YhbQr1jpoe5HPT2KfMqLRhZvgDI10090 intact-crc:88DD0185214AB3BE|rigid:kNCftQaWNVYtf9K9DDVjeeDBw/o false glutathione s tranferase tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7TNI7 uniprotkb:Q8K4C2 intact:EBI-5324490|ensembl:ENSMUSP00000046960|uniprotkb:Q8K4C3 intact:EBI-5324469|uniprotkb:G3X9C0|uniprotkb:Q99J43 psi-mi:il17f_mouse(display_long)|uniprotkb:Il17f(gene name)|psi-mi:Il17f(display_short) psi-mi:i17rc_mouse(display_long)|uniprotkb:Il17rc(gene name)|psi-mi:Il17rc(display_short)|uniprotkb:Interleukin-17 receptor-like protein(gene name synonym)|uniprotkb:ZcytoR14(gene name synonym) psi-mi:"MI:0096"(pull down) Song et al. (2011) pubmed:21993849|imex:IM-16638 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-5324505|imex:IM-16638-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000041872(gene)|ensembl:ENSMUST00000039046(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032645"(regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032663"(regulation of interleukin-2 production)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032761"(positive regulation of lymphotoxin A production)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051216"(cartilage development)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:2000340"("positive regulation of chemokine (C-X-C motif) ligand 1 production")|interpro:IPR010345(Interleukin-17)|interpro:IPR020440|interpro:IPR029034|refseq:NP_665855.2|refseq:XP_006495586.1 go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030368"(interleukin-17 receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0050832"(defense response to fungus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|refseq:XP_006505728.1|refseq:XP_006505729.1|interpro:IPR013568(SEFIR)|refseq:NP_598920.3|refseq:NP_849273.1|interpro:IPR027841|interpro:IPR039465 psi-mi:"MI:0469"(intact) - - figure legend:Fig. S7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/01/08 2016/03/30 rogid:8wxudJ4tp+JC2oP1RmfkNbld/UQ10090 rogid:6BEmhXHwxuD0w/7OEjEn6h6KcU010090 intact-crc:B2032266ADA9147F|rigid:4QLn9efsJoDdo2iUju05fGpFUYg false glutathione s tranferase tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q62386 uniprotkb:Q8K4C2 intact:EBI-5324442|ensembl:ENSMUSP00000027061|uniprotkb:Q60971 intact:EBI-5324469|uniprotkb:G3X9C0|uniprotkb:Q99J43 psi-mi:il17_mouse(display_long)|uniprotkb:Il17a(gene name)|psi-mi:Il17a(display_short)|uniprotkb:Ctla8(gene name synonym)|uniprotkb:Il17(gene name synonym)|uniprotkb:Cytotoxic T-lymphocyte-associated antigen 8(gene name synonym) psi-mi:i17rc_mouse(display_long)|uniprotkb:Il17rc(gene name)|psi-mi:Il17rc(display_short)|uniprotkb:Interleukin-17 receptor-like protein(gene name synonym)|uniprotkb:ZcytoR14(gene name synonym) psi-mi:"MI:0096"(pull down) Song et al. (2011) pubmed:21993849|imex:IM-16638 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-5324461|imex:IM-16638-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025929(gene)|ensembl:ENSMUST00000027061(transcript)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032739"(positive regulation of interleukin-16 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072537"(fibroblast activation)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:0097530"(granulocyte migration)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:2000340"("positive regulation of chemokine (C-X-C motif) ligand 1 production")|interpro:IPR010345(Interleukin-17)|interpro:IPR020440|interpro:IPR029034|refseq:NP_034682.1 go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030368"(interleukin-17 receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0050832"(defense response to fungus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|refseq:XP_006505728.1|refseq:XP_006505729.1|interpro:IPR013568(SEFIR)|refseq:NP_598920.3|refseq:NP_849273.1|interpro:IPR027841|interpro:IPR039465 psi-mi:"MI:0469"(intact) - - figure legend:Fig. S7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/01/08 2016/03/30 rogid:1hgHbpFblAVIuvj04t3pHZ0+jdg10090 rogid:6BEmhXHwxuD0w/7OEjEn6h6KcU010090 intact-crc:697B61DC12D00AD5|rigid:v8Uwlkwyk66IOL0VLYCnukxh87c false glutathione s tranferase tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q62386 uniprotkb:Q60943 intact:EBI-5324442|ensembl:ENSMUSP00000027061|uniprotkb:Q60971 intact:EBI-5324362|ensembl:ENSMUSP00000002976 psi-mi:il17_mouse(display_long)|uniprotkb:Il17a(gene name)|psi-mi:Il17a(display_short)|uniprotkb:Ctla8(gene name synonym)|uniprotkb:Il17(gene name synonym)|uniprotkb:Cytotoxic T-lymphocyte-associated antigen 8(gene name synonym) psi-mi:i17ra_mouse(display_long)|uniprotkb:Il17ra(gene name)|psi-mi:Il17ra(display_short)|uniprotkb:Il17r(gene name synonym) psi-mi:"MI:0096"(pull down) Song et al. (2011) pubmed:21993849|imex:IM-16638 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-5324432|imex:IM-16638-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025929(gene)|ensembl:ENSMUST00000027061(transcript)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032739"(positive regulation of interleukin-16 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072537"(fibroblast activation)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:0097530"(granulocyte migration)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:2000340"("positive regulation of chemokine (C-X-C motif) ligand 1 production")|interpro:IPR010345(Interleukin-17)|interpro:IPR020440|interpro:IPR029034|refseq:NP_034682.1 ensembl:ENSMUSG00000002897(gene)|ensembl:ENSMUST00000002976(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030368"(interleukin-17 receptor activity)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0072537"(fibroblast activation)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:2000340"("positive regulation of chemokine (C-X-C motif) ligand 1 production")|interpro:IPR013568(SEFIR)|interpro:IPR032356|interpro:IPR038683|interpro:IPR039465|interpro:IPR043046|go:"GO:0050832"(defense response to fungus)|refseq:NP_032385.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5D, S7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/01/08 2014/10/16 rogid:1hgHbpFblAVIuvj04t3pHZ0+jdg10090 rogid:M4wYmAZfMU/ycqoqZHjlI8wq/3M10090 intact-crc:308A1F12C761E130|rigid:nT/gjAbilIArBNsbO4Oma4Ujq3M false glutathione s tranferase tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q60943 uniprotkb:Q7TNI7 intact:EBI-5324362|ensembl:ENSMUSP00000002976 intact:EBI-5324490|ensembl:ENSMUSP00000046960|uniprotkb:Q8K4C3 psi-mi:i17ra_mouse(display_long)|uniprotkb:Il17ra(gene name)|psi-mi:Il17ra(display_short)|uniprotkb:Il17r(gene name synonym) psi-mi:il17f_mouse(display_long)|uniprotkb:Il17f(gene name)|psi-mi:Il17f(display_short) psi-mi:"MI:0096"(pull down) Song et al. (2011) pubmed:21993849|imex:IM-16638 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-5324482|imex:IM-16638-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000002897(gene)|ensembl:ENSMUST00000002976(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030368"(interleukin-17 receptor activity)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0072537"(fibroblast activation)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:2000340"("positive regulation of chemokine (C-X-C motif) ligand 1 production")|interpro:IPR013568(SEFIR)|interpro:IPR032356|interpro:IPR038683|interpro:IPR039465|interpro:IPR043046|go:"GO:0050832"(defense response to fungus)|refseq:NP_032385.1 ensembl:ENSMUSG00000041872(gene)|ensembl:ENSMUST00000039046(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002225"(positive regulation of antimicrobial peptide production)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032645"(regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032663"(regulation of interleukin-2 production)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032761"(positive regulation of lymphotoxin A production)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051216"(cartilage development)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:2000340"("positive regulation of chemokine (C-X-C motif) ligand 1 production")|interpro:IPR010345(Interleukin-17)|interpro:IPR020440|interpro:IPR029034|refseq:NP_665855.2|refseq:XP_006495586.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. S7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/01/08 2014/10/16 rogid:M4wYmAZfMU/ycqoqZHjlI8wq/3M10090 rogid:8wxudJ4tp+JC2oP1RmfkNbld/UQ10090 intact-crc:F8B14A2FD56E43BC|rigid:qjek6YAG56mtN78ASOnww0/n9WM false ha tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BH06 uniprotkb:Q60943 intact:EBI-5324405|ensembl:ENSMUSP00000062103|uniprotkb:Q3I5F0|uniprotkb:Q6NSU9|uniprotkb:Q8C5D0|uniprotkb:Q8K4C1|uniprotkb:Q8R335 intact:EBI-5324362|ensembl:ENSMUSP00000002976 psi-mi:i17re_mouse(display_long)|uniprotkb:Il17re(gene name)|psi-mi:Il17re(display_short) psi-mi:i17ra_mouse(display_long)|uniprotkb:Il17ra(gene name)|psi-mi:Il17ra(display_short)|uniprotkb:Il17r(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Song et al. (2011) pubmed:21993849|imex:IM-16638 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-5324563|imex:IM-16638-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000043088(gene)|ensembl:ENSMUST00000058548(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030368"(interleukin-17 receptor activity)|interpro:IPR013568(SEFIR)|interpro:IPR027841|interpro:IPR039465|refseq:NP_001029201.1|refseq:NP_001029203.1|refseq:NP_665825.2 ensembl:ENSMUSG00000002897(gene)|ensembl:ENSMUST00000002976(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0009615"(response to virus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030368"(interleukin-17 receptor activity)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0072537"(fibroblast activation)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:2000340"("positive regulation of chemokine (C-X-C motif) ligand 1 production")|interpro:IPR013568(SEFIR)|interpro:IPR032356|interpro:IPR038683|interpro:IPR039465|interpro:IPR043046|go:"GO:0050832"(defense response to fungus)|refseq:NP_032385.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/01/08 2014/10/16 rogid:qnthfZB/79TTcvGcZhlBjHoPLAc10090 rogid:M4wYmAZfMU/ycqoqZHjlI8wq/3M10090 intact-crc:A2EA978FB4668FD0|rigid:9gAWhSj3o94Bs5fNnZP/ldqnjrY false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)