#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P20794	uniprotkb:Q8IZL9	intact:EBI-3911321|uniprotkb:Q9NUH7|uniprotkb:F1T0K6|uniprotkb:G1FL29|uniprotkb:Q547D0|ensembl:ENSP00000313021|ensembl:ENSP00000476067	intact:EBI-6128565|uniprotkb:A2A389|uniprotkb:A2A390|uniprotkb:B4DQX1|uniprotkb:Q5EDC4|uniprotkb:Q5VYW1|uniprotkb:Q9BUF4|uniprotkb:O95137|ensembl:ENSP00000322343	psi-mi:mak_human(display_long)|uniprotkb:MAK(gene name)|psi-mi:MAK(display_short)|uniprotkb:Male germ cell-associated kinase(gene name synonym)	psi-mi:cdk20_human(display_long)|uniprotkb:CDK20(gene name)|psi-mi:CDK20(display_short)|uniprotkb:CCRK(gene name synonym)|uniprotkb:CDCH(gene name synonym)|uniprotkb:CDK-activating kinase p42(gene name synonym)|uniprotkb:Cell cycle-related kinase(gene name synonym)|uniprotkb:Cell division protein kinase 20(gene name synonym)|uniprotkb:Cyclin-dependent protein kinase H(gene name synonym)|uniprotkb:Cyclin-kinase-activating kinase p42(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2011)	pubmed:21986944|imex:IM-17350	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6128605|imex:IM-17350-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005897.1|refseq:XP_011512921.1|refseq:XP_011512922.1|refseq:XP_011512924.1|refseq:NP_001229314.1|refseq:NP_001229886.1|ensembl:ENSG00000111837(gene)|ensembl:ENST00000313243(transcript)|ensembl:ENST00000474039(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042073"(intraciliary transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_016866352.1|refseq:XP_016866353.1	refseq:NP_001034892.1|refseq:NP_001164110.1|refseq:NP_001164111.1|refseq:NP_036251.2|refseq:NP_848519.1|ensembl:ENSG00000156345(gene)|ensembl:ENST00000325303(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)	-	-	-	figure legend:Figure 3D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/05/17	2014/10/16	rogid:iQZUfQy6U56KxyAhMZrev3DnpNc9606	rogid:THgAKwmi8DxhHaFmRHjG3sHJGmg9606	intact-crc:B2762F01D667DABA|rigid:oVgYTn7m4ugzlLHkzP3eSEmbpWw	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UM11	uniprotkb:P20794	intact:EBI-724997|uniprotkb:O75869|uniprotkb:Q86U66|uniprotkb:Q96NW8|uniprotkb:Q9UI96|uniprotkb:Q9ULH8|uniprotkb:Q9UM10|uniprotkb:Q9UNQ1|uniprotkb:Q9Y2T8|intact:EBI-2558941|ensembl:ENSP00000378529	intact:EBI-3911321|uniprotkb:Q9NUH7|uniprotkb:F1T0K6|uniprotkb:G1FL29|uniprotkb:Q547D0|ensembl:ENSP00000313021|ensembl:ENSP00000476067	psi-mi:fzr1_human(display_long)|uniprotkb:FYR(gene name synonym)|uniprotkb:FZR(gene name synonym)|uniprotkb:KIAA1242(gene name synonym)|uniprotkb:FZR1(gene name)|psi-mi:FZR1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:Cdh1/Hct1 homolog(gene name synonym)|uniprotkb:CDC20-like protein 1(gene name synonym)	psi-mi:mak_human(display_long)|uniprotkb:MAK(gene name)|psi-mi:MAK(display_short)|uniprotkb:Male germ cell-associated kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2011)	pubmed:21986944|imex:IM-17350	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6128614|imex:IM-17350-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129669.1|refseq:NP_001129670.1|refseq:NP_057347.2|ensembl:ENSG00000105325(gene)|ensembl:ENST00000395095(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9UM11|rcsb pdb:4UI9|rcsb pdb:5L9T|rcsb pdb:5L9U|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174178|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176417|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-69656|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:XP_005259630.1|dip:DIP-38700N	refseq:NP_005897.1|refseq:XP_011512921.1|refseq:XP_011512922.1|refseq:XP_011512924.1|refseq:NP_001229314.1|refseq:NP_001229886.1|ensembl:ENSG00000111837(gene)|ensembl:ENST00000313243(transcript)|ensembl:ENST00000474039(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042073"(intraciliary transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_016866352.1|refseq:XP_016866353.1	-	-	-	figure legend:Figure 4A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/05/17	2014/10/16	rogid:ABjKu6y+1XKC9gBB/k0uV4w1sHM9606	rogid:iQZUfQy6U56KxyAhMZrev3DnpNc9606	intact-crc:DB345D44B0B5AE5A|rigid:tJMQkrDEc2SKW2r9ziyUYLMUK+Q	false	ha tag:n-n	v5 tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P20794	uniprotkb:Q9UM11	intact:EBI-3911321|uniprotkb:Q9NUH7|uniprotkb:F1T0K6|uniprotkb:G1FL29|uniprotkb:Q547D0|ensembl:ENSP00000313021|ensembl:ENSP00000476067	intact:EBI-724997|uniprotkb:O75869|uniprotkb:Q86U66|uniprotkb:Q96NW8|uniprotkb:Q9UI96|uniprotkb:Q9ULH8|uniprotkb:Q9UM10|uniprotkb:Q9UNQ1|uniprotkb:Q9Y2T8|intact:EBI-2558941|ensembl:ENSP00000378529	psi-mi:mak_human(display_long)|uniprotkb:MAK(gene name)|psi-mi:MAK(display_short)|uniprotkb:Male germ cell-associated kinase(gene name synonym)	psi-mi:fzr1_human(display_long)|uniprotkb:FYR(gene name synonym)|uniprotkb:FZR(gene name synonym)|uniprotkb:KIAA1242(gene name synonym)|uniprotkb:FZR1(gene name)|psi-mi:FZR1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:Cdh1/Hct1 homolog(gene name synonym)|uniprotkb:CDC20-like protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2011)	pubmed:21986944|imex:IM-17350	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6128714|imex:IM-17350-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005897.1|refseq:XP_011512921.1|refseq:XP_011512922.1|refseq:XP_011512924.1|refseq:NP_001229314.1|refseq:NP_001229886.1|ensembl:ENSG00000111837(gene)|ensembl:ENST00000313243(transcript)|ensembl:ENST00000474039(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042073"(intraciliary transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_016866352.1|refseq:XP_016866353.1	refseq:NP_001129669.1|refseq:NP_001129670.1|refseq:NP_057347.2|ensembl:ENSG00000105325(gene)|ensembl:ENST00000395095(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9UM11|rcsb pdb:4UI9|rcsb pdb:5L9T|rcsb pdb:5L9U|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174178|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176417|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-69656|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:XP_005259630.1|dip:DIP-38700N	-	-	-	figure legend:Figure 4B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-du_145)|taxid:9606(Homo sapiens DU-145 prostate cancer cell line)	-	2012/05/17	2014/10/16	rogid:iQZUfQy6U56KxyAhMZrev3DnpNc9606	rogid:ABjKu6y+1XKC9gBB/k0uV4w1sHM9606	intact-crc:55073383537D9BEB|rigid:tJMQkrDEc2SKW2r9ziyUYLMUK+Q	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UM11	uniprotkb:P20794	intact:EBI-724997|uniprotkb:O75869|uniprotkb:Q86U66|uniprotkb:Q96NW8|uniprotkb:Q9UI96|uniprotkb:Q9ULH8|uniprotkb:Q9UM10|uniprotkb:Q9UNQ1|uniprotkb:Q9Y2T8|intact:EBI-2558941|ensembl:ENSP00000378529	intact:EBI-3911321|uniprotkb:Q9NUH7|uniprotkb:F1T0K6|uniprotkb:G1FL29|uniprotkb:Q547D0|ensembl:ENSP00000313021|ensembl:ENSP00000476067	psi-mi:fzr1_human(display_long)|uniprotkb:FYR(gene name synonym)|uniprotkb:FZR(gene name synonym)|uniprotkb:KIAA1242(gene name synonym)|uniprotkb:FZR1(gene name)|psi-mi:FZR1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:Cdh1/Hct1 homolog(gene name synonym)|uniprotkb:CDC20-like protein 1(gene name synonym)	psi-mi:mak_human(display_long)|uniprotkb:MAK(gene name)|psi-mi:MAK(display_short)|uniprotkb:Male germ cell-associated kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2011)	pubmed:21986944|imex:IM-17350	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6139881|imex:IM-17350-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129669.1|refseq:NP_001129670.1|refseq:NP_057347.2|ensembl:ENSG00000105325(gene)|ensembl:ENST00000395095(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9UM11|rcsb pdb:4UI9|rcsb pdb:5L9T|rcsb pdb:5L9U|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174178|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176417|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-69656|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:XP_005259630.1|dip:DIP-38700N	refseq:NP_005897.1|refseq:XP_011512921.1|refseq:XP_011512922.1|refseq:XP_011512924.1|refseq:NP_001229314.1|refseq:NP_001229886.1|ensembl:ENSG00000111837(gene)|ensembl:ENST00000313243(transcript)|ensembl:ENST00000474039(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042073"(intraciliary transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_016866352.1|refseq:XP_016866353.1	-	-	-	figure legend:Fig 4B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-cwr22rv1)|taxid:9606(Homo sapiens)	-	2012/05/17	2014/10/16	rogid:ABjKu6y+1XKC9gBB/k0uV4w1sHM9606	rogid:iQZUfQy6U56KxyAhMZrev3DnpNc9606	intact-crc:3F960F573AAD1C4C|rigid:tJMQkrDEc2SKW2r9ziyUYLMUK+Q	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P20794	uniprotkb:Q9UM11	intact:EBI-3911321|uniprotkb:Q9NUH7|uniprotkb:F1T0K6|uniprotkb:G1FL29|uniprotkb:Q547D0|ensembl:ENSP00000313021|ensembl:ENSP00000476067	intact:EBI-724997|uniprotkb:O75869|uniprotkb:Q86U66|uniprotkb:Q96NW8|uniprotkb:Q9UI96|uniprotkb:Q9ULH8|uniprotkb:Q9UM10|uniprotkb:Q9UNQ1|uniprotkb:Q9Y2T8|intact:EBI-2558941|ensembl:ENSP00000378529	psi-mi:mak_human(display_long)|uniprotkb:MAK(gene name)|psi-mi:MAK(display_short)|uniprotkb:Male germ cell-associated kinase(gene name synonym)	psi-mi:fzr1_human(display_long)|uniprotkb:FYR(gene name synonym)|uniprotkb:FZR(gene name synonym)|uniprotkb:KIAA1242(gene name synonym)|uniprotkb:FZR1(gene name)|psi-mi:FZR1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:Cdh1/Hct1 homolog(gene name synonym)|uniprotkb:CDC20-like protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2011)	pubmed:21986944|imex:IM-17350	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6139893|imex:IM-17350-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005897.1|refseq:XP_011512921.1|refseq:XP_011512922.1|refseq:XP_011512924.1|refseq:NP_001229314.1|refseq:NP_001229886.1|ensembl:ENSG00000111837(gene)|ensembl:ENST00000313243(transcript)|ensembl:ENST00000474039(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042073"(intraciliary transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_016866352.1|refseq:XP_016866353.1	refseq:NP_001129669.1|refseq:NP_001129670.1|refseq:NP_057347.2|ensembl:ENSG00000105325(gene)|ensembl:ENST00000395095(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9UM11|rcsb pdb:4UI9|rcsb pdb:5L9T|rcsb pdb:5L9U|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174178|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176417|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-69656|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:XP_005259630.1|dip:DIP-38700N	-	-	-	figure legend:Fig 4B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-pc3)|taxid:9606(Human PC3 Caucasian prostate adenocarcinoma)	-	2012/05/17	2014/10/16	rogid:iQZUfQy6U56KxyAhMZrev3DnpNc9606	rogid:ABjKu6y+1XKC9gBB/k0uV4w1sHM9606	intact-crc:41C7DE95ED1E466D|rigid:tJMQkrDEc2SKW2r9ziyUYLMUK+Q	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P20794	uniprotkb:Q9UM11	intact:EBI-3911321|uniprotkb:Q9NUH7|uniprotkb:F1T0K6|uniprotkb:G1FL29|uniprotkb:Q547D0|ensembl:ENSP00000313021|ensembl:ENSP00000476067	intact:EBI-724997|uniprotkb:O75869|uniprotkb:Q86U66|uniprotkb:Q96NW8|uniprotkb:Q9UI96|uniprotkb:Q9ULH8|uniprotkb:Q9UM10|uniprotkb:Q9UNQ1|uniprotkb:Q9Y2T8|intact:EBI-2558941|ensembl:ENSP00000378529	psi-mi:mak_human(display_long)|uniprotkb:MAK(gene name)|psi-mi:MAK(display_short)|uniprotkb:Male germ cell-associated kinase(gene name synonym)	psi-mi:fzr1_human(display_long)|uniprotkb:FYR(gene name synonym)|uniprotkb:FZR(gene name synonym)|uniprotkb:KIAA1242(gene name synonym)|uniprotkb:FZR1(gene name)|psi-mi:FZR1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:Cdh1/Hct1 homolog(gene name synonym)|uniprotkb:CDC20-like protein 1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Wang et al. (2011)	pubmed:21986944|imex:IM-17350	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6140954|imex:IM-17350-6	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005897.1|refseq:XP_011512921.1|refseq:XP_011512922.1|refseq:XP_011512924.1|refseq:NP_001229314.1|refseq:NP_001229886.1|ensembl:ENSG00000111837(gene)|ensembl:ENST00000313243(transcript)|ensembl:ENST00000474039(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042073"(intraciliary transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_016866352.1|refseq:XP_016866353.1	refseq:NP_001129669.1|refseq:NP_001129670.1|refseq:NP_057347.2|ensembl:ENSG00000105325(gene)|ensembl:ENST00000395095(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9UM11|rcsb pdb:4UI9|rcsb pdb:5L9T|rcsb pdb:5L9U|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174178|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176417|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-69656|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:XP_005259630.1|dip:DIP-38700N	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:Figure 5a|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/17	2014/10/16	rogid:iQZUfQy6U56KxyAhMZrev3DnpNc9606	rogid:ABjKu6y+1XKC9gBB/k0uV4w1sHM9606	intact-crc:4182AC3D56B041AB|rigid:tJMQkrDEc2SKW2r9ziyUYLMUK+Q	false	v5 tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:Q9UM11	uniprotkb:P20794	intact:EBI-724997|uniprotkb:O75869|uniprotkb:Q86U66|uniprotkb:Q96NW8|uniprotkb:Q9UI96|uniprotkb:Q9ULH8|uniprotkb:Q9UM10|uniprotkb:Q9UNQ1|uniprotkb:Q9Y2T8|intact:EBI-2558941|ensembl:ENSP00000378529	intact:EBI-3911321|uniprotkb:Q9NUH7|uniprotkb:F1T0K6|uniprotkb:G1FL29|uniprotkb:Q547D0|ensembl:ENSP00000313021|ensembl:ENSP00000476067	psi-mi:fzr1_human(display_long)|uniprotkb:FYR(gene name synonym)|uniprotkb:FZR(gene name synonym)|uniprotkb:KIAA1242(gene name synonym)|uniprotkb:FZR1(gene name)|psi-mi:FZR1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:Cdh1/Hct1 homolog(gene name synonym)|uniprotkb:CDC20-like protein 1(gene name synonym)	psi-mi:mak_human(display_long)|uniprotkb:MAK(gene name)|psi-mi:MAK(display_short)|uniprotkb:Male germ cell-associated kinase(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Wang et al. (2011)	pubmed:21986944|imex:IM-17350	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6141032|imex:IM-17350-7	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129669.1|refseq:NP_001129670.1|refseq:NP_057347.2|ensembl:ENSG00000105325(gene)|ensembl:ENST00000395095(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9UM11|rcsb pdb:4UI9|rcsb pdb:5L9T|rcsb pdb:5L9U|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174178|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176417|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-69656|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:XP_005259630.1|dip:DIP-38700N	refseq:NP_005897.1|refseq:XP_011512921.1|refseq:XP_011512922.1|refseq:XP_011512924.1|refseq:NP_001229314.1|refseq:NP_001229886.1|ensembl:ENSG00000111837(gene)|ensembl:ENST00000313243(transcript)|ensembl:ENST00000474039(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042073"(intraciliary transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_016866352.1|refseq:XP_016866353.1	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	figure legend:Figure 5b|comment:MAK phosphorylates CDH1 during G2 to M phase.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/17	2014/10/16	rogid:ABjKu6y+1XKC9gBB/k0uV4w1sHM9606	rogid:iQZUfQy6U56KxyAhMZrev3DnpNc9606	intact-crc:08D6AB45BA0AFC3B|rigid:tJMQkrDEc2SKW2r9ziyUYLMUK+Q	false	glutathione s tranferase tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P20794	uniprotkb:Q9UM11	intact:EBI-3911321|uniprotkb:Q9NUH7|uniprotkb:F1T0K6|uniprotkb:G1FL29|uniprotkb:Q547D0|ensembl:ENSP00000313021|ensembl:ENSP00000476067	intact:EBI-724997|uniprotkb:O75869|uniprotkb:Q86U66|uniprotkb:Q96NW8|uniprotkb:Q9UI96|uniprotkb:Q9ULH8|uniprotkb:Q9UM10|uniprotkb:Q9UNQ1|uniprotkb:Q9Y2T8|intact:EBI-2558941|ensembl:ENSP00000378529	psi-mi:mak_human(display_long)|uniprotkb:MAK(gene name)|psi-mi:MAK(display_short)|uniprotkb:Male germ cell-associated kinase(gene name synonym)	psi-mi:fzr1_human(display_long)|uniprotkb:FYR(gene name synonym)|uniprotkb:FZR(gene name synonym)|uniprotkb:KIAA1242(gene name synonym)|uniprotkb:FZR1(gene name)|psi-mi:FZR1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:Cdh1/Hct1 homolog(gene name synonym)|uniprotkb:CDC20-like protein 1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Wang et al. (2011)	pubmed:21986944|imex:IM-17350	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6141044|imex:IM-17350-8	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005897.1|refseq:XP_011512921.1|refseq:XP_011512922.1|refseq:XP_011512924.1|refseq:NP_001229314.1|refseq:NP_001229886.1|ensembl:ENSG00000111837(gene)|ensembl:ENST00000313243(transcript)|ensembl:ENST00000474039(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042073"(intraciliary transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_016866352.1|refseq:XP_016866353.1	refseq:NP_001129669.1|refseq:NP_001129670.1|refseq:NP_057347.2|ensembl:ENSG00000105325(gene)|ensembl:ENST00000395095(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|mint:Q9UM11|rcsb pdb:4UI9|rcsb pdb:5L9T|rcsb pdb:5L9U|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174178|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176417|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-69656|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|refseq:XP_005259630.1|dip:DIP-38700N	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:Figure 5c|comment:"Mutant CDH1(4A) lacks the four major phosphoacceptor sites of CDK (S40A, T121A, S151A, S163A) and mutant CDH1(9A) lacks all nine acceptor sites (T32, S36, S40, S70, T121, S138, S146, S151, S163). Phosphorylation of CDH1(4A) by  MAK was significantly diminished, and only marginal phosphorylation of CDH1(9A) could be detected"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/17	2014/10/16	rogid:iQZUfQy6U56KxyAhMZrev3DnpNc9606	rogid:ABjKu6y+1XKC9gBB/k0uV4w1sHM9606	intact-crc:3060FD24DF85F72D|rigid:tJMQkrDEc2SKW2r9ziyUYLMUK+Q	false	glutathione s tranferase tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)