#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q06831	uniprotkb:O00560	intact:EBI-6262177|ensembl:ENSMUSP00000100013|uniprotkb:Q5SW95	intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	psi-mi:sox4_mouse(display_long)|uniprotkb:Sox4(gene name)|psi-mi:Sox4(display_short)|uniprotkb:Sox-4(gene name synonym)	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Beekman et al. (2012)	pubmed:21986941|imex:IM-17665	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-6262229|imex:IM-17665-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000076431(gene)|ensembl:ENSMUST00000067230(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001841"(neural tube formation)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003357"(noradrenergic neuron differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0021510"(spinal cord development)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021782"(glial cell development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0035910"(ascending aorta morphogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0050821"(protein stabilization)|go:"GO:0060174"(limb bud formation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000761"(positive regulation of N-terminal peptidyl-lysine acetylation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017386(SOX-12/11/4a)|interpro:IPR036910|rcsb pdb:3U2B|reactome:R-MMU-3769402|refseq:NP_033264.2	ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N	-	-	-	figure legend:4d|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/02	2014/10/16	rogid:hhgRtnQRA+eqH6TmIRB5S4hl/Oc10090	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	intact-crc:7AE1B5BAA866EEEF|rigid:mZz+w4XDQwmrmIGgFWvfy+eI3k8	false	sufficient binding region:59-135|sufficient binding region:299-440|flag tag:n-n	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00560	uniprotkb:Q06831	intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	intact:EBI-6262177|ensembl:ENSMUSP00000100013|uniprotkb:Q5SW95	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	psi-mi:sox4_mouse(display_long)|uniprotkb:Sox4(gene name)|psi-mi:Sox4(display_short)|uniprotkb:Sox-4(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Beekman et al. (2012)	pubmed:21986941|imex:IM-17665	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1262"(I2D)	intact:EBI-6262260|imex:IM-17665-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N	ensembl:ENSMUSG00000076431(gene)|ensembl:ENSMUST00000067230(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001841"(neural tube formation)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003357"(noradrenergic neuron differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0021510"(spinal cord development)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021782"(glial cell development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0035910"(ascending aorta morphogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0050821"(protein stabilization)|go:"GO:0060174"(limb bud formation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000761"(positive regulation of N-terminal peptidyl-lysine acetylation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017386(SOX-12/11/4a)|interpro:IPR036910|rcsb pdb:3U2B|reactome:R-MMU-3769402|refseq:NP_033264.2	go:"GO:0005634"(nucleus)	-	-	figure legend:5a,b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/02	2014/10/16	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	rogid:hhgRtnQRA+eqH6TmIRB5S4hl/Oc10090	intact-crc:95655EE74260F3F3|rigid:mZz+w4XDQwmrmIGgFWvfy+eI3k8	false	mkate2:?-?	enhanced green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q06831	uniprotkb:O00560	intact:EBI-6262177|ensembl:ENSMUSP00000100013|uniprotkb:Q5SW95	intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	psi-mi:sox4_mouse(display_long)|uniprotkb:Sox4(gene name)|psi-mi:Sox4(display_short)|uniprotkb:Sox-4(gene name synonym)	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Beekman et al. (2012)	pubmed:21986941|imex:IM-17665	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1262"(I2D)	intact:EBI-6262276|imex:IM-17665-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000076431(gene)|ensembl:ENSMUST00000067230(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001841"(neural tube formation)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003357"(noradrenergic neuron differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0021510"(spinal cord development)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021782"(glial cell development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0035910"(ascending aorta morphogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0050821"(protein stabilization)|go:"GO:0060174"(limb bud formation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000761"(positive regulation of N-terminal peptidyl-lysine acetylation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017386(SOX-12/11/4a)|interpro:IPR036910|rcsb pdb:3U2B|reactome:R-MMU-3769402|refseq:NP_033264.2	ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N	go:"GO:0005634"(nucleus)	-	-	figure legend:5d,e|comment:Sox4 mutants that fail to localize to the nucleus fail to induce nuclear relocalization of syntenin suggesting that Sox4 modulates syntenin subcellular localization.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/02	2014/10/16	rogid:hhgRtnQRA+eqH6TmIRB5S4hl/Oc10090	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	intact-crc:73EC13BE1D27DE4F|rigid:mZz+w4XDQwmrmIGgFWvfy+eI3k8	false	flag tag:n-n	ha tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)