#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q64487	uniprotkb:P59823	intact:EBI-771834|uniprotkb:Q64486|uniprotkb:Q64488|uniprotkb:Q64495|intact:EBI-6132324|intact:EBI-5778480|uniprotkb:G3X9S7|uniprotkb:Q8VBV0|ensembl:ENSMUSP00000102910	intact:EBI-5452114	psi-mi:ptprd_mouse(display_long)|uniprotkb:Ptprd(gene name)|psi-mi:Ptprd(display_short)	psi-mi:irpl1_mouse(display_long)|uniprotkb:Il1rapl1(gene name)|psi-mi:Il1rapl1(display_short)|uniprotkb:X-linked interleukin-1 receptor accessory protein-like 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yoshida et al. (2011)	pubmed:21940441|imex:IM-17332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5452112|imex:IM-17332-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035341.2|ensembl:ENSMUSG00000028399(gene)|ensembl:ENSMUST00000107289(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:4Y61|rcsb pdb:4YFD|rcsb pdb:4YFE|rcsb pdb:4YFG|rcsb pdb:4YH7|rcsb pdb:5XWT|rcsb pdb:5XWU|rcsb pdb:5Y32|rcsb pdb:6KIP|rcsb pdb:7CEG|reactome:R-MMU-388844|reactome:R-MMU-8849932	interpro:IPR013151(Immunoglobulin)|rcsb pdb:4YH6|rcsb pdb:4YH7|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR035897|interpro:IPR036179|rcsb pdb:5Y32|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR041416|reactome:R-MMU-388844|reactome:R-MMU-9007892	-	-	-	figure legend:Fig 3|comment:"LC-MS/MS identified the meA peptide in PTPdelta protein purified by the affinity chromatography with IL1RAPL1-ECD (Fig. 3B)."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2012/02/07	2014/10/16	rogid:FkLHZVFqjCRQ5GQ+76uKWFhBYYg10090	rogid:7HqTeWhhcJ01KSt/8XAIoejNn2U10090	intact-crc:57EABA96E60F1033|rigid:XTU+EQOkP9KNDzimGqxaTI7V3ko	false	-	fc-igg tag:?-?|sufficient binding region:25..25-357..357	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q64487	uniprotkb:P59823	intact:EBI-771834|uniprotkb:Q64486|uniprotkb:Q64488|uniprotkb:Q64495|intact:EBI-6132324|intact:EBI-5778480|uniprotkb:G3X9S7|uniprotkb:Q8VBV0|ensembl:ENSMUSP00000102910	intact:EBI-5452114	psi-mi:ptprd_mouse(display_long)|uniprotkb:Ptprd(gene name)|psi-mi:Ptprd(display_short)	psi-mi:irpl1_mouse(display_long)|uniprotkb:Il1rapl1(gene name)|psi-mi:Il1rapl1(display_short)|uniprotkb:X-linked interleukin-1 receptor accessory protein-like 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yoshida et al. (2011)	pubmed:21940441|imex:IM-17332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5452233|imex:IM-17332-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035341.2|ensembl:ENSMUSG00000028399(gene)|ensembl:ENSMUST00000107289(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:4Y61|rcsb pdb:4YFD|rcsb pdb:4YFE|rcsb pdb:4YFG|rcsb pdb:4YH7|rcsb pdb:5XWT|rcsb pdb:5XWU|rcsb pdb:5Y32|rcsb pdb:6KIP|rcsb pdb:7CEG|reactome:R-MMU-388844|reactome:R-MMU-8849932	interpro:IPR013151(Immunoglobulin)|rcsb pdb:4YH6|rcsb pdb:4YH7|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR035897|interpro:IPR036179|rcsb pdb:5Y32|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR041416|reactome:R-MMU-388844|reactome:R-MMU-9007892	-	-	-	figure legend:Fig 3B|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2012/02/07	2014/10/16	rogid:FkLHZVFqjCRQ5GQ+76uKWFhBYYg10090	rogid:7HqTeWhhcJ01KSt/8XAIoejNn2U10090	intact-crc:1217BCBA78540C17|rigid:XTU+EQOkP9KNDzimGqxaTI7V3ko	false	binding-associated region:1357..1357-1903..1903(IPR000242)	fc-igg tag:?-?|sufficient binding region:25..25-357..357	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q64487	uniprotkb:P59823	intact:EBI-771834|uniprotkb:Q64486|uniprotkb:Q64488|uniprotkb:Q64495|intact:EBI-6132324|intact:EBI-5778480|uniprotkb:G3X9S7|uniprotkb:Q8VBV0|ensembl:ENSMUSP00000102910	intact:EBI-5452114	psi-mi:ptprd_mouse(display_long)|uniprotkb:Ptprd(gene name)|psi-mi:Ptprd(display_short)	psi-mi:irpl1_mouse(display_long)|uniprotkb:Il1rapl1(gene name)|psi-mi:Il1rapl1(display_short)|uniprotkb:X-linked interleukin-1 receptor accessory protein-like 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yoshida et al. (2011)	pubmed:21940441|imex:IM-17332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5452437|imex:IM-17332-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035341.2|ensembl:ENSMUSG00000028399(gene)|ensembl:ENSMUST00000107289(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:4Y61|rcsb pdb:4YFD|rcsb pdb:4YFE|rcsb pdb:4YFG|rcsb pdb:4YH7|rcsb pdb:5XWT|rcsb pdb:5XWU|rcsb pdb:5Y32|rcsb pdb:6KIP|rcsb pdb:7CEG|reactome:R-MMU-388844|reactome:R-MMU-8849932	interpro:IPR013151(Immunoglobulin)|rcsb pdb:4YH6|rcsb pdb:4YH7|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR035897|interpro:IPR036179|rcsb pdb:5Y32|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR041416|reactome:R-MMU-388844|reactome:R-MMU-9007892	-	-	-	figure legend:Fig 4B|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuron)|taxid:10090(Mus musculus neuronal cell)	-	2012/02/07	2014/10/16	rogid:FkLHZVFqjCRQ5GQ+76uKWFhBYYg10090	rogid:7HqTeWhhcJ01KSt/8XAIoejNn2U10090	intact-crc:687C4587775F7958|rigid:XTU+EQOkP9KNDzimGqxaTI7V3ko	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P59823	uniprotkb:Q64487	intact:EBI-5452114	intact:EBI-771834|uniprotkb:Q64486|uniprotkb:Q64488|uniprotkb:Q64495|intact:EBI-6132324|intact:EBI-5778480|uniprotkb:G3X9S7|uniprotkb:Q8VBV0|ensembl:ENSMUSP00000102910	psi-mi:irpl1_mouse(display_long)|uniprotkb:Il1rapl1(gene name)|psi-mi:Il1rapl1(display_short)|uniprotkb:X-linked interleukin-1 receptor accessory protein-like 1(gene name synonym)	psi-mi:ptprd_mouse(display_long)|uniprotkb:Ptprd(gene name)|psi-mi:Ptprd(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Yoshida et al. (2011)	pubmed:21940441|imex:IM-17332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5452448|imex:IM-17332-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013151(Immunoglobulin)|rcsb pdb:4YH6|rcsb pdb:4YH7|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR035897|interpro:IPR036179|rcsb pdb:5Y32|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR041416|reactome:R-MMU-388844|reactome:R-MMU-9007892	refseq:NP_035341.2|ensembl:ENSMUSG00000028399(gene)|ensembl:ENSMUST00000107289(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:4Y61|rcsb pdb:4YFD|rcsb pdb:4YFE|rcsb pdb:4YFG|rcsb pdb:4YH7|rcsb pdb:5XWT|rcsb pdb:5XWU|rcsb pdb:5Y32|rcsb pdb:6KIP|rcsb pdb:7CEG|reactome:R-MMU-388844|reactome:R-MMU-8849932	-	-	-	figure legend:Fig 4C|comment:The transfected cells aggregated into large clumps.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/07	2014/10/16	rogid:7HqTeWhhcJ01KSt/8XAIoejNn2U10090	rogid:FkLHZVFqjCRQ5GQ+76uKWFhBYYg10090	intact-crc:104F25AC5AD913C7|rigid:XTU+EQOkP9KNDzimGqxaTI7V3ko	false	enhanced green fluorescent protein tag:?-?	red fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q64487	uniprotkb:P0C192	intact:EBI-771834|uniprotkb:Q64486|uniprotkb:Q64488|uniprotkb:Q64495|intact:EBI-6132324|intact:EBI-5778480|uniprotkb:G3X9S7|uniprotkb:Q8VBV0|ensembl:ENSMUSP00000102910	intact:EBI-5452515|ensembl:ENSMUSP00000053123	psi-mi:ptprd_mouse(display_long)|uniprotkb:Ptprd(gene name)|psi-mi:Ptprd(display_short)	psi-mi:lrc4b_mouse(display_long)|uniprotkb:Lrrc4b(gene name)|psi-mi:Lrrc4b(display_short)|uniprotkb:Lrig4(gene name synonym)|uniprotkb:Netrin-G3 ligand(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Yoshida et al. (2011)	pubmed:21940441|imex:IM-17332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5452512|imex:IM-17332-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035341.2|ensembl:ENSMUSG00000028399(gene)|ensembl:ENSMUST00000107289(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:4Y61|rcsb pdb:4YFD|rcsb pdb:4YFE|rcsb pdb:4YFG|rcsb pdb:4YH7|rcsb pdb:5XWT|rcsb pdb:5XWU|rcsb pdb:5Y32|rcsb pdb:6KIP|rcsb pdb:7CEG|reactome:R-MMU-388844|reactome:R-MMU-8849932	refseq:NP_937893.1|ensembl:ENSMUSG00000047085(gene)|ensembl:ENSMUST00000058667(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026883|interpro:IPR032675|interpro:IPR036179|mint:P0C192|rcsb pdb:3ZYN|rcsb pdb:3ZYO|reactome:R-MMU-388844|interpro:IPR003599(Immunoglobulin subtype)	go:"GO:0009986"(cell surface)	-	-	figure legend:Fig 4E|comment:The intensity of staining signals for IL1RAPL1-ECD-Fc was much stronger than that for NGL-3-ECD-Fc.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/07	2014/10/16	rogid:FkLHZVFqjCRQ5GQ+76uKWFhBYYg10090	rogid:nn4yJoNW/2Ybm663BJIieMSXuHk10090	intact-crc:F65FB660D1BD3793|rigid:AAxvC63aWCn0iPoYY3/0GVCiaC8	false	-	fc-igg tag:?-?|sufficient binding region:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q64487-4	uniprotkb:P59823	intact:EBI-6138461|ensembl:ENSMUSP00000102910	intact:EBI-5452114	psi-mi:q64487-4(display_long)|uniprotkb:delta(isoform synonym)|uniprotkb:Ptprd(gene name)|psi-mi:Ptprd(display_short)	psi-mi:irpl1_mouse(display_long)|uniprotkb:Il1rapl1(gene name)|psi-mi:Il1rapl1(display_short)|uniprotkb:X-linked interleukin-1 receptor accessory protein-like 1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Yoshida et al. (2011)	pubmed:21940441|imex:IM-17332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5452318|imex:IM-17332-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-771834(isoform-parent)|ensembl:ENSMUSG00000028399(gene)|ensembl:ENSMUST00000107289(transcript)	interpro:IPR013151(Immunoglobulin)|rcsb pdb:4YH6|rcsb pdb:4YH7|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR035897|interpro:IPR036179|rcsb pdb:5Y32|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR041416|reactome:R-MMU-388844|reactome:R-MMU-9007892	go:"GO:0009986"(cell surface)	-	-	figure legend:Fig 4A/4E, 5B/C.|comment:The meA and meB peptides of PTPdelta are critical for the interaction with IL1RAPL1.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/07	2014/10/16	rogid:FkLHZVFqjCRQ5GQ+76uKWFhBYYg10090	rogid:7HqTeWhhcJ01KSt/8XAIoejNn2U10090	intact-crc:15E17C29818A80E3|rigid:XTU+EQOkP9KNDzimGqxaTI7V3ko	false	sufficient binding region:227-230,184-189|sufficient binding region:181-189	fc-igg tag:?-?|sufficient binding region:25..25-357..357	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P59823	uniprotkb:Q64487-4	intact:EBI-5452114	intact:EBI-6138461|ensembl:ENSMUSP00000102910	psi-mi:irpl1_mouse(display_long)|uniprotkb:Il1rapl1(gene name)|psi-mi:Il1rapl1(display_short)|uniprotkb:X-linked interleukin-1 receptor accessory protein-like 1(gene name synonym)	psi-mi:q64487-4(display_long)|uniprotkb:delta(isoform synonym)|uniprotkb:Ptprd(gene name)|psi-mi:Ptprd(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Yoshida et al. (2011)	pubmed:21940441|imex:IM-17332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6138507|imex:IM-17332-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013151(Immunoglobulin)|rcsb pdb:4YH6|rcsb pdb:4YH7|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR035897|interpro:IPR036179|rcsb pdb:5Y32|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR041416|reactome:R-MMU-388844|reactome:R-MMU-9007892	intact:EBI-771834(isoform-parent)|ensembl:ENSMUSG00000028399(gene)|ensembl:ENSMUST00000107289(transcript)	go:"GO:0009986"(cell surface)	-	-	figure legend:Fig 4A/4E, 5B/C -2|comment:The meA and meB peptides of PTPdelta are critical for the interaction with IL1RAPL1.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/07	2014/10/16	rogid:7HqTeWhhcJ01KSt/8XAIoejNn2U10090	rogid:FkLHZVFqjCRQ5GQ+76uKWFhBYYg10090	intact-crc:45EFF49C528F6D2F|rigid:XTU+EQOkP9KNDzimGqxaTI7V3ko	false	sufficient binding region:25..25-357..357|fc-igg tag:?-?	sufficient binding region:181-189|sufficient binding region:227-230,184-189	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P59823	uniprotkb:Q64487	intact:EBI-5452114	intact:EBI-771834|uniprotkb:Q64486|uniprotkb:Q64488|uniprotkb:Q64495|intact:EBI-6132324|intact:EBI-5778480|uniprotkb:G3X9S7|uniprotkb:Q8VBV0|ensembl:ENSMUSP00000102910	psi-mi:irpl1_mouse(display_long)|uniprotkb:Il1rapl1(gene name)|psi-mi:Il1rapl1(display_short)|uniprotkb:X-linked interleukin-1 receptor accessory protein-like 1(gene name synonym)	psi-mi:ptprd_mouse(display_long)|uniprotkb:Ptprd(gene name)|psi-mi:Ptprd(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Yoshida et al. (2011)	pubmed:21940441|imex:IM-17332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5452486|imex:IM-17332-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013151(Immunoglobulin)|rcsb pdb:4YH6|rcsb pdb:4YH7|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR035897|interpro:IPR036179|rcsb pdb:5Y32|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR041416|reactome:R-MMU-388844|reactome:R-MMU-9007892	refseq:NP_035341.2|ensembl:ENSMUSG00000028399(gene)|ensembl:ENSMUST00000107289(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:4Y61|rcsb pdb:4YFD|rcsb pdb:4YFE|rcsb pdb:4YFG|rcsb pdb:4YH7|rcsb pdb:5XWT|rcsb pdb:5XWU|rcsb pdb:5Y32|rcsb pdb:6KIP|rcsb pdb:7CEG|reactome:R-MMU-388844|reactome:R-MMU-8849932	-	-	-	figure legend:Fig 4D|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.0x10^-7(molar)	2012/02/07	2014/10/16	rogid:7HqTeWhhcJ01KSt/8XAIoejNn2U10090	rogid:FkLHZVFqjCRQ5GQ+76uKWFhBYYg10090	intact-crc:6B530F5BEFBE60F7|rigid:XTU+EQOkP9KNDzimGqxaTI7V3ko	false	fc-igg tag:?-?|sufficient binding region:25..25-357..357	binding-associated region:21..21-1266..1266|myc tag:?-?|his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q64487	uniprotkb:P59823	intact:EBI-771834|uniprotkb:Q64486|uniprotkb:Q64488|uniprotkb:Q64495|intact:EBI-6132324|intact:EBI-5778480|uniprotkb:G3X9S7|uniprotkb:Q8VBV0|ensembl:ENSMUSP00000102910	intact:EBI-5452114	psi-mi:ptprd_mouse(display_long)|uniprotkb:Ptprd(gene name)|psi-mi:Ptprd(display_short)	psi-mi:irpl1_mouse(display_long)|uniprotkb:Il1rapl1(gene name)|psi-mi:Il1rapl1(display_short)|uniprotkb:X-linked interleukin-1 receptor accessory protein-like 1(gene name synonym)	psi-mi:"MI:0405"(competition binding)	Yoshida et al. (2011)	pubmed:21940441|imex:IM-17332	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5452576|imex:IM-17332-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035341.2|ensembl:ENSMUSG00000028399(gene)|ensembl:ENSMUST00000107289(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:4Y61|rcsb pdb:4YFD|rcsb pdb:4YFE|rcsb pdb:4YFG|rcsb pdb:4YH7|rcsb pdb:5XWT|rcsb pdb:5XWU|rcsb pdb:5Y32|rcsb pdb:6KIP|rcsb pdb:7CEG|reactome:R-MMU-388844|reactome:R-MMU-8849932	interpro:IPR013151(Immunoglobulin)|rcsb pdb:4YH6|rcsb pdb:4YH7|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR015621(Interleukin-1 receptor)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR035897|interpro:IPR036179|rcsb pdb:5Y32|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR041416|reactome:R-MMU-388844|reactome:R-MMU-9007892	go:"GO:0009986"(cell surface)	-	-	figure legend:Fig 4G|comment:NGL-3-ECD-Fc hardly affected the interaction between PTPdelta and IL1RAPL1-ECD tagged with His epitope.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/02/07	2014/10/16	rogid:FkLHZVFqjCRQ5GQ+76uKWFhBYYg10090	rogid:7HqTeWhhcJ01KSt/8XAIoejNn2U10090	intact-crc:134D68D2802FBD46|rigid:XTU+EQOkP9KNDzimGqxaTI7V3ko	false	-	sufficient binding region:25..25-357..357|his tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)