#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y224 uniprotkb:Q1K9H5 intact:EBI-1104547|ensembl:ENSP00000261700 intact:EBI-6050669|uniprotkb:B4URF5|uniprotkb:A0A1L1U0X5|uniprotkb:Q1I2B1 psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name) psi-mi:q1k9h5_i33a0(display_long)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rodriguez et al. (2011) pubmed:21900157|imex:IM-16898 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6050645|imex:IM-16898-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531 interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus) - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/03/28 2014/10/16 rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606 rogid:YzyMeO13ocp/2fSNHQp/vIolaDs381518 intact-crc:DC51690A86649789|rigid:CKYyROBXl7jS3oyo+zTc1QE+UBo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y224 uniprotkb:B4URF7 intact:EBI-1104547|ensembl:ENSP00000261700 intact:EBI-6050648 psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name) psi-mi:b4urf7_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rodriguez et al. (2011) pubmed:21900157|imex:IM-16898 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6050645|imex:IM-16898-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531 interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/03/28 2014/10/16 rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606 rogid:nEQmjlWfAvsNqkhjRxC9PzCV5tU381518 intact-crc:DC51690A86649789|rigid:CKYyROBXl7jS3oyo+zTc1QE+UBo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y224 uniprotkb:Q1I2B2 intact:EBI-1104547|ensembl:ENSP00000261700 intact:EBI-6050661|uniprotkb:B4URF4 psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name) psi-mi:q1i2b2_i33a0(display_long)|uniprotkb:PA(gene name)|psi-mi:PA(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rodriguez et al. (2011) pubmed:21900157|imex:IM-16898 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6050645|imex:IM-16898-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531 interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR038372|interpro:IPR037534|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching) - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/03/28 2014/10/16 rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606 rogid:Ql7usL6x8LoOsNX1cAXxXi5yWoE381518 intact-crc:DC51690A86649789|rigid:CKYyROBXl7jS3oyo+zTc1QE+UBo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:B4URF7 uniprotkb:Q1K9H2 intact:EBI-6050648 intact:EBI-6050688|uniprotkb:Q1I2B5|uniprotkb:B4URF1 psi-mi:b4urf7_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q1k9h2_i33a0(display_long)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:NP(gene name)|psi-mi:NP(display_short) psi-mi:"MI:0663"(confocal microscopy) Rodriguez et al. (2011) pubmed:21900157|imex:IM-16898 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6050698|imex:IM-16898-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) dip:DIP-60419N|dip:DIP-61893N|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002141("Influenza virus nucleoprotein (NP)")|rcsb pdb:2IQH|rcsb pdb:2YMN|rcsb pdb:3RO5|rcsb pdb:3TG6|rcsb pdb:4BBL|rcsb pdb:4DYA|rcsb pdb:4DYB|rcsb pdb:4DYN|rcsb pdb:4DYP|rcsb pdb:4DYT|rcsb pdb:4IRY|rcsb pdb:5TJW - - - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2012/03/28 2014/10/16 rogid:nEQmjlWfAvsNqkhjRxC9PzCV5tU381518 rogid:2AXeVyyAOsTR6Ait9sowVeAZmno381518 intact-crc:D672B10F32ABF21F|rigid:cahigVqyTzPlG4ApnqJUQ/p33Sc false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:B4URF7 uniprotkb:Q9Y224 intact:EBI-6050648 intact:EBI-1104547|ensembl:ENSP00000261700 psi-mi:b4urf7_i33a0(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name) psi-mi:"MI:0663"(confocal microscopy) Rodriguez et al. (2011) pubmed:21900157|imex:IM-16898 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6050698|imex:IM-16898-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching) refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531 - - - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2012/03/28 2014/10/16 rogid:nEQmjlWfAvsNqkhjRxC9PzCV5tU381518 rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606 intact-crc:D672B10F32ABF21F|rigid:cahigVqyTzPlG4ApnqJUQ/p33Sc false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P31345 uniprotkb:Q9WLG4 intact:EBI-6051231 intact:EBI-6051222 psi-mi:pb2_i75a3(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:q9wlg4_i75a3(display_long)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:NP(gene name)|psi-mi:NP(display_short) psi-mi:"MI:0096"(pull down) Rodriguez et al. (2011) pubmed:21900157|imex:IM-16898 taxid:392809(i75a3)|taxid:392809("Influenza A virus (strain A/Victoria/3/1975 H3N2)") taxid:392809(i75a3)|taxid:392809("Influenza A virus (strain A/Victoria/3/1975 H3N2)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6051263|imex:IM-16898-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-29297N|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|rcsb pdb:2GMO|rcsb pdb:2JDQ|rcsb pdb:2VQZ|rcsb pdb:2VY6|rcsb pdb:2VY7|rcsb pdb:2VY8|rcsb pdb:4NCE|rcsb pdb:4NCM|rcsb pdb:4P1U|rcsb pdb:4UAD|rcsb pdb:4UAE|rcsb pdb:4UAF|rcsb pdb:6EUV|rcsb pdb:6EUY dip:DIP-61894N|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002141("Influenza virus nucleoprotein (NP)") - - - figure legend:2E|comment:"Interaction (viral RNP complex formation) is independent of human C14orf166/CLE."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/03/28 2014/10/16 rogid:vMHH6CyK4jxOxbv+xu+IqHVYi5A392809 rogid:0HyZ3jHC1sHQkG1rvG4pPDdSPjo392809 intact-crc:C1444CC528AD02EC|rigid:QUM52Olp9wI8QzqTVumOqen84pM false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31345 uniprotkb:P31341 intact:EBI-6051231 intact:EBI-6051250 psi-mi:pb2_i75a3(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:rdrp_i75a3(display_long)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym) psi-mi:"MI:0096"(pull down) Rodriguez et al. (2011) pubmed:21900157|imex:IM-16898 taxid:392809(i75a3)|taxid:392809("Influenza A virus (strain A/Victoria/3/1975 H3N2)") taxid:392809(i75a3)|taxid:392809("Influenza A virus (strain A/Victoria/3/1975 H3N2)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6051263|imex:IM-16898-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-29297N|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|rcsb pdb:2GMO|rcsb pdb:2JDQ|rcsb pdb:2VQZ|rcsb pdb:2VY6|rcsb pdb:2VY7|rcsb pdb:2VY8|rcsb pdb:4NCE|rcsb pdb:4NCM|rcsb pdb:4P1U|rcsb pdb:4UAD|rcsb pdb:4UAE|rcsb pdb:4UAF|rcsb pdb:6EUV|rcsb pdb:6EUY dip:DIP-61896N|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype)|interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus) - - - figure legend:2E|comment:"Interaction (viral RNP complex formation) is independent of human C14orf166/CLE."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/03/28 2014/10/16 rogid:vMHH6CyK4jxOxbv+xu+IqHVYi5A392809 rogid:caFh+WWPGrqmXMyDXza+3kOKL38392809 intact-crc:C1444CC528AD02EC|rigid:QUM52Olp9wI8QzqTVumOqen84pM false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31345 uniprotkb:P31343 intact:EBI-6051231 intact:EBI-5800362 psi-mi:pb2_i75a3(display_long)|uniprotkb:PB2(gene name)|psi-mi:PB2(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P3(gene name synonym) psi-mi:pa_i75a3(display_long)|uniprotkb:PA(gene name)|psi-mi:PA(display_short)|uniprotkb:RNA-directed RNA polymerase subunit P2(gene name synonym) psi-mi:"MI:0096"(pull down) Rodriguez et al. (2011) pubmed:21900157|imex:IM-16898 taxid:392809(i75a3)|taxid:392809("Influenza A virus (strain A/Victoria/3/1975 H3N2)") taxid:392809(i75a3)|taxid:392809("Influenza A virus (strain A/Victoria/3/1975 H3N2)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6051263|imex:IM-16898-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-29297N|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0075526"(cap snatching)|interpro:IPR001591(RNA polymerase, PB2 subunit, orthomyxoviridae)|interpro:IPR037258|rcsb pdb:2GMO|rcsb pdb:2JDQ|rcsb pdb:2VQZ|rcsb pdb:2VY6|rcsb pdb:2VY7|rcsb pdb:2VY8|rcsb pdb:4NCE|rcsb pdb:4NCM|rcsb pdb:4P1U|rcsb pdb:4UAD|rcsb pdb:4UAE|rcsb pdb:4UAF|rcsb pdb:6EUV|rcsb pdb:6EUY dip:DIP-61895N|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0075526"(cap snatching)|interpro:IPR001009(RNA-directed RNA polymerase, P2 subunit)|interpro:IPR037534|interpro:IPR038372|rcsb pdb:2W69 - - - figure legend:2E|comment:"Interaction (viral RNP complex formation) is independent of human C14orf166/CLE."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/03/28 2014/10/16 rogid:vMHH6CyK4jxOxbv+xu+IqHVYi5A392809 rogid:3CcbfEkyGMtAhm7PnZpOMXCIl8w392809 intact-crc:C1444CC528AD02EC|rigid:QUM52Olp9wI8QzqTVumOqen84pM false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)