#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P10209 uniprotkb:Q96FN5 intact:EBI-6399718 intact:EBI-3956880|uniprotkb:Q5TBE0|ensembl:ENSP00000473459 psi-mi:cvc2_hhv11(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:UL25(locus name) psi-mi:kif12_human(display_long)|uniprotkb:KIF12(gene name)|psi-mi:KIF12(display_short) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2011) pubmed:21667337 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6509341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002493(Herpesvirus UL25 protein)|rcsb pdb:2F5U|refseq:YP_009137099.1|dip:DIP-60387N refseq:NP_612433.1|ensembl:ENSG00000136883(gene)|ensembl:ENST00000468460(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR028763|interpro:IPR036961|reactome:R-HSA-6811434|reactome:R-HSA-983189 - - - figure legend:Table 2|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/11/30 2014/10/16 rogid:H94XYvXA5NEMxoX5DJ7zd+Y83wA10299 rogid:V8Yvy9MHGLcjXmmLm1Qcf5LHUYk9606 intact-crc:4B1FC4F2EBFAFE27|rigid:DRAB9eEZPCvvGAiGgSc7DPcJhsQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10209 uniprotkb:Q14203 intact:EBI-6399718 intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300 psi-mi:cvc2_hhv11(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:UL25(locus name) psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2011) pubmed:21667337 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6509331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002493(Herpesvirus UL25 protein)|rcsb pdb:2F5U|refseq:YP_009137099.1|dip:DIP-60387N refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N - - - figure legend:Table 2|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/11/30 2014/10/16 rogid:H94XYvXA5NEMxoX5DJ7zd+Y83wA10299 rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606 intact-crc:DE9AA6CBFC822E55|rigid:Jp5OM0aVE6wQO6foKbeGkJZTkXE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10209 uniprotkb:P62826 intact:EBI-6399718 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:cvc2_hhv11(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:UL25(locus name) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2011) pubmed:21667337 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6509326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002493(Herpesvirus UL25 protein)|rcsb pdb:2F5U|refseq:YP_009137099.1|dip:DIP-60387N refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:Table 2|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/11/30 2014/10/16 rogid:H94XYvXA5NEMxoX5DJ7zd+Y83wA10299 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 intact-crc:E2A5D5BE6EBE89C1|rigid:LFME12pgNBlMkL0spIXCaYUH6JQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10209 uniprotkb:H0YL14 intact:EBI-6399718 intact:EBI-6399705|ensembl:ENSP00000452750|ensembl:ENSP00000453019|ensembl:ENSP00000457272 psi-mi:cvc2_hhv11(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:UL25(locus name) psi-mi:tm250_human(display_long)|uniprotkb:TMEM250(gene name)|psi-mi:TMEM250(display_short)|uniprotkb:C9orf69(gene name synonym)|uniprotkb:Herpes virus UL25-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2011) pubmed:21667337 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6399716 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002493(Herpesvirus UL25 protein)|rcsb pdb:2F5U|refseq:YP_009137099.1|dip:DIP-60387N ensembl:ENSG00000238227(gene)|ensembl:ENST00000418388(transcript)|ensembl:ENST00000557985(transcript)|ensembl:ENST00000561457(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005940"(septin ring)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR041156|go:"GO:0034613"(cellular protein localization)|refseq:NP_001243455.1|refseq:NP_690046.3 - - - figure legend:Table 2|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/11/30 2014/10/16 rogid:H94XYvXA5NEMxoX5DJ7zd+Y83wA10299 rogid:LDMM/ezkx1VKB0HvzHiyAwmno2w9606 intact-crc:5EFC5625EF02F801|rigid:XnKH7fb+kcsrPaiL0zibBqRVrrY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01484 uniprotkb:P10209 intact:EBI-941975|uniprotkb:Q01485|uniprotkb:Q08AC7|uniprotkb:Q08AC8|uniprotkb:Q7Z3L5|ensembl:ENSP00000349588 intact:EBI-6399718 psi-mi:ank2_human(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym) psi-mi:cvc2_hhv11(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:UL25(locus name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2011) pubmed:21667337 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6509345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120965.1|refseq:NP_001139.3|refseq:NP_066187.2|dip:DIP-37425N|ensembl:ENSG00000145362(gene)|ensembl:ENST00000357077(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003283"(atrial septum development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745|mint:Q01484|rcsb pdb:4D8O|rcsb pdb:4RLV|rcsb pdb:4RLY|rcsb pdb:5Y4D|rcsb pdb:5Y4E|rcsb pdb:5Y4F|rcsb pdb:5YIR|rcsb pdb:5YIS|rcsb pdb:6KZJ|rcsb pdb:6M3Q|reactome:R-HSA-445095|reactome:R-HSA-6807878 go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002493(Herpesvirus UL25 protein)|rcsb pdb:2F5U|refseq:YP_009137099.1|dip:DIP-60387N - - - figure legend:Table 2|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/11/30 2014/10/16 rogid:wHoFDw3CIP2xOUZj9WzEMGm/z8k9606 rogid:H94XYvXA5NEMxoX5DJ7zd+Y83wA10299 intact-crc:D95FEA7992369B4B|rigid:JmjOCTrApkD+m9Y5fjm6B740dh4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y287 uniprotkb:P10209 intact:EBI-2866431|uniprotkb:Q5W0A3|uniprotkb:Q96B24|uniprotkb:Q9NYH1|ensembl:ENSP00000497221 intact:EBI-6399718 psi-mi:itm2b_human(display_long)|uniprotkb:ITM2B(gene name)|psi-mi:ITM2B(display_short)|uniprotkb:BRI(gene name synonym)|uniprotkb:BRI2(gene name synonym)|uniprotkb:Protein E25B(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)|uniprotkb:Immature BRI2(gene name synonym) psi-mi:cvc2_hhv11(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:UL25(locus name) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2011) pubmed:21667337 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6509335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068839.1|ensembl:ENSG00000136156(gene)|ensembl:ENST00000647800(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|reactome:R-HSA-977225 go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002493(Herpesvirus UL25 protein)|rcsb pdb:2F5U|refseq:YP_009137099.1|dip:DIP-60387N - - - figure legend:Table 2|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/11/30 2014/10/16 rogid:9mHhC4Z61CsmOsTh/1K9oj2NezA9606 rogid:H94XYvXA5NEMxoX5DJ7zd+Y83wA10299 intact-crc:398004D7BDAC31E1|rigid:yp9s3vMZLDNJjaDKJNU/jWpgDF4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10209 uniprotkb:H0YL14 intact:EBI-6399718 intact:EBI-6399705|ensembl:ENSP00000452750|ensembl:ENSP00000453019|ensembl:ENSP00000457272 psi-mi:cvc2_hhv11(display_long)|uniprotkb:CVC2(gene name)|psi-mi:CVC2(display_short)|uniprotkb:UL25(locus name) psi-mi:tm250_human(display_long)|uniprotkb:TMEM250(gene name)|psi-mi:TMEM250(display_short)|uniprotkb:C9orf69(gene name synonym)|uniprotkb:Herpes virus UL25-binding protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zhang et al. (2011) pubmed:21667337 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6399742 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002493(Herpesvirus UL25 protein)|rcsb pdb:2F5U|refseq:YP_009137099.1|dip:DIP-60387N ensembl:ENSG00000238227(gene)|ensembl:ENST00000418388(transcript)|ensembl:ENST00000557985(transcript)|ensembl:ENST00000561457(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005940"(septin ring)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR041156|go:"GO:0034613"(cellular protein localization)|refseq:NP_001243455.1|refseq:NP_690046.3 - - - figure legend:2A|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/11/30 2014/10/16 rogid:H94XYvXA5NEMxoX5DJ7zd+Y83wA10299 rogid:LDMM/ezkx1VKB0HvzHiyAwmno2w9606 intact-crc:B94F4635114F68BA|rigid:XnKH7fb+kcsrPaiL0zibBqRVrrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:H0YL14 uniprotkb:D3YP88 intact:EBI-6399705|ensembl:ENSP00000452750|ensembl:ENSP00000453019|ensembl:ENSP00000457272 intact:EBI-6449813 psi-mi:tm250_human(display_long)|uniprotkb:TMEM250(gene name)|psi-mi:TMEM250(display_short)|uniprotkb:C9orf69(gene name synonym)|uniprotkb:Herpes virus UL25-binding protein(gene name synonym) psi-mi:d3yp88_hhv1(display_long)|uniprotkb:UL25(gene name)|psi-mi:UL25(display_short)|uniprotkb:CVC2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2011) pubmed:21667337 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6399753 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000238227(gene)|ensembl:ENST00000418388(transcript)|ensembl:ENST00000557985(transcript)|ensembl:ENST00000561457(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005940"(septin ring)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR041156|go:"GO:0034613"(cellular protein localization)|refseq:NP_001243455.1|refseq:NP_690046.3 go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002493(Herpesvirus UL25 protein) - - - figure legend:2B lower half|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/30 2014/10/16 rogid:LDMM/ezkx1VKB0HvzHiyAwmno2w9606 rogid:629WHopjP6amiS/FuZkoh8DnZ8E10298 intact-crc:40313B3937E70955|rigid:moujOfySBFfDo5vTHEzezJwMPFo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:H0YL14 uniprotkb:D3YP88 intact:EBI-6399705|ensembl:ENSP00000452750|ensembl:ENSP00000453019|ensembl:ENSP00000457272 intact:EBI-6449813 psi-mi:tm250_human(display_long)|uniprotkb:TMEM250(gene name)|psi-mi:TMEM250(display_short)|uniprotkb:C9orf69(gene name synonym)|uniprotkb:Herpes virus UL25-binding protein(gene name synonym) psi-mi:d3yp88_hhv1(display_long)|uniprotkb:UL25(gene name)|psi-mi:UL25(display_short)|uniprotkb:CVC2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2011) pubmed:21667337 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6399969 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000238227(gene)|ensembl:ENST00000418388(transcript)|ensembl:ENST00000557985(transcript)|ensembl:ENST00000561457(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005940"(septin ring)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR041156|go:"GO:0034613"(cellular protein localization)|refseq:NP_001243455.1|refseq:NP_690046.3 go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002493(Herpesvirus UL25 protein) - - - figure legend:2B upper half|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/30 2014/10/16 rogid:LDMM/ezkx1VKB0HvzHiyAwmno2w9606 rogid:629WHopjP6amiS/FuZkoh8DnZ8E10298 intact-crc:3B6E82CB0931AAD8|rigid:moujOfySBFfDo5vTHEzezJwMPFo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:D3YP88 uniprotkb:H0YL14 intact:EBI-6449813 intact:EBI-6399705|ensembl:ENSP00000452750|ensembl:ENSP00000453019|ensembl:ENSP00000457272 psi-mi:d3yp88_hhv1(display_long)|uniprotkb:UL25(gene name)|psi-mi:UL25(display_short)|uniprotkb:CVC2(gene name synonym) psi-mi:tm250_human(display_long)|uniprotkb:TMEM250(gene name)|psi-mi:TMEM250(display_short)|uniprotkb:C9orf69(gene name synonym)|uniprotkb:Herpes virus UL25-binding protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Zhang et al. (2011) pubmed:21667337 taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6400657 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002493(Herpesvirus UL25 protein) ensembl:ENSG00000238227(gene)|ensembl:ENST00000418388(transcript)|ensembl:ENST00000557985(transcript)|ensembl:ENST00000561457(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005940"(septin ring)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR041156|go:"GO:0034613"(cellular protein localization)|refseq:NP_001243455.1|refseq:NP_690046.3 - - - figure legend:2C|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2012/11/30 2014/10/16 rogid:629WHopjP6amiS/FuZkoh8DnZ8E10298 rogid:LDMM/ezkx1VKB0HvzHiyAwmno2w9606 intact-crc:F2D9B68885DAFE59|rigid:moujOfySBFfDo5vTHEzezJwMPFo false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)