#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0AE67 uniprotkb:P07363 intact:EBI-546693|uniprotkb:P06143|ensemblbacteria:AAC74952|ensemblbacteria:BAA15698 intact:EBI-1026773|uniprotkb:P76302|ensemblbacteria:AAC74958|ensemblbacteria:BAA15709 psi-mi:chey_ecoli(display_long)|uniprotkb:cheY(gene name)|psi-mi:cheY(display_short)|uniprotkb:b1882(locus name)|uniprotkb:JW1871(locus name) psi-mi:chea_ecoli(display_long)|uniprotkb:cheA(gene name)|psi-mi:cheA(display_short)|uniprotkb:b1888(locus name)|uniprotkb:JW1877(locus name) psi-mi:"MI:0051"(fluorescence technology) Thakor et al. (2011) pubmed:21642453|imex:IM-18408 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0903"(mpidb) intact:EBI-6414927|mpidb:MPIDB-INT-1631|imex:IM-18408-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_416396.1|rcsb pdb:3RVQ|rcsb pdb:3RVR|rcsb pdb:3RVP|rcsb pdb:3RVS|rcsb pdb:5CHY|rcsb pdb:5D2C|rcsb pdb:5DGC|rcsb pdb:5DKF|rcsb pdb:6CHY|rcsb pdb:6TG7|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0043052"(thermotaxis)|go:"GO:0097588"(archaeal or bacterial-type flagellum-dependent cell motility)|go:"GO:1902021"(regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|rcsb pdb:1A0O|rcsb pdb:1AB5|rcsb pdb:1AB6|rcsb pdb:1BDJ|rcsb pdb:1C4W|rcsb pdb:1CEY|rcsb pdb:1CHN|rcsb pdb:1CYE|rcsb pdb:1D4Z|rcsb pdb:1DJM|rcsb pdb:1E6K|ensemblbacteria:AAC74952(transcript)|ensemblbacteria:b1882(gene)|ensemblbacteria:BAA15698(gene)|ensemblbacteria:BAA15698(transcript)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006473"(protein acetylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0009454"(aerotaxis)|rcsb pdb:1E6M|rcsb pdb:1EAY|rcsb pdb:1EHC|rcsb pdb:1F4V|rcsb pdb:1FFG|rcsb pdb:1FFS|rcsb pdb:1FFW|rcsb pdb:1FQW|rcsb pdb:1HEY|rcsb pdb:1JBE|rcsb pdb:1KMI|rcsb pdb:1MIH|rcsb pdb:1U8T|rcsb pdb:1UDR|rcsb pdb:1VLZ|rcsb pdb:1YMU|rcsb pdb:1YMV|rcsb pdb:1ZDM|rcsb pdb:1E6L|rcsb pdb:2B1J|rcsb pdb:2ID9|rcsb pdb:2IDM|rcsb pdb:2LP4|rcsb pdb:3CHY|rcsb pdb:3F7N|rcsb pdb:3FFT|rcsb pdb:3FFW|rcsb pdb:3FFX|rcsb pdb:3FGZ|rcsb pdb:3MYY|rcsb pdb:3OLV|rcsb pdb:3OLW|rcsb pdb:2ID7|rcsb pdb:3OLX|rcsb pdb:3OLY|rcsb pdb:3OO0|rcsb pdb:3OO1|rcsb pdb:3RVJ|rcsb pdb:3RVK|rcsb pdb:3RVL|rcsb pdb:3RVM|rcsb pdb:3RVN|rcsb pdb:3RVO|refseq:WP_000763867.1|dip:DIP-6052N refseq:NP_416402.1|refseq:WP_001350517.1|go:"GO:0018106"(peptidyl-histidine phosphorylation)|ensemblbacteria:AAC74958(transcript)|ensemblbacteria:b1888(gene)|ensemblbacteria:BAA15709(gene)|ensemblbacteria:BAA15709(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009454"(aerotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0031400"(negative regulation of protein modification process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051649"(establishment of localization in cell)|go:"GO:0098561"(methyl accepting chemotaxis protein complex)|go:"GO:1901875"(positive regulation of post-translational protein modification)|go:"GO:1902021"(regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR002545(CheW-like protein)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR004105(Signal transduction histidine kinase, subgroup, homodimeric)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR015162(CheY binding)|interpro:IPR035891|interpro:IPR036061|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037006|rcsb pdb:1A0O|rcsb pdb:1EAY|rcsb pdb:1FFG|rcsb pdb:1FFS|rcsb pdb:1FFW|rcsb pdb:1FWP|rcsb pdb:2LP4|rcsb pdb:6S1K|go:"GO:0043052"(thermotaxis)|dip:DIP-6053N - - - figure legend:figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/30 2014/10/16 rogid:EoFDVZXPdOaGEg95ZcoWDMJ/s5483333 rogid:MaWjRuIBsLU60/MZQvfGN+pRyAU83333 intact-crc:7128BDE213D2DC97|rigid:4+nGmCGoEiiqIpAgvp5HQMIBkz4 false fluorescent protein tag:?-? mutation decreasing interaction strength:178-178|sufficient binding region:159-227|mutation disrupting interaction strength:214-214|mutation decreasing interaction strength:216-216|his tag:n-n|mutation decreasing interaction strength:171-171|flag tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P0AE67 uniprotkb:P07363 intact:EBI-546693|uniprotkb:P06143|ensemblbacteria:AAC74952|ensemblbacteria:BAA15698 intact:EBI-1026773|uniprotkb:P76302|ensemblbacteria:AAC74958|ensemblbacteria:BAA15709 psi-mi:chey_ecoli(display_long)|uniprotkb:cheY(gene name)|psi-mi:cheY(display_short)|uniprotkb:b1882(locus name)|uniprotkb:JW1871(locus name) psi-mi:chea_ecoli(display_long)|uniprotkb:cheA(gene name)|psi-mi:cheA(display_short)|uniprotkb:b1888(locus name)|uniprotkb:JW1877(locus name) psi-mi:"MI:0841"(phosphotransferase assay) Thakor et al. (2011) pubmed:21642453|imex:IM-18408 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0844"(phosphotransfer reaction) psi-mi:"MI:0903"(mpidb) intact:EBI-6414953|mpidb:MPIDB-INT-1632|imex:IM-18408-2 - - psi-mi:"MI:0843"(phosphate acceptor) psi-mi:"MI:0842"(phosphate donor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_416396.1|rcsb pdb:3RVQ|rcsb pdb:3RVR|rcsb pdb:3RVP|rcsb pdb:3RVS|rcsb pdb:5CHY|rcsb pdb:5D2C|rcsb pdb:5DGC|rcsb pdb:5DKF|rcsb pdb:6CHY|rcsb pdb:6TG7|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0043052"(thermotaxis)|go:"GO:0097588"(archaeal or bacterial-type flagellum-dependent cell motility)|go:"GO:1902021"(regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|rcsb pdb:1A0O|rcsb pdb:1AB5|rcsb pdb:1AB6|rcsb pdb:1BDJ|rcsb pdb:1C4W|rcsb pdb:1CEY|rcsb pdb:1CHN|rcsb pdb:1CYE|rcsb pdb:1D4Z|rcsb pdb:1DJM|rcsb pdb:1E6K|ensemblbacteria:AAC74952(transcript)|ensemblbacteria:b1882(gene)|ensemblbacteria:BAA15698(gene)|ensemblbacteria:BAA15698(transcript)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006473"(protein acetylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0009454"(aerotaxis)|rcsb pdb:1E6M|rcsb pdb:1EAY|rcsb pdb:1EHC|rcsb pdb:1F4V|rcsb pdb:1FFG|rcsb pdb:1FFS|rcsb pdb:1FFW|rcsb pdb:1FQW|rcsb pdb:1HEY|rcsb pdb:1JBE|rcsb pdb:1KMI|rcsb pdb:1MIH|rcsb pdb:1U8T|rcsb pdb:1UDR|rcsb pdb:1VLZ|rcsb pdb:1YMU|rcsb pdb:1YMV|rcsb pdb:1ZDM|rcsb pdb:1E6L|rcsb pdb:2B1J|rcsb pdb:2ID9|rcsb pdb:2IDM|rcsb pdb:2LP4|rcsb pdb:3CHY|rcsb pdb:3F7N|rcsb pdb:3FFT|rcsb pdb:3FFW|rcsb pdb:3FFX|rcsb pdb:3FGZ|rcsb pdb:3MYY|rcsb pdb:3OLV|rcsb pdb:3OLW|rcsb pdb:2ID7|rcsb pdb:3OLX|rcsb pdb:3OLY|rcsb pdb:3OO0|rcsb pdb:3OO1|rcsb pdb:3RVJ|rcsb pdb:3RVK|rcsb pdb:3RVL|rcsb pdb:3RVM|rcsb pdb:3RVN|rcsb pdb:3RVO|refseq:WP_000763867.1|dip:DIP-6052N refseq:NP_416402.1|refseq:WP_001350517.1|go:"GO:0018106"(peptidyl-histidine phosphorylation)|ensemblbacteria:AAC74958(transcript)|ensemblbacteria:b1888(gene)|ensemblbacteria:BAA15709(gene)|ensemblbacteria:BAA15709(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009454"(aerotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0031400"(negative regulation of protein modification process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051649"(establishment of localization in cell)|go:"GO:0098561"(methyl accepting chemotaxis protein complex)|go:"GO:1901875"(positive regulation of post-translational protein modification)|go:"GO:1902021"(regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR002545(CheW-like protein)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR004105(Signal transduction histidine kinase, subgroup, homodimeric)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR015162(CheY binding)|interpro:IPR035891|interpro:IPR036061|interpro:IPR036097|interpro:IPR036641|interpro:IPR036890|interpro:IPR037006|rcsb pdb:1A0O|rcsb pdb:1EAY|rcsb pdb:1FFG|rcsb pdb:1FFS|rcsb pdb:1FFW|rcsb pdb:1FWP|rcsb pdb:2LP4|rcsb pdb:6S1K|go:"GO:0043052"(thermotaxis)|dip:DIP-6053N - - - figure legend:figure 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/30 2014/10/16 rogid:EoFDVZXPdOaGEg95ZcoWDMJ/s5483333 rogid:MaWjRuIBsLU60/MZQvfGN+pRyAU83333 intact-crc:77D02F8B5C6151F1|rigid:4+nGmCGoEiiqIpAgvp5HQMIBkz4 false - phosphorylated residue:?-?|mutation decreasing interaction rate:214-214 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)