#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q60I23 uniprotkb:Q9Z2D8 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-1994548|uniprotkb:Q792D3|uniprotkb:Q8CFJ1|ensembl:ENSMUSP00000089948 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:mbd3_mouse(display_long)|uniprotkb:Mbd3(gene name)|psi-mi:Mbd3(display_short)|uniprotkb:Methyl-CpG-binding protein MBD3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001293072.1|refseq:NP_038623.1|dip:DIP-46518N|ensembl:ENSMUSG00000035478(gene)|ensembl:ENSMUST00000092295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0048568"(embryonic organ development)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|interpro:IPR037965|mint:Q9Z2D8|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|go:"GO:0009888"(tissue development) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:1S5pGUEMFTEmqCNFTaaCgZFxG4E10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q6PDG5 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-3870565|uniprotkb:Q6P6P3|ensembl:ENSMUSP00000100868 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:smrc2_mouse(display_long)|uniprotkb:Smarcc2(gene name)|psi-mi:Smarcc2(display_short)|uniprotkb:Baf170(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001107568.1|refseq:NP_001107569.1|refseq:NP_937803.1|dip:DIP-48884N|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0042393"(histone binding)|ensembl:ENSMUSG00000025369(gene)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q6PDG5|reactome:R-MMU-3214858|reactome:R-MMU-8939243|ensembl:ENSMUST00000105235(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:v8cjo/1nUFl5vd96cKMcY8LA8M010090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9WTM5 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-2549911|ensembl:ENSMUSP00000103400|ensembl:ENSMUSP00000147502 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:ruvb2_mouse(display_long)|uniprotkb:Ruvbl2(gene name)|psi-mi:Ruvbl2(display_short)|uniprotkb:p47 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000003868(gene)|ensembl:ENSMUST00000107771(transcript)|ensembl:ENSMUST00000211214(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051117"(ATPase binding)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9WTM5|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:NP_035434.1|refseq:XP_006540785.1|refseq:XP_006540786.1 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:tHnjngaz5qWy9sPXagFLp3TRDtA10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9Z2N8 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-2942759|ensembl:ENSMUSP00000029214|uniprotkb:Q8C1W3|uniprotkb:Q99M56 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:acl6a_mouse(display_long)|uniprotkb:Actl6a(gene name)|psi-mi:Actl6a(display_short)|uniprotkb:Actl6(gene name synonym)|uniprotkb:Baf53a(gene name synonym)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000027671(gene)|ensembl:ENSMUST00000029214(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:Q9Z2N8|reactome:R-MMU-3214858|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8939243|go:"GO:0007399"(nervous system development)|refseq:NP_062647.2 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:a0spTksUhZbdXCOGGaNvsL997Vk10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q8CHY6 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-3043877|ensembl:ENSMUSP00000112164|ensembl:ENSMUSP00000148474|uniprotkb:Q8BTQ2|uniprotkb:Q8VEC9 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:p66a_mouse(display_long)|uniprotkb:Gatad2a(gene name)|psi-mi:Gatad2a(display_short)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000036180(gene)|ensembl:ENSMUST00000116463(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001842"(neural fold formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0012501"(programmed cell death)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0021506"(anterior neuropore closure)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR032346|interpro:IPR040386|mint:Q8CHY6|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|ensembl:ENSMUST00000212478(transcript)|refseq:XP_011240597.1|refseq:NP_001106817.1 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:Sl8kjbcfcvx+CKED3wLD9HvAEjs10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q6PDQ2 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-3043852|ensembl:ENSMUSP00000060054 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q60973 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-302297|ensembl:ENSMUSP00000033720|uniprotkb:Q3UX20|uniprotkb:A2AFJ0 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:rbbp7_mouse(display_long)|uniprotkb:Rbbp7(gene name)|psi-mi:Rbbp7(display_short)|uniprotkb:Rbap46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q60973|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-606279|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-8951664|reactome:R-MMU-8953750|ensembl:ENSMUSG00000031353(gene)|ensembl:ENSMUST00000033720(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_033057.3|dip:DIP-32856N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:+OV9hWS13A8fAypZJAXf656Z25U10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P09021 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-925394|uniprotkb:Q91VQ5|ensembl:ENSMUSP00000039012 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:hxa5_mouse(display_long)|uniprotkb:Hoxa5(gene name)|psi-mi:Hoxa5(display_short)|uniprotkb:Hox-1.3(gene name synonym)|uniprotkb:Hoxa-5(gene name synonym)|uniprotkb:Homeobox protein Hox-1.3(gene name synonym)|uniprotkb:Homeobox protein M2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_034583.1|ensembl:ENSMUSG00000038253(gene)|ensembl:ENSMUST00000048794(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030324"(lung development)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060435"(bronchiole development)|go:"GO:0060439"(trachea morphogenesis)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060481"(lobar bronchus epithelium development)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P09021 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:1/djC9dlDssHzy1+X3zilRD+NPs10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q8BHJ5 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-1216384|uniprotkb:Q3UWL6|uniprotkb:Q8CBG4|uniprotkb:Q8VEG3|uniprotkb:Q9EQD4|ensembl:ENSMUSP00000067164|ensembl:ENSMUSP00000141363|ensembl:ENSMUSP00000142184|ensembl:ENSMUSP00000144436 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:tbl1r_mouse(display_long)|uniprotkb:Tbl1xr1(gene name)|psi-mi:Tbl1xr1(display_short)|uniprotkb:Ira1(gene name synonym)|uniprotkb:Tblr1(gene name synonym)|uniprotkb:Transducin beta-like 1X-related protein 1(gene name synonym)|uniprotkb:Nuclear receptor corepressor/HDAC3 complex subunit TBLR1(gene name synonym)|uniprotkb:TBL1-related protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_109657.2|refseq:XP_011248020.1|refseq:XP_011248023.1|refseq:XP_011248021.1|refseq:XP_006535642.1|refseq:XP_006535643.1|refseq:XP_017175306.1|dip:DIP-38606N|ensembl:ENSMUSG00000027630(gene)|ensembl:ENSMUST00000063988(transcript)|ensembl:ENSMUST00000192328(transcript)|ensembl:ENSMUST00000193734(transcript)|ensembl:ENSMUST00000202747(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002021"(response to dietary excess)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q8BHJ5|rcsb pdb:5NAF|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:yq19+P14lXTgaMDi8JXFd5B2dic10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q80YV3 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9ESJ0 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6122886|uniprotkb:E9QLH3|uniprotkb:Q6ZPJ4|ensembl:ENSMUSP00000086909 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:xpo4_mouse(display_long)|uniprotkb:Xpo4(gene name)|psi-mi:Xpo4(display_short)|uniprotkb:Kiaa1721(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_065252.1|ensembl:ENSMUSG00000021952(gene)|ensembl:ENSMUST00000089482(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|rcsb pdb:5DLQ go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:E81V4/gVadqPD5hvLHeFnEbavkc10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P97496 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-648047|uniprotkb:Q7TS80|uniprotkb:Q7TT29|ensembl:ENSMUSP00000086094 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:smrc1_mouse(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym)|uniprotkb:SWI3-related protein(gene name synonym)|uniprotkb:Smarcc1(gene name)|psi-mi:Smarcc1(display_short)|uniprotkb:Baf155(gene name synonym)|uniprotkb:Srg3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_033237.2|dip:DIP-39986N|ensembl:ENSMUSG00000032481(gene)|ensembl:ENSMUST00000088716(transcript)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006323"(DNA packaging)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:P97496|reactome:R-MMU-3214858|reactome:R-MMU-8939243 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:yhuZC6SRcw/jSKI2+nruFD+QqlE10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q60972 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-302291|uniprotkb:A2A875|ensembl:ENSMUSP00000099658 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:rbbp4_mouse(display_long)|uniprotkb:Rbbp4(gene name)|psi-mi:Rbbp4(display_short)|uniprotkb:Rbap48(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000057236(gene)|ensembl:ENSMUST00000102598(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q60972|reactome:R-MMU-1538133|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-606279|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-8953750|refseq:NP_033056.2|dip:DIP-32855N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q920B9 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-2549823|uniprotkb:Q3TZ48|uniprotkb:Q3UFH0|uniprotkb:Q921H4 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:sp16h_mouse(display_long)|uniprotkb:Supt16h(gene name)|psi-mi:Supt16h(display_short)|uniprotkb:Fact140(gene name synonym)|uniprotkb:Factp140(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:Supt16(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6796648|interpro:IPR029148|reactome:R-MMU-6804756|reactome:R-MMU-75955|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|refseq:NP_291096.2|dip:DIP-55972N|mint:Q920B9 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:qcl0ckY0w3tIem/ezLyPtHVUnZA10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:A4QPD1 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6122952 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:a4qpd1_mouse(display_long)|uniprotkb:Zeb1(gene name)|psi-mi:Zeb1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 interpro:IPR036236|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR008598(Drought induced 19)|go:"GO:0003677"(DNA binding) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:zFbZ+kA/cMb5CRUnlnwloiCSLGE10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:A1L3S7 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-5668275|ensembl:ENSMUSP00000143085 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:a1l3s7_mouse(display_long)|uniprotkb:Gatad2b(gene name)|psi-mi:Gatad2b(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000042390(gene)|ensembl:ENSMUST00000197988(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:BJjSQWHfPsqJNYrmy06aaf6tYjY10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P60122 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-1634999|uniprotkb:O35753|ensembl:ENSMUSP00000032165 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:ruvb1_mouse(display_long)|uniprotkb:Ruvbl1(gene name)|psi-mi:Ruvbl1(display_short)|uniprotkb:Tip49(gene name synonym)|uniprotkb:Tip49a(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:DNA helicase p50(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_062659.1|ensembl:ENSMUSG00000030079(gene)|ensembl:ENSMUST00000032165(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:P60122|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-5696394|reactome:R-MMU-606279 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:fZiQ7AurvKII0LYc+haBswAXfZ410090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q62255 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-3043962|uniprotkb:Q08EB0|uniprotkb:Q52KR5|uniprotkb:Q6GQT8|uniprotkb:Q8BRD9 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:sall3_mouse(display_long)|uniprotkb:Sall3(gene name)|psi-mi:Sall3(display_short)|uniprotkb:Sal(gene name synonym)|uniprotkb:MSal(gene name synonym)|uniprotkb:Spalt-like protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|refseq:NP_840064.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q62255|interpro:IPR036236 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:vXrmUg8gZgQAtfHxHzVtqrZL/QQ10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:O09106 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-301912|uniprotkb:P97476|ensembl:ENSMUSP00000099657 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:hdac1_mouse(display_long)|uniprotkb:Hdac1(gene name)|psi-mi:Hdac1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 dip:DIP-31499N|ensembl:ENSMUSG00000028800(gene)|ensembl:ENSMUST00000102597(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_032254.1|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O09106|reactome:R-MMU-1538133|reactome:R-MMU-201722|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-3769402|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8936459|reactome:R-MMU-8943724|reactome:R-MMU-9018519|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0001046"(core promoter sequence-specific DNA binding) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:P7QV++FiMiNcabUkswbnNhGVU3410090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:A7UQY4 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123007 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:a7uqy4_mouse(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 interpro:IPR035979|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001155889.1|refseq:NP_001155890.1|refseq:NP_034982.2|interpro:IPR034630|interpro:IPR034631|interpro:IPR034632|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:hDX85NFLJmcMvr5EuXhCXDLGDzw10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P97863 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6122967|uniprotkb:P70252|uniprotkb:P70253|uniprotkb:P70254|uniprotkb:Q9R1G4|ensembl:ENSMUSP00000052863 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:nfib_mouse(display_long)|uniprotkb:Nfib(gene name)|psi-mi:Nfib(display_short)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:Nuclear factor I/B(gene name synonym)|uniprotkb:TGGCA-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001106680.1|refseq:NP_032713.3|ensembl:ENSMUSG00000008575(gene)|ensembl:ENSMUST00000050872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021960"(anterior commissure morphogenesis)|go:"GO:0030324"(lung development)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0060689"(cell differentiation involved in salivary gland development)|go:"GO:0061141"(lung ciliated cell differentiation)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000791"(negative regulation of mesenchymal cell proliferation involved in lung development)|go:"GO:2000795"(negative regulation of epithelial cell proliferation involved in lung morphogenesis)|interpro:IPR000647(CTF/NF-I)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR019548|interpro:IPR019739|interpro:IPR020604|mint:P97863|go:"GO:0001650"(fibrillar center) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:q+27AZuN224n0dbYoogA7/JIZ7g10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q60520 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-349034|uniprotkb:Q60820|uniprotkb:Q62139|uniprotkb:Q62140|uniprotkb:Q7TPU8|uniprotkb:Q7TSZ2|ensembl:ENSMUSP00000045044|ensembl:ENSMUSP00000126601|ensembl:ENSMUSP00000130641|uniprotkb:Q570Z7 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:sin3a_mouse(display_long)|uniprotkb:Sin3a(gene name)|psi-mi:Sin3a(display_short)|uniprotkb:Kiaa4126(gene name synonym)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001103820.1|refseq:NP_001103821.1|refseq:NP_035508.2|ensembl:ENSMUSG00000042557(gene)|ensembl:ENSMUST00000049169(transcript)|ensembl:ENSMUST00000167715(transcript)|ensembl:ENSMUST00000168678(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|rcsb pdb:2RMS|reactome:R-MMU-3899300|reactome:R-MMU-400206|reactome:R-MMU-8936459|reactome:R-MMU-9022692|reactome:R-MMU-9707564|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q60520|rcsb pdb:1G1E|rcsb pdb:1S5Q|rcsb pdb:1S5R|rcsb pdb:2L9S|rcsb pdb:2LD7|rcsb pdb:2N2H|rcsb pdb:2RMR|refseq:XP_011240985.1|refseq:XP_011240986.1|refseq:XP_011240987.1|refseq:XP_011240988.1|refseq:XP_017168720.1|refseq:XP_006510953.1|refseq:XP_006510954.1|refseq:XP_006510955.1|refseq:XP_006510956.1|dip:DIP-469N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:xd+Wh6NZxejENeiSl5WRDOrVDtc10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:A2BH40 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-371499|uniprotkb:Q640Q1|uniprotkb:Q925Q1|ensembl:ENSMUSP00000101517 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:ari1a_mouse(display_long)|uniprotkb:Arid1a(gene name)|psi-mi:Arid1a(display_short)|uniprotkb:Baf250(gene name synonym)|uniprotkb:Baf250a(gene name synonym)|uniprotkb:Osa1(gene name synonym)|uniprotkb:Smarcf1(gene name synonym)|uniprotkb:SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1(gene name synonym)|uniprotkb:SWI/SNF complex protein p270(gene name synonym)|uniprotkb:SWI-like protein(gene name synonym)|uniprotkb:Osa homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 250(gene name synonym)|uniprotkb:BRG1-associated factor 250a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001074288.1|refseq:XP_006539390.1|interpro:IPR001606(AT-rich interaction region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021906|interpro:IPR030094|interpro:IPR033388|interpro:IPR036431|mint:A2BH40|reactome:R-MMU-3214858|reactome:R-MMU-8939243|go:"GO:0071565"(nBAF complex)|go:"GO:1901998"(toxin transport)|ensembl:ENSMUSG00000007880(gene)|ensembl:ENSMUST00000105897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001843"(neural tube closure)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0003408"(optic cup formation involved in camera-type eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007566"(embryo implantation)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0035060"(brahma complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0071564"(npBAF complex)|dip:DIP-58952N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:MusGr/BftB3D49ETE1DK7LU7SCM10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P53564 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-642309|uniprotkb:O08994|uniprotkb:P70301|uniprotkb:Q571L6|uniprotkb:Q91ZD2 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:cux1_mouse(display_long)|uniprotkb:CCAAT displacement protein(gene name synonym)|uniprotkb:Homeobox protein cux-1(gene name synonym)|uniprotkb:Kiaa4047(gene name synonym)|uniprotkb:Cux1(gene name)|psi-mi:Cux1(display_short)|uniprotkb:Cux(gene name synonym)|uniprotkb:Cutl1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|mint:P53564|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030324"(lung development)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0043005"(neuron projection)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|refseq:NP_001278162.1|refseq:NP_001278163.1|refseq:NP_034116.3 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:XozohEVVgGk0JJ5Qaw2AmPO+dHI10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:F8WHY8 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6120213|ensembl:ENSMUSP00000064338|ensembl:ENSMUSP00000105348 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:f8why8_mouse(display_long)|uniprotkb:Mta1(gene name)|psi-mi:Mta1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_473422.2|ensembl:ENSMUSG00000021144(gene)|ensembl:ENSMUST00000069690(transcript)|ensembl:ENSMUST00000109726(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|interpro:IPR043151|mint:F8WHY8 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:bSJVhbyNmLEmXNhRG9rkgV0Wj+s10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P70288 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-302251|uniprotkb:B2RRP3 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:bGLIDKTlyhBz40NViC8calRacZ010090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:A2AJK6 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:F8VQL9 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6120544|ensembl:ENSMUSP00000107033 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:f8vql9_mouse(display_long)|uniprotkb:Ncor2(gene name)|psi-mi:Ncor2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:XP_011239130.1|ensembl:ENSMUSG00000029478(gene)|ensembl:ENSMUST00000111402(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0007595"(lactation)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:2rW2VJP1VRozK4Mbrihyk6WfThQ10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9R190 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-904134|uniprotkb:Q3TVT8|ensembl:ENSMUSP00000093959 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:mta2_mouse(display_long)|uniprotkb:Mta2(gene name)|psi-mi:Mta2(display_short)|uniprotkb:Mta1l1(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123027|imex:IM-17312-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_035972.3|dip:DIP-36630N|ensembl:ENSMUSG00000071646(gene)|ensembl:ENSMUST00000096240(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006323"(DNA packaging)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:Q9R190|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:iHG+WZKTCRwTvC7LdS7OayvcEuA10090 intact-crc:E85FACD070174E60|rigid:BklYXBrt5tkYx06cX4Nhjpx9kyg false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:Q6PDG5 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-3870565|uniprotkb:Q6P6P3|ensembl:ENSMUSP00000100868 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:smrc2_mouse(display_long)|uniprotkb:Smarcc2(gene name)|psi-mi:Smarcc2(display_short)|uniprotkb:Baf170(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 refseq:NP_001107568.1|refseq:NP_001107569.1|refseq:NP_937803.1|dip:DIP-48884N|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0042393"(histone binding)|ensembl:ENSMUSG00000025369(gene)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q6PDG5|reactome:R-MMU-3214858|reactome:R-MMU-8939243|ensembl:ENSMUST00000105235(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding) go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:v8cjo/1nUFl5vd96cKMcY8LA8M010090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:A2BH40-4 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-6123711|ensembl:ENSMUSP00000008024 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:a2bh40-4(display_long)|uniprotkb:Arid1a(gene name)|psi-mi:Arid1a(display_short)|uniprotkb:Baf250(gene name synonym)|uniprotkb:Baf250a(gene name synonym)|uniprotkb:Osa1(gene name synonym)|uniprotkb:Smarcf1(gene name synonym)|uniprotkb:BRG1-associated factor 250(gene name synonym)|uniprotkb:BRG1-associated factor 250a(gene name synonym)|uniprotkb:Osa homolog 1(gene name synonym)|uniprotkb:SWI-like protein(gene name synonym)|uniprotkb:SWI/SNF complex protein p270(gene name synonym)|uniprotkb:SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 intact:EBI-371499(isoform-parent)|ensembl:ENSMUSG00000007880(gene)|ensembl:ENSMUST00000008024(transcript) go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:L2pcCJLWwSsvfmIA8yoAKtpdcUU10090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:Q9JKN5 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-1213712|ensembl:ENSMUSP00000061408 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:olig1_mouse(display_long)|uniprotkb:Olig1(gene name)|psi-mi:Olig1(display_short)|uniprotkb:Oligodendrocyte-specific bHLH transcription factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 refseq:NP_058664.2|ensembl:ENSMUSG00000046160(gene)|ensembl:ENSMUST00000056882(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048663"(neuron fate commitment)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032657|interpro:IPR036638|mint:Q9JKN5 go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:1R93ekMg/uZq5unF9PJGlf/iiJ810090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:Q8CHY6 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-3043877|ensembl:ENSMUSP00000112164|ensembl:ENSMUSP00000148474|uniprotkb:Q8BTQ2|uniprotkb:Q8VEC9 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:p66a_mouse(display_long)|uniprotkb:Gatad2a(gene name)|psi-mi:Gatad2a(display_short)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 ensembl:ENSMUSG00000036180(gene)|ensembl:ENSMUST00000116463(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001842"(neural fold formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0012501"(programmed cell death)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0021506"(anterior neuropore closure)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR032346|interpro:IPR040386|mint:Q8CHY6|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|ensembl:ENSMUST00000212478(transcript)|refseq:XP_011240597.1|refseq:NP_001106817.1 go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:Sl8kjbcfcvx+CKED3wLD9HvAEjs10090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:F8WHY8 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-6120213|ensembl:ENSMUSP00000064338|ensembl:ENSMUSP00000105348 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:f8why8_mouse(display_long)|uniprotkb:Mta1(gene name)|psi-mi:Mta1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 refseq:NP_473422.2|ensembl:ENSMUSG00000021144(gene)|ensembl:ENSMUST00000069690(transcript)|ensembl:ENSMUST00000109726(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|interpro:IPR043151|mint:F8WHY8 go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:bSJVhbyNmLEmXNhRG9rkgV0Wj+s10090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:Q60I23 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-6120118|ensembl:ENSMUSP00000096755 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:Q9Z1Q9 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-6123642|uniprotkb:Q9QUN2|ensembl:ENSMUSP00000084572 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:syvc_mouse(display_long)|uniprotkb:Vars1(gene name)|psi-mi:Vars1(display_short)|uniprotkb:Bat6(gene name synonym)|uniprotkb:G7a(gene name synonym)|uniprotkb:Protein G7a(gene name synonym)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)|uniprotkb:Vars(gene name synonym)|uniprotkb:Vars2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 refseq:NP_035820.3|refseq:XP_017172884.1|ensembl:ENSMUSG00000007029(gene)|ensembl:ENSMUST00000087315(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004832"(valine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006438"(valyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033705|interpro:IPR036282|interpro:IPR037118|mint:Q9Z1Q9 go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:gAbY8qZ5vHpLxCj9zbBarjEd1hk10090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:Q3TKT4-2 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-6123671|ensembl:ENSMUSP00000034707 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:q3tkt4-2(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 intact:EBI-1210244(isoform-parent)|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000034707(transcript) go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:f0nzvEfB/PVyjv/F3PwgrtUHs4Q10090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:Q62255 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-3043962|uniprotkb:Q08EB0|uniprotkb:Q52KR5|uniprotkb:Q6GQT8|uniprotkb:Q8BRD9 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:sall3_mouse(display_long)|uniprotkb:Sall3(gene name)|psi-mi:Sall3(display_short)|uniprotkb:Sal(gene name synonym)|uniprotkb:MSal(gene name synonym)|uniprotkb:Spalt-like protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|refseq:NP_840064.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q62255|interpro:IPR036236 go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:vXrmUg8gZgQAtfHxHzVtqrZL/QQ10090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:O54941 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-642789|uniprotkb:Q8BPD9|ensembl:ENSMUSP00000099422 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:smce1_mouse(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:Smarce1(gene name)|psi-mi:Smarce1(display_short)|uniprotkb:Baf57(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 refseq:NP_065643.1|ensembl:ENSMUSG00000037935(gene)|ensembl:ENSMUST00000103133(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:O54941|reactome:R-MMU-3214858|reactome:R-MMU-8939243|go:"GO:0003677"(DNA binding)|dip:DIP-39985N go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:W5MLVNJ0Jj6hoGwVy2E2HzKx/fY10090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:Q9QZF3 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-6123686 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:q9qzf3_mouse(display_long)|uniprotkb:Zbtb20(gene name)|psi-mi:Zbtb20(display_short)|uniprotkb:Zfp288(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 mint:Q9QZF3|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:BAXhPyXefH1dTQqud8/cb82OYZA10090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2AJK6 uniprotkb:Q9R190 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-904134|uniprotkb:Q3TVT8|ensembl:ENSMUSP00000093959 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:mta2_mouse(display_long)|uniprotkb:Mta2(gene name)|psi-mi:Mta2(display_short)|uniprotkb:Mta1l1(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123638|imex:IM-17312-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 refseq:NP_035972.3|dip:DIP-36630N|ensembl:ENSMUSG00000071646(gene)|ensembl:ENSMUST00000096240(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006323"(DNA packaging)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:Q9R190|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724 go:"GO:0005634"(nucleus) - - figure legend:Table 2, Supplementary Table 3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/12/08 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:iHG+WZKTCRwTvC7LdS7OayvcEuA10090 intact-crc:F501581FFD462558|rigid:e+/d0hGYbyEgdL8byzOW5wjH+4k false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9Z2D8 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-1994548|uniprotkb:Q792D3|uniprotkb:Q8CFJ1|ensembl:ENSMUSP00000089948 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:mbd3_mouse(display_long)|uniprotkb:Mbd3(gene name)|psi-mi:Mbd3(display_short)|uniprotkb:Methyl-CpG-binding protein MBD3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001293072.1|refseq:NP_038623.1|dip:DIP-46518N|ensembl:ENSMUSG00000035478(gene)|ensembl:ENSMUST00000092295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0048568"(embryonic organ development)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|interpro:IPR037965|mint:Q9Z2D8|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|go:"GO:0009888"(tissue development) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:1S5pGUEMFTEmqCNFTaaCgZFxG4E10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9Z0H3 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-689365|ensembl:ENSMUSP00000000925 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:snf5_mouse(display_long)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:Smarcb1(gene name)|psi-mi:Smarcb1(display_short)|uniprotkb:Ini1(gene name synonym)|uniprotkb:Snf5l1(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:Baf47(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_035548.1|dip:DIP-34373N|ensembl:ENSMUSG00000000902(gene)|ensembl:ENSMUST00000000925(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001824"(blastocyst development)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|mint:Q9Z0H3|reactome:R-MMU-3214858|reactome:R-MMU-8939243 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q6PDG5 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-3870565|uniprotkb:Q6P6P3|ensembl:ENSMUSP00000100868 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:smrc2_mouse(display_long)|uniprotkb:Smarcc2(gene name)|psi-mi:Smarcc2(display_short)|uniprotkb:Baf170(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001107568.1|refseq:NP_001107569.1|refseq:NP_937803.1|dip:DIP-48884N|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0042393"(histone binding)|ensembl:ENSMUSG00000025369(gene)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q6PDG5|reactome:R-MMU-3214858|reactome:R-MMU-8939243|ensembl:ENSMUST00000105235(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:v8cjo/1nUFl5vd96cKMcY8LA8M010090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9JM08 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123320 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:q9jm08_mouse(display_long)|uniprotkb:Hdac3(gene name)|psi-mi:Hdac3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 interpro:IPR037138|interpro:IPR023696|refseq:NP_034541.2|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023801|go:"GO:0005634"(nucleus)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0046872"(metal ion binding) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:kg9iZAooFeAlHvrqknDQpLdbT5I10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P09021 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-925394|uniprotkb:Q91VQ5|ensembl:ENSMUSP00000039012 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:hxa5_mouse(display_long)|uniprotkb:Hoxa5(gene name)|psi-mi:Hoxa5(display_short)|uniprotkb:Hox-1.3(gene name synonym)|uniprotkb:Hoxa-5(gene name synonym)|uniprotkb:Homeobox protein Hox-1.3(gene name synonym)|uniprotkb:Homeobox protein M2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_034583.1|ensembl:ENSMUSG00000038253(gene)|ensembl:ENSMUST00000048794(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030324"(lung development)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0060435"(bronchiole development)|go:"GO:0060439"(trachea morphogenesis)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060481"(lobar bronchus epithelium development)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P09021 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:1/djC9dlDssHzy1+X3zilRD+NPs10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:A7UQY4 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123007 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:a7uqy4_mouse(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 interpro:IPR035979|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001155889.1|refseq:NP_001155890.1|refseq:NP_034982.2|interpro:IPR034630|interpro:IPR034631|interpro:IPR034632|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:hDX85NFLJmcMvr5EuXhCXDLGDzw10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9ESJ0 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6122886|uniprotkb:E9QLH3|uniprotkb:Q6ZPJ4|ensembl:ENSMUSP00000086909 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:xpo4_mouse(display_long)|uniprotkb:Xpo4(gene name)|psi-mi:Xpo4(display_short)|uniprotkb:Kiaa1721(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_065252.1|ensembl:ENSMUSG00000021952(gene)|ensembl:ENSMUST00000089482(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|rcsb pdb:5DLQ go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:E81V4/gVadqPD5hvLHeFnEbavkc10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P97863 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6122967|uniprotkb:P70252|uniprotkb:P70253|uniprotkb:P70254|uniprotkb:Q9R1G4|ensembl:ENSMUSP00000052863 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:nfib_mouse(display_long)|uniprotkb:Nfib(gene name)|psi-mi:Nfib(display_short)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:Nuclear factor I/B(gene name synonym)|uniprotkb:TGGCA-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001106680.1|refseq:NP_032713.3|ensembl:ENSMUSG00000008575(gene)|ensembl:ENSMUST00000050872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021960"(anterior commissure morphogenesis)|go:"GO:0030324"(lung development)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0060689"(cell differentiation involved in salivary gland development)|go:"GO:0061141"(lung ciliated cell differentiation)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000791"(negative regulation of mesenchymal cell proliferation involved in lung development)|go:"GO:2000795"(negative regulation of epithelial cell proliferation involved in lung morphogenesis)|interpro:IPR000647(CTF/NF-I)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR019548|interpro:IPR019739|interpro:IPR020604|mint:P97863|go:"GO:0001650"(fibrillar center) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:q+27AZuN224n0dbYoogA7/JIZ7g10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P53564 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-642309|uniprotkb:O08994|uniprotkb:P70301|uniprotkb:Q571L6|uniprotkb:Q91ZD2 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:cux1_mouse(display_long)|uniprotkb:CCAAT displacement protein(gene name synonym)|uniprotkb:Homeobox protein cux-1(gene name synonym)|uniprotkb:Kiaa4047(gene name synonym)|uniprotkb:Cux1(gene name)|psi-mi:Cux1(display_short)|uniprotkb:Cux(gene name synonym)|uniprotkb:Cutl1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|mint:P53564|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030324"(lung development)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0043005"(neuron projection)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|refseq:NP_001278162.1|refseq:NP_001278163.1|refseq:NP_034116.3 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:XozohEVVgGk0JJ5Qaw2AmPO+dHI10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:A4QPD1 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6122952 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:a4qpd1_mouse(display_long)|uniprotkb:Zeb1(gene name)|psi-mi:Zeb1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 interpro:IPR036236|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR008598(Drought induced 19)|go:"GO:0003677"(DNA binding) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:zFbZ+kA/cMb5CRUnlnwloiCSLGE10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:A2AJK6 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q920B9 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-2549823|uniprotkb:Q3TZ48|uniprotkb:Q3UFH0|uniprotkb:Q921H4 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:sp16h_mouse(display_long)|uniprotkb:Supt16h(gene name)|psi-mi:Supt16h(display_short)|uniprotkb:Fact140(gene name synonym)|uniprotkb:Factp140(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:Supt16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-6796648|interpro:IPR029148|reactome:R-MMU-6804756|reactome:R-MMU-75955|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|refseq:NP_291096.2|dip:DIP-55972N|mint:Q920B9 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:qcl0ckY0w3tIem/ezLyPtHVUnZA10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:F8VQL9 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6120544|ensembl:ENSMUSP00000107033 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:f8vql9_mouse(display_long)|uniprotkb:Ncor2(gene name)|psi-mi:Ncor2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:XP_011239130.1|ensembl:ENSMUSG00000029478(gene)|ensembl:ENSMUST00000111402(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0007595"(lactation)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:2rW2VJP1VRozK4Mbrihyk6WfThQ10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P48381 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123284|uniprotkb:Q8BLW2|uniprotkb:Q8C0R3|uniprotkb:Q8VBY6|ensembl:ENSMUSP00000126313|ensembl:ENSMUSP00000133461|ensembl:ENSMUSP00000134141 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:rfx3_mouse(display_long)|uniprotkb:Rfx3(gene name)|psi-mi:Rfx3(display_short)|uniprotkb:Regulatory factor X 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:XP_011245471.1|refseq:NP_001159886.1|refseq:NP_035395.2|refseq:XP_006526845.1|ensembl:ENSMUSG00000040929(gene)|ensembl:ENSMUST00000165566(transcript)|ensembl:ENSMUST00000172907(transcript)|ensembl:ENSMUST00000174850(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060271"(cilium assembly)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0072560"(type B pancreatic cell maturation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|mint:P48381 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:n61SA45VD1vA0KpE7K2juAkIOIw10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P30051 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-3953905 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:tead1_mouse(display_long)|uniprotkb:Tead1(gene name)|psi-mi:Tead1(display_short)|uniprotkb:Tcf13(gene name synonym)|uniprotkb:Tef-1(gene name synonym)|uniprotkb:Tef1(gene name synonym)|uniprotkb:NTEF-1(gene name synonym)|uniprotkb:Protein GT-IIC(gene name synonym)|uniprotkb:TEA domain family member 1(gene name synonym)|uniprotkb:Transcription factor 13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0030903"(notochord development)|go:"GO:0007507"(heart development)|go:"GO:0035329"(hippo signaling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|interpro:IPR038096|interpro:IPR041086|dip:DIP-41748N|reactome:R-MMU-2032785|reactome:R-MMU-8951671 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:AFA1CEpD1J/A3U2YQSSO8wjqfyE10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9Z2N8 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-2942759|ensembl:ENSMUSP00000029214|uniprotkb:Q8C1W3|uniprotkb:Q99M56 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:acl6a_mouse(display_long)|uniprotkb:Actl6a(gene name)|psi-mi:Actl6a(display_short)|uniprotkb:Actl6(gene name synonym)|uniprotkb:Baf53a(gene name synonym)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000027671(gene)|ensembl:ENSMUST00000029214(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:Q9Z2N8|reactome:R-MMU-3214858|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8939243|go:"GO:0007399"(nervous system development)|refseq:NP_062647.2 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:a0spTksUhZbdXCOGGaNvsL997Vk10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:F8WHY8 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6120213|ensembl:ENSMUSP00000064338|ensembl:ENSMUSP00000105348 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:f8why8_mouse(display_long)|uniprotkb:Mta1(gene name)|psi-mi:Mta1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_473422.2|ensembl:ENSMUSG00000021144(gene)|ensembl:ENSMUST00000069690(transcript)|ensembl:ENSMUST00000109726(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|interpro:IPR043151|mint:F8WHY8 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:bSJVhbyNmLEmXNhRG9rkgV0Wj+s10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P97496 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-648047|uniprotkb:Q7TS80|uniprotkb:Q7TT29|ensembl:ENSMUSP00000086094 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:smrc1_mouse(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym)|uniprotkb:SWI3-related protein(gene name synonym)|uniprotkb:Smarcc1(gene name)|psi-mi:Smarcc1(display_short)|uniprotkb:Baf155(gene name synonym)|uniprotkb:Srg3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_033237.2|dip:DIP-39986N|ensembl:ENSMUSG00000032481(gene)|ensembl:ENSMUST00000088716(transcript)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006323"(DNA packaging)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:P97496|reactome:R-MMU-3214858|reactome:R-MMU-8939243 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:yhuZC6SRcw/jSKI2+nruFD+QqlE10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q60972 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-302291|uniprotkb:A2A875|ensembl:ENSMUSP00000099658 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:rbbp4_mouse(display_long)|uniprotkb:Rbbp4(gene name)|psi-mi:Rbbp4(display_short)|uniprotkb:Rbap48(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000057236(gene)|ensembl:ENSMUST00000102598(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q60972|reactome:R-MMU-1538133|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-606279|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-8953750|refseq:NP_033056.2|dip:DIP-32855N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:A2BH40 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-371499|uniprotkb:Q640Q1|uniprotkb:Q925Q1|ensembl:ENSMUSP00000101517 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:ari1a_mouse(display_long)|uniprotkb:Arid1a(gene name)|psi-mi:Arid1a(display_short)|uniprotkb:Baf250(gene name synonym)|uniprotkb:Baf250a(gene name synonym)|uniprotkb:Osa1(gene name synonym)|uniprotkb:Smarcf1(gene name synonym)|uniprotkb:SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1(gene name synonym)|uniprotkb:SWI/SNF complex protein p270(gene name synonym)|uniprotkb:SWI-like protein(gene name synonym)|uniprotkb:Osa homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 250(gene name synonym)|uniprotkb:BRG1-associated factor 250a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001074288.1|refseq:XP_006539390.1|interpro:IPR001606(AT-rich interaction region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021906|interpro:IPR030094|interpro:IPR033388|interpro:IPR036431|mint:A2BH40|reactome:R-MMU-3214858|reactome:R-MMU-8939243|go:"GO:0071565"(nBAF complex)|go:"GO:1901998"(toxin transport)|ensembl:ENSMUSG00000007880(gene)|ensembl:ENSMUST00000105897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001843"(neural tube closure)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0003408"(optic cup formation involved in camera-type eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007566"(embryo implantation)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0035060"(brahma complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0071564"(npBAF complex)|dip:DIP-58952N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:MusGr/BftB3D49ETE1DK7LU7SCM10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9QYJ0 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-772431|ensembl:ENSMUSP00000034138 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:dnja2_mouse(display_long)|uniprotkb:Dnaja2(gene name)|psi-mi:Dnaja2(display_short)|uniprotkb:mDj3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_062768.1|ensembl:ENSMUSG00000031701(gene)|ensembl:ENSMUST00000034138(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:Q9QYJ0|reactome:R-MMU-3371497 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:ZYn3t1WpFrPa82gsMHxjaQRPr3k10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q60520 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-349034|uniprotkb:Q60820|uniprotkb:Q62139|uniprotkb:Q62140|uniprotkb:Q7TPU8|uniprotkb:Q7TSZ2|ensembl:ENSMUSP00000045044|ensembl:ENSMUSP00000126601|ensembl:ENSMUSP00000130641|uniprotkb:Q570Z7 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:sin3a_mouse(display_long)|uniprotkb:Sin3a(gene name)|psi-mi:Sin3a(display_short)|uniprotkb:Kiaa4126(gene name synonym)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001103820.1|refseq:NP_001103821.1|refseq:NP_035508.2|ensembl:ENSMUSG00000042557(gene)|ensembl:ENSMUST00000049169(transcript)|ensembl:ENSMUST00000167715(transcript)|ensembl:ENSMUST00000168678(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|rcsb pdb:2RMS|reactome:R-MMU-3899300|reactome:R-MMU-400206|reactome:R-MMU-8936459|reactome:R-MMU-9022692|reactome:R-MMU-9707564|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q60520|rcsb pdb:1G1E|rcsb pdb:1S5Q|rcsb pdb:1S5R|rcsb pdb:2L9S|rcsb pdb:2LD7|rcsb pdb:2N2H|rcsb pdb:2RMR|refseq:XP_011240985.1|refseq:XP_011240986.1|refseq:XP_011240987.1|refseq:XP_011240988.1|refseq:XP_017168720.1|refseq:XP_006510953.1|refseq:XP_006510954.1|refseq:XP_006510955.1|refseq:XP_006510956.1|dip:DIP-469N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:xd+Wh6NZxejENeiSl5WRDOrVDtc10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q8BHJ5 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-1216384|uniprotkb:Q3UWL6|uniprotkb:Q8CBG4|uniprotkb:Q8VEG3|uniprotkb:Q9EQD4|ensembl:ENSMUSP00000067164|ensembl:ENSMUSP00000141363|ensembl:ENSMUSP00000142184|ensembl:ENSMUSP00000144436 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:tbl1r_mouse(display_long)|uniprotkb:Tbl1xr1(gene name)|psi-mi:Tbl1xr1(display_short)|uniprotkb:Ira1(gene name synonym)|uniprotkb:Tblr1(gene name synonym)|uniprotkb:Transducin beta-like 1X-related protein 1(gene name synonym)|uniprotkb:Nuclear receptor corepressor/HDAC3 complex subunit TBLR1(gene name synonym)|uniprotkb:TBL1-related protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_109657.2|refseq:XP_011248020.1|refseq:XP_011248023.1|refseq:XP_011248021.1|refseq:XP_006535642.1|refseq:XP_006535643.1|refseq:XP_017175306.1|dip:DIP-38606N|ensembl:ENSMUSG00000027630(gene)|ensembl:ENSMUST00000063988(transcript)|ensembl:ENSMUST00000192328(transcript)|ensembl:ENSMUST00000193734(transcript)|ensembl:ENSMUST00000202747(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002021"(response to dietary excess)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q8BHJ5|rcsb pdb:5NAF|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:yq19+P14lXTgaMDi8JXFd5B2dic10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q62255 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-3043962|uniprotkb:Q08EB0|uniprotkb:Q52KR5|uniprotkb:Q6GQT8|uniprotkb:Q8BRD9 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:sall3_mouse(display_long)|uniprotkb:Sall3(gene name)|psi-mi:Sall3(display_short)|uniprotkb:Sal(gene name synonym)|uniprotkb:MSal(gene name synonym)|uniprotkb:Spalt-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|refseq:NP_840064.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q62255|interpro:IPR036236 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:vXrmUg8gZgQAtfHxHzVtqrZL/QQ10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q8CHY6 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-3043877|ensembl:ENSMUSP00000112164|ensembl:ENSMUSP00000148474|uniprotkb:Q8BTQ2|uniprotkb:Q8VEC9 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:p66a_mouse(display_long)|uniprotkb:Gatad2a(gene name)|psi-mi:Gatad2a(display_short)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000036180(gene)|ensembl:ENSMUST00000116463(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001842"(neural fold formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0012501"(programmed cell death)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0021506"(anterior neuropore closure)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR032346|interpro:IPR040386|mint:Q8CHY6|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|ensembl:ENSMUST00000212478(transcript)|refseq:XP_011240597.1|refseq:NP_001106817.1 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:Sl8kjbcfcvx+CKED3wLD9HvAEjs10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q60973 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-302297|ensembl:ENSMUSP00000033720|uniprotkb:Q3UX20|uniprotkb:A2AFJ0 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:rbbp7_mouse(display_long)|uniprotkb:Rbbp7(gene name)|psi-mi:Rbbp7(display_short)|uniprotkb:Rbap46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q60973|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-606279|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-8951664|reactome:R-MMU-8953750|ensembl:ENSMUSG00000031353(gene)|ensembl:ENSMUST00000033720(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_033057.3|dip:DIP-32856N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:+OV9hWS13A8fAypZJAXf656Z25U10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q7TSZ8 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-5691985|uniprotkb:Q80X97|uniprotkb:Q9CZ72|ensembl:ENSMUSP00000001975 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:nacc1_mouse(display_long)|uniprotkb:Nacc1(gene name)|psi-mi:Nacc1(display_short)|uniprotkb:Btbd14b(gene name synonym)|uniprotkb:Nac1(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein 14B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_080064.3|refseq:XP_006531355.1|refseq:XP_006531356.1|refseq:XP_006531357.1|dip:DIP-29930N|ensembl:ENSMUSG00000001910(gene)|ensembl:ENSMUST00000001975(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR018379|mint:Q7TSZ8 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:Mp3o/oidyfj6U+OTJwTb2WP4Q3Y10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:O88712 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-604547|ensembl:ENSMUSP00000078682|uniprotkb:Q3TAT1|uniprotkb:Q3TDL5|uniprotkb:Q3TUM5|uniprotkb:Q91WI6|uniprotkb:Q91YX3|uniprotkb:Q9QYG2 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:ctbp1_mouse(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|ensembl:ENSMUSG00000037373(gene)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|ensembl:ENSMUST00000079746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|go:"GO:0003682"(chromatin binding)|interpro:IPR029753|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR036291|go:"GO:0005737"(cytoplasm)|interpro:IPR043322|go:"GO:0006342"|mint:O88712|reactome:R-MMU-3769402|reactome:R-MMU-3899300|reactome:R-MMU-4641265|go:"GO:0008134"(transcription factor binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|refseq:NP_001185788.1|refseq:NP_001185789.1|refseq:NP_001185790.1|refseq:NP_038530.1|refseq:NP_001297464.1|dip:DIP-33907N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:l2rq9ypazCscM/WbocEKgQZcEBo10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9ER74 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-2312562|uniprotkb:Q920R5 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:sall1_mouse(display_long)|uniprotkb:Sall1(gene name)|psi-mi:Sall1(display_short)|uniprotkb:Sal3(gene name synonym)|uniprotkb:Zinc finger protein Spalt-3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 dip:DIP-54906N|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031129"(inductive cell-cell signaling)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010369"(chromocenter)|go:"GO:0016581"(NuRD complex)|go:"GO:0060173"(limb development)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072092"(ureteric bud invasion)|go:"GO:0072309"(mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000384"(negative regulation of ectoderm development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:Izbkv4nqxte6ww3HvP4XCCueQGg10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9QX96 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-5747735|uniprotkb:Q5U3X1|ensembl:ENSMUSP00000056401 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:sall2_mouse(display_long)|uniprotkb:Sall2(gene name)|psi-mi:Sall2(display_short)|uniprotkb:Sal2(gene name synonym)|uniprotkb:Spalt-like protein 2(gene name synonym)|uniprotkb:Zinc finger protein Spalt-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001231845.1|refseq:NP_056587.2|ensembl:ENSMUSG00000049532(gene)|ensembl:ENSMUST00000058326(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021915"(neural tube development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9QX96 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:YYn8vP1PeHbQAVMceGT+ZReyRfg10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q8VDP4 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-2931660|ensembl:ENSMUSP00000036924|uniprotkb:Q6PIB1|uniprotkb:Q8BWR5|uniprotkb:Q8C0F0|uniprotkb:Q8R3G6 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:ccar2_mouse(display_long)|uniprotkb:Ccar2(gene name)|psi-mi:Ccar2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000033712(gene)|ensembl:ENSMUST00000035612(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR028811|mint:Q8VDP4|reactome:R-MMU-3371453|refseq:NP_666167.3|refseq:XP_006518959.1 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:4KqmxaC2o3+yWOF9dwQ9kQ7AMqs10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9CZU3 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123099|ensembl:ENSMUSP00000022281 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:mtrex_mouse(display_long)|uniprotkb:Mtrex(gene name)|psi-mi:Mtrex(display_short)|uniprotkb:ATP-dependent helicase SKIV2L2(gene name synonym)|uniprotkb:Skiv2l2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_082427.1|ensembl:ENSMUSG00000016018(gene)|ensembl:ENSMUST00000022281(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:Q9CZU3|reactome:R-MMU-6791226|reactome:R-MMU-72163 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:EpVJGMTZaEmlGdU+O9yN0J4bwM010090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P26687 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123119|ensembl:ENSMUSP00000040089 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:twst1_mouse(display_long)|uniprotkb:Twist1(gene name)|psi-mi:Twist1(display_short)|uniprotkb:Twist(gene name synonym)|uniprotkb:M-twist(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_035788.1|dip:DIP-61633N|ensembl:ENSMUSG00000035799(gene)|ensembl:ENSMUST00000049089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001843"(neural tube closure)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032502"(developmental process)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042476"(odontogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044092"(negative regulation of molecular function)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:0060900"(embryonic camera-type eye formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061309"(cardiac neural crest cell development involved in outflow tract morphogenesis)|go:"GO:0070888"(E-box binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000276"(negative regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000780"(negative regulation of double-strand break repair)|go:"GO:2000793"(cell proliferation involved in heart valve development)|go:"GO:2000802"(positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:xTa/h67tCYqNPIgmmS2inXa8FKc10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q91YZ2 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-1216418|ensembl:ENSMUSP00000127448 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:q91yz2_mouse(display_long)|uniprotkb:Ctbp2(gene name)|psi-mi:Ctbp2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:XP_006507378.1|refseq:NP_001334552.1|ensembl:ENSMUSG00000030970(gene)|ensembl:ENSMUST00000166439(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0051287"(NAD binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:bc25+qBCXsvVf7hiGuH/+kjZjQ410090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q8R1A4 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-776274|uniprotkb:Q45V78|uniprotkb:Q5PRE6|uniprotkb:Q6PJ17|uniprotkb:Q9CSB6|uniprotkb:Q9CXM7 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:dock7_mouse(display_long)|uniprotkb:Gm430(gene name synonym)|uniprotkb:Dock7(gene name)|psi-mi:Dock7(display_short)|uniprotkb:Kiaa1771(gene name synonym)|uniprotkb:Mnlt(gene name synonym)|uniprotkb:Protein moonlight(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 interpro:IPR027357|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR043162|interpro:IPR043161|interpro:IPR026791|interpro:IPR027007|interpro:IPR035892|interpro:IPR037808|mint:Q8R1A4|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043473"(pigmentation)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|reactome:R-MMU-8875555|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-983231 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:T4W30iJF8XaTuK57c9vlJFr9gpg10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:O09106 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-301912|uniprotkb:P97476|ensembl:ENSMUSP00000099657 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:hdac1_mouse(display_long)|uniprotkb:Hdac1(gene name)|psi-mi:Hdac1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 dip:DIP-31499N|ensembl:ENSMUSG00000028800(gene)|ensembl:ENSMUST00000102597(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_032254.1|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O09106|reactome:R-MMU-1538133|reactome:R-MMU-201722|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-3769402|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8936459|reactome:R-MMU-8943724|reactome:R-MMU-9018519|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0001046"(core promoter sequence-specific DNA binding) go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:P7QV++FiMiNcabUkswbnNhGVU3410090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P70288 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-302251|uniprotkb:B2RRP3 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:hdac2_mouse(display_long)|uniprotkb:Hdac2(gene name)|psi-mi:Hdac2(display_short)|uniprotkb:Yy1bp(gene name synonym)|uniprotkb:YY1 transcription factor-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034739"("histone deacetylase activity (H4-K16 specific)")|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|refseq:NP_032255.2|dip:DIP-32854N|mint:P70288 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:bGLIDKTlyhBz40NViC8calRacZ010090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:A1L3S7 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-5668275|ensembl:ENSMUSP00000143085 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:a1l3s7_mouse(display_long)|uniprotkb:Gatad2b(gene name)|psi-mi:Gatad2b(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000042390(gene)|ensembl:ENSMUST00000197988(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:BJjSQWHfPsqJNYrmy06aaf6tYjY10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9R190 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-904134|uniprotkb:Q3TVT8|ensembl:ENSMUSP00000093959 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:mta2_mouse(display_long)|uniprotkb:Mta2(gene name)|psi-mi:Mta2(display_short)|uniprotkb:Mta1l1(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_035972.3|dip:DIP-36630N|ensembl:ENSMUSG00000071646(gene)|ensembl:ENSMUST00000096240(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006323"(DNA packaging)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:Q9R190|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:iHG+WZKTCRwTvC7LdS7OayvcEuA10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q6PDQ2 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-3043852|ensembl:ENSMUSP00000060054 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9WTM5 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-2549911|ensembl:ENSMUSP00000103400|ensembl:ENSMUSP00000147502 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:ruvb2_mouse(display_long)|uniprotkb:Ruvbl2(gene name)|psi-mi:Ruvbl2(display_short)|uniprotkb:p47 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000003868(gene)|ensembl:ENSMUST00000107771(transcript)|ensembl:ENSMUST00000211214(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051117"(ATPase binding)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9WTM5|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:NP_035434.1|refseq:XP_006540785.1|refseq:XP_006540786.1 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:tHnjngaz5qWy9sPXagFLp3TRDtA10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:P60122 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-1634999|uniprotkb:O35753|ensembl:ENSMUSP00000032165 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:ruvb1_mouse(display_long)|uniprotkb:Ruvbl1(gene name)|psi-mi:Ruvbl1(display_short)|uniprotkb:Tip49(gene name synonym)|uniprotkb:Tip49a(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:DNA helicase p50(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_062659.1|ensembl:ENSMUSG00000030079(gene)|ensembl:ENSMUST00000032165(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:P60122|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-5696394|reactome:R-MMU-606279 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:fZiQ7AurvKII0LYc+haBswAXfZ410090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q80YV3 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-2942477|uniprotkb:Q8C0Z5|uniprotkb:Q8K104 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:trrap_mouse(display_long)|uniprotkb:Trrap(gene name)|psi-mi:Trrap(display_short)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|dip:DIP-29177N|mint:Q80YV3 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:gB6vJ5mDsz4UFIbdOcUgzOlsqV810090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:O88712 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-604547|ensembl:ENSMUSP00000078682|uniprotkb:Q3TAT1|uniprotkb:Q3TDL5|uniprotkb:Q3TUM5|uniprotkb:Q91WI6|uniprotkb:Q91YX3|uniprotkb:Q9QYG2 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:ctbp1_mouse(display_long)|uniprotkb:Ctbp1(gene name)|psi-mi:Ctbp1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|ensembl:ENSMUSG00000037373(gene)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|ensembl:ENSMUST00000079746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|go:"GO:0003682"(chromatin binding)|interpro:IPR029753|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR036291|go:"GO:0005737"(cytoplasm)|interpro:IPR043322|go:"GO:0006342"|mint:O88712|reactome:R-MMU-3769402|reactome:R-MMU-3899300|reactome:R-MMU-4641265|go:"GO:0008134"(transcription factor binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|refseq:NP_001185788.1|refseq:NP_001185789.1|refseq:NP_001185790.1|refseq:NP_038530.1|refseq:NP_001297464.1|dip:DIP-33907N go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:l2rq9ypazCscM/WbocEKgQZcEBo10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q91ZW3 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-927547|uniprotkb:Q8C791|uniprotkb:Q8CA22|uniprotkb:Q8VDG1|uniprotkb:Q925M9|ensembl:ENSMUSP00000044361 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:smca5_mouse(display_long)|uniprotkb:Smarca5(gene name)|psi-mi:Smarca5(display_short)|uniprotkb:Snf2h(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_444354.2|dip:DIP-36073N|ensembl:ENSMUSG00000031715(gene)|ensembl:ENSMUST00000043359(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:Q91ZW3|reactome:R-MMU-5250924|reactome:R-MMU-5693565|reactome:R-MMU-606279 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:+HXPfdDGqKssFXooxGP7gM+u8Oc10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q9Z1J1 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-646762|uniprotkb:O70450|uniprotkb:O70573 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:tf7l1_mouse(display_long)|uniprotkb:HMG box transcription factor 3(gene name synonym)|uniprotkb:Tcf7l1(gene name)|psi-mi:Tcf7l1(display_short)|uniprotkb:Tcf3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_033358.2|dip:DIP-49605N|interpro:IPR027397|interpro:IPR028778|interpro:IPR036910|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043588"(skin development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|reactome:R-MMU-201722|reactome:R-MMU-3769402|reactome:R-MMU-4641265|reactome:R-MMU-8951430|reactome:R-MMU-4086398|reactome:R-MMU-8853884 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:l/DKng9W5qg5AQVpnfjPVIfaE+w10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q04886 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123240|ensembl:ENSMUSP00000025003 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:sox8_mouse(display_long)|uniprotkb:Sox8(gene name)|psi-mi:Sox8(display_short)|uniprotkb:Sox-8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_035577.1|ensembl:ENSMUSG00000024176(gene)|ensembl:ENSMUST00000025003(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0014032"(neural crest cell development)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0048469"(cell maturation)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060018"(astrocyte fate commitment)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060221"(retinal rod cell differentiation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061138"(morphogenesis of a branching epithelium)|go:"GO:0072034"(renal vesicle induction)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0090184"(positive regulation of kidney development)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022151|interpro:IPR031265|interpro:IPR036910 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:QxQXvlpz/8DoijNv8Uedea9EMWU10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q2TBA9 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123215|ensembl:ENSMUSP00000076403 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:q2tba9_mouse(display_long)|uniprotkb:Sox5(gene name)|psi-mi:Sox5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_001107031.2|refseq:NP_001230092.1|refseq:NP_035574.2|ensembl:ENSMUSG00000041540(gene)|ensembl:ENSMUST00000077160(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:LmaYh+wFOAfr6rdy0t3rDhW0dgA10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q91VN1 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123187|uniprotkb:Q5MDG8|uniprotkb:Q9WUQ0|ensembl:ENSMUSP00000064637|ensembl:ENSMUSP00000122579 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:znf24_mouse(display_long)|uniprotkb:Znf24(gene name)|psi-mi:Znf24(display_short)|uniprotkb:Hmcns(gene name synonym)|uniprotkb:Zfp191(gene name synonym)|uniprotkb:Hypomyelinated CNS protein(gene name synonym)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein ZF-12(gene name synonym)|uniprotkb:Zfp24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6120101|imex:IM-17312-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:XP_006526199.1|refseq:XP_006526200.1|refseq:NP_067534.2|ensembl:ENSMUSG00000051469(gene)|ensembl:ENSMUST00000066497(transcript)|ensembl:ENSMUST00000153337(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269 go:"GO:0005634"(nucleus) - - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:tkEyJw4DyBCe5XTRLcVNp3bgYjo10090 intact-crc:043248A6DBF76AA7|rigid:DVVLq4gITjux8dEQSB6gwz7KfI0 false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60I23 uniprotkb:Q6PDQ2 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-3043852|ensembl:ENSMUSP00000060054 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123564|imex:IM-17312-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N go:"GO:0005634"(nucleus) - - figure legend:Fig 1A|agonist:ethidium bromide|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 intact-crc:C77D7420A25A6424|rigid:7v0fwOLE/SFNtbi5I/m7MIgmdYA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60I23 uniprotkb:A2AJK6 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123618|imex:IM-17312-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Fig 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:7F4D14B82E2F86EE|rigid:pD5WHioEywu07AYwFm76Jx7kVAc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60I23 uniprotkb:Q9R190 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-904134|uniprotkb:Q3TVT8|ensembl:ENSMUSP00000093959 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:mta2_mouse(display_long)|uniprotkb:Mta2(gene name)|psi-mi:Mta2(display_short)|uniprotkb:Mta1l1(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123579|imex:IM-17312-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:NP_035972.3|dip:DIP-36630N|ensembl:ENSMUSG00000071646(gene)|ensembl:ENSMUST00000096240(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006323"(DNA packaging)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:Q9R190|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724 go:"GO:0005634"(nucleus) - - figure legend:Fig 1B, 1D.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:iHG+WZKTCRwTvC7LdS7OayvcEuA10090 intact-crc:D810AC3B8F8C7703|rigid:nOa+Ol8+VdxrWSujun8U0s0AEdc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60I23 uniprotkb:A2AJK6 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123579|imex:IM-17312-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Fig 1B, 1D.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:D810AC3B8F8C7703|rigid:nOa+Ol8+VdxrWSujun8U0s0AEdc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60I23 ensembl:ENSMUSG00000048001 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123808 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:hes5_mouse_gene(display_short)|psi-mi:ENSMUSG00000048001(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6125667|imex:IM-17312-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 - go:"GO:0005634"(nucleus) - - figure legend:Fig S5B|comment:Sox2 and Chd7 genomic co-localization are shown.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 - intact-crc:FC74C507114A686D false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000048001 uniprotkb:A2AJK6 intact:EBI-6123808 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:hes5_mouse_gene(display_short)|psi-mi:ENSMUSG00000048001(display_long) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6125691|imex:IM-17312-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Fig S5B|comment:Sox2 and Chd7 genomic co-localization are shown.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:571A3D8285D31F3F false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q60I23 ensembl:ENSMUSG00000001521 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123812 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:tulp3_mouse_gene(display_short)|psi-mi:ENSMUSG00000001521(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6125656|imex:IM-17312-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 - go:"GO:0005634"(nucleus) - - figure legend:Fig S5A|comment:Sox2 and Chd7 genomic co-localization are shown.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 - intact-crc:CC50B0725E9A2662 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000048402 uniprotkb:A2AJK6 intact:EBI-6123764 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:gli2_mouse_gene(display_short)|psi-mi:ENSMUSG00000048402(display_long) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123752|imex:IM-17312-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Fig 2H|comment:Sox2 and Chd7 genomic co-localization are shown throughout the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:3FA38C2AAF7282A3 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000027276 uniprotkb:A2AJK6 intact:EBI-6123762 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:jag1_mouse_gene(display_short)|psi-mi:ENSMUSG00000027276(display_long) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123766|imex:IM-17312-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Fig 2I|comment:Sox2 and Chd7 genomic co-localization are shown throughout the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:1B0D73D3310AACE7 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q60I23 ensembl:ENSMUSG00000048402 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123764 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:gli2_mouse_gene(display_short)|psi-mi:ENSMUSG00000048402(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123757|imex:IM-17312-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 - go:"GO:0005634"(nucleus) - - figure legend:Fig 2H|comment:Sox2 and Chd7 genomic co-localization are shown throughout the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 - intact-crc:4E9A3F09BDD98637 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000001521 uniprotkb:A2AJK6 intact:EBI-6123812 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:tulp3_mouse_gene(display_short)|psi-mi:ENSMUSG00000001521(display_long) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6125635|imex:IM-17312-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Fig S5A|comment:Sox2 and Chd7 genomic co-localization are shown.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:B869AAB5A664EB9A false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q60I23 ensembl:ENSMUSG00000027276 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123762 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:jag1_mouse_gene(display_short)|psi-mi:ENSMUSG00000027276(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123771|imex:IM-17312-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 - go:"GO:0005634"(nucleus) - - figure legend:Fig 2I|comment:Sox2 and Chd7 genomic co-localization are shown throughout the gene.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 - intact-crc:41E1472828B940C7 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A2AJK6 uniprotkb:Q60I23 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-6120118|ensembl:ENSMUSP00000096755 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:"MI:0096"(pull down) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123632|imex:IM-17312-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0005634"(nucleus) - - figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/04 2014/10/16 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 intact-crc:FCFCE7C8F4CE5D29|rigid:pD5WHioEywu07AYwFm76Jx7kVAc false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) ensembl:ENSMUSG00000001521 uniprotkb:A2AJK6 intact:EBI-6123812 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:tulp3_mouse_gene(display_short)|psi-mi:ENSMUSG00000001521(display_long) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123990|imex:IM-17312-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Fig 3C/E/S6B|comment:Knockdown of Sox2 not only reduced Sox2 binding, but also reduced binding of Chd7. Chd7 knockdown did not affect Sox2 binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:622198CBAC19949D false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000001521 uniprotkb:Q60I23 intact:EBI-6123812 intact:EBI-6120118|ensembl:ENSMUSP00000096755 psi-mi:tulp3_mouse_gene(display_short)|psi-mi:ENSMUSG00000001521(display_long) psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123851|imex:IM-17312-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0005634"(nucleus) - - figure legend:Fig 3C/D/S6B|comment:Knockdown of Sox2 not only reduced Sox2 binding, but also reduced binding of Chd7. Chd7 knockdown did not affect Sox2 binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 intact-crc:559EE6FD1490045C false binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:Q60I23 ensembl:ENSMUSG00000033585 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123804 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:necd_mouse_gene(display_short)|psi-mi:ENSMUSG00000033585(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123820|imex:IM-17312-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 - go:"GO:0005634"(nucleus) - - figure legend:Fig 3C/D/S6B|comment:Knockdown of Sox2 not only reduced Sox2 binding, but also reduced binding of Chd7. Chd7 knockdown did not affect Sox2 binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 - intact-crc:B7C48242267CEC0A false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:Q60I23 ensembl:ENSMUSG00000037169 intact:EBI-6120118|ensembl:ENSMUSP00000096755 intact:EBI-6123814 psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:mycn_mouse_gene(display_short)|psi-mi:ENSMUSG00000037169(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123858|imex:IM-17312-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 - go:"GO:0005634"(nucleus) - - figure legend:Fig 3C/D/S6B|comment:Knockdown of Sox2 not only reduced Sox2 binding, but also reduced binding of Chd7. Chd7 knockdown did not affect Sox2 binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 - intact-crc:0D14609439C19CEB false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000021318 uniprotkb:A2AJK6 intact:EBI-6123849 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:gli3_mouse_gene(display_short)|psi-mi:ENSMUSG00000021318(display_long) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123985|imex:IM-17312-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Fig 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:F970AE4B17CBBAE7 false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000021318 uniprotkb:Q60I23 intact:EBI-6123849 intact:EBI-6120118|ensembl:ENSMUSP00000096755 psi-mi:gli3_mouse_gene(display_short)|psi-mi:ENSMUSG00000021318(display_long) psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123842|imex:IM-17312-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0005634"(nucleus) - - figure legend:Fig 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 intact-crc:20DE7692E6A77023 false binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000039191 uniprotkb:Q60I23 intact:EBI-6123806 intact:EBI-6120118|ensembl:ENSMUSP00000096755 psi-mi:suh_mouse_gene(display_short)|psi-mi:ENSMUSG00000039191(display_long) psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123827|imex:IM-17312-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0005634"(nucleus) - - figure legend:Fig 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 intact-crc:E39A80DBE3437184 false binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:A2AJK6 ensembl:ENSMUSG00000039191 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-6123806 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:suh_mouse_gene(display_short)|psi-mi:ENSMUSG00000039191(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123980|imex:IM-17312-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 - go:"GO:0005634"(nucleus) - - figure legend:Fig 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 - intact-crc:BBDF68DCE9F761C9 false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000048402 uniprotkb:A2AJK6 intact:EBI-6123764 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:gli2_mouse_gene(display_short)|psi-mi:ENSMUSG00000048402(display_long) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123793|imex:IM-17312-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Fig 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:C27BE5B0BF3A2D17 false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000048402 uniprotkb:Q60I23 intact:EBI-6123764 intact:EBI-6120118|ensembl:ENSMUSP00000096755 psi-mi:gli2_mouse_gene(display_short)|psi-mi:ENSMUSG00000048402(display_long) psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123790|imex:IM-17312-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0005634"(nucleus) - - figure legend:Fig 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 intact-crc:8B820E0AE2F2A682 false binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000048001 uniprotkb:Q60I23 intact:EBI-6123808 intact:EBI-6120118|ensembl:ENSMUSP00000096755 psi-mi:hes5_mouse_gene(display_short)|psi-mi:ENSMUSG00000048001(display_long) psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123834|imex:IM-17312-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0005634"(nucleus) - - figure legend:Fig 3C/D/S6B|comment:Knockdown of Sox2 not only reduced Sox2 binding, but also reduced binding of Chd7. Chd7 knockdown did not affect Sox2 binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 intact-crc:29C34D159820CBD9 false binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000048001 uniprotkb:A2AJK6 intact:EBI-6123808 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:hes5_mouse_gene(display_short)|psi-mi:ENSMUSG00000048001(display_long) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123975|imex:IM-17312-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Fig 3C/E/S6B|comment:Knockdown of Sox2 not only reduced Sox2 binding, but also reduced binding of Chd7. Chd7 knockdown did not affect Sox2 binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:CA1BB7A921CE02B9 false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:A2AJK6 ensembl:ENSMUSG00000027276 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-6123762 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:jag1_mouse_gene(display_short)|psi-mi:ENSMUSG00000027276(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123787|imex:IM-17312-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 - go:"GO:0005634"(nucleus) - - figure legend:Fig 3C/E/S6B|comment:Knockdown of Sox2 not only reduced Sox2 binding, but also reduced binding of Chd7. Chd7 knockdown did not affect Sox2 binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 - intact-crc:23D6D7B306B468E5 false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:A2AJK6 ensembl:ENSMUSG00000033585 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 intact:EBI-6123804 psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:necd_mouse_gene(display_short)|psi-mi:ENSMUSG00000033585(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123964|imex:IM-17312-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 - go:"GO:0005634"(nucleus) - - figure legend:Fig 3C/E/S6B|comment:Knockdown of Sox2 not only reduced Sox2 binding, but also reduced binding of Chd7. Chd7 knockdown did not affect Sox2 binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 - intact-crc:BFC0623AFEA26696 false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000037169 uniprotkb:A2AJK6 intact:EBI-6123814 intact:EBI-6122905|uniprotkb:Q3TA86|uniprotkb:Q3TAG7|uniprotkb:Q3TBU4|uniprotkb:Q8C986|uniprotkb:Q8K244|ensembl:ENSMUSP00000043903|ensembl:ENSMUSP00000059079 psi-mi:mycn_mouse_gene(display_short)|psi-mi:ENSMUSG00000037169(display_long) psi-mi:chd7_mouse(display_long)|uniprotkb:Chd7(gene name)|psi-mi:Chd7(display_short)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123995|imex:IM-17312-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_006538067.1|refseq:NP_001264078.1|ensembl:ENSMUSG00000041235(gene)|ensembl:ENSMUST00000039267(transcript)|ensembl:ENSMUST00000051558(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035904"(aorta development)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048806"(genitalia development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:A2AJK6 go:"GO:0005634"(nucleus) - - figure legend:Fig 3C/E/S6B|comment:Knockdown of Sox2 not only reduced Sox2 binding, but also reduced binding of Chd7. Chd7 knockdown did not affect Sox2 binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:xGLCgish7JPQt9t6qs7dcfThPGg10090 intact-crc:EED836BD31A2BFD7 false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSMUSG00000027276 uniprotkb:Q60I23 intact:EBI-6123762 intact:EBI-6120118|ensembl:ENSMUSP00000096755 psi-mi:jag1_mouse_gene(display_short)|psi-mi:ENSMUSG00000027276(display_long) psi-mi:q60i23_mouse(display_long)|uniprotkb:Sox2(gene name)|psi-mi:Sox2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6123784|imex:IM-17312-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_035573.3|ensembl:ENSMUSG00000074637(gene)|ensembl:ENSMUST00000099151(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009611"(response to wounding)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:Q60I23 go:"GO:0005634"(nucleus) - - figure legend:Fig 3C/D/S6B|comment:Knockdown of Sox2 not only reduced Sox2 binding, but also reduced binding of Chd7. Chd7 knockdown did not affect Sox2 binding.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:wrjO9bW/1FSRTFU3393hUYE1oeI10090 intact-crc:A3C8E96FD7A5FC73 false binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:Q9P2D1 ensembl:ENSG00000134323 intact:EBI-3951683|uniprotkb:D0VBA5|uniprotkb:E9PNZ2|uniprotkb:Q05DI5|uniprotkb:Q2TAN4|uniprotkb:Q66K35|uniprotkb:Q7Z6C0|uniprotkb:Q7Z7Q2|uniprotkb:Q9NXA0|uniprotkb:Q9NXA3|intact:EBI-28967545|ensembl:ENSP00000392028 intact:EBI-6124137 psi-mi:chd7_human(display_long)|uniprotkb:CHD7(gene name)|psi-mi:CHD7(display_short)|uniprotkb:KIAA1416(gene name synonym)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:mycn_human_gene(display_short)|psi-mi:ENSG00000134323(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6124177|imex:IM-17312-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSP00000392028|ensembl:ENST00000524602|ensembl:ENSP00000437061|ensembl:ENST00000525508|ensembl:ENSP00000436027|refseq:NP_001303619.1|refseq:NP_060250.2|dip:DIP-48685N|ensembl:ENSG00000171316(gene)|ensembl:ENST00000423902(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048806"(genitalia development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|go:"GO:0060173"(limb development)|interpro:IPR038718|mint:Q9P2D1|rcsb pdb:2CKC|rcsb pdb:2V0E|rcsb pdb:2V0F - - - - figure legend:Fig 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:TwKt9rt8nB0sdxPgchCTyxEfq/k9606 - intact-crc:A79B8EADCC9B20F8 false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:Q9P2D1 ensembl:ENSG00000074047 intact:EBI-3951683|uniprotkb:D0VBA5|uniprotkb:E9PNZ2|uniprotkb:Q05DI5|uniprotkb:Q2TAN4|uniprotkb:Q66K35|uniprotkb:Q7Z6C0|uniprotkb:Q7Z7Q2|uniprotkb:Q9NXA0|uniprotkb:Q9NXA3|intact:EBI-28967545|ensembl:ENSP00000392028 intact:EBI-6124127 psi-mi:chd7_human(display_long)|uniprotkb:CHD7(gene name)|psi-mi:CHD7(display_short)|uniprotkb:KIAA1416(gene name synonym)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:gli2_human_gene(display_short)|psi-mi:ENSG00000074047(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6124171|imex:IM-17312-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSP00000392028|ensembl:ENST00000524602|ensembl:ENSP00000437061|ensembl:ENST00000525508|ensembl:ENSP00000436027|refseq:NP_001303619.1|refseq:NP_060250.2|dip:DIP-48685N|ensembl:ENSG00000171316(gene)|ensembl:ENST00000423902(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048806"(genitalia development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|go:"GO:0060173"(limb development)|interpro:IPR038718|mint:Q9P2D1|rcsb pdb:2CKC|rcsb pdb:2V0E|rcsb pdb:2V0F - - - - figure legend:Fig 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:TwKt9rt8nB0sdxPgchCTyxEfq/k9606 - intact-crc:E06F95C3E238EE31 false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:Q9P2D1 ensembl:ENSG00000101384 intact:EBI-3951683|uniprotkb:D0VBA5|uniprotkb:E9PNZ2|uniprotkb:Q05DI5|uniprotkb:Q2TAN4|uniprotkb:Q66K35|uniprotkb:Q7Z6C0|uniprotkb:Q7Z7Q2|uniprotkb:Q9NXA0|uniprotkb:Q9NXA3|intact:EBI-28967545|ensembl:ENSP00000392028 intact:EBI-6124135 psi-mi:chd7_human(display_long)|uniprotkb:CHD7(gene name)|psi-mi:CHD7(display_short)|uniprotkb:KIAA1416(gene name synonym)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:jag1_human_gene(display_short)|psi-mi:ENSG00000101384(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6124153|imex:IM-17312-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSP00000392028|ensembl:ENST00000524602|ensembl:ENSP00000437061|ensembl:ENST00000525508|ensembl:ENSP00000436027|refseq:NP_001303619.1|refseq:NP_060250.2|dip:DIP-48685N|ensembl:ENSG00000171316(gene)|ensembl:ENST00000423902(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048806"(genitalia development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|go:"GO:0060173"(limb development)|interpro:IPR038718|mint:Q9P2D1|rcsb pdb:2CKC|rcsb pdb:2V0E|rcsb pdb:2V0F - - - - figure legend:Fig 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:TwKt9rt8nB0sdxPgchCTyxEfq/k9606 - intact-crc:6B48FDDB154EF059 false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:Q9P2D1 ensembl:ENSG00000106571 intact:EBI-3951683|uniprotkb:D0VBA5|uniprotkb:E9PNZ2|uniprotkb:Q05DI5|uniprotkb:Q2TAN4|uniprotkb:Q66K35|uniprotkb:Q7Z6C0|uniprotkb:Q7Z7Q2|uniprotkb:Q9NXA0|uniprotkb:Q9NXA3|intact:EBI-28967545|ensembl:ENSP00000392028 intact:EBI-6124145 psi-mi:chd7_human(display_long)|uniprotkb:CHD7(gene name)|psi-mi:CHD7(display_short)|uniprotkb:KIAA1416(gene name synonym)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:gli3_human_gene(display_short)|psi-mi:ENSG00000106571(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6124165|imex:IM-17312-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSP00000392028|ensembl:ENST00000524602|ensembl:ENSP00000437061|ensembl:ENST00000525508|ensembl:ENSP00000436027|refseq:NP_001303619.1|refseq:NP_060250.2|dip:DIP-48685N|ensembl:ENSG00000171316(gene)|ensembl:ENST00000423902(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048806"(genitalia development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|go:"GO:0060173"(limb development)|interpro:IPR038718|mint:Q9P2D1|rcsb pdb:2CKC|rcsb pdb:2V0E|rcsb pdb:2V0F - - - - figure legend:Fig 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:TwKt9rt8nB0sdxPgchCTyxEfq/k9606 - intact-crc:A28A843F232DA60B false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSG00000101384 uniprotkb:P48431 intact:EBI-6124135 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 psi-mi:jag1_human_gene(display_short)|psi-mi:ENSG00000101384(display_long) psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6124129|imex:IM-17312-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 - - - figure legend:Fig 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 intact-crc:5399071D0620DB95 false binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:P48431 ensembl:ENSG00000074047 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-6124127 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:gli2_human_gene(display_short)|psi-mi:ENSG00000074047(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6124121|imex:IM-17312-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 - - - - figure legend:Fig 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 - intact-crc:D8BE6F05F156C5FD false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:P48431 ensembl:ENSG00000106571 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-6124145 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:gli3_human_gene(display_short)|psi-mi:ENSG00000106571(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6124147|imex:IM-17312-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 - - - - figure legend:Fig 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 - intact-crc:9A5B7EF930438DC7 false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:P48431 ensembl:ENSG00000182636 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-6124078 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:necd_human_gene(display_short)|psi-mi:ENSG00000182636(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6124076|imex:IM-17312-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 - - - - figure legend:Fig 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 - intact-crc:10743E2A4DE44292 false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) uniprotkb:Q9P2D1 ensembl:ENSG00000182636 intact:EBI-3951683|uniprotkb:D0VBA5|uniprotkb:E9PNZ2|uniprotkb:Q05DI5|uniprotkb:Q2TAN4|uniprotkb:Q66K35|uniprotkb:Q7Z6C0|uniprotkb:Q7Z7Q2|uniprotkb:Q9NXA0|uniprotkb:Q9NXA3|intact:EBI-28967545|ensembl:ENSP00000392028 intact:EBI-6124078 psi-mi:chd7_human(display_long)|uniprotkb:CHD7(gene name)|psi-mi:CHD7(display_short)|uniprotkb:KIAA1416(gene name synonym)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:necd_human_gene(display_short)|psi-mi:ENSG00000182636(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6124159|imex:IM-17312-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSP00000392028|ensembl:ENST00000524602|ensembl:ENSP00000437061|ensembl:ENST00000525508|ensembl:ENSP00000436027|refseq:NP_001303619.1|refseq:NP_060250.2|dip:DIP-48685N|ensembl:ENSG00000171316(gene)|ensembl:ENST00000423902(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048806"(genitalia development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|go:"GO:0060173"(limb development)|interpro:IPR038718|mint:Q9P2D1|rcsb pdb:2CKC|rcsb pdb:2V0E|rcsb pdb:2V0F - - - - figure legend:Fig 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 rogid:TwKt9rt8nB0sdxPgchCTyxEfq/k9606 - intact-crc:46B897E7BD5A206E false - binding-associated region:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) ensembl:ENSG00000134323 uniprotkb:P48431 intact:EBI-6124137 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 psi-mi:mycn_human_gene(display_short)|psi-mi:ENSG00000134323(display_long) psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Engelen et al. (2011) pubmed:21532573|imex:IM-17312 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6124139|imex:IM-17312-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 - - - figure legend:Fig 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells) - 2012/05/04 2014/10/16 - rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 intact-crc:9F4A746BDFF50B34 false binding-associated region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr)