#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
ensembl:ENSRNOG00000013397	uniprotkb:P32182	intact:EBI-8755801	intact:EBI-2893221	psi-mi:foxo1_rat_gene(display_short)|psi-mi:ENSRNOG00000013397(display_long)	psi-mi:foxa2_rat(display_long)|uniprotkb:Foxa2(gene name)|psi-mi:Foxa2(display_short)|uniprotkb:Hnf3b(gene name synonym)|uniprotkb:Tcf-3b(gene name synonym)|uniprotkb:Tcf3b(gene name synonym)|uniprotkb:Forkhead box protein A2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Chen et al. (2011)	pubmed:21385937	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1264"(NTNU)	intact:EBI-8755799	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	go:"GO:0000432"(positive regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001705"(ectoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007389"(pattern specification process)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030324"(lung development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032868"(response to insulin)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048468"(cell development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061448"(connective tissue development)|go:"GO:0061987"(negative regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2000971"(negative regulation of detection of glucose)|go:"GO:0046332"(SMAD binding)|rgd:2808|refseq:NP_036875.1|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018533|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:"Fig 3 FoxA2 could bind to FoxO1 promoters. A, FoxA2 bound directly to the FoxO1 promoter (−1219/−1006 bp, 214 bp) in RINm5F cells in a ChIP analysis. B, FoxA2 did not bind to another FoxO1 promoter (−985/−761 bp, 225 bp) in RINm5F cells in the ChIP assay."|curation depth:imex curation	taxid:10116(rat-rin_5f)|taxid:10116(Rattus norvegicus)	-	2012/06/11	2014/10/16	-	rogid:ovd6anQ/zyV/6t70zyqzZC/8Ens10116	intact-crc:A602FEB53A9D84E7	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSRNOG00000046458	uniprotkb:P32182	intact:EBI-8755807	intact:EBI-2893221	psi-mi:pdx1_rat_gene(display_short)|psi-mi:ENSRNOG00000046458(display_long)	psi-mi:foxa2_rat(display_long)|uniprotkb:Foxa2(gene name)|psi-mi:Foxa2(display_short)|uniprotkb:Hnf3b(gene name synonym)|uniprotkb:Tcf-3b(gene name synonym)|uniprotkb:Tcf3b(gene name synonym)|uniprotkb:Forkhead box protein A2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Chen et al. (2011)	pubmed:21385937	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1264"(NTNU)	intact:EBI-8755805	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	go:"GO:0000432"(positive regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001705"(ectoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007389"(pattern specification process)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030324"(lung development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032868"(response to insulin)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048468"(cell development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061448"(connective tissue development)|go:"GO:0061987"(negative regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2000971"(negative regulation of detection of glucose)|go:"GO:0046332"(SMAD binding)|rgd:2808|refseq:NP_036875.1|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018533|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:"Fig4A: The capacity of FoxA2 binding to the PDX-1 promoter was determined using ChIP-qPCR analysis in RINm5F cells treated with DEX (100 nM) at indicated times."|agonist:Dexamethasone|curation depth:imex curation	taxid:10116(rat-rin_5f)|taxid:10116(Rattus norvegicus)	-	2012/06/11	2014/10/16	-	rogid:ovd6anQ/zyV/6t70zyqzZC/8Ens10116	intact-crc:99EA1328EDD859B3	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)