#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96QF0 uniprotkb:P62491 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|ensembl:ENSP00000261890|uniprotkb:B2R4B6|uniprotkb:B4DT13 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym) psi-mi:"MI:0018"(two hybrid) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160880|imex:IM-17359-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N ensembl:ENSG00000103769(gene)|ensembl:ENST00000261890(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|refseq:NP_001193765.1|refseq:NP_004654.1|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|go:"GO:0019905"(syntaxin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030424"(axon)|dip:DIP-29138N - - - figure legend:Fig S3A.|comment:Rabin8 specifically interacts with the GTP-locked form of Rab11a.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606 intact-crc:52EEF5ECF03AFA1C|rigid:2apG51jrFr7rnLm+r2/Gb7FwV5A false sufficient binding region:264-460 mutation:70-70 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96QF0 uniprotkb:P61006 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-722293|intact:EBI-1054454|uniprotkb:P24407|intact:EBI-2798283|uniprotkb:Q6FHV5|uniprotkb:B4DEK7|ensembl:ENSP00000300935 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:rab8a_human(display_long)|uniprotkb:Oncogene c-mel(gene name synonym)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160868|imex:IM-17359-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_005361.2|dip:DIP-43703N|ensembl:ENSG00000167461(gene)|ensembl:ENST00000300935(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61006|rcsb pdb:3QBT|rcsb pdb:3TNF|rcsb pdb:4LHV|rcsb pdb:4LHW|rcsb pdb:4LHX|rcsb pdb:4LHY|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|rcsb pdb:4LHZ|rcsb pdb:4LI0|rcsb pdb:5SZI|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:6STF|rcsb pdb:6STG|rcsb pdb:6WHE|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:7BWT|rcsb pdb:7LWB|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:Fig S3A.|comment:Rabin8 specifically interacts with the GTP-locked form of Rab11a.|caution:"The stated Rab8A mutation \"T23N\" has been entered as \"T22N\" to conform to current UniProt numbering."|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9606 intact-crc:BB8BA5661C255DEA|rigid:mhFEBSdybUF3o+qmia54QfoYd+Q false sufficient binding region:1-316 mutation:22-22 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96QF0 uniprotkb:P62491 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|ensembl:ENSP00000261890|uniprotkb:B2R4B6|uniprotkb:B4DT13 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym) psi-mi:"MI:0018"(two hybrid) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6147302|imex:IM-17359-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N ensembl:ENSG00000103769(gene)|ensembl:ENST00000261890(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|refseq:NP_001193765.1|refseq:NP_004654.1|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|go:"GO:0019905"(syntaxin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030424"(axon)|dip:DIP-29138N - - - figure legend:Fig 3A, S3A.|comment:Rabin8 specifically interacts with the GTP-locked form of Rab11a.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606 intact-crc:2B7969FEDE7EFE23|rigid:2apG51jrFr7rnLm+r2/Gb7FwV5A false - mutation:70-70 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96QF0 uniprotkb:Q3TLI0 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160806|uniprotkb:Q811H4|uniprotkb:F8VQF9|ensembl:ENSMUSP00000000384 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc10_mouse(display_long)|uniprotkb:Trappc10(gene name)|psi-mi:Trappc10(display_short)|uniprotkb:Tmem1(gene name synonym)|uniprotkb:Trafficking protein particle complex subunit TMEM1(gene name synonym)|uniprotkb:Transport protein particle subunit TMEM1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160656|imex:IM-17359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_001074524.1|ensembl:ENSMUSG00000000374(gene)|ensembl:ENSMUST00000000384(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:1990071"(TRAPPII protein complex)|interpro:IPR022233|reactome:R-MMU-204005|reactome:R-MMU-8876198 go:"GO:0005813"(centrosome) - - figure legend:Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2012/06/13 2021/02/11 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:tAqRAIg1LkKTGhhF8EdSnlU2oBg10090 intact-crc:291010193100CBD9|rigid:339JccY+yQRMlMg6m0eNj3fGBY0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q9JME7 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160792|uniprotkb:A4FUI9|ensembl:ENSMUSP00000015157 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc2l_mouse(display_long)|uniprotkb:Trappc2l(gene name)|psi-mi:Trappc2l(display_short) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160656|imex:IM-17359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_067477.1|ensembl:ENSMUSG00000015013(gene)|ensembl:ENSMUST00000015157(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|interpro:IPR044760|mint:Q9JME7|reactome:R-MMU-204005|reactome:R-MMU-8876198 go:"GO:0005813"(centrosome) - - figure legend:Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2012/06/13 2021/02/11 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:k4kz7xrTd2DH+UuUlDVjO7Yv7ws10090 intact-crc:291010193100CBD9|rigid:339JccY+yQRMlMg6m0eNj3fGBY0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q5NCF2 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160777|ensembl:ENSMUSP00000099661|ensembl:ENSMUSP00000099662 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc1_mouse(display_long)|uniprotkb:Trappc1(gene name)|psi-mi:Trappc1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160656|imex:IM-17359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_001019377.1|ensembl:ENSMUSG00000049299(gene)|ensembl:ENSMUST00000102601(transcript)|ensembl:ENSMUST00000102602(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|interpro:IPR007233(Sybindin-like protein)|interpro:IPR011012(Longin-like)|rcsb pdb:2J3T|reactome:R-MMU-204005|reactome:R-MMU-6798695|reactome:R-MMU-8876198 go:"GO:0005813"(centrosome) - - figure legend:Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2012/06/13 2021/02/11 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:F3MHg2iz14r5x4TpB0ETOua1N0Q10090 intact-crc:291010193100CBD9|rigid:339JccY+yQRMlMg6m0eNj3fGBY0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q9CQP2 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-1172267|uniprotkb:Q8BP61|uniprotkb:Q9CQF5|uniprotkb:Q9D0V3|uniprotkb:Q9DCM3|ensembl:ENSMUSP00000107813|ensembl:ENSMUSP00000112195 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc2_mouse(display_long)|uniprotkb:Trappc2(gene name)|psi-mi:Trappc2(display_short)|uniprotkb:Sedl(gene name synonym)|uniprotkb:Sedlin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160656|imex:IM-17359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_079595.1|refseq:NP_079708.2|refseq:NP_001300651.1|ensembl:ENSMUSG00000079317(gene)|ensembl:ENSMUST00000112194(transcript)|ensembl:ENSMUST00000116495(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|rcsb pdb:1H3Q|rcsb pdb:2J3W|reactome:R-MMU-204005|reactome:R-MMU-8876198|go:"GO:0030008"(TRAPP complex)|refseq:XP_006533980.1|refseq:XP_006533981.1|refseq:XP_006533982.1 go:"GO:0005813"(centrosome) - - figure legend:Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2012/06/13 2021/02/11 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:GLh71F+osh+lZK15VjEPYhsPIfs10090 intact-crc:291010193100CBD9|rigid:339JccY+yQRMlMg6m0eNj3fGBY0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q9D289 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160764|ensembl:ENSMUSP00000021380 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc6b_mouse(display_long)|uniprotkb:Trappc6b(gene name)|psi-mi:Trappc6b(display_short) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160656|imex:IM-17359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_001293146.1|refseq:NP_001293147.1|refseq:NP_084333.1|ensembl:ENSMUSG00000020993(gene)|ensembl:ENSMUST00000021380(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007399"(nervous system development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR024096|interpro:IPR037992|reactome:R-MMU-204005|reactome:R-MMU-8876198 go:"GO:0005813"(centrosome) - - figure legend:Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2012/06/13 2021/02/11 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:zC35JuVZ9zxvebpK/eKfT/QnkCs10090 intact-crc:291010193100CBD9|rigid:339JccY+yQRMlMg6m0eNj3fGBY0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:O55013 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-1172223|ensembl:ENSMUSP00000030660 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc3_mouse(display_long)|uniprotkb:BET3 homolog(gene name synonym)|uniprotkb:Trappc3(gene name)|psi-mi:Trappc3(display_short)|uniprotkb:Bet3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160656|imex:IM-17359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N ensembl:ENSMUSG00000028847(gene)|ensembl:ENSMUST00000030660(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|mint:O55013|rcsb pdb:1WC8|rcsb pdb:1WC9|rcsb pdb:2J3R|rcsb pdb:2J3T|rcsb pdb:2J3W|rcsb pdb:2PWN|reactome:R-MMU-204005|reactome:R-MMU-8876198|refseq:NP_038746.1 go:"GO:0005813"(centrosome) - - figure legend:Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2012/06/13 2021/02/11 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:VoANjtqe/P6oziS0WRdNJprvMUI10090 intact-crc:291010193100CBD9|rigid:339JccY+yQRMlMg6m0eNj3fGBY0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q3UPR7 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160750|uniprotkb:E9Q2B4|ensembl:ENSMUSP00000132164 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tm102_mouse(display_long)|uniprotkb:Tmem102(gene name)|psi-mi:Tmem102(display_short) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160656|imex:IM-17359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_001028605.2|ensembl:ENSMUSG00000089876(gene)|ensembl:ENSMUST00000051025(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:1901028"(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR024806|interpro:IPR024810 go:"GO:0005813"(centrosome) - - figure legend:Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2012/06/13 2021/02/11 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:mZ1ZkMqjE5JUotiDmX9Q/RIv33810090 intact-crc:291010193100CBD9|rigid:339JccY+yQRMlMg6m0eNj3fGBY0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q3U0M1 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160720|uniprotkb:Q3UU81|uniprotkb:Q69Z79|uniprotkb:Q6NS50|uniprotkb:Q8CD01|uniprotkb:Q8CFV8|uniprotkb:Q9D8R6 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc9_mouse(display_long)|uniprotkb:Trappc9(gene name)|psi-mi:Trappc9(display_short)|uniprotkb:Kiaa1882(gene name synonym)|uniprotkb:Nibp(gene name synonym)|uniprotkb:NIK- and IKBKB-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160656|imex:IM-17359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N mint:Q3U0M1|refseq:NP_001158113.1|refseq:NP_001158114.1|refseq:NP_001158115.1|refseq:NP_083916.1|refseq:NP_850993.2|interpro:IPR013935(Transport protein Trs120)|refseq:XP_006521590.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030182"(neuron differentiation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|reactome:R-MMU-204005|reactome:R-MMU-8876198 go:"GO:0005813"(centrosome) - - figure legend:Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2012/06/13 2021/02/11 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:4o6Vzu9Mu9hWN7CZ+ifMfOffaGk10090 intact-crc:291010193100CBD9|rigid:339JccY+yQRMlMg6m0eNj3fGBY0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q9ES56 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160695|uniprotkb:Q9DB31|ensembl:ENSMUSP00000034623 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc4_mouse(display_long)|uniprotkb:Trappc4(gene name)|psi-mi:Trappc4(display_short)|uniprotkb:Sbdn(gene name synonym)|uniprotkb:Synbindin(gene name synonym)|uniprotkb:TRS23 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160656|imex:IM-17359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_068561.1|go:"GO:0030008"(TRAPP complex)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR007233(Sybindin-like protein)|interpro:IPR011012(Longin-like)|reactome:R-MMU-204005|reactome:R-MMU-8876198|ensembl:ENSMUSG00000032112(gene)|ensembl:ENSMUST00000034623(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016358"(dendrite development) go:"GO:0005813"(centrosome) - - figure legend:Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2012/06/13 2021/02/11 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:/cYIqXiEEkvVk7Lq+96Jh93kY5010090 intact-crc:291010193100CBD9|rigid:339JccY+yQRMlMg6m0eNj3fGBY0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q9CQA1 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-1172213|uniprotkb:Q8BJX6|ensembl:ENSMUSP00000036541|ensembl:ENSMUSP00000146674 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc5_mouse(display_long)|uniprotkb:Trappc5(gene name)|psi-mi:Trappc5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160656|imex:IM-17359-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N ensembl:ENSMUSG00000040236(gene)|ensembl:ENSMUST00000044857(transcript)|ensembl:ENSMUST00000207787(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:1990070"(TRAPPI protein complex)|go:"GO:1990071"(TRAPPII protein complex)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR024096|reactome:R-MMU-204005|reactome:R-MMU-8876198|interpro:IPR016696(TRAPP I complex, Trs31)|refseq:NP_079977.3 go:"GO:0005813"(centrosome) - - figure legend:Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2012/06/13 2021/02/11 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:N99aAJzTwvTmZlHHbfjjrTuCKT410090 intact-crc:291010193100CBD9|rigid:339JccY+yQRMlMg6m0eNj3fGBY0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:P62491 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|ensembl:ENSP00000261890|uniprotkb:B2R4B6|uniprotkb:B4DT13 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6160906|imex:IM-17359-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N ensembl:ENSG00000103769(gene)|ensembl:ENST00000261890(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|refseq:NP_001193765.1|refseq:NP_004654.1|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|go:"GO:0019905"(syntaxin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030424"(axon)|dip:DIP-29138N go:"GO:0005929"(cilium) - - figure legend:Fig S3C|comment:Rabin8 colocalize on Rab11 vesicles near the cilia base.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-imcd3)|taxid:10090("Mouse inner medullary collecting duct (mIMCD3) cells") - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606 intact-crc:3673ABF80BC62727|rigid:2apG51jrFr7rnLm+r2/Gb7FwV5A false tandem tag:n-n red fluorescent protein tag:?-?|mutation:70-70 - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q96QF0 uniprotkb:P48553 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160572|uniprotkb:Q86SI7|uniprotkb:Q3MIR2|uniprotkb:Q9UMD4|uniprotkb:Q9Y4L3|ensembl:ENSP00000291574 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc10_human(display_long)|uniprotkb:TRAPPC10(gene name)|psi-mi:TRAPPC10(display_short)|uniprotkb:EHOC1(gene name synonym)|uniprotkb:TMEM1(gene name synonym)|uniprotkb:Epilepsy holoprosencephaly candidate 1 protein(gene name synonym)|uniprotkb:Protein GT334(gene name synonym)|uniprotkb:Trafficking protein particle complex subunit TMEM1(gene name synonym)|uniprotkb:Transport protein particle subunit TMEM1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160950|imex:IM-17359-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:XP_016855323.1|refseq:NP_003265.3|dip:DIP-48281N|ensembl:ENSG00000160218(gene)|ensembl:ENST00000291574(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:1990071"(TRAPPII protein complex)|interpro:IPR022233|reactome:R-HSA-204005|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig S4A, S4F, S4I.|comment:Rabin8-TRAPPII complex binding is not affected by the presence or absence of serum, and does not require Rab11.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:VUosZh02L+11PPUoR+v8GHPPFZI9606 intact-crc:739D5EAC3337C659|rigid:rTIJCloPHH6h5PUYy/0vYlFm8Wc false tandem tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QF0 uniprotkb:Q9Y296 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-722888|uniprotkb:B4DME1|uniprotkb:A8K3A5|intact:EBI-28967645|ensembl:ENSP00000436005|ensembl:ENSP00000487467 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc4_human(display_long)|uniprotkb:Synbindin(gene name synonym)|uniprotkb:TRS23 homolog(gene name synonym)|uniprotkb:Hematopoietic stem/progenitor cell protein 172(gene name synonym)|uniprotkb:TRAPPC4(gene name)|psi-mi:TRAPPC4(display_short)|uniprotkb:SBDN(gene name synonym)|uniprotkb:CGI-104(orf name)|uniprotkb:HSPC172(orf name)|uniprotkb:PTD009(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160950|imex:IM-17359-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N ensembl:ENSP00000487467|ensembl:ENST00000629713|ensembl:ENSP00000486496|refseq:NP_057230.1|ensembl:ENST00000434101|ensembl:ENSP00000405033|ensembl:ENSP00000436005|refseq:NP_001305415.1|refseq:NP_001305417.1|refseq:NP_001305418.1|refseq:NP_001305419.1|refseq:NP_001305421.1|refseq:NP_001305423.1|dip:DIP-37871N|ensembl:ENSG00000196655(gene)|ensembl:ENSG00000280495(gene)|ensembl:ENST00000533632(transcript)|ensembl:ENST00000629243(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016358"(dendrite development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR007233(Sybindin-like protein)|interpro:IPR011012(Longin-like)|rcsb pdb:2J3T|rcsb pdb:2JSN|rcsb pdb:2ZMV|reactome:R-HSA-204005|reactome:R-HSA-3000170|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig S4A, S4F, S4I.|comment:Rabin8-TRAPPII complex binding is not affected by the presence or absence of serum, and does not require Rab11.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:9Dqiz8Vo+JYaAoNESIFFuhf2yc09606 intact-crc:739D5EAC3337C659|rigid:rTIJCloPHH6h5PUYy/0vYlFm8Wc false tandem tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QF0 uniprotkb:P0DI81 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-5663373|uniprotkb:O14582|uniprotkb:A6NEG0|uniprotkb:Q9HD16|ensembl:ENSP00000352708|ensembl:ENSP00000369953|ensembl:ENSP00000392495|ensembl:ENSP00000428900|ensembl:ENSP00000508155 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc2a_human(display_long)|uniprotkb:SEDL(gene name synonym)|uniprotkb:Sedlin(gene name synonym)|uniprotkb:TRAPPC2(gene name)|psi-mi:TRAPPC2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160950|imex:IM-17359-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:XP_011543867.1|refseq:XP_011543868.1|refseq:NP_001011658.1|refseq:NP_001122307.2|refseq:NP_055378.1|ensembl:ENSG00000196459(gene)|ensembl:ENST00000359680(transcript)|ensembl:ENST00000380579(transcript)|ensembl:ENST00000458511(transcript)|ensembl:ENST00000518847(transcript)|ensembl:ENST00000683569(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig S4A, S4F, S4I.|comment:Rabin8-TRAPPII complex binding is not affected by the presence or absence of serum, and does not require Rab11.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:9EuAomPvI2WFJ43aV3V15XuHjTE9606 intact-crc:739D5EAC3337C659|rigid:rTIJCloPHH6h5PUYy/0vYlFm8Wc false tandem tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96Q05 uniprotkb:Q96QF0 intact:EBI-6160596|uniprotkb:Q4VTT3|uniprotkb:Q658K7|uniprotkb:Q6P149|uniprotkb:Q6ZQT3|uniprotkb:Q7L5C4|uniprotkb:Q86Y21|uniprotkb:Q96SL2|uniprotkb:Q9BQA2|ensembl:ENSP00000405060|ensembl:ENSP00000498020 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 psi-mi:tppc9_human(display_long)|uniprotkb:TRAPPC9(gene name)|psi-mi:TRAPPC9(display_short)|uniprotkb:KIAA1882(gene name synonym)|uniprotkb:NIBP(gene name synonym)|uniprotkb:NIK- and IKBKB-binding protein(gene name synonym)|uniprotkb:Tularik gene 1 protein(gene name synonym)|uniprotkb:T1(orf name) psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6160842|imex:IM-17359-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308575.1|refseq:NP_001153844.1|refseq:NP_113654.4|ensembl:ENSG00000167632(gene)|ensembl:ENST00000438773(transcript)|ensembl:ENST00000648948(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030182"(neuron differentiation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR013935(Transport protein Trs120)|mint:Q96Q05|reactome:R-HSA-204005|reactome:R-HSA-8876198 refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N go:"GO:0005813"(centrosome) - - figure legend:Fig 4B,S4D.|comment:TRAPPC9 accumulated at the centrosome/centrosomal vesicles with GFP-Rabin8 after serum withdrawal.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2012/06/13 2014/10/16 rogid:LmmBavWplLRKY/Q932T4UijaHRs9606 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 intact-crc:0B534C31E400DACE|rigid:ImBBHiAuLpJvGgc7Ca6kFkSiB0w false - green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q96QF0 uniprotkb:P08107 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160821|imex:IM-17359-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|comment:only proteins unambiguously identified in Fig 4A have been entered.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:NFv4uj12xAWIr+OltarRlLDPr949606 intact-crc:D93EE8DF1AB1F0B1|rigid:SFqDs6QTFbKUpwPazlTQBEDXEhI false tandem tag:n-n|sufficient binding region:1-142 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q86SZ2 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160531|uniprotkb:B3KPS2|uniprotkb:Q5JPD6|uniprotkb:Q86U35|uniprotkb:Q86X35|ensembl:ENSP00000330289 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc6b_human(display_long)|uniprotkb:TRAPPC6B(gene name)|psi-mi:TRAPPC6B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160821|imex:IM-17359-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_001073005.1|refseq:NP_803235.1|dip:DIP-47626N|ensembl:ENSG00000182400(gene)|ensembl:ENST00000330149(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007399"(nervous system development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR024096|interpro:IPR037992|mint:Q86SZ2|rcsb pdb:2BJN|rcsb pdb:2CFH|rcsb pdb:3KXC|reactome:R-HSA-204005|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|comment:only proteins unambiguously identified in Fig 4A have been entered.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:uKQpJ/uSsQpZpbdQ3diIH1XjFXM9606 intact-crc:D93EE8DF1AB1F0B1|rigid:SFqDs6QTFbKUpwPazlTQBEDXEhI false tandem tag:n-n|sufficient binding region:1-142 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q96Q05 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160596|uniprotkb:Q4VTT3|uniprotkb:Q658K7|uniprotkb:Q6P149|uniprotkb:Q6ZQT3|uniprotkb:Q7L5C4|uniprotkb:Q86Y21|uniprotkb:Q96SL2|uniprotkb:Q9BQA2|ensembl:ENSP00000405060|ensembl:ENSP00000498020 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc9_human(display_long)|uniprotkb:TRAPPC9(gene name)|psi-mi:TRAPPC9(display_short)|uniprotkb:KIAA1882(gene name synonym)|uniprotkb:NIBP(gene name synonym)|uniprotkb:NIK- and IKBKB-binding protein(gene name synonym)|uniprotkb:Tularik gene 1 protein(gene name synonym)|uniprotkb:T1(orf name) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160821|imex:IM-17359-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_001308575.1|refseq:NP_001153844.1|refseq:NP_113654.4|ensembl:ENSG00000167632(gene)|ensembl:ENST00000438773(transcript)|ensembl:ENST00000648948(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030182"(neuron differentiation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR013935(Transport protein Trs120)|mint:Q96Q05|reactome:R-HSA-204005|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|comment:only proteins unambiguously identified in Fig 4A have been entered.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:LmmBavWplLRKY/Q932T4UijaHRs9606 intact-crc:D93EE8DF1AB1F0B1|rigid:SFqDs6QTFbKUpwPazlTQBEDXEhI false tandem tag:n-n|sufficient binding region:1-142 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:P48553 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160572|uniprotkb:Q86SI7|uniprotkb:Q3MIR2|uniprotkb:Q9UMD4|uniprotkb:Q9Y4L3|ensembl:ENSP00000291574 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc10_human(display_long)|uniprotkb:TRAPPC10(gene name)|psi-mi:TRAPPC10(display_short)|uniprotkb:EHOC1(gene name synonym)|uniprotkb:TMEM1(gene name synonym)|uniprotkb:Epilepsy holoprosencephaly candidate 1 protein(gene name synonym)|uniprotkb:Protein GT334(gene name synonym)|uniprotkb:Trafficking protein particle complex subunit TMEM1(gene name synonym)|uniprotkb:Transport protein particle subunit TMEM1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160821|imex:IM-17359-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:XP_016855323.1|refseq:NP_003265.3|dip:DIP-48281N|ensembl:ENSG00000160218(gene)|ensembl:ENST00000291574(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:1990071"(TRAPPII protein complex)|interpro:IPR022233|reactome:R-HSA-204005|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|comment:only proteins unambiguously identified in Fig 4A have been entered.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:VUosZh02L+11PPUoR+v8GHPPFZI9606 intact-crc:D93EE8DF1AB1F0B1|rigid:SFqDs6QTFbKUpwPazlTQBEDXEhI false tandem tag:n-n|sufficient binding region:1-142 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:P08107 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:NFv4uj12xAWIr+OltarRlLDPr949606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q8N9M5 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-1050459|uniprotkb:D3DTP8|ensembl:ENSP00000315387|ensembl:ENSP00000379815|ensembl:ENSP00000491063|ensembl:ENSP00000491290 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tm102_human(display_long)|uniprotkb:TMEM102(gene name)|psi-mi:TMEM102(display_short)|uniprotkb:Common beta-chain associated protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_848613.1|refseq:NP_001307373.1|ensembl:ENSG00000181284(gene)|ensembl:ENSG00000284228(gene)|ensembl:ENST00000323206(transcript)|ensembl:ENST00000396568(transcript)|ensembl:ENST00000638427(transcript)|ensembl:ENST00000639387(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:1901028"(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR024806|interpro:IPR024810 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:nc0s409ifhQpciPWtxvI5ZIhMdA9606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q9UL33 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-747601|uniprotkb:Q6ZTA7|uniprotkb:Q9NZZ4|uniprotkb:B2R4M9|ensembl:ENSP00000301021 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc2l_human(display_long)|uniprotkb:TRAPPC2L(gene name)|psi-mi:TRAPPC2L(display_short)|uniprotkb:HSPC126(orf name) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_057293.1|refseq:NP_001305453.1|refseq:NP_001305454.1|refseq:NP_001305455.1|refseq:NP_001305456.1|refseq:NP_001305457.1|refseq:NP_001305458.1|refseq:NP_001305459.1|refseq:NP_001305461.1|ensembl:ENSG00000167515(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|interpro:IPR044760|reactome:R-HSA-204005|reactome:R-HSA-8876198|ensembl:ENST00000301021(transcript) go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:NTGwYJgRjRmSBfFJnmAOc1I93+89606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:P48553 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160572|uniprotkb:Q86SI7|uniprotkb:Q3MIR2|uniprotkb:Q9UMD4|uniprotkb:Q9Y4L3|ensembl:ENSP00000291574 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc10_human(display_long)|uniprotkb:TRAPPC10(gene name)|psi-mi:TRAPPC10(display_short)|uniprotkb:EHOC1(gene name synonym)|uniprotkb:TMEM1(gene name synonym)|uniprotkb:Epilepsy holoprosencephaly candidate 1 protein(gene name synonym)|uniprotkb:Protein GT334(gene name synonym)|uniprotkb:Trafficking protein particle complex subunit TMEM1(gene name synonym)|uniprotkb:Transport protein particle subunit TMEM1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:XP_016855323.1|refseq:NP_003265.3|dip:DIP-48281N|ensembl:ENSG00000160218(gene)|ensembl:ENST00000291574(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:1990071"(TRAPPII protein complex)|interpro:IPR022233|reactome:R-HSA-204005|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:VUosZh02L+11PPUoR+v8GHPPFZI9606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q9Y5R8 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160554|uniprotkb:D3DTR0|ensembl:ENSP00000441130|ensembl:ENSP00000302783 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc1_human(display_long)|uniprotkb:TRAPPC1(gene name)|psi-mi:TRAPPC1(display_short)|uniprotkb:BET5(gene name synonym)|uniprotkb:MUM2(gene name synonym)|uniprotkb:BET5 homolog(gene name synonym)|uniprotkb:Multiple myeloma protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_001160093.1|refseq:NP_067033.1|dip:DIP-48285N|ensembl:ENSG00000170043(gene)|ensembl:ENST00000303731(transcript)|ensembl:ENST00000540486(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0035578"(azurophil granule lumen)|interpro:IPR007233(Sybindin-like protein)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-6798695|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:GBffndm51mtFULiV5SWwmxv+Bp89606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:P0DI81 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-5663373|uniprotkb:O14582|uniprotkb:A6NEG0|uniprotkb:Q9HD16|ensembl:ENSP00000352708|ensembl:ENSP00000369953|ensembl:ENSP00000392495|ensembl:ENSP00000428900|ensembl:ENSP00000508155 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc2a_human(display_long)|uniprotkb:SEDL(gene name synonym)|uniprotkb:Sedlin(gene name synonym)|uniprotkb:TRAPPC2(gene name)|psi-mi:TRAPPC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:XP_011543867.1|refseq:XP_011543868.1|refseq:NP_001011658.1|refseq:NP_001122307.2|refseq:NP_055378.1|ensembl:ENSG00000196459(gene)|ensembl:ENST00000359680(transcript)|ensembl:ENST00000380579(transcript)|ensembl:ENST00000458511(transcript)|ensembl:ENST00000518847(transcript)|ensembl:ENST00000683569(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:9EuAomPvI2WFJ43aV3V15XuHjTE9606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:O43617 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-743566|uniprotkb:B2RDN2|uniprotkb:D3DPS2|uniprotkb:A6NDN0|ensembl:ENSP00000362261 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc3_human(display_long)|uniprotkb:BET3 homolog(gene name synonym)|uniprotkb:TRAPPC3(gene name)|psi-mi:TRAPPC3(display_short)|uniprotkb:BET3(gene name synonym)|uniprotkb:CDABP0066(orf name) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_055223.1|refseq:NP_001257823.1|refseq:NP_001257824.1|refseq:NP_001257825.1|refseq:NP_001257826.1|ensembl:ENSG00000054116(gene)|ensembl:ENST00000373166(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|mint:O43617|rcsb pdb:1SZ7|rcsb pdb:2C0J|rcsb pdb:2CFH|rcsb pdb:3KXC|reactome:R-HSA-204005|reactome:R-HSA-8876198|dip:DIP-47627N go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:YEQWfs0KIBIDkvJ+2Xtz8afsDCc9606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q86SZ2 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160531|uniprotkb:B3KPS2|uniprotkb:Q5JPD6|uniprotkb:Q86U35|uniprotkb:Q86X35|ensembl:ENSP00000330289 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc6b_human(display_long)|uniprotkb:TRAPPC6B(gene name)|psi-mi:TRAPPC6B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_001073005.1|refseq:NP_803235.1|dip:DIP-47626N|ensembl:ENSG00000182400(gene)|ensembl:ENST00000330149(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007399"(nervous system development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR024096|interpro:IPR037992|mint:Q86SZ2|rcsb pdb:2BJN|rcsb pdb:2CFH|rcsb pdb:3KXC|reactome:R-HSA-204005|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:uKQpJ/uSsQpZpbdQ3diIH1XjFXM9606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q9Y296 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-722888|uniprotkb:B4DME1|uniprotkb:A8K3A5|intact:EBI-28967645|ensembl:ENSP00000436005|ensembl:ENSP00000487467 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc4_human(display_long)|uniprotkb:Synbindin(gene name synonym)|uniprotkb:TRS23 homolog(gene name synonym)|uniprotkb:Hematopoietic stem/progenitor cell protein 172(gene name synonym)|uniprotkb:TRAPPC4(gene name)|psi-mi:TRAPPC4(display_short)|uniprotkb:SBDN(gene name synonym)|uniprotkb:CGI-104(orf name)|uniprotkb:HSPC172(orf name)|uniprotkb:PTD009(orf name) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N ensembl:ENSP00000487467|ensembl:ENST00000629713|ensembl:ENSP00000486496|refseq:NP_057230.1|ensembl:ENST00000434101|ensembl:ENSP00000405033|ensembl:ENSP00000436005|refseq:NP_001305415.1|refseq:NP_001305417.1|refseq:NP_001305418.1|refseq:NP_001305419.1|refseq:NP_001305421.1|refseq:NP_001305423.1|dip:DIP-37871N|ensembl:ENSG00000196655(gene)|ensembl:ENSG00000280495(gene)|ensembl:ENST00000533632(transcript)|ensembl:ENST00000629243(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016358"(dendrite development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR007233(Sybindin-like protein)|interpro:IPR011012(Longin-like)|rcsb pdb:2J3T|rcsb pdb:2JSN|rcsb pdb:2ZMV|reactome:R-HSA-204005|reactome:R-HSA-3000170|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:9Dqiz8Vo+JYaAoNESIFFuhf2yc09606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q96Q05 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160596|uniprotkb:Q4VTT3|uniprotkb:Q658K7|uniprotkb:Q6P149|uniprotkb:Q6ZQT3|uniprotkb:Q7L5C4|uniprotkb:Q86Y21|uniprotkb:Q96SL2|uniprotkb:Q9BQA2|ensembl:ENSP00000405060|ensembl:ENSP00000498020 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc9_human(display_long)|uniprotkb:TRAPPC9(gene name)|psi-mi:TRAPPC9(display_short)|uniprotkb:KIAA1882(gene name synonym)|uniprotkb:NIBP(gene name synonym)|uniprotkb:NIK- and IKBKB-binding protein(gene name synonym)|uniprotkb:Tularik gene 1 protein(gene name synonym)|uniprotkb:T1(orf name) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_001308575.1|refseq:NP_001153844.1|refseq:NP_113654.4|ensembl:ENSG00000167632(gene)|ensembl:ENST00000438773(transcript)|ensembl:ENST00000648948(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030182"(neuron differentiation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR013935(Transport protein Trs120)|mint:Q96Q05|reactome:R-HSA-204005|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:LmmBavWplLRKY/Q932T4UijaHRs9606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:Q8IUR0 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-3246160|ensembl:ENSP00000316990|ensembl:ENSP00000399025|ensembl:ENSP00000470262|uniprotkb:A8K7I6 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc5_human(display_long)|uniprotkb:TRAPPC5(gene name)|psi-mi:TRAPPC5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N ensembl:ENSG00000181029(gene)|ensembl:ENST00000317378(transcript)|ensembl:ENST00000596148(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:1990070"(TRAPPI protein complex)|go:"GO:1990071"(TRAPPII protein complex)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016696(TRAPP I complex, Trs31)|interpro:IPR024096|reactome:R-HSA-204005|reactome:R-HSA-8876198|ensembl:ENST00000426877(transcript)|refseq:NP_001035926.1|refseq:NP_001035927.1|refseq:NP_777554.1 go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:mojNHWAAx2Vj20UWUjm0UJsHxnQ9606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:O75865 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-743573|uniprotkb:Q9BQ45|uniprotkb:Q9P092|uniprotkb:K7ERB1|uniprotkb:K7ERQ4|ensembl:ENSP00000468612 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc6a_human(display_long)|uniprotkb:TRAPPC6A(gene name)|psi-mi:TRAPPC6A(display_short)|uniprotkb:HSPC289(orf name) psi-mi:"MI:0676"(tandem affinity purification) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160492|imex:IM-17359-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_077013.1|refseq:NP_001257821.1|refseq:NP_001257822.1|refseq:NP_001257820.1|ensembl:ENSG00000007255(gene)|ensembl:ENST00000585934(transcript)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR037992|mint:O75865|rcsb pdb:2C0J|rcsb pdb:2J3T|reactome:R-HSA-204005|reactome:R-HSA-8876198|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:1903232"(melanosome assembly)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR024096|dip:DIP-37869N go:"GO:0005813"(centrosome) - - figure legend:Fig 4A, Table S1.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:fj7bq0NxA91fevb0Iu/0+Hx05Tk9606 intact-crc:ABD6E545F438FB93|rigid:4Fc1lasuBOzjtChv1SFOmdy9b+g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QF0 uniprotkb:P48553 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160572|uniprotkb:Q86SI7|uniprotkb:Q3MIR2|uniprotkb:Q9UMD4|uniprotkb:Q9Y4L3|ensembl:ENSP00000291574 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc10_human(display_long)|uniprotkb:TRAPPC10(gene name)|psi-mi:TRAPPC10(display_short)|uniprotkb:EHOC1(gene name synonym)|uniprotkb:TMEM1(gene name synonym)|uniprotkb:Epilepsy holoprosencephaly candidate 1 protein(gene name synonym)|uniprotkb:Protein GT334(gene name synonym)|uniprotkb:Trafficking protein particle complex subunit TMEM1(gene name synonym)|uniprotkb:Transport protein particle subunit TMEM1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6161092|imex:IM-17359-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:XP_016855323.1|refseq:NP_003265.3|dip:DIP-48281N|ensembl:ENSG00000160218(gene)|ensembl:ENST00000291574(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:1990071"(TRAPPII protein complex)|interpro:IPR022233|reactome:R-HSA-204005|reactome:R-HSA-8876198 go:"GO:0005813"(centrosome) - - figure legend:Fig S4E|comment:TRAPPC10 and Rabin8 colocalize on vesicles after serum starvation.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:VUosZh02L+11PPUoR+v8GHPPFZI9606 intact-crc:DAFE4BFC241A5048|rigid:fDpwzA5KMcawzn4czeb1jaCx/pE false red fluorescent protein tag:?-? tandem tag:n-n - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q15907 uniprotkb:Q96QF0 intact:EBI-722234|uniprotkb:Q2YDT2|uniprotkb:Q8NI07|uniprotkb:B2R7I4|uniprotkb:D6W671|uniprotkb:A5YM50|uniprotkb:Q5U0I1|uniprotkb:Q6FHR0|uniprotkb:Q6FI42|uniprotkb:B4DMK0|ensembl:ENSP00000333547 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 psi-mi:rb11b_human(display_long)|uniprotkb:GTP-binding protein YPT3(gene name synonym)|uniprotkb:RAB11B(gene name)|psi-mi:RAB11B(display_short)|uniprotkb:YPT3(gene name synonym) psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6160467|imex:IM-17359-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004209.2|dip:DIP-50898N|ensembl:ENSG00000185236(gene)|ensembl:ENST00000328024(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019003"(GDP binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033572"(transferrin transport)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0045054"(constitutive secretory pathway)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q15907|rcsb pdb:2F9L|rcsb pdb:2F9M|rcsb pdb:4OJK|reactome:R-HSA-8854214|reactome:R-HSA-8873719 refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N go:"GO:0005813"(centrosome) - - figure legend:Fig 3B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2012/06/13 2014/10/16 rogid:+fsu7NPmd5fgoe0TE67IcISlscA9606 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 intact-crc:D85B369A6AE30A6E|rigid:9NEJ8roFyUqu/U3hcq9xT4n0gYM false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q96QF0 uniprotkb:P48553 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160572|uniprotkb:Q86SI7|uniprotkb:Q3MIR2|uniprotkb:Q9UMD4|uniprotkb:Q9Y4L3|ensembl:ENSP00000291574 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc10_human(display_long)|uniprotkb:TRAPPC10(gene name)|psi-mi:TRAPPC10(display_short)|uniprotkb:EHOC1(gene name synonym)|uniprotkb:TMEM1(gene name synonym)|uniprotkb:Epilepsy holoprosencephaly candidate 1 protein(gene name synonym)|uniprotkb:Protein GT334(gene name synonym)|uniprotkb:Trafficking protein particle complex subunit TMEM1(gene name synonym)|uniprotkb:Transport protein particle subunit TMEM1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6161044|imex:IM-17359-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:XP_016855323.1|refseq:NP_003265.3|dip:DIP-48281N|ensembl:ENSG00000160218(gene)|ensembl:ENST00000291574(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:1990071"(TRAPPII protein complex)|interpro:IPR022233|reactome:R-HSA-204005|reactome:R-HSA-8876198 - - - figure legend:Fig S4B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:VUosZh02L+11PPUoR+v8GHPPFZI9606 intact-crc:E5286F2BC09E5180|rigid:E0Aj7jDCLH3R+KHOw+LED4CUFgM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QF0 uniprotkb:P0DI81 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-5663373|uniprotkb:O14582|uniprotkb:A6NEG0|uniprotkb:Q9HD16|ensembl:ENSP00000352708|ensembl:ENSP00000369953|ensembl:ENSP00000392495|ensembl:ENSP00000428900|ensembl:ENSP00000508155 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tpc2a_human(display_long)|uniprotkb:SEDL(gene name synonym)|uniprotkb:Sedlin(gene name synonym)|uniprotkb:TRAPPC2(gene name)|psi-mi:TRAPPC2(display_short) psi-mi:"MI:0071"(molecular sieving) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6161044|imex:IM-17359-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:XP_011543867.1|refseq:XP_011543868.1|refseq:NP_001011658.1|refseq:NP_001122307.2|refseq:NP_055378.1|ensembl:ENSG00000196459(gene)|ensembl:ENST00000359680(transcript)|ensembl:ENST00000380579(transcript)|ensembl:ENST00000458511(transcript)|ensembl:ENST00000518847(transcript)|ensembl:ENST00000683569(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030008"(TRAPP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|reactome:R-HSA-204005|reactome:R-HSA-8876198 - - - figure legend:Fig S4B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:9EuAomPvI2WFJ43aV3V15XuHjTE9606 intact-crc:E5286F2BC09E5180|rigid:E0Aj7jDCLH3R+KHOw+LED4CUFgM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QF0 uniprotkb:O43617 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-743566|uniprotkb:B2RDN2|uniprotkb:D3DPS2|uniprotkb:A6NDN0|ensembl:ENSP00000362261 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc3_human(display_long)|uniprotkb:BET3 homolog(gene name synonym)|uniprotkb:TRAPPC3(gene name)|psi-mi:TRAPPC3(display_short)|uniprotkb:BET3(gene name synonym)|uniprotkb:CDABP0066(orf name) psi-mi:"MI:0071"(molecular sieving) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6161044|imex:IM-17359-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_055223.1|refseq:NP_001257823.1|refseq:NP_001257824.1|refseq:NP_001257825.1|refseq:NP_001257826.1|ensembl:ENSG00000054116(gene)|ensembl:ENST00000373166(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|mint:O43617|rcsb pdb:1SZ7|rcsb pdb:2C0J|rcsb pdb:2CFH|rcsb pdb:3KXC|reactome:R-HSA-204005|reactome:R-HSA-8876198|dip:DIP-47627N - - - figure legend:Fig S4B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:YEQWfs0KIBIDkvJ+2Xtz8afsDCc9606 intact-crc:E5286F2BC09E5180|rigid:E0Aj7jDCLH3R+KHOw+LED4CUFgM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QF0 uniprotkb:Q9Y296 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-722888|uniprotkb:B4DME1|uniprotkb:A8K3A5|intact:EBI-28967645|ensembl:ENSP00000436005|ensembl:ENSP00000487467 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc4_human(display_long)|uniprotkb:Synbindin(gene name synonym)|uniprotkb:TRS23 homolog(gene name synonym)|uniprotkb:Hematopoietic stem/progenitor cell protein 172(gene name synonym)|uniprotkb:TRAPPC4(gene name)|psi-mi:TRAPPC4(display_short)|uniprotkb:SBDN(gene name synonym)|uniprotkb:CGI-104(orf name)|uniprotkb:HSPC172(orf name)|uniprotkb:PTD009(orf name) psi-mi:"MI:0071"(molecular sieving) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6161044|imex:IM-17359-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N ensembl:ENSP00000487467|ensembl:ENST00000629713|ensembl:ENSP00000486496|refseq:NP_057230.1|ensembl:ENST00000434101|ensembl:ENSP00000405033|ensembl:ENSP00000436005|refseq:NP_001305415.1|refseq:NP_001305417.1|refseq:NP_001305418.1|refseq:NP_001305419.1|refseq:NP_001305421.1|refseq:NP_001305423.1|dip:DIP-37871N|ensembl:ENSG00000196655(gene)|ensembl:ENSG00000280495(gene)|ensembl:ENST00000533632(transcript)|ensembl:ENST00000629243(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016358"(dendrite development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR007233(Sybindin-like protein)|interpro:IPR011012(Longin-like)|rcsb pdb:2J3T|rcsb pdb:2JSN|rcsb pdb:2ZMV|reactome:R-HSA-204005|reactome:R-HSA-3000170|reactome:R-HSA-8876198 - - - figure legend:Fig S4B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:9Dqiz8Vo+JYaAoNESIFFuhf2yc09606 intact-crc:E5286F2BC09E5180|rigid:E0Aj7jDCLH3R+KHOw+LED4CUFgM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QF0 uniprotkb:Q96Q05 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-6160596|uniprotkb:Q4VTT3|uniprotkb:Q658K7|uniprotkb:Q6P149|uniprotkb:Q6ZQT3|uniprotkb:Q7L5C4|uniprotkb:Q86Y21|uniprotkb:Q96SL2|uniprotkb:Q9BQA2|ensembl:ENSP00000405060|ensembl:ENSP00000498020 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:tppc9_human(display_long)|uniprotkb:TRAPPC9(gene name)|psi-mi:TRAPPC9(display_short)|uniprotkb:KIAA1882(gene name synonym)|uniprotkb:NIBP(gene name synonym)|uniprotkb:NIK- and IKBKB-binding protein(gene name synonym)|uniprotkb:Tularik gene 1 protein(gene name synonym)|uniprotkb:T1(orf name) psi-mi:"MI:0071"(molecular sieving) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6161044|imex:IM-17359-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:NP_001308575.1|refseq:NP_001153844.1|refseq:NP_113654.4|ensembl:ENSG00000167632(gene)|ensembl:ENST00000438773(transcript)|ensembl:ENST00000648948(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030182"(neuron differentiation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR013935(Transport protein Trs120)|mint:Q96Q05|reactome:R-HSA-204005|reactome:R-HSA-8876198 - - - figure legend:Fig S4B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2012/06/13 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:LmmBavWplLRKY/Q932T4UijaHRs9606 intact-crc:E5286F2BC09E5180|rigid:E0Aj7jDCLH3R+KHOw+LED4CUFgM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P48553 uniprotkb:Q96QF0 intact:EBI-6160572|uniprotkb:Q86SI7|uniprotkb:Q3MIR2|uniprotkb:Q9UMD4|uniprotkb:Q9Y4L3|ensembl:ENSP00000291574 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 psi-mi:tpc10_human(display_long)|uniprotkb:TRAPPC10(gene name)|psi-mi:TRAPPC10(display_short)|uniprotkb:EHOC1(gene name synonym)|uniprotkb:TMEM1(gene name synonym)|uniprotkb:Epilepsy holoprosencephaly candidate 1 protein(gene name synonym)|uniprotkb:Protein GT334(gene name synonym)|uniprotkb:Trafficking protein particle complex subunit TMEM1(gene name synonym)|uniprotkb:Transport protein particle subunit TMEM1(gene name synonym) psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Westlake et al. (2011) pubmed:21273506|imex:IM-17359 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6161070|imex:IM-17359-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016855323.1|refseq:NP_003265.3|dip:DIP-48281N|ensembl:ENSG00000160218(gene)|ensembl:ENST00000291574(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:1990071"(TRAPPII protein complex)|interpro:IPR022233|reactome:R-HSA-204005|reactome:R-HSA-8876198 refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N - - - figure legend:Fig S4C|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/06/13 2014/10/16 rogid:VUosZh02L+11PPUoR+v8GHPPFZI9606 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 intact-crc:90FB886963B73832|rigid:fDpwzA5KMcawzn4czeb1jaCx/pE false - green fluorescent protein tag:?-?|sufficient binding region:1-142 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)