#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P51141	uniprotkb:Q9D0N8	intact:EBI-1538407|uniprotkb:Q60868|uniprotkb:Q3U2D3|ensembl:ENSMUSP00000030948|ensembl:ENSMUSP00000133137	intact:EBI-6136970|uniprotkb:Q497Z2|uniprotkb:Q8BRC2|ensembl:ENSMUSP00000055528	psi-mi:dvl1_mouse(display_long)|uniprotkb:Dvl1(gene name)|psi-mi:Dvl1(display_short)|uniprotkb:Dvl(gene name synonym)|uniprotkb:DSH homolog 1(gene name synonym)	psi-mi:tmm88_mouse(display_long)|uniprotkb:Tmem88(gene name)|psi-mi:Tmem88(display_short)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Lee et al. (2010)	pubmed:21044957|imex:IM-17329	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6136980|imex:IM-17329-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034221.3|refseq:NP_001289271.1|dip:DIP-38263N|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035176"(social behavior)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008340(Dishevelled-1 protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|rcsb pdb:1FSH|rcsb pdb:1MC7|rcsb pdb:2KAW|rcsb pdb:2MX6|rcsb pdb:3PZ8|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220|ensembl:ENSMUSG00000029071(gene)|ensembl:ENSMUST00000030948(transcript)|ensembl:ENSMUST00000168552(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)	refseq:NP_080191.3|ensembl:ENSMUSG00000045377(gene)|ensembl:ENSMUST00000050140(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR033354|interpro:IPR033355	-	-	-	figure legend:2a, 2b and 2c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/22	2014/10/16	rogid:m61iD63WqE333GDlyLU6Mlnq50o10090	rogid:fiG939ozePO4qNBysi0iRtrr5Ys10090	intact-crc:0544FFB41CA1C0A8|rigid:GexUoZYwl27BjZg6o0DdLUFYxaI	false	sufficient binding region:247-341|mutation:334-334|his tag:n-n|15n label:?-?	sufficient binding region:147-159	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51141	uniprotkb:Q9D0N8	intact:EBI-1538407|uniprotkb:Q60868|uniprotkb:Q3U2D3|ensembl:ENSMUSP00000030948|ensembl:ENSMUSP00000133137	intact:EBI-6136970|uniprotkb:Q497Z2|uniprotkb:Q8BRC2|ensembl:ENSMUSP00000055528	psi-mi:dvl1_mouse(display_long)|uniprotkb:Dvl1(gene name)|psi-mi:Dvl1(display_short)|uniprotkb:Dvl(gene name synonym)|uniprotkb:DSH homolog 1(gene name synonym)	psi-mi:tmm88_mouse(display_long)|uniprotkb:Tmem88(gene name)|psi-mi:Tmem88(display_short)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lee et al. (2010)	pubmed:21044957|imex:IM-17329	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6137008|imex:IM-17329-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034221.3|refseq:NP_001289271.1|dip:DIP-38263N|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035176"(social behavior)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008340(Dishevelled-1 protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|rcsb pdb:1FSH|rcsb pdb:1MC7|rcsb pdb:2KAW|rcsb pdb:2MX6|rcsb pdb:3PZ8|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220|ensembl:ENSMUSG00000029071(gene)|ensembl:ENSMUST00000030948(transcript)|ensembl:ENSMUST00000168552(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)	refseq:NP_080191.3|ensembl:ENSMUSG00000045377(gene)|ensembl:ENSMUST00000050140(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR033354|interpro:IPR033355	-	-	-	figure legend:2e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.0x10^-6 ~0.2(molar)	2012/05/22	2014/10/16	rogid:m61iD63WqE333GDlyLU6Mlnq50o10090	rogid:fiG939ozePO4qNBysi0iRtrr5Ys10090	intact-crc:3B24EFFC6086367D|rigid:GexUoZYwl27BjZg6o0DdLUFYxaI	false	sufficient binding region:247-341|mutation:334-334|his tag:n-n	sufficient binding region:147-159	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51141	intact:EBI-6137032	intact:EBI-1538407|uniprotkb:Q60868|uniprotkb:Q3U2D3|ensembl:ENSMUSP00000030948|ensembl:ENSMUSP00000133137	-	psi-mi:dvl1_mouse(display_long)|uniprotkb:Dvl1(gene name)|psi-mi:Dvl1(display_short)|uniprotkb:Dvl(gene name synonym)|uniprotkb:DSH homolog 1(gene name synonym)	psi-mi:val-trp-val(display_short)|psi-mi:EBI-6137032(display_long)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lee et al. (2010)	pubmed:21044957|imex:IM-17329	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6137057|imex:IM-17329-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	refseq:NP_034221.3|refseq:NP_001289271.1|dip:DIP-38263N|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035176"(social behavior)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008340(Dishevelled-1 protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|rcsb pdb:1FSH|rcsb pdb:1MC7|rcsb pdb:2KAW|rcsb pdb:2MX6|rcsb pdb:3PZ8|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220|ensembl:ENSMUSG00000029071(gene)|ensembl:ENSMUST00000030948(transcript)|ensembl:ENSMUST00000168552(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)	pubmed:19157887(primary-reference)	-	-	-	figure legend:2e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.9x10^-6 ~0.3(molar)	2012/05/22	2014/10/16	rogid:m61iD63WqE333GDlyLU6Mlnq50o10090	rogid:aN5BgPFV+MAHIE78nGqjtlbp/ho-2	intact-crc:25431C6DE251A4C4|rigid:u0ZXhUmZtbKzIqj60MYoG3L9sl4	false	his tag:n-n|mutation:334-334|sufficient binding region:247-341	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)