#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0AG86 uniprotkb:P10408 intact:EBI-555877|uniprotkb:P15040|uniprotkb:Q2M7S3|ensemblbacteria:AAC76633|ensemblbacteria:BAE77683 intact:EBI-543213|uniprotkb:P75642|ensemblbacteria:AAC73209|ensemblbacteria:BAB96666 psi-mi:secb_ecoli(display_long)|uniprotkb:secB(gene name)|psi-mi:secB(display_short)|uniprotkb:Chaperone SecB(gene name synonym)|uniprotkb:JW3584(locus name)|uniprotkb:b3609(locus name) psi-mi:seca_ecoli(display_long)|uniprotkb:secA(gene name)|psi-mi:secA(display_short)|uniprotkb:azi(gene name synonym)|uniprotkb:pea(gene name synonym)|uniprotkb:prlD(gene name synonym)|uniprotkb:b0098(locus name)|uniprotkb:JW0096(locus name) psi-mi:"MI:0030"(cross-linking study) Suo et al. (2011) pubmed:21037004|imex:IM-18375 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6413019|mpidb:MPIDB-INT-1509|imex:IM-18375-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418066.1|refseq:WP_000003377.1|dip:DIP-47924N|ensemblbacteria:AAC76633(transcript)|ensemblbacteria:b3609(gene)|ensemblbacteria:BAE77683(gene)|ensemblbacteria:BAE77683(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0070678"(preprotein binding)|interpro:IPR003708(Bacterial protein export chaperone SecB)|interpro:IPR035958|rcsb pdb:1QYN|rcsb pdb:5JTL|rcsb pdb:5JTM|rcsb pdb:5JTN|rcsb pdb:5JTO|rcsb pdb:5JTP|rcsb pdb:5JTQ|rcsb pdb:5JTR refseq:NP_414640.1|refseq:WP_000905789.1|ensemblbacteria:AAC73209(transcript)|ensemblbacteria:b0098(gene)|ensemblbacteria:BAB96666(gene)|ensemblbacteria:BAB96666(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008564"(protein-exporting ATPase activity)|go:"GO:0015031"(protein transport)|go:"GO:0015462"(ABC-type protein transporter activity)|go:"GO:0017038"(protein import)|go:"GO:0031522"(cell envelope Sec protein transport complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0065002"(intracellular protein transmembrane transport)|go:"GO:0070678"(preprotein binding)|interpro:IPR000185(SecA protein)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004027(SEC-C motif)|interpro:IPR011115(SecA DEAD-like)|interpro:IPR011116(SecA Wing and Scaffold)|interpro:IPR011130(SecA preprotein cross-linking region)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014018(SecA motor DEAD)|interpro:IPR020937|interpro:IPR027417|interpro:IPR036266|interpro:IPR036670|interpro:IPR044722|rcsb pdb:1TM6|rcsb pdb:2FSF|rcsb pdb:2FSG|rcsb pdb:2FSH|rcsb pdb:2FSI|rcsb pdb:2VDA|rcsb pdb:3BXZ|rcsb pdb:6GOX|dip:DIP-10840N - - - figure legend:figure 3 and 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:uTdcbJ6dUcjup4nMjtossHv/NFM83333 rogid:yulYx4jc3iGczAjpx1NdEIupGKw83333 intact-crc:9B279D47BC68F9B3|rigid:FCuGHn8/YhUGVh4o+FTOP/WQ7Jo false mutation increasing interaction strength:35-35|mutation increasing interaction strength:126-126|mutation increasing interaction strength:149-149|mutation increasing interaction strength:146-146|mutation increasing interaction strength:155-155|mutation increasing interaction strength:87-87|mutation increasing interaction strength:43-43|mutation increasing interaction strength:136-136|mutation increasing interaction strength:85-85|mutation increasing interaction strength:92-92|mutation increasing interaction strength:33-33|mutation increasing interaction strength:24-24|mutation increasing interaction strength:14-14|mutation increasing interaction strength:50-50|mutation increasing interaction strength:45-45|mutation increasing interaction strength:147-147|mutation increasing interaction strength:143-143|mutation increasing interaction strength:65-65|mutation increasing interaction strength:46-46|mutation increasing interaction strength:141-141|mutation increasing interaction strength:150-150 mutation increasing interaction strength:9-9|mutation increasing interaction strength:605-605|mutation increasing interaction strength:603-603|mutation increasing interaction strength:636-636|mutation increasing interaction strength:11-11|mutation increasing interaction strength:601-601|mutation increasing interaction strength:607-607|mutation increasing interaction strength:609-609 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10408 uniprotkb:P10408 intact:EBI-543213|uniprotkb:P75642|ensemblbacteria:AAC73209|ensemblbacteria:BAB96666 intact:EBI-543213|uniprotkb:P75642|ensemblbacteria:AAC73209|ensemblbacteria:BAB96666 psi-mi:seca_ecoli(display_long)|uniprotkb:secA(gene name)|psi-mi:secA(display_short)|uniprotkb:azi(gene name synonym)|uniprotkb:pea(gene name synonym)|uniprotkb:prlD(gene name synonym)|uniprotkb:b0098(locus name)|uniprotkb:JW0096(locus name) psi-mi:seca_ecoli(display_long)|uniprotkb:secA(gene name)|psi-mi:secA(display_short)|uniprotkb:azi(gene name synonym)|uniprotkb:pea(gene name synonym)|uniprotkb:prlD(gene name synonym)|uniprotkb:b0098(locus name)|uniprotkb:JW0096(locus name) psi-mi:"MI:0030"(cross-linking study) Suo et al. (2011) pubmed:21037004|imex:IM-18375 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6413191|mpidb:MPIDB-INT-1507|imex:IM-18375-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_414640.1|refseq:WP_000905789.1|ensemblbacteria:AAC73209(transcript)|ensemblbacteria:b0098(gene)|ensemblbacteria:BAB96666(gene)|ensemblbacteria:BAB96666(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008564"(protein-exporting ATPase activity)|go:"GO:0015031"(protein transport)|go:"GO:0015462"(ABC-type protein transporter activity)|go:"GO:0017038"(protein import)|go:"GO:0031522"(cell envelope Sec protein transport complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0065002"(intracellular protein transmembrane transport)|go:"GO:0070678"(preprotein binding)|interpro:IPR000185(SecA protein)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004027(SEC-C motif)|interpro:IPR011115(SecA DEAD-like)|interpro:IPR011116(SecA Wing and Scaffold)|interpro:IPR011130(SecA preprotein cross-linking region)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014018(SecA motor DEAD)|interpro:IPR020937|interpro:IPR027417|interpro:IPR036266|interpro:IPR036670|interpro:IPR044722|rcsb pdb:1TM6|rcsb pdb:2FSF|rcsb pdb:2FSG|rcsb pdb:2FSH|rcsb pdb:2FSI|rcsb pdb:2VDA|rcsb pdb:3BXZ|rcsb pdb:6GOX|dip:DIP-10840N refseq:NP_414640.1|refseq:WP_000905789.1|ensemblbacteria:AAC73209(transcript)|ensemblbacteria:b0098(gene)|ensemblbacteria:BAB96666(gene)|ensemblbacteria:BAB96666(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008564"(protein-exporting ATPase activity)|go:"GO:0015031"(protein transport)|go:"GO:0015462"(ABC-type protein transporter activity)|go:"GO:0017038"(protein import)|go:"GO:0031522"(cell envelope Sec protein transport complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0065002"(intracellular protein transmembrane transport)|go:"GO:0070678"(preprotein binding)|interpro:IPR000185(SecA protein)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004027(SEC-C motif)|interpro:IPR011115(SecA DEAD-like)|interpro:IPR011116(SecA Wing and Scaffold)|interpro:IPR011130(SecA preprotein cross-linking region)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014018(SecA motor DEAD)|interpro:IPR020937|interpro:IPR027417|interpro:IPR036266|interpro:IPR036670|interpro:IPR044722|rcsb pdb:1TM6|rcsb pdb:2FSF|rcsb pdb:2FSG|rcsb pdb:2FSH|rcsb pdb:2FSI|rcsb pdb:2VDA|rcsb pdb:3BXZ|rcsb pdb:6GOX|dip:DIP-10840N - - - figure legend:figure 3 and 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:yulYx4jc3iGczAjpx1NdEIupGKw83333 rogid:yulYx4jc3iGczAjpx1NdEIupGKw83333 intact-crc:B5B6F30DFF95553D|rigid:n1nxAYw9ZCt3CYi+ZLluLuZ5zeg false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0AG86 uniprotkb:P0AG86 intact:EBI-555877|uniprotkb:P15040|uniprotkb:Q2M7S3|ensemblbacteria:AAC76633|ensemblbacteria:BAE77683 intact:EBI-555877|uniprotkb:P15040|uniprotkb:Q2M7S3|ensemblbacteria:AAC76633|ensemblbacteria:BAE77683 psi-mi:secb_ecoli(display_long)|uniprotkb:secB(gene name)|psi-mi:secB(display_short)|uniprotkb:Chaperone SecB(gene name synonym)|uniprotkb:JW3584(locus name)|uniprotkb:b3609(locus name) psi-mi:secb_ecoli(display_long)|uniprotkb:secB(gene name)|psi-mi:secB(display_short)|uniprotkb:Chaperone SecB(gene name synonym)|uniprotkb:JW3584(locus name)|uniprotkb:b3609(locus name) psi-mi:"MI:0030"(cross-linking study) Suo et al. (2011) pubmed:21037004|imex:IM-18375 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6413081|mpidb:MPIDB-INT-1508|imex:IM-18375-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418066.1|refseq:WP_000003377.1|dip:DIP-47924N|ensemblbacteria:AAC76633(transcript)|ensemblbacteria:b3609(gene)|ensemblbacteria:BAE77683(gene)|ensemblbacteria:BAE77683(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0070678"(preprotein binding)|interpro:IPR003708(Bacterial protein export chaperone SecB)|interpro:IPR035958|rcsb pdb:1QYN|rcsb pdb:5JTL|rcsb pdb:5JTM|rcsb pdb:5JTN|rcsb pdb:5JTO|rcsb pdb:5JTP|rcsb pdb:5JTQ|rcsb pdb:5JTR refseq:NP_418066.1|refseq:WP_000003377.1|dip:DIP-47924N|ensemblbacteria:AAC76633(transcript)|ensemblbacteria:b3609(gene)|ensemblbacteria:BAE77683(gene)|ensemblbacteria:BAE77683(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0070678"(preprotein binding)|interpro:IPR003708(Bacterial protein export chaperone SecB)|interpro:IPR035958|rcsb pdb:1QYN|rcsb pdb:5JTL|rcsb pdb:5JTM|rcsb pdb:5JTN|rcsb pdb:5JTO|rcsb pdb:5JTP|rcsb pdb:5JTQ|rcsb pdb:5JTR - - - figure legend:figure 3 and 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:uTdcbJ6dUcjup4nMjtossHv/NFM83333 rogid:uTdcbJ6dUcjup4nMjtossHv/NFM83333 intact-crc:CAF6BDF9717B312B|rigid:oT/+8tLg81fFIGEeIAC40sbWV4c false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)