#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B ensembl:ENSRNOG00000010708 uniprotkb:P32182 intact:EBI-8753757 intact:EBI-2893221 psi-mi:gata4_rat_gene(display_short)|psi-mi:ENSRNOG00000010708(display_long) psi-mi:foxa2_rat(display_long)|uniprotkb:Foxa2(gene name)|psi-mi:Foxa2(display_short)|uniprotkb:Hnf3b(gene name synonym)|uniprotkb:Tcf-3b(gene name synonym)|uniprotkb:Tcf3b(gene name synonym)|uniprotkb:Forkhead box protein A2(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Rojas et al. (2010) pubmed:20692247 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:1264"(NTNU) intact:EBI-8755796 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - go:"GO:0000432"(positive regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001705"(ectoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007389"(pattern specification process)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030324"(lung development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032868"(response to insulin)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048468"(cell development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061448"(connective tissue development)|go:"GO:0061987"(negative regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2000971"(negative regulation of detection of glucose)|go:"GO:0046332"(SMAD binding)|rgd:2808|refseq:NP_036875.1|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018533|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390 - - - figure legend:Fig. 6C|curation depth:imex curation taxid:10116(rat-ar42j)|taxid:10116(Rattus norvegicus) - 2012/06/19 2014/10/16 - rogid:ovd6anQ/zyV/6t70zyqzZC/8Ens10116 intact-crc:76814D4A0A356CFF false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) intact:EBI-6161020 uniprotkb:P35583 ensembl:ENSMUSG00000021944 intact:EBI-2893341|uniprotkb:A2AR89|ensembl:ENSMUSP00000045918|uniprotkb:Q60602 psi-mi:gata4_g4_mouse_dna(display_short)|psi-mi:EBI-6161020(display_long) psi-mi:foxa2_mouse(display_long)|uniprotkb:Foxa2(gene name)|psi-mi:Foxa2(display_short)|uniprotkb:Hnf3b(gene name synonym)|uniprotkb:Tcf-3b(gene name synonym)|uniprotkb:Tcf3b(gene name synonym)|uniprotkb:Forkhead box protein A2(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Rojas et al. (2010) pubmed:20692247 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1264"(NTNU) intact:EBI-6161014 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000037025(gene)|ensembl:ENSMUST00000047315(transcript)|go:"GO:0000432"(positive regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001705"(ectoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007389"(pattern specification process)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021533"(cell differentiation in hindbrain)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030324"(lung development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046332"(SMAD binding)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048468"(cell development)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048665"(neuron fate specification)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061448"(connective tissue development)|go:"GO:0061987"(negative regulation of transcription from RNA polymerase II promoter by glucose)|go:"GO:0070741"(response to interleukin-6)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090009"(primitive streak formation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2000971"(negative regulation of detection of glucose)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR013638(Fork-head N-terminal)|interpro:IPR018122|interpro:IPR018533|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|refseq:NP_034576.2|refseq:NP_001277994.1 go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding) - - figure legend:Figure 6|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 - rogid:2VSxvigdQZu8WWsul9dBXiSrg6Y10090 intact-crc:48BE3F6A76D6AEDA false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)