#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99J95 uniprotkb:P11499 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-492813|uniprotkb:O89078|uniprotkb:Q3UIQ7|ensembl:ENSMUSP00000024739 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:hs90b_mouse(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 84 kDa antigen(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hsp84-1(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_032328.2|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P11499|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-399954|reactome:R-MMU-6798695|reactome:R-MMU-844456|reactome:R-MMU-8852276|reactome:R-MMU-8937144|reactome:R-MMU-8939211|reactome:R-MMU-9013418|reactome:R-MMU-9018519|ensembl:ENSMUSG00000023944(gene)|ensembl:ENSMUST00000024739(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|dip:DIP-461N - - author-confidence:0.09 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q03347 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-3863873|uniprotkb:O08598|uniprotkb:Q62049|uniprotkb:Q9ESB9|uniprotkb:Q9ET65 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:runx1_mouse(display_long)|uniprotkb:Runx1(gene name)|psi-mi:Runx1(display_short)|uniprotkb:Aml1(gene name synonym)|uniprotkb:Cbfa2(gene name synonym)|uniprotkb:Pebp2ab(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002318"(myeloid progenitor cell differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048666"(neuron development)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0071336"(regulation of hair follicle cell proliferation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903431"(positive regulation of cell maturation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000872"(positive regulation of progesterone secretion)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384|rcsb pdb:1EAN|rcsb pdb:1EAO|rcsb pdb:1EAQ|rcsb pdb:1HJB|rcsb pdb:1HJC|rcsb pdb:1IO4|rcsb pdb:2J6W|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|dip:DIP-40723N|reactome:R-MMU-549127|reactome:R-MMU-8877330|reactome:R-MMU-8931987|reactome:R-MMU-8934593|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-8939243|reactome:R-MMU-8939245|reactome:R-MMU-8939246|reactome:R-MMU-8939247|reactome:R-MMU-9018519 - - author-confidence:0.06 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:1rh6vkqvcnroruSaiTl+xBjDpms10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q7TN02 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-310097|uniprotkb:Q8BUP9|uniprotkb:Q8R1G7|uniprotkb:Q9CS67|ensembl:ENSMUSP00000058697 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med26_mouse(display_long)|uniprotkb:Med26(gene name)|psi-mi:Med26(display_short)|uniprotkb:Crsp7(gene name synonym)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_081761.2|ensembl:ENSMUSG00000045248(gene)|ensembl:ENSMUST00000058534(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:Q7TN02|reactome:R-MMU-212436 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:bpsq5FSrkhax4hdPnRTDL+YSdIA10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q8K2T8 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-642477|uniprotkb:Q3UY97|uniprotkb:Q9CS63|uniprotkb:Q9JJ99|ensembl:ENSMUSP00000003529 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:paf1_mouse(display_long)|uniprotkb:Paf1(gene name)|psi-mi:Paf1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_062331.2|ensembl:ENSMUSG00000003437(gene)|ensembl:ENSMUST00000003529(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8K2T8|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:1cFGAVgb19bf33BaPcIowpXT5qc10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9R1C7 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-645554|uniprotkb:Q61049|uniprotkb:Q8BQ76|uniprotkb:Q8BRW4|uniprotkb:Q8C2U1|ensembl:ENSMUSP00000159339 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:pr40a_mouse(display_long)|uniprotkb:Formin-binding protein 3(gene name synonym)|uniprotkb:Formin-binding protein 11(gene name synonym)|uniprotkb:Prpf40a(gene name)|psi-mi:Prpf40a(display_short)|uniprotkb:Fbp11(gene name synonym)|uniprotkb:Fnbp3(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_061255.1|ensembl:ENSMUSG00000061136(gene)|ensembl:ENSMUST00000239398(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005685"(U1 snRNP)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0016607"(nuclear speck)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002713(FF)|interpro:IPR036020|interpro:IPR036517|interpro:IPR039726|mint:Q9R1C7|reactome:R-MMU-72163 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:urpZDf+jd9lovL7obd2Y+a/lBCE10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9R1C0 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260765|ensembl:ENSMUSP00000065645 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:taf7_mouse(display_long)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:Taf2f(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:Taf7(gene name)|psi-mi:Taf7(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|ensembl:ENSMUSG00000051316(gene)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061628"(H3K27me3 modified histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|ensembl:ENSMUST00000066272(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042|refseq:NP_786964.1 - - author-confidence:0.08 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:pBWQtnnVLNxRSSmTYEiiZisOYzQ10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q925J9 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P60710 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N - - author-confidence:0.23 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:O88532 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-645485|uniprotkb:Q3TY30|uniprotkb:Q8BS85|uniprotkb:Q8CGG5|uniprotkb:Q91VZ0|uniprotkb:Q9CT34|ensembl:ENSMUSP00000118911 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:zfr_mouse(display_long)|uniprotkb:Zfr(gene name)|psi-mi:Zfr(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_035897.2|ensembl:ENSMUSG00000022201(gene)|ensembl:ENSMUST00000122941(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR006561(DZF)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043519|mint:O88532 - - author-confidence:0.27 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:ncNwFUEUk0r2XotuXm/9Tt4iB5w10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q6GTN8 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260993 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:q6gtn8_mouse(display_long)|uniprotkb:Nfe2l1(gene name)|psi-mi:Nfe2l1(display_short)|uniprotkb:Nuclear factor erythroid 2-related factor 1(gene name synonym)|uniprotkb:Nuclear factor, erythroid derived 2, like 1(gene name synonym)|uniprotkb:Transcription factor NRF1(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR029847|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|refseq:NP_001123922.1|refseq:NP_032712.2|interpro:IPR004826(Maf transcription factor) - - author-confidence:0.25 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:0EMHyCHvjsfjPZM7rrKaHF7cr6k10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:O55142 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261093|ensembl:ENSMUSP00000077857|ensembl:ENSMUSP00000110727|ensembl:ENSMUSP00000110728|ensembl:ENSMUSP00000110730|ensembl:ENSMUSP00000110731 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rl35a_mouse(display_long)|uniprotkb:Rpl35a(gene name)|psi-mi:Rpl35a(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:O55142|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|ensembl:ENSMUST00000115079(transcript)|ensembl:ENSMUSG00000060636(gene)|ensembl:ENSMUST00000078804(transcript)|ensembl:ENSMUST00000115075(transcript)|ensembl:ENSMUST00000115076(transcript)|ensembl:ENSMUST00000115078(transcript)|refseq:NP_001123956.1|refseq:NP_001123957.1|refseq:NP_067313.2 - - author-confidence:0.21 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:YMZJVqZjsqFERlOi93R8RreIBe010090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9D0E1 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-773789|uniprotkb:Q6P1B2|uniprotkb:Q99JQ0|ensembl:ENSMUSP00000120115 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:hnrpm_mouse(display_long)|uniprotkb:Hnrpm(gene name synonym)|uniprotkb:Hnrnpm(gene name)|psi-mi:Hnrnpm(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_001103383.1|refseq:NP_084080.1|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904591"(positive regulation of protein import)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:Q9D0E1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000059208(gene)|ensembl:ENSMUST00000148178(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0048306"(calcium-dependent protein binding) - - author-confidence:0.01 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:VpoWJwPx1uDzAsBxM3/TfiCMGok10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q99K74 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-5745029|uniprotkb:A3KFP0|uniprotkb:Q8R004|uniprotkb:Q9D277|uniprotkb:Q9WVF1|ensembl:ENSMUSP00000017354 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med24_mouse(display_long)|uniprotkb:Med24(gene name)|psi-mi:Med24(display_short)|uniprotkb:D11Ertd307e(gene name synonym)|uniprotkb:Thrap4(gene name synonym)|uniprotkb:Trap100(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_035999.2|ensembl:ENSMUSG00000017210(gene)|ensembl:ENSMUST00000017354(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR021429|rcsb pdb:6W1S|reactome:R-MMU-212436|refseq:XP_006533368.1 - - author-confidence:0.03 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:GSdhLyTQrKwK1ya/qhMSzAdmFBg10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q08024 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-475586|uniprotkb:Q08025|uniprotkb:Q62050|uniprotkb:Q62051|uniprotkb:Q8C282|uniprotkb:Q8CGD5|ensembl:ENSMUSP00000059382 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:pebb_mouse(display_long)|uniprotkb:Polyomavirus enhancer-binding protein 2 beta subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 subunit beta(gene name synonym)|uniprotkb:SL3/AKV core-binding factor beta subunit(gene name synonym)|uniprotkb:Cbfb(gene name)|psi-mi:Cbfb(display_short)|uniprotkb:Pebp2b(gene name synonym)|uniprotkb:Pebpb2(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000031885(gene)|ensembl:ENSMUST00000052209(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR003417(Core binding factor, beta subunit)|refseq:NP_001154928.1|refseq:NP_001154929.1|refseq:NP_001154930.1|refseq:NP_071704.3|rcsb pdb:1ILF|interpro:IPR036552|rcsb pdb:1IO4|rcsb pdb:2JHB|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|reactome:R-MMU-8877330|reactome:R-MMU-8878166|reactome:R-MMU-8931987|reactome:R-MMU-8934593|reactome:R-MMU-8936459|reactome:R-MMU-8939236|reactome:R-MMU-8939243|reactome:R-MMU-8939245|reactome:R-MMU-8939246|reactome:R-MMU-8939247|reactome:R-MMU-8941326|reactome:R-MMU-8941858|reactome:R-MMU-8951936|reactome:R-MMU-9018519 - - author-confidence:0.27 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:rLI+FjXTPj8Z/0+MNAdcOhjHpMg10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q5XJE5 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2898760|uniprotkb:E9QPK8|ensembl:ENSMUSP00000046905|uniprotkb:Q640R1 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:leo1_mouse(display_long)|uniprotkb:Leo1(gene name)|psi-mi:Leo1(display_short)|uniprotkb:Gm185(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR007149(Leo1-like protein)|reactome:R-MMU-112382|reactome:R-MMU-201722|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSMUSG00000042487(gene)|ensembl:ENSMUST00000048937(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|refseq:NP_001034611.1 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:OgXix8fD8tBcMPOSGVGv+j6XZCg10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q8JZM7 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-1216399|ensembl:ENSMUSP00000018337 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:cdc73_mouse(display_long)|uniprotkb:Cdc73(gene name)|psi-mi:Cdc73(display_short)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_666103.1|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q8JZM7|reactome:R-MMU-112382|reactome:R-MMU-201722|reactome:R-MMU-5632684|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|ensembl:ENSMUSG00000026361(gene)|ensembl:ENSMUST00000018337(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process) - - author-confidence:0.04 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q8VH51 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-644098|uniprotkb:Q5RJI0|uniprotkb:Q99KV0|ensembl:ENSMUSP00000105216 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rbm39_mouse(display_long)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Coactivator of activating protein 1 and estrogen receptors(gene name synonym)|uniprotkb:Rbm39(gene name)|psi-mi:Rbm39(display_short)|uniprotkb:Caper(gene name synonym)|uniprotkb:Rnpc2(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_573505.2|ensembl:ENSMUSG00000027620(gene)|ensembl:ENSMUST00000109587(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q8VH51|rcsb pdb:2LQ5|rcsb pdb:3S6E|rcsb pdb:4J5O|rcsb pdb:4RU2|rcsb pdb:5CXT|refseq:XP_011237629.1|refseq:NP_001278043.1|refseq:NP_001278044.1|refseq:XP_017171483.1|refseq:XP_017171494.1|refseq:XP_017171497.1|refseq:XP_011237628.1|refseq:XP_017171487.1 - - author-confidence:0.04 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:dW5PuXllczFeyQ6ask6CFrukMKk10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P08775 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2549849|ensembl:ENSMUSP00000050771|uniprotkb:Q5F298 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rpb1_mouse(display_long)|uniprotkb:Polr2a(gene name)|psi-mi:Polr2a(display_short)|uniprotkb:Rpii215(gene name synonym)|uniprotkb:Rpo2-1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000005198(gene)|ensembl:ENSMUST00000058470(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|mint:P08775|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|reactome:R-MMU-112382|refseq:NP_001277997.1|dip:DIP-46369N - - author-confidence:0.01 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:kUX/HdU6Y2VHAGjySBcOxfS08XA10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q3TFK5 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260915|ensembl:ENSMUSP00000029707|ensembl:ENSMUSP00000132699|ensembl:ENSMUSP00000141786|uniprotkb:Q9CU32|uniprotkb:Q9D3L4|uniprotkb:Q8VCN2 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:gptc4_mouse(display_long)|uniprotkb:Gpatc4(gene name synonym)|uniprotkb:Gpatch4(gene name)|psi-mi:Gpatch4(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000028069(gene)|ensembl:ENSMUST00000029707(transcript)|ensembl:ENSMUST00000166021(transcript)|ensembl:ENSMUST00000193398(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003676"(nucleic acid binding)|interpro:IPR000467(D111/G-patch)|refseq:NP_001273786.1|refseq:NP_001104279.1|refseq:NP_079939.3 - - author-confidence:0.25 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:e/cjd2phG5qB7wmOZ+LTKGdyN1w10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9CQA5 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-5745428|uniprotkb:Q3UL96|uniprotkb:Q8BVG6|ensembl:ENSMUSP00000022705 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med4_mouse(display_long)|uniprotkb:Med4(gene name)|psi-mi:Med4(display_short)|uniprotkb:Vdrip(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_080395.1|ensembl:ENSMUSG00000022109(gene)|ensembl:ENSMUST00000022705(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9CQA5|rcsb pdb:6W1S|reactome:R-MMU-212436 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:mxprXZb8/S6/jNJVDSvApugwGiQ10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9ESC8 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261083|ensembl:ENSMUSP00000051479|uniprotkb:B2RST9|uniprotkb:Q8C6W3|uniprotkb:Q8C6K4|uniprotkb:Q8CCH3 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:aff4_mouse(display_long)|uniprotkb:Alf4(gene name synonym)|uniprotkb:Aff4(gene name)|psi-mi:Aff4(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000049470(gene)|ensembl:ENSMUST00000060945(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035327"|interpro:IPR007797(AF-4 proto-oncoprotein)|interpro:IPR043639|interpro:IPR043640|mint:Q9ESC8|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955|go:"GO:0032783"(super elongation complex)|refseq:XP_011247633.1|refseq:NP_291043.1 - - author-confidence:0.05 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:/pYgaSgjBhwmauoRLYO1WIskmzU10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q99PV0 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2551815|ensembl:ENSMUSP00000018449|ensembl:ENSMUSP00000099568|uniprotkb:A5D6Q4|uniprotkb:Q7TQK2|uniprotkb:Q8BRZ5|uniprotkb:Q8K001|uniprotkb:Q5ND30|uniprotkb:Q5ND31 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:prp8_mouse(display_long)|uniprotkb:Prp8(gene name synonym)|uniprotkb:Splicing factor Prp8(gene name synonym)|uniprotkb:Prpf8(gene name)|psi-mi:Prpf8(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000020850(gene)|ensembl:ENSMUST00000018449(transcript)|ensembl:ENSMUST00000102510(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|mint:Q99PV0|reactome:R-MMU-72163|reactome:R-MMU-72165|interpro:IPR037518|refseq:NP_619600.2 - - author-confidence:0.03 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:vHccw48piO1PjsNcxDszzscPO8010090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9DBA9 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260822|uniprotkb:O35637 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:tf2h1_mouse(display_long)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Gtf2h1(gene name)|psi-mi:Gtf2h1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|refseq:NP_001278004.1|interpro:IPR035925|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|refseq:NP_032212.3|interpro:IPR027079|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075 - - author-confidence:0.03 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:kCRvc9Bheu2o11ISottCk0cgERI10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q91Y44 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260929|ensembl:ENSMUSP00000031215|uniprotkb:G3X8Z8|uniprotkb:Q59HJ4 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:brdt_mouse(display_long)|uniprotkb:Bromodomain-containing female sterile homeotic-like protein(gene name synonym)|uniprotkb:Fsrg3(gene name synonym)|uniprotkb:RING3-like protein(gene name synonym)|uniprotkb:Brdt(gene name)|psi-mi:Brdt(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000029279(gene)|ensembl:ENSMUST00000031215(transcript)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006397"(mRNA processing)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0051039"(positive regulation of transcription involved in meiotic cell cycle)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR031354|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|rcsb pdb:2WP1|rcsb pdb:2WP2|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_001073342.1|refseq:NP_473395.2|dip:DIP-48975N - - author-confidence:0.08 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:58C4boIaeO3jJDh/pGWJ6QRP1Qs10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q7TQK0 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261078|ensembl:ENSMUSP00000027587|intact:EBI-11472070|intact:EBI-11471881|uniprotkb:K4N0L9|uniprotkb:K4N2S3 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:ccnt2_mouse(display_long)|uniprotkb:Ccnt2(gene name)|psi-mi:Ccnt2(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000026349(gene)|ensembl:ENSMUST00000027587(transcript)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019085"(early viral transcription)|go:"GO:0019086"(late viral transcription)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0097322"(7SK snRNA binding)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR028862|interpro:IPR036915|interpro:IPR043198|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|interpro:IPR013763(Cyclin-related)|refseq:NP_082675.1 - - author-confidence:0.03 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:QQ2xZIPs1obqWn0VqQGXO/zdEVc10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q8CGP2 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2314816|uniprotkb:Q64477|uniprotkb:Q6P8V8|ensembl:ENSMUSP00000100047 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:h2b1p_mouse(display_long)|uniprotkb:Hist1h2bp(gene name)|psi-mi:Hist1h2bp(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_001277395.1|refseq:XP_006516753.1|refseq:NP_835509.2|ensembl:ENSMUSG00000069308(gene)|ensembl:ENSMUST00000102982(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214847|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-606279|reactome:R-MMU-69473|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8866654|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095 - - author-confidence:0.24 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:LP4hJM0PWYk+0tiApeId0a2PaFY10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q4QY64 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260770|ensembl:ENSMUSP00000017694|uniprotkb:Q3UW85|uniprotkb:Q3V306|uniprotkb:Q3V3T9|uniprotkb:Q8CGG7|uniprotkb:Q3TMG5|uniprotkb:Q5SSK4|uniprotkb:Q8BUH4 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:atad5_mouse(display_long)|uniprotkb:Chromosome fragility-associated gene 1 protein(gene name synonym)|uniprotkb:Frag1(gene name synonym)|uniprotkb:Atad5(gene name)|psi-mi:Atad5(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000017550(gene)|ensembl:ENSMUST00000017694(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045190"(isotype switching)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0090618"(DNA clamp unloading)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|refseq:NP_001025027.1 - - author-confidence:0.03 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:Zg+dBCXr7WnX0pQFMsMTgl7nMik10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P51949 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260998|ensembl:ENSMUSP00000021523|uniprotkb:Q9D8A0|uniprotkb:Q3TZP0|uniprotkb:Q14BS9|uniprotkb:Q9D8D2 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:mat1_mouse(display_long)|uniprotkb:CDK7/cyclin-H assembly factor(gene name synonym)|uniprotkb:Mat1(gene name synonym)|uniprotkb:Menage a trois(gene name synonym)|uniprotkb:RING finger protein MAT1(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Mnat1(gene name)|psi-mi:Mnat1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000021103(gene)|reactome:R-MMU-8939236|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007512"(adult heart development)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0021591"(ventricular system development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070516"(CAK-ERCC2 complex)|ensembl:ENSMUST00000021523(transcript)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR004575("Cdk-activating kinase assembly factor (MAT1)")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015877(Cdk-activating kinase assembly factor, MAT1)|interpro:IPR017907|mint:P51949|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-69202|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-69656|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|refseq:NP_032638.2 - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:ii9dY7+pAT8fjemKdEnD+ADmzKk10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9CPR4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260896 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rl17_mouse(display_long)|uniprotkb:Rpl17(gene name)|psi-mi:Rpl17(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|rcsb pdb:6SWA|mint:Q9CPR4|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394 - - author-confidence:0.25 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:1O/Lf4KUmT/kaME3XavS27J+PGs10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q61081 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2906727|ensembl:ENSMUSP00000019615|uniprotkb:Q3TGP0 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:cdc37_mouse(display_long)|uniprotkb:Cdc37(gene name)|psi-mi:Cdc37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q61081|reactome:R-MMU-1227986|reactome:R-MMU-5675482|reactome:R-MMU-8863795|reactome:R-MMU-9013418|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|reactome:R-MMU-9652282|ensembl:ENSMUSG00000019471(gene)|ensembl:ENSMUST00000019615(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|refseq:NP_058022.1 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:v5zsOwSR7TCF51iF9RkxF1cPeaU10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q99LF4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261036|ensembl:ENSMUSP00000001834|uniprotkb:Q3UDW6|uniprotkb:Q3TI25|uniprotkb:Q3TA04 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rtcb_mouse(display_long)|uniprotkb:Rtcb(gene name)|psi-mi:Rtcb(display_short)|uniprotkb:D10Wsu52e(gene name synonym)|uniprotkb:Focal adhesion-associated protein(gene name synonym)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000001783(gene)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q99LF4|ensembl:ENSMUST00000001834(transcript)|refseq:NP_663397.1 - - author-confidence:0.08 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:ISQNiLQA7DCcgBkTueMDhUHrkFQ10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q6PGF3 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260816|uniprotkb:E9QM81 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med16_mouse(display_long)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thrap5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym)|uniprotkb:Med16(gene name)|psi-mi:Med16(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:Q6PGF3|dip:DIP-48408N - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:7RYpXMMTPBtLxPGifdlY+MdwlEM10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q6P1I6 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260887|ensembl:ENSMUSP00000111381|uniprotkb:Q8BHR9|uniprotkb:Q6NZP0|uniprotkb:Q9D3B8|uniprotkb:Q6PHQ7 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:psd2_mouse(display_long)|uniprotkb:Pleckstrin homology and SEC7 domain-containing protein 2(gene name synonym)|uniprotkb:Psd2(gene name)|psi-mi:Psd2(display_short)|uniprotkb:Efa6c(gene name synonym)|uniprotkb:Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 C(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000024347(gene)|ensembl:ENSMUST00000115716(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000904(SEC7-like)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR035999|interpro:IPR041681|mint:Q6P1I6|refseq:XP_017173484.1|refseq:NP_001276531.1|refseq:NP_082983.3 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:4gER0hfTK/tOUnY+VQ8b1gRJQdY10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P07901 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-78930|ensembl:ENSMUSP00000021698|ensembl:ENSMUSP00000091921 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:hs90a_mouse(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hsp86(gene name synonym)|uniprotkb:Hsp86-1(gene name synonym)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 86 kDa antigen(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_034610.1|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07901|rcsb pdb:5H22|reactome:R-MMU-1227986|reactome:R-MMU-1474151|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-203615|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-399954|reactome:R-MMU-4420097|reactome:R-MMU-5218920|reactome:R-MMU-5620912|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8863795|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9013418|reactome:R-MMU-9018519|reactome:R-MMU-9652282|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|ensembl:ENSMUSG00000021270(gene)|ensembl:ENSMUST00000021698(transcript)|ensembl:ENSMUST00000094361(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042026"(protein refolding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|dip:DIP-30975N - - author-confidence:0.08 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:t9XAeXdXezYOtJX0wp3IY9/ZMkQ10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q3UKU1 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260828|ensembl:ENSMUSP00000001583|uniprotkb:E9QPE1 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:ell2_mouse(display_long)|uniprotkb:Ell2(gene name)|psi-mi:Ell2(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000001542(gene)|ensembl:ENSMUST00000001583(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR019464|interpro:IPR031176|interpro:IPR031179|interpro:IPR036390|interpro:IPR042065|reactome:R-MMU-6807505|refseq:NP_620403.2 - - author-confidence:0.01 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:mTpIfB0P2ioZtbHqQ6FZ64qVVTw10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P47911 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-773947|uniprotkb:Q6P5I2|uniprotkb:Q925C3|ensembl:ENSMUSP00000031617 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rl6_mouse(display_long)|uniprotkb:TAX-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Rpl6(gene name)|psi-mi:Rpl6(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_035420.2|refseq:XP_006530290.1|ensembl:ENSMUSG00000029614(gene)|ensembl:ENSMUST00000031617(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:P47911|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 - - author-confidence:0.25 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:rm/g3X/3zoauNoUW6K4M43n8e4810090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q6ZWV3 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261064|ensembl:ENSMUSP00000008826|ensembl:ENSMUSP00000082055|ensembl:ENSMUSP00000125806|uniprotkb:P45634|uniprotkb:Q5M9K8|uniprotkb:Q569M8 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rl10_mouse(display_long)|uniprotkb:Protein QM homolog(gene name synonym)|uniprotkb:Qm(gene name synonym)|uniprotkb:Rpl10(gene name)|psi-mi:Rpl10(display_short)|uniprotkb:Ribosomal protein L10(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000008682(gene)|ensembl:ENSMUSG00000058443(gene)|ensembl:ENSMUST00000008826(transcript)|ensembl:ENSMUST00000074085(transcript)|ensembl:ENSMUST00000076364(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0097421"(liver regeneration)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:Q6ZWV3|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_443067.1 - - author-confidence:0.09 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9CXU1 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-309355|uniprotkb:Q9DAP5|ensembl:ENSMUSP00000021157 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med31_mouse(display_long)|uniprotkb:Med31(gene name)|psi-mi:Med31(display_short)|uniprotkb:Soh1(gene name synonym)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_080344.2|ensembl:ENSMUSG00000020801(gene)|ensembl:ENSMUST00000021157(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|rcsb pdb:6W1S|reactome:R-MMU-212436 - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:Wy6xli/o/1mNyYP86nqOcIqcRzI10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:O08784 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261057|ensembl:ENSMUSP00000135476|uniprotkb:O08857 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:tcof_mouse(display_long)|uniprotkb:Treacher Collins syndrome protein homolog(gene name synonym)|uniprotkb:Tcof1(gene name)|psi-mi:Tcof1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000024613(gene)|ensembl:ENSMUST00000176630(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003993(Treacher Collins syndrome, treacle)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR017859|mint:O08784|refseq:NP_035682.1 - - author-confidence:0.06 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:oyn9kai+jDLD39W9rDIKMHj3Qgw10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9CY66 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260856|ensembl:ENSMUSP00000029643|uniprotkb:Q80X93|uniprotkb:Q8VDH0|uniprotkb:Q8C6C5 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:gar1_mouse(display_long)|uniprotkb:Nola1(gene name synonym)|uniprotkb:Nucleolar protein family A member 1(gene name synonym)|uniprotkb:snoRNP protein GAR1(gene name synonym)|uniprotkb:Gar1(gene name)|psi-mi:Gar1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000028010(gene)|ensembl:ENSMUST00000029643(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|mint:Q9CY66|reactome:R-MMU-171319|refseq:XP_011238510.1|refseq:NP_080854.1 - - author-confidence:0.21 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:w4y7W3rVMnGQfiS3g/wM6wJtDmc10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9Z1X4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260790|ensembl:ENSMUSP00000065770|uniprotkb:Q8BP80|uniprotkb:Q8K588|uniprotkb:Q8C2H8|uniprotkb:Q812A1|uniprotkb:Q80VD5 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:ilf3_mouse(display_long)|uniprotkb:Ilf3(gene name)|psi-mi:Ilf3(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_001264250.1|ensembl:ENSMUSG00000032178(gene)|ensembl:ENSMUST00000067646(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006479"(protein methylation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q9Z1X4|rcsb pdb:4AT7|rcsb pdb:4AT8|rcsb pdb:4AT9|rcsb pdb:4ATB|rcsb pdb:5DV7|refseq:XP_006510094.1|refseq:NP_001036172.1|refseq:NP_001036173.1|refseq:NP_034691.2|refseq:NP_001264251.1 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:vxZan3L6NAseX1Ib9Z7MQ82CM3E10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q923D4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260940|ensembl:ENSMUSP00000100771 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:sf3b5_mouse(display_long)|uniprotkb:Pre-mRNA-splicing factor SF3b 10 kDa subunit(gene name synonym)|uniprotkb:Sf3b10(gene name synonym)|uniprotkb:Sf3b5(gene name)|psi-mi:Sf3b5(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000078348(gene)|ensembl:ENSMUST00000105139(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR009846(Splicing factor 3B subunit 5/RDS3 complex subunit 10)|interpro:IPR017089(Splicing factor 3B, subunit 5)|mint:Q923D4|reactome:R-MMU-72163|reactome:R-MMU-72165|refseq:NP_780311.2 - - author-confidence:0.09 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:mqP6Bh/N2HYfOkVjIAM9nu17Qro10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:A2ABV5 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-5744924|uniprotkb:Q3TQU3|uniprotkb:Q6P1H5|uniprotkb:Q9R0T1|uniprotkb:Q9WTN9|ensembl:ENSMUSP00000094239 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med14_mouse(display_long)|uniprotkb:Med14(gene name)|psi-mi:Med14(display_short)|uniprotkb:Crsp2(gene name synonym)|uniprotkb:Gm641(gene name synonym)|uniprotkb:Trap170(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_001041673.1|refseq:NP_036135.3|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|rcsb pdb:6W1S|reactome:R-MMU-212436|ensembl:ENSMUSG00000064127(gene)|ensembl:ENSMUST00000096495(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II) - - author-confidence:0.06 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:zYS7ClZGBQS0njhhSZ9xew2FSLI10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9CQ39 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260960|ensembl:ENSMUSP00000032429|ensembl:ENSMUSP00000145512|uniprotkb:Q921I5 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med21_mouse(display_long)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:Srb7(gene name synonym)|uniprotkb:Surb7(gene name synonym)|uniprotkb:Med21(gene name)|psi-mi:Med21(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000030291(gene)|ensembl:ENSMUST00000032429(transcript)|ensembl:ENSMUST00000204040(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|rcsb pdb:6W1S|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:NP_079591.1|dip:DIP-59522N - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:4a1HoRbOTd2Nm/gDGbidH5rrMbg10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q80YQ2 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-5745001|uniprotkb:Q6ZPV7|uniprotkb:Q8CEC3|uniprotkb:Q8K587|uniprotkb:Q9CXY8 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med23_mouse(display_long)|uniprotkb:Med23(gene name)|psi-mi:Med23(display_short)|uniprotkb:Crsp3(gene name synonym)|uniprotkb:Kiaa1216(gene name synonym)|uniprotkb:Sur2(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_001159888.1|refseq:NP_081623.3|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:2000409"(positive regulation of T cell extravasation)|interpro:IPR021629|rcsb pdb:6W1S|dip:DIP-59234N|reactome:R-MMU-212436 - - author-confidence:0.01 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:unJwhtOAP16TniaelImM6E3JM8o10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q924H2 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260935|ensembl:ENSMUSP00000012259|uniprotkb:G3X8S4 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med15_mouse(display_long)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Pcqap(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:Med15(gene name)|psi-mi:Med15(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000012114(gene)|ensembl:ENSMUST00000012259(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|interpro:IPR019087|interpro:IPR036529|mint:Q924H2|rcsb pdb:6W1S|reactome:R-MMU-212436|dip:DIP-59237N|refseq:NP_291087.2 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:mZasSGGG3iCf4B+EFvrHwfeRm0I10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q7TT28 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260805|ensembl:ENSMUSP00000049705|uniprotkb:Q3UMP1|uniprotkb:Q9DA29|uniprotkb:Q6NSQ6|uniprotkb:Q69ZR0|uniprotkb:Q6PI95 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rexo1_mouse(display_long)|uniprotkb:Kiaa1138(gene name synonym)|uniprotkb:Tceb3bp1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 3-binding protein 1(gene name synonym)|uniprotkb:Rexo1(gene name)|psi-mi:Rexo1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000047417(gene)|ensembl:ENSMUST00000057910(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016604"(nuclear body)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR031736|interpro:IPR034922|interpro:IPR036397|refseq:NP_080128.2 - - author-confidence:0.07 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:lGeQya1eGY30Te+KfpmavV2RjDo10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9ESU6 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260864|ensembl:ENSMUSP00000113070|uniprotkb:Q8VHF7|uniprotkb:Q8VHF8|uniprotkb:B0V2V7 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:brd4_mouse(display_long)|uniprotkb:Mcap(gene name synonym)|uniprotkb:Mitotic chromosome-associated protein(gene name synonym)|uniprotkb:Brd4(gene name)|psi-mi:Brd4(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000024002(gene)|ensembl:ENSMUST00000121285(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034211"(GTP-dependent protein kinase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR031354|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|mint:Q9ESU6|rcsb pdb:2DWW|rcsb pdb:2JNS|rcsb pdb:3JVJ|rcsb pdb:3JVK|rcsb pdb:3JVL|rcsb pdb:3JVM|rcsb pdb:3MUK|rcsb pdb:3MUL|refseq:XP_006524751.1|refseq:XP_006524752.1|refseq:NP_065254.3|refseq:NP_932762.2|dip:DIP-42181N - - author-confidence:0.08 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:aD51lXIT5Ap1qkTwaWqQfkDcHA810090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P20152 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid://GDvGAXOR4hUXNtVpnZefex5v410090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:O70422 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261007|ensembl:ENSMUSP00000001565|ensembl:ENSMUSP00000124335 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:tf2h4_mouse(display_long)|uniprotkb:Basic transcription factor 2 52 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 4(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p52 subunit(gene name synonym)|uniprotkb:Gtf2h4(gene name)|psi-mi:Gtf2h4(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000001524(gene)|ensembl:ENSMUST00000001565(transcript)|ensembl:ENSMUST00000160734(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR040662|mint:O70422|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|interpro:IPR004598(Transcription factor Tfb2)|reactome:R-MMU-77075|refseq:XP_006523731.1|refseq:XP_006523732.1|refseq:NP_034494.1 - - author-confidence:0.06 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:O++CxJxtFggB6uTyhpVO+5LcN/410090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q8VCD5 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-5744951|uniprotkb:Q8BYS6|uniprotkb:Q99KQ1|ensembl:ENSMUSP00000034411 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med17_mouse(display_long)|uniprotkb:Med17(gene name)|psi-mi:Med17(display_short)|uniprotkb:Crsp6(gene name synonym)|uniprotkb:Trap80(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_659182.1|ensembl:ENSMUSG00000031935(gene)|ensembl:ENSMUST00000034411(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|rcsb pdb:6W1S|reactome:R-MMU-212436|dip:DIP-48407N - - author-confidence:0.03 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:RphTDePi36YqZFcRmkcobUnPd7I10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P62852 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260945|ensembl:ENSMUSP00000079180|ensembl:ENSMUSP00000149401|uniprotkb:P25111 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rs25_mouse(display_long)|uniprotkb:Rps25(gene name)|psi-mi:Rps25(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000009927(gene)|ensembl:ENSMUST00000080300(transcript)|ensembl:ENSMUST00000216867(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR004977(Ribosomal protein S25)|interpro:IPR036388|mint:P62852|reactome:R-MMU-156827|reactome:R-MMU-1799339|go:"GO:0045202"(synapse)|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_077228.1 - - author-confidence:0.24 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:7TqA4Q6+6VMzrzaUrACbwtJKfOM10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9D8C6 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260909|ensembl:ENSMUSP00000019067|uniprotkb:Q3V4D0 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med11_mouse(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:Med11(gene name)|psi-mi:Med11(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000018923(gene)|ensembl:ENSMUST00000019067(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|interpro:IPR019404|mint:Q9D8C6|rcsb pdb:6W1S|refseq:NP_079673.2 - - author-confidence:0.14 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:GzL0hfZ1n8eanV99Mqb1JTL4OXI10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P51827 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-529725|uniprotkb:Q80WS6|ensembl:ENSMUSP00000159147 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:aff3_mouse(display_long)|uniprotkb:Lymphoid nuclear protein related to AF4(gene name synonym)|uniprotkb:Laf4(gene name synonym)|uniprotkb:Aff3(gene name)|psi-mi:Aff3(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000037138(gene)|ensembl:ENSMUST00000238906(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0032783"(super elongation complex)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|interpro:IPR007797(AF-4 proto-oncoprotein)|interpro:IPR043639|interpro:IPR043640 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:Y2wXjyjz6iXp9uwmTRYNmkPkhZg10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q8K019 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2536273|uniprotkb:Q8C2E9|uniprotkb:Q9CSW5|uniprotkb:Q8BNZ0|ensembl:ENSMUSP00000043583 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:bclf1_mouse(display_long)|uniprotkb:Bclaf1(gene name)|psi-mi:Bclaf1(display_short)|uniprotkb:Btf(gene name synonym)|uniprotkb:Kiaa0164(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000037608(gene)|ensembl:ENSMUST00000043881(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR026668|interpro:IPR029199|mint:Q8K019|refseq:NP_001020563.1|refseq:NP_722482.1 - - author-confidence:0.24 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:+9NQPsUgV77P3yH9iK0ZRDIOioM10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q922U1 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261050|ensembl:ENSMUSP00000015892|ensembl:ENSMUSP00000124950|uniprotkb:Q9D6C6|uniprotkb:Q3TJH4 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:prpf3_mouse(display_long)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)|uniprotkb:Prpf3(gene name)|psi-mi:Prpf3(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUST00000161476(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|interpro:IPR036483|mint:Q922U1|reactome:R-MMU-72163|ensembl:ENSMUSG00000015748(gene)|ensembl:ENSMUST00000015892(transcript)|refseq:NP_001303680.1|refseq:NP_081817.2 - - author-confidence:0.27 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:i91ATWXZhjB1NLoCk44aTm9ovm010090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9QWV9 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2655009|uniprotkb:Q9Z0U7|uniprotkb:Q3V0G4|ensembl:ENSMUSP00000012104|ensembl:ENSMUSP00000126874 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:ccnt1_mouse(display_long)|uniprotkb:Ccnt1(gene name)|psi-mi:Ccnt1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_033963.1|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:Q9QWV9|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|ensembl:ENSMUSG00000011960(gene)|ensembl:ENSMUST00000012104(transcript)|ensembl:ENSMUST00000169707(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated) - - author-confidence:0.03 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:0OHMWIM5Vb9/Whq5PdvunZdi1F010090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P09405 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-641864|uniprotkb:Q548M9|uniprotkb:Q61991|uniprotkb:Q8BQD8|uniprotkb:Q99K50|ensembl:ENSMUSP00000027438 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:nucl_mouse(display_long)|uniprotkb:Protein C23(gene name synonym)|uniprotkb:Ncl(gene name)|psi-mi:Ncl(display_short)|uniprotkb:Nuc(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_035010.3|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990631"(ErbB-4 class receptor binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000232"(regulation of rRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P09405|reactome:R-MMU-6791226|go:"GO:0005634"(nucleus)|ensembl:ENSMUSG00000026234(gene)|ensembl:ENSMUST00000027438(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding) - - author-confidence:0.05 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:NkPifysnX6CafgtN+Ko/p4aBqGE10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:E9Q5C9 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261018|ensembl:ENSMUSP00000128331|ensembl:ENSMUSP00000157687|intact:EBI-8340445|intact:MINT-4115376|uniprotkb:Q3TKZ9|uniprotkb:Q3UBB6|uniprotkb:Q3UI16|uniprotkb:Q6ZQK6|uniprotkb:Q8CE21|uniprotkb:Q3U6W2 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:nolc1_mouse(display_long)|uniprotkb:Nolc1(gene name)|psi-mi:Nolc1(display_short)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Kiaa0035(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000015176(gene)|ensembl:ENSMUST00000165017(transcript)|ensembl:ENSMUST00000235620(transcript)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0062064"(box C/D snoRNP complex binding)|go:"GO:0062065"(box H/ACA snoRNP complex binding)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|mint:E9Q5C9|go:"GO:0031429"(box H/ACA snoRNP complex)|refseq:NP_001034440.1|refseq:NP_001034442.1|refseq:NP_444316.2|refseq:NP_001034441.1 - - author-confidence:0.06 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:jfyg4IEO5fJn4YFTQ9vjM/m8lmQ10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9CQI9 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-309220|ensembl:ENSMUSP00000042204 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med30_mouse(display_long)|uniprotkb:Med30(gene name)|psi-mi:Med30(display_short)|uniprotkb:Thrap6(gene name synonym)|uniprotkb:Trap25(gene name synonym)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_081488.1|ensembl:ENSMUSG00000038622(gene)|ensembl:ENSMUST00000037115(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|rcsb pdb:6W1S|reactome:R-MMU-212436 - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:SMuv0OCFF6h3tHPDgOZBHSBFAHw10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q6DFW4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260951|ensembl:ENSMUSP00000140250|uniprotkb:Q8C8Y7|uniprotkb:Q3UZA3|uniprotkb:O70396|uniprotkb:Q3UYX9 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:nop58_mouse(display_long)|uniprotkb:MSSP(gene name synonym)|uniprotkb:Nol5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:SIK-similar protein(gene name synonym)|uniprotkb:Nop58(gene name)|psi-mi:Nop58(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000026020(gene)|ensembl:ENSMUST00000191142(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q6DFW4|reactome:R-MMU-4570464|reactome:R-MMU-6791226|refseq:NP_061356.2 - - author-confidence:0.01 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:gx/F5iCI7SIdIqpZobsk4CcPd/I10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P84104 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2550426|ensembl:ENSMUSP00000117045|uniprotkb:O08831|uniprotkb:P23152|uniprotkb:Q564E9 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:srsf3_mouse(display_long)|uniprotkb:Sfrs3(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 3(gene name synonym)|uniprotkb:Srsf3(gene name)|psi-mi:Srsf3(display_short)|uniprotkb:Srp20(gene name synonym)|uniprotkb:X16(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRP20(gene name synonym)|uniprotkb:Protein X16(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000071172(gene)|ensembl:ENSMUST00000130216(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P84104|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|refseq:NP_038691.1 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:BcfyCj2cNNTH1igANKpvh4IHDVU10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q99J62 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-1180260|ensembl:ENSMUSP00000023598 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rfc4_mouse(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Rfc4(gene name)|psi-mi:Rfc4(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_663455.1|ensembl:ENSMUSG00000022881(gene)|ensembl:ENSMUST00000023598(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:Q99J62|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-110320|reactome:R-MMU-174411|reactome:R-MMU-176187|reactome:R-MMU-5651801|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6804756|reactome:R-MMU-69091|reactome:R-MMU-69473 - - author-confidence:0.15 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:/b4330329gTjg/4g79oGZvdIFQc10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9CXY6 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2312782|uniprotkb:Q3U083|uniprotkb:Q5RKG0|uniprotkb:Q8CCY9|uniprotkb:Q99KS3|ensembl:ENSMUSP00000001042 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:ilf2_mouse(display_long)|uniprotkb:Ilf2(gene name)|psi-mi:Ilf2(display_short)|uniprotkb:Nf45(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_080650.1|ensembl:ENSMUSG00000001016(gene)|ensembl:ENSMUST00000001042(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q9CXY6|rcsb pdb:4AT7|rcsb pdb:4AT8|rcsb pdb:4AT9|rcsb pdb:4ATB|reactome:R-MMU-6798695 - - author-confidence:0.14 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q921D4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-5745383|uniprotkb:Q3TAK5|uniprotkb:Q8BTP9|ensembl:ENSMUSP00000125156 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med6_mouse(display_long)|uniprotkb:Med6(gene name)|psi-mi:Med6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_081489.2|refseq:NP_001334313.1|refseq:NP_001334315.1|dip:DIP-60703N|ensembl:ENSMUSG00000002679(gene)|ensembl:ENSMUST00000161211(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|rcsb pdb:6W1S|reactome:R-MMU-212436 - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:zmKsMA5JwAtTd32b4TAbAnwHmxs10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9CZB6 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-5745319|uniprotkb:Q3UGV1|uniprotkb:Q91VN3|uniprotkb:Q9CWV8|uniprotkb:Q9D0V9|ensembl:ENSMUSP00000020665|ensembl:ENSMUSP00000104855|ensembl:ENSMUSP00000131852 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med7_mouse(display_long)|uniprotkb:Med7(gene name)|psi-mi:Med7(display_short)|uniprotkb:Crsp9(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_001098000.1|refseq:NP_001098026.1|refseq:NP_001098027.1|refseq:NP_079702.3|refseq:XP_006533994.1|refseq:XP_006533995.1|refseq:XP_006533996.1|refseq:XP_006533997.1|ensembl:ENSMUSG00000020397(gene)|ensembl:ENSMUST00000020665(transcript)|ensembl:ENSMUST00000109232(transcript)|ensembl:ENSMUST00000170928(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|rcsb pdb:6W1S|reactome:R-MMU-212436 - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:GEXDK4CF6eXsf1RC5geoPYjttVs10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P62855 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260985|ensembl:ENSMUSP00000026420|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:P02383 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rs26_mouse(display_long)|uniprotkb:Rps26(gene name)|psi-mi:Rps26(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000025362(gene)|ensembl:ENSMUST00000026420(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|mint:P62855|refseq:NP_038793.2 - - author-confidence:0.17 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9R0X0 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-398698|uniprotkb:Q3V418|uniprotkb:Q6PAR6|uniprotkb:Q3UJQ7|ensembl:ENSMUSP00000024778 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med20_mouse(display_long)|uniprotkb:Med20(gene name)|psi-mi:Med20(display_short)|uniprotkb:Trfp(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_064432.1|ensembl:ENSMUSG00000092558(gene)|ensembl:ENSMUST00000024778(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR013921(TATA-binding related factor)|rcsb pdb:6W1S|reactome:R-MMU-212436 - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:BtpjoTqQBoyi+qOsKtOv2ylLVdU10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P99027 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261122|ensembl:ENSMUSP00000101625|ensembl:ENSMUSP00000101626|ensembl:ENSMUSP00000081474|uniprotkb:Q9CQ99|uniprotkb:Q9CZJ8|uniprotkb:Q3TKY3 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rla2_mouse(display_long)|uniprotkb:Rplp2(gene name)|psi-mi:Rplp2(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUST00000084434(transcript)|ensembl:ENSMUST00000106003(transcript)|ensembl:ENSMUST00000106004(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0045202"(synapse)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P99027|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000025508(gene)|refseq:XP_006536292.1|refseq:NP_080296.3 - - author-confidence:0.23 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:GYHP8hzpsOXoDDDnyOOBTMeIozg10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9JIB4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260800|ensembl:ENSMUSP00000065228 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:tf2h2_mouse(display_long)|uniprotkb:Basic transcription factor 2 44 kDa subunit(gene name synonym)|uniprotkb:Btf2p44(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 2(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p44 subunit(gene name synonym)|uniprotkb:Gtf2h2(gene name)|psi-mi:Gtf2h2(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUST00000066984(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|ensembl:ENSMUSG00000021639(gene)|refseq:NP_071294.3 - - author-confidence:0.01 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:B1sNNBPY99dly+ZymdKJeaj6nWA10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P62751 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-4286547|uniprotkb:P29316|uniprotkb:P39024|uniprotkb:Q92774|ensembl:ENSMUSP00000099541 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rl23a_mouse(display_long)|uniprotkb:Rpl23a(gene name)|psi-mi:Rpl23a(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_997406.1|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62751|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000058546(gene)|ensembl:ENSMUST00000102483(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|dip:DIP-59973N - - author-confidence:0.03 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:B2RY56 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260843|ensembl:ENSMUSP00000048470|uniprotkb:Q9CT49|uniprotkb:Q6NWW2|uniprotkb:Q91XE6|uniprotkb:Q8BVT8|uniprotkb:Q3UQU7|uniprotkb:Q3U976|uniprotkb:Q9CT27|uniprotkb:Q3TPH6 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rbm25_mouse(display_long)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:Rbm25(gene name)|psi-mi:Rbm25(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000010608(gene)|ensembl:ENSMUST00000048155(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|mint:B2RY56|refseq:XP_006516230.1|refseq:XP_006516231.1|refseq:NP_081625.3|refseq:XP_006516232.1|refseq:XP_017170651.1 - - author-confidence:0.09 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:VreU6xG6nDlSvUqQwe4vabbXrRU10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q569Z6 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2536252|ensembl:ENSMUSP00000079722 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:tr150_mouse(display_long)|uniprotkb:Thrap3(gene name)|psi-mi:Thrap3(display_short)|uniprotkb:Trap150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000043962(gene)|ensembl:ENSMUST00000080919(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR026667|interpro:IPR029199|go:"GO:0008380"(RNA splicing)|refseq:XP_011238805.1|refseq:NP_666265.3|refseq:XP_006503104.1 - - author-confidence:0.23 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:Cb0vHuEX3Ew27z2gvfC/36tdeYE10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q03147 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261044|ensembl:ENSMUSP00000088845|uniprotkb:Q99KK3 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:cdk7_mouse(display_long)|uniprotkb:39 kDa protein kinase(gene name synonym)|uniprotkb:CDK-activating kinase(gene name synonym)|uniprotkb:CR4 protein kinase(gene name synonym)|uniprotkb:Cak(gene name synonym)|uniprotkb:Cdkn7(gene name synonym)|uniprotkb:Cell division protein kinase 7(gene name synonym)|uniprotkb:Crk4(gene name synonym)|uniprotkb:Mo15(gene name synonym)|uniprotkb:Mpk-7(gene name synonym)|uniprotkb:Protein-tyrosine kinase MPK-7(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex kinase subunit(gene name synonym)|uniprotkb:Cdk7(gene name)|psi-mi:Cdk7(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037770|mint:Q03147|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-69202|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-69656|go:"GO:0050821"(protein stabilization)|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-8939236|ensembl:ENSMUSG00000069089(gene)|ensembl:ENSMUST00000091299(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|refseq:NP_034004.2 - - author-confidence:0.12 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:YJv2CPyRiz6d3jHrPxSh5J8SHS010090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9D824 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-4284884|uniprotkb:Q8BWX7|uniprotkb:Q99LH0|uniprotkb:Q9DBB2|ensembl:ENSMUSP00000109164 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:fip1_mouse(display_long)|uniprotkb:Fip1l1(gene name)|psi-mi:Fip1l1(display_short)|uniprotkb:FIP1-like 1 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_077145.2|refseq:NP_001153045.1|refseq:NP_001153046.1|ensembl:ENSMUSG00000029227(gene)|ensembl:ENSMUST00000113536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q9D824|reactome:R-MMU-159231|reactome:R-MMU-72163|reactome:R-MMU-73856|reactome:R-MMU-72187|reactome:R-MMU-77595 - - author-confidence:0.19 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:HUvxO7hcgX/waTp9pYqFuxXH9Ko10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q08288 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260874|ensembl:ENSMUSP00000084791|ensembl:ENSMUSP00000109741|uniprotkb:Q9D9X2 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:lyar_mouse(display_long)|uniprotkb:Ly1 antibody-reactive protein(gene name synonym)|uniprotkb:Protein expressed in male leptotene and zygotene spermatocytes 264(gene name synonym)|uniprotkb:Lyar(gene name)|psi-mi:Lyar(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000067367(gene)|ensembl:ENSMUST00000087514(transcript)|ensembl:ENSMUST00000114106(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|rcsb pdb:1WJV|mint:Q08288|refseq:XP_006503822.1|refseq:XP_006503823.1|refseq:XP_006503824.1|refseq:XP_006503825.1|refseq:XP_006503826.1|refseq:XP_006503827.1|refseq:NP_079557.2 - - author-confidence:0.16 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:voQ+0UWDj0wO+gD3jZwt/yb2Z/o10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q6ZPL9 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260901|ensembl:ENSMUSP00000070279|uniprotkb:Q3U460|uniprotkb:Q149H5|uniprotkb:Q8BZR1 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:ddx55_mouse(display_long)|uniprotkb:DEAD box protein 55(gene name synonym)|uniprotkb:Kiaa1595(gene name synonym)|uniprotkb:Ddx55(gene name)|psi-mi:Ddx55(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000029389(gene)|ensembl:ENSMUST00000071057(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313|interpro:IPR027417|refseq:NP_080685.2 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:eQ/R6J7rkH+BUxnW6eWNK85H/V010090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q52KI8 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261023|uniprotkb:Q9CVG5|uniprotkb:E9QNW8|uniprotkb:O70495 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:srrm1_mouse(display_long)|uniprotkb:Plenty-of-prolines 101(gene name synonym)|uniprotkb:Pop101(gene name synonym)|uniprotkb:Srrm1(gene name)|psi-mi:Srrm1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-9013418|reactome:R-MMU-9013422|mint:Q52KI8|interpro:IPR002483(Splicing factor PWI)|refseq:NP_058079.2|interpro:IPR036483 - - author-confidence:0.14 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:3KzIJ4KWj8b66l+g5Cqq8JPZ5bQ10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q8BFQ4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260783|ensembl:ENSMUSP00000020490|uniprotkb:Q8VEE8|uniprotkb:Q8K2G5 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:wdr82_mouse(display_long)|uniprotkb:Cdw5(gene name synonym)|uniprotkb:Wdr82(gene name)|psi-mi:Wdr82(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000020257(gene)|ensembl:ENSMUST00000020490(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q8BFQ4|refseq:NP_084172.1 - - author-confidence:0.29 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9CXU0 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260880|ensembl:ENSMUSP00000022089|uniprotkb:Q3U0W8|uniprotkb:Q80VV0 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med10_mouse(display_long)|uniprotkb:D13Wsu50e(gene name synonym)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Med10(gene name)|psi-mi:Med10(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000021598(gene)|ensembl:ENSMUST00000022089(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019145|rcsb pdb:6W1S|reactome:R-MMU-212436|refseq:NP_613062.1 - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:AfEfa2zgRYMoqr1jicnJD314Pas10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q0P678 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-4285772|uniprotkb:Q3TKW3|uniprotkb:Q52KI3|uniprotkb:Q6KAL8|uniprotkb:Q9CU64|ensembl:ENSMUSP00000090761 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:zch18_mouse(display_long)|uniprotkb:Zc3h18(gene name)|psi-mi:Zc3h18(display_short)|uniprotkb:Nhn1(gene name synonym)|uniprotkb:Nuclear protein NHN1(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUST00000093073(transcript)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0050779"(RNA destabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041367|refseq:NP_001025164.1|refseq:NP_001025165.1|refseq:NP_001297579.1|ensembl:ENSMUSG00000017478(gene) - - author-confidence:0.05 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:yQXtDYpTOE6hdaKBFQskL/GDgvw10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P62754 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2000022|uniprotkb:P08227|uniprotkb:P10660|ensembl:ENSMUSP00000099878 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:rs6_mouse(display_long)|uniprotkb:Rps6(gene name)|psi-mi:Rps6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_033122.1|refseq:XP_011238179.1|ensembl:ENSMUSG00000028495(gene)|ensembl:ENSMUST00000102814(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|interpro:IPR018282|mint:P62754|reactome:R-MMU-156827|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|dip:DIP-42772N|reactome:R-MMU-166208|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 - - author-confidence:0.19 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:beDuXCIqL99V9JlVfpzx7MdpH6810090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:O88573 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260923 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:aff1_mouse(display_long)|uniprotkb:Mllt2(gene name synonym)|uniprotkb:Mllt2h(gene name synonym)|uniprotkb:Proto-oncogene AF4(gene name synonym)|uniprotkb:Aff1(gene name)|psi-mi:Aff1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0032783"(super elongation complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR043639|interpro:IPR043640|interpro:IPR007797(AF-4 proto-oncoprotein) - - author-confidence:0.05 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:etzEr1TJ2QC1t7dvr5cmu2OZrcs10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9D6Z1 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-527254|uniprotkb:Q3UD45|uniprotkb:Q8BVL1|uniprotkb:Q8VDT2|uniprotkb:Q99LT8|uniprotkb:Q9CT15|ensembl:ENSMUSP00000099487 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:nop56_mouse(display_long)|uniprotkb:Nop56(gene name)|psi-mi:Nop56(display_short)|uniprotkb:Nol5a(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_077155.2|ensembl:ENSMUSG00000027405(gene)|ensembl:ENSMUST00000103198(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q9D6Z1|reactome:R-MMU-6791226 - - author-confidence:0.15 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:5darNL7hBt/XPnvcm0hiVxx7WDY10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q99KP6 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260977|uniprotkb:Q4ADG5|ensembl:ENSMUSP00000025642|uniprotkb:Q8BKZ5|uniprotkb:Q3TP64|uniprotkb:Q8BVQ4 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:prp19_mouse(display_long)|uniprotkb:Nuclear matrix protein 200(gene name synonym)|uniprotkb:PRP19/PSO4 homolog(gene name synonym)|uniprotkb:Prp19(gene name synonym)|uniprotkb:Senescence evasion factor(gene name synonym)|uniprotkb:Snev(gene name synonym)|uniprotkb:Prpf19(gene name)|psi-mi:Prpf19(display_short)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000024735(gene)|ensembl:ENSMUST00000025642(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005819"(spindle)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|interpro:IPR020472|interpro:IPR036322|interpro:IPR038959|mint:Q99KP6|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-72163|interpro:IPR019775|refseq:NP_001240772.1|refseq:NP_001240773.1|refseq:NP_598890.1 - - author-confidence:0.27 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:y9TwQBT+caDGqphA61AR5ysoqRg10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q8R409 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261031|ensembl:ENSMUSP00000057339 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:hexi1_mouse(display_long)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Clp1(gene name synonym)|uniprotkb:Hexim1(gene name)|psi-mi:Hexim1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000048878(gene)|ensembl:ENSMUST00000053063(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:Q8R409|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_620092.1 - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:OunbkHzHniuwaUbUIZTRufo/KfM10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P84089 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2551866|ensembl:ENSMUSP00000021559|ensembl:ENSMUSP00000147411|uniprotkb:Q14259|uniprotkb:P70659 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:erh_mouse(display_long)|uniprotkb:Erh(gene name)|psi-mi:Erh(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000021131(gene)|ensembl:ENSMUSG00000063412(gene)|ensembl:ENSMUST00000021559(transcript)|ensembl:ENSMUST00000080152(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84089|rcsb pdb:1WWQ|rcsb pdb:1WZ7|refseq:NP_031977.1 - - author-confidence:0.2 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q3TVI4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261072|ensembl:ENSMUSP00000053678|ensembl:ENSMUSP00000102652|uniprotkb:Q9D4C7 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:hexi2_mouse(display_long)|uniprotkb:Hexim2(gene name)|psi-mi:Hexim2(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000043372(gene)|ensembl:ENSMUST00000062530(transcript)|ensembl:ENSMUST00000107037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|interpro:IPR024872|interpro:IPR024876|refseq:XP_006534291.1|refseq:XP_006534292.1|refseq:XP_006534293.1|refseq:XP_006534294.1|refseq:NP_001123987.1|refseq:NP_001123988.1|refseq:NP_081934.1 - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:jZd4x7+NPSqTaf2h6vVJDUaS2rk10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q9ERF3 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6094557|uniprotkb:Q3U562|uniprotkb:Q9CZP1|ensembl:ENSMUSP00000056359|ensembl:ENSMUSP00000113560 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:wdr61_mouse(display_long)|uniprotkb:Wdr61(gene name)|psi-mi:Wdr61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_001020546.1|refseq:NP_075680.1|ensembl:ENSMUSG00000061559(gene)|ensembl:ENSMUST00000051822(transcript)|ensembl:ENSMUST00000121204(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9ERF3|reactome:R-MMU-112382|reactome:R-MMU-429958|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654 - - author-confidence:0.03 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:r5TxJiuiFNk5dUDuhzCqFfFXX/M10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q8K3A9 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260834|ensembl:ENSMUSP00000031740|uniprotkb:Q3UT64|uniprotkb:Q91W35|uniprotkb:Q2YFS5|uniprotkb:Q3U465 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:mepce_mouse(display_long)|uniprotkb:Bcdin3(gene name synonym)|uniprotkb:Bipl1(gene name synonym)|uniprotkb:D5Wsu46e(gene name synonym)|uniprotkb:Mepce(gene name)|psi-mi:Mepce(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000029726(gene)|ensembl:ENSMUST00000031740(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|refseq:NP_659162.3 - - author-confidence:0.02 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:PK/X6CkfJNZaHmcdBnXlK64t9r410090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:P70379 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261098|uniprotkb:Q3KNZ6|uniprotkb:Q9JHL9|uniprotkb:Q8BST0 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:fgf14_mouse(display_long)|uniprotkb:Fhf4(gene name synonym)|uniprotkb:Fibroblast growth factor homologous factor 4(gene name synonym)|uniprotkb:Fgf14(gene name)|psi-mi:Fgf14(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007254"(JNK cascade)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0050905"(neuromuscular process)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:0048167"(regulation of synaptic plasticity)|refseq:XP_011243254.1|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|refseq:NP_034331.2|interpro:IPR028284|reactome:R-MMU-5576892 - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:cusO6gC4UpmsgXYGXHqY1/SV5XI10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q05CL8 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6260966|ensembl:ENSMUSP00000029588|uniprotkb:Q8VDW3|uniprotkb:Q9CUQ5|uniprotkb:Q3TSC2|uniprotkb:Q9CSI9|uniprotkb:Q8K2Y6|uniprotkb:Q9CSI2 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:larp7_mouse(display_long)|uniprotkb:D3Wsu161e(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:Larp7(gene name)|psi-mi:Larp7(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000027968(gene)|ensembl:ENSMUST00000029588(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0036093"(germ cell proliferation)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990438"(U6 2'-O-snRNA methylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:Q05CL8|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:NP_613059.2 - - author-confidence:0.01 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:LXPfM/sQrPvcSwU7ti5T93JQ6+k10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q921K2 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261012|ensembl:ENSMUSP00000027777 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:q921k2_mouse(display_long)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUST00000027777(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:Q921K2|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|ensembl:ENSMUSG00000026496(gene)|refseq:NP_031441.2 - - author-confidence:0.2 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:LeuW0EFJDL/7bR1fRoDZvwA2g/A10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q61545 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-1606991|uniprotkb:Q9D2P0|ensembl:ENSMUSP00000078867 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:ews_mouse(display_long)|uniprotkb:Ewsr1(gene name)|psi-mi:Ewsr1(display_short)|uniprotkb:Ews(gene name synonym)|uniprotkb:Ewsh(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_031994.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q61545|ensembl:ENSMUSG00000009079(gene)|ensembl:ENSMUST00000079949(transcript) - - author-confidence:0.1 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:bvajg+ZT71/K+6hwdHFdOewgvrw10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q7TPV4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-1373622|uniprotkb:O35851|uniprotkb:Q80Y66|uniprotkb:Q8R4X2|uniprotkb:Q99KP0|ensembl:ENSMUSP00000044827 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:mbb1a_mouse(display_long)|uniprotkb:Mybbp1a(gene name)|psi-mi:Mybbp1a(display_short)|uniprotkb:P160(gene name synonym)|uniprotkb:Myb-binding protein of 160 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_058056.2|dip:DIP-39831N|ensembl:ENSMUSG00000040463(gene)|ensembl:ENSMUST00000045633(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR016024(Armadillo-type fold)|mint:Q7TPV4|reactome:R-MMU-5250924 - - author-confidence:0.22 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:rt1TQLZB7JNBkpt3DooDAlzOYCo10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q6ZQ03 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261106|uniprotkb:Q8BNC8|uniprotkb:Q3TPA6|uniprotkb:Q9JHC1 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:fnbp4_mouse(display_long)|uniprotkb:Fbp30(gene name synonym)|uniprotkb:Formin-binding protein 30(gene name synonym)|uniprotkb:Kiaa1014(gene name synonym)|uniprotkb:Fnbp4(gene name)|psi-mi:Fnbp4(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0016607"(nuclear speck)|mint:Q6ZQ03|interpro:IPR001202(WW/Rsp5/WWP)|refseq:NP_061298.1|interpro:IPR036020 - - author-confidence:0.17 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:rToxA1wcqp7yyxXU9kFxB5PkXgo10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q8BHZ4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261115|ensembl:ENSMUSP00000102976|uniprotkb:Q80XM1 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:zn592_mouse(display_long)|uniprotkb:Kiaa0211(gene name synonym)|uniprotkb:Zfp592(gene name synonym)|uniprotkb:Znf592(gene name)|psi-mi:Znf592(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000005621(gene)|ensembl:ENSMUST00000107353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041697|mint:Q8BHZ4|refseq:NP_848822.2 - - author-confidence:0 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:eTnikXtxcsynfo8/ZrEWL3NKL8g10090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q62018 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-644452|uniprotkb:Q3UFF5|uniprotkb:Q3UY40|uniprotkb:Q66JX4|uniprotkb:Q7TPS6|uniprotkb:Q8BND9|uniprotkb:Q8BRD1|uniprotkb:Q8C9W7|uniprotkb:Q8C9Y3|uniprotkb:Q8CHI1|ensembl:ENSMUSP00000005749 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:ctr9_mouse(display_long)|uniprotkb:SH2 domain-binding protein 1(gene name synonym)|uniprotkb:Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa(gene name synonym)|uniprotkb:Ctr9(gene name)|psi-mi:Ctr9(display_short)|uniprotkb:Kiaa0155(gene name synonym)|uniprotkb:Sh2bp1(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6260872|imex:IM-17619-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_033457.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0005634"(nucleus)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q62018|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654|go:"GO:0071222"(cellular response to lipopolysaccharide)|ensembl:ENSMUSG00000005609(gene)|ensembl:ENSMUST00000005749(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching) - - author-confidence:0.03 figure legend:table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2018/02/26 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:D1n7ZSSSZL7dLYvcuEkIkttdmg810090 intact-crc:2F1A695DDE417B53|rigid:bweyGNoHm+68/l2+fpNJbOQE/Sc false biotin tag:c-c|v5 tag:c-c isotope label:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J95 uniprotkb:Q03147 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261044|ensembl:ENSMUSP00000088845|uniprotkb:Q99KK3 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:cdk7_mouse(display_long)|uniprotkb:39 kDa protein kinase(gene name synonym)|uniprotkb:CDK-activating kinase(gene name synonym)|uniprotkb:CR4 protein kinase(gene name synonym)|uniprotkb:Cak(gene name synonym)|uniprotkb:Cdkn7(gene name synonym)|uniprotkb:Cell division protein kinase 7(gene name synonym)|uniprotkb:Crk4(gene name synonym)|uniprotkb:Mo15(gene name synonym)|uniprotkb:Mpk-7(gene name synonym)|uniprotkb:Protein-tyrosine kinase MPK-7(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex kinase subunit(gene name synonym)|uniprotkb:Cdk7(gene name)|psi-mi:Cdk7(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6261590|imex:IM-17619-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037770|mint:Q03147|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-69202|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-69656|go:"GO:0050821"(protein stabilization)|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-8939236|ensembl:ENSMUSG00000069089(gene)|ensembl:ENSMUST00000091299(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|refseq:NP_034004.2 - - - figure legend:fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2014/10/16 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:YJv2CPyRiz6d3jHrPxSh5J8SHS010090 intact-crc:9184A40205C61267|rigid:KNgRIJAZNw7p94PUaeECYnxA5XQ false v5 tag:c-c|biotin tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99J95 uniprotkb:Q9ESC8 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261083|ensembl:ENSMUSP00000051479|uniprotkb:B2RST9|uniprotkb:Q8C6W3|uniprotkb:Q8C6K4|uniprotkb:Q8CCH3 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:aff4_mouse(display_long)|uniprotkb:Alf4(gene name synonym)|uniprotkb:Aff4(gene name)|psi-mi:Aff4(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6261590|imex:IM-17619-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000049470(gene)|ensembl:ENSMUST00000060945(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035327"|interpro:IPR007797(AF-4 proto-oncoprotein)|interpro:IPR043639|interpro:IPR043640|mint:Q9ESC8|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955|go:"GO:0032783"(super elongation complex)|refseq:XP_011247633.1|refseq:NP_291043.1 - - - figure legend:fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2014/10/16 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:/pYgaSgjBhwmauoRLYO1WIskmzU10090 intact-crc:9184A40205C61267|rigid:KNgRIJAZNw7p94PUaeECYnxA5XQ false v5 tag:c-c|biotin tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99J95 uniprotkb:Q8K2T8 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-642477|uniprotkb:Q3UY97|uniprotkb:Q9CS63|uniprotkb:Q9JJ99|ensembl:ENSMUSP00000003529 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:paf1_mouse(display_long)|uniprotkb:Paf1(gene name)|psi-mi:Paf1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6261590|imex:IM-17619-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_062331.2|ensembl:ENSMUSG00000003437(gene)|ensembl:ENSMUST00000003529(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8K2T8|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654 - - - figure legend:fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2014/10/16 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:1cFGAVgb19bf33BaPcIowpXT5qc10090 intact-crc:9184A40205C61267|rigid:KNgRIJAZNw7p94PUaeECYnxA5XQ false v5 tag:c-c|biotin tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99J95 uniprotkb:Q9QWV9 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-2655009|uniprotkb:Q9Z0U7|uniprotkb:Q3V0G4|ensembl:ENSMUSP00000012104|ensembl:ENSMUSP00000126874 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:ccnt1_mouse(display_long)|uniprotkb:Ccnt1(gene name)|psi-mi:Ccnt1(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6261590|imex:IM-17619-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N refseq:NP_033963.1|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:Q9QWV9|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|ensembl:ENSMUSG00000011960(gene)|ensembl:ENSMUST00000012104(transcript)|ensembl:ENSMUST00000169707(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated) - - - figure legend:fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2014/10/16 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:0OHMWIM5Vb9/Whq5PdvunZdi1F010090 intact-crc:9184A40205C61267|rigid:KNgRIJAZNw7p94PUaeECYnxA5XQ false v5 tag:c-c|biotin tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99J95 uniprotkb:Q925J9 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-5745083|ensembl:ENSMUSP00000103169|uniprotkb:A2A526|uniprotkb:A2A528|uniprotkb:O88323|uniprotkb:Q3UHV0|uniprotkb:Q6AXD5|uniprotkb:Q8BW37|uniprotkb:Q8BX19|uniprotkb:Q8VDQ7|uniprotkb:Q925K0 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:med1_mouse(display_long)|uniprotkb:Med1(gene name)|psi-mi:Med1(display_short)|uniprotkb:Crsp210(gene name synonym)|uniprotkb:Drip205(gene name synonym)|uniprotkb:Pbp(gene name synonym)|uniprotkb:Pparbp(gene name synonym)|uniprotkb:Trap220(gene name synonym)|uniprotkb:Trip2(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6261590|imex:IM-17619-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000018160(gene)|ensembl:ENSMUST00000107545(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:NP_001073587.1|refseq:NP_038662.2|refseq:NP_598788.2|dip:DIP-59232N|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q925J9|rcsb pdb:1XDK|reactome:R-MMU-212436|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-9018519|reactome:R-MMU-9707564 - - - figure legend:fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2014/10/16 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:U/w8SAVhDt9FGnx+YeK9FyNTjHo10090 intact-crc:9184A40205C61267|rigid:KNgRIJAZNw7p94PUaeECYnxA5XQ false v5 tag:c-c|biotin tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99J95 uniprotkb:Q3TVI4 intact:EBI-2654963|uniprotkb:B0R020|uniprotkb:Q3U002|uniprotkb:Q3UMY2|uniprotkb:Q3UPT3|uniprotkb:Q3UQI6|uniprotkb:Q8BTN0|ensembl:ENSMUSP00000009699 intact:EBI-6261072|ensembl:ENSMUSP00000053678|ensembl:ENSMUSP00000102652|uniprotkb:Q9D4C7 psi-mi:cdk9_mouse(display_long)|uniprotkb:Cdk9(gene name)|psi-mi:Cdk9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym) psi-mi:hexi2_mouse(display_long)|uniprotkb:Hexim2(gene name)|psi-mi:Hexim2(display_short) psi-mi:"MI:0096"(pull down) Bezstarosti et al. (2010) pubmed:20593818|imex:IM-17619 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6261590|imex:IM-17619-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237303.1|refseq:NP_570930.1|ensembl:ENSMUSG00000009555(gene)|ensembl:ENSMUST00000009699(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0017069"(snRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99J95|reactome:R-MMU-112382|reactome:R-MMU-2173796|reactome:R-MMU-674695|reactome:R-MMU-6796648|reactome:R-MMU-6807505|reactome:R-MMU-75955|reactome:R-MMU-9018519|dip:DIP-46368N ensembl:ENSMUSG00000043372(gene)|ensembl:ENSMUST00000062530(transcript)|ensembl:ENSMUST00000107037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|interpro:IPR024872|interpro:IPR024876|refseq:XP_006534291.1|refseq:XP_006534292.1|refseq:XP_006534293.1|refseq:XP_006534294.1|refseq:NP_001123987.1|refseq:NP_001123988.1|refseq:NP_081934.1 - - - figure legend:fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-erythroleukemia)|taxid:10090(Mus musculus) - 2012/08/02 2014/10/16 rogid:slOwv3sib3QkskM1gK+WEtTR3Z410090 rogid:jZd4x7+NPSqTaf2h6vVJDUaS2rk10090 intact-crc:9184A40205C61267|rigid:KNgRIJAZNw7p94PUaeECYnxA5XQ false v5 tag:c-c|biotin tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)