#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P24409	uniprotkb:F1PMM8	intact:EBI-6373207	intact:EBI-6373220|ensembl:ENSCAFP00000001879	psi-mi:rab10_canlf(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	psi-mi:f1pmm8_canlf(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Babbey et al. (2010)	pubmed:20576682	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6373384	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417	ensembl:ENSCAFG00000001308(gene)|ensembl:ENSCAFT00000002031(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005902"(microvillus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|reactome:R-CFA-5620916|refseq:XP_539369.2	-	-	-	figure legend:Fig 5|curation depth:mimix curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2012/10/17	2014/10/16	rogid:8uDakfdQWy3+8DTVQvbZQmRLAyU9615	rogid:X7EEo+UgYDsME/4A5Fq0TrPbJs89615	intact-crc:923C649DAAFAA342|rigid:nydTH3qjEGNe0CA1NiIKIgoclNw	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P24409	uniprotkb:F1PX56	intact:EBI-6373207	intact:EBI-6373231|ensembl:ENSCAFP00000016083	psi-mi:rab10_canlf(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	psi-mi:f1px56_canlf(display_long)|uniprotkb:EXOC3(gene name)|psi-mi:EXOC3(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Babbey et al. (2010)	pubmed:20576682	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6373377	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417	ensembl:ENSCAFG00000010918(gene)|ensembl:ENSCAFT00000017374(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0006887"(exocytosis)|go:"GO:0051601"(exocyst localization)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|reactome:R-CFA-5620916|refseq:XP_848639.1	-	-	-	figure legend:Fig 5|curation depth:mimix curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2012/10/17	2014/10/16	rogid:8uDakfdQWy3+8DTVQvbZQmRLAyU9615	rogid:SwiMBtOMjIEWQ8+Lb9DVr3TE3ug9615	intact-crc:47D3CCE9A20CE715|rigid:5CkWnHz7X9QCijjf9UpzEDb0dBY	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:F1PMM8	uniprotkb:P61026	intact:EBI-6373220|ensembl:ENSCAFP00000001879	intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710	psi-mi:f1pmm8_canlf(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)	psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Babbey et al. (2010)	pubmed:20576682	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6466462	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCAFG00000001308(gene)|ensembl:ENSCAFT00000002031(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005902"(microvillus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|reactome:R-CFA-5620916|refseq:XP_539369.2	refseq:NP_057215.3|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000084733(gene)|ensembl:ENST00000264710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)	-	-	-	figure legend:Fig 6|curation depth:mimix curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2012/10/17	2014/10/16	rogid:X7EEo+UgYDsME/4A5Fq0TrPbJs89615	rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606	intact-crc:E504797E0D22AAEC|rigid:s14UPefRCRYT9FXu4jNnEbE7Icw	false	-	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:F1PMM8	uniprotkb:P24409	intact:EBI-6373220|ensembl:ENSCAFP00000001879	intact:EBI-6373207	psi-mi:f1pmm8_canlf(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)	psi-mi:rab10_canlf(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Babbey et al. (2010)	pubmed:20576682	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6373218	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCAFG00000001308(gene)|ensembl:ENSCAFT00000002031(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005902"(microvillus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|reactome:R-CFA-5620916|refseq:XP_539369.2	go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417	-	-	-	figure legend:Fig 6A|curation depth:mimix curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2012/10/17	2014/10/16	rogid:X7EEo+UgYDsME/4A5Fq0TrPbJs89615	rogid:8uDakfdQWy3+8DTVQvbZQmRLAyU9615	intact-crc:9DF78E9909A3ECCD|rigid:nydTH3qjEGNe0CA1NiIKIgoclNw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P24409	uniprotkb:F1PMM8	intact:EBI-6373207	intact:EBI-6373220|ensembl:ENSCAFP00000001879	psi-mi:rab10_canlf(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short)	psi-mi:f1pmm8_canlf(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Babbey et al. (2010)	pubmed:20576682	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6373388	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417	ensembl:ENSCAFG00000001308(gene)|ensembl:ENSCAFT00000002031(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005902"(microvillus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|reactome:R-CFA-5620916|refseq:XP_539369.2	-	-	-	figure legend:fig 6C|curation depth:mimix curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2012/10/17	2014/10/16	rogid:8uDakfdQWy3+8DTVQvbZQmRLAyU9615	rogid:X7EEo+UgYDsME/4A5Fq0TrPbJs89615	intact-crc:ECEA9FD701D76B83|rigid:nydTH3qjEGNe0CA1NiIKIgoclNw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)