#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O95273 uniprotkb:P55042 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 intact:EBI-3911502|uniprotkb:Q96F39|ensembl:ENSP00000299759|ensembl:ENSP00000388744 psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:rad_human(display_long)|uniprotkb:RRAD(gene name)|psi-mi:RRAD(display_short)|uniprotkb:RAD(gene name synonym)|uniprotkb:RAD1(gene name synonym)|uniprotkb:Ras associated with diabetes(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2010) pubmed:20460530|imex:IM-17266 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-5652527|imex:IM-17266-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5 refseq:NP_001122322.1|refseq:NP_004156.1|ensembl:ENSG00000166592(gene)|ensembl:ENST00000299759(transcript)|ensembl:ENST00000420652(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|interpro:IPR028869|rcsb pdb:2DPX|rcsb pdb:2GJS|rcsb pdb:3Q72|rcsb pdb:3Q7P|rcsb pdb:3Q7Q|reactome:R-HSA-9031628|ensembl:ENSP00000299759|ensembl:ENSP00000388744 - - - figure legend:3A|dataset:Diabetes - Interactions investigated in the context of Diabetes|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/02/29 2014/10/16 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 rogid:YqjKdnFhNGqAtV4zoGvflucSYws9606 intact-crc:78641F2C5257AD87|rigid:oPmx58MxW7HXikxYx6GgC453JUA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O95273 uniprotkb:P55042 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 intact:EBI-3911502|uniprotkb:Q96F39|ensembl:ENSP00000299759|ensembl:ENSP00000388744 psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:rad_human(display_long)|uniprotkb:RRAD(gene name)|psi-mi:RRAD(display_short)|uniprotkb:RAD(gene name synonym)|uniprotkb:RAD1(gene name synonym)|uniprotkb:Ras associated with diabetes(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lee et al. (2010) pubmed:20460530|imex:IM-17266 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-5652543|imex:IM-17266-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5 refseq:NP_001122322.1|refseq:NP_004156.1|ensembl:ENSG00000166592(gene)|ensembl:ENST00000299759(transcript)|ensembl:ENST00000420652(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|interpro:IPR028869|rcsb pdb:2DPX|rcsb pdb:2GJS|rcsb pdb:3Q72|rcsb pdb:3Q7P|rcsb pdb:3Q7Q|reactome:R-HSA-9031628|ensembl:ENSP00000299759|ensembl:ENSP00000388744 - - - figure legend:3B|dataset:Diabetes - Interactions investigated in the context of Diabetes|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/02/29 2014/10/16 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 rogid:YqjKdnFhNGqAtV4zoGvflucSYws9606 intact-crc:F058CFB38BE5B8F9|rigid:oPmx58MxW7HXikxYx6GgC453JUA false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P55042 uniprotkb:O95273 intact:EBI-3911502|uniprotkb:Q96F39|ensembl:ENSP00000299759|ensembl:ENSP00000388744 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 psi-mi:rad_human(display_long)|uniprotkb:RRAD(gene name)|psi-mi:RRAD(display_short)|uniprotkb:RAD(gene name synonym)|uniprotkb:RAD1(gene name synonym)|uniprotkb:Ras associated with diabetes(gene name synonym) psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Lee et al. (2010) pubmed:20460530|imex:IM-17266 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-5652579|imex:IM-17266-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001122322.1|refseq:NP_004156.1|ensembl:ENSG00000166592(gene)|ensembl:ENST00000299759(transcript)|ensembl:ENST00000420652(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|interpro:IPR028869|rcsb pdb:2DPX|rcsb pdb:2GJS|rcsb pdb:3Q72|rcsb pdb:3Q7P|rcsb pdb:3Q7Q|reactome:R-HSA-9031628|ensembl:ENSP00000299759|ensembl:ENSP00000388744 refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5 go:"GO:0005737"(cytoplasm) - - figure legend:3D|dataset:Diabetes - Interactions investigated in the context of Diabetes|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/02/29 2014/10/16 rogid:YqjKdnFhNGqAtV4zoGvflucSYws9606 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 intact-crc:1C08BF91C8625F2D|rigid:oPmx58MxW7HXikxYx6GgC453JUA false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O95273 uniprotkb:P55042 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 intact:EBI-3911502|uniprotkb:Q96F39|ensembl:ENSP00000299759|ensembl:ENSP00000388744 psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:rad_human(display_long)|uniprotkb:RRAD(gene name)|psi-mi:RRAD(display_short)|uniprotkb:RAD(gene name synonym)|uniprotkb:RAD1(gene name synonym)|uniprotkb:Ras associated with diabetes(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2010) pubmed:20460530|imex:IM-17266 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-5652559|imex:IM-17266-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5 refseq:NP_001122322.1|refseq:NP_004156.1|ensembl:ENSG00000166592(gene)|ensembl:ENST00000299759(transcript)|ensembl:ENST00000420652(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|interpro:IPR028869|rcsb pdb:2DPX|rcsb pdb:2GJS|rcsb pdb:3Q72|rcsb pdb:3Q7P|rcsb pdb:3Q7Q|reactome:R-HSA-9031628|ensembl:ENSP00000299759|ensembl:ENSP00000388744 - - - figure legend:3C|dataset:Diabetes - Interactions investigated in the context of Diabetes|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/02/29 2014/10/16 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 rogid:YqjKdnFhNGqAtV4zoGvflucSYws9606 intact-crc:9E5D1282D9C93594|rigid:oPmx58MxW7HXikxYx6GgC453JUA false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P55042 uniprotkb:O95273 intact:EBI-3911502|uniprotkb:Q96F39|ensembl:ENSP00000299759|ensembl:ENSP00000388744 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 psi-mi:rad_human(display_long)|uniprotkb:RRAD(gene name)|psi-mi:RRAD(display_short)|uniprotkb:RAD(gene name synonym)|uniprotkb:RAD1(gene name synonym)|uniprotkb:Ras associated with diabetes(gene name synonym) psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Lee et al. (2010) pubmed:20460530|imex:IM-17266 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-5652609|imex:IM-17266-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001122322.1|refseq:NP_004156.1|ensembl:ENSG00000166592(gene)|ensembl:ENST00000299759(transcript)|ensembl:ENST00000420652(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR017358(GTP-binding, GEM/REM/Rad)|interpro:IPR027417|interpro:IPR028869|rcsb pdb:2DPX|rcsb pdb:2GJS|rcsb pdb:3Q72|rcsb pdb:3Q7P|rcsb pdb:3Q7Q|reactome:R-HSA-9031628|ensembl:ENSP00000299759|ensembl:ENSP00000388744 refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5 go:"GO:0005737"(cytoplasm) - - figure legend:S4|dataset:Diabetes - Interactions investigated in the context of Diabetes|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-pc3)|taxid:9606(Human PC3 Caucasian prostate adenocarcinoma) - 2012/02/29 2014/10/16 rogid:YqjKdnFhNGqAtV4zoGvflucSYws9606 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 intact-crc:8A36B8A778BCCF14|rigid:oPmx58MxW7HXikxYx6GgC453JUA false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)