#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P10443	uniprotkb:P0A988	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-542385|uniprotkb:P00583|uniprotkb:Q2M813|ensemblbacteria:AAC76724|ensemblbacteria:BAE77593	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:dpo3b_ecoli(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:JW3678(locus name)|uniprotkb:b3701(locus name)	psi-mi:"MI:0071"(molecular sieving)	Stukenberg et al. (1991)	pubmed:2040637|imex:IM-18531	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6421185|imex:IM-18531-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	ensemblbacteria:AAC76724(transcript)|ensemblbacteria:b3701(gene)|ensemblbacteria:BAE77593(gene)|ensemblbacteria:BAE77593(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0044787"(bacterial-type DNA replication)|interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022634|interpro:IPR022635|interpro:IPR022637|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1MMI|rcsb pdb:1OK7|rcsb pdb:1UNN|rcsb pdb:1WAI|rcsb pdb:2POL|rcsb pdb:2XUR|rcsb pdb:3BEP|rcsb pdb:3D1E|rcsb pdb:3D1F|rcsb pdb:3D1G|rcsb pdb:3F1V|rcsb pdb:3PWE|rcsb pdb:3Q4J|rcsb pdb:3Q4K|rcsb pdb:3Q4L|rcsb pdb:3QSB|rcsb pdb:4K3K|rcsb pdb:4K3L|rcsb pdb:4K3M|rcsb pdb:4K3O|rcsb pdb:4K3P|rcsb pdb:4K3Q|rcsb pdb:4K3R|rcsb pdb:4K3S|rcsb pdb:4MJP|rcsb pdb:4MJQ|rcsb pdb:4MJR|rcsb pdb:4N94|rcsb pdb:4N95|rcsb pdb:4N96|rcsb pdb:4N97|rcsb pdb:4N98|rcsb pdb:4N99|rcsb pdb:4N9A|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:6E8E|rcsb pdb:6FVL|refseq:NP_418156.1|refseq:WP_000673464.1|dip:DIP-36038N	go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0003677"(DNA binding)|go:"GO:0030894"(replisome)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)	-	caution:This sequence has been withdrawn from Uniprot.	figure legend:Fig. 2c|complex-synonym:DNA polymerase holoenzyme|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/12/03	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:9CWZmgLmO/kNXmVq75u0u04mX2g83333	intact-crc:C004383146A0F1AF|rigid:j7r/iQHztvzTqzwVWDTncIRCNd8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P03007	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-549131|ensemblbacteria:AAC73320|ensemblbacteria:BAA77886	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:dpo3e_ecoli(display_long)|uniprotkb:dnaQ(gene name)|psi-mi:dnaQ(display_short)|uniprotkb:mutD(gene name synonym)|uniprotkb:b0215(locus name)|uniprotkb:JW0205(locus name)	psi-mi:"MI:0071"(molecular sieving)	Stukenberg et al. (1991)	pubmed:2040637|imex:IM-18531	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6421185|imex:IM-18531-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	refseq:NP_414751.1|refseq:WP_001340895.1|dip:DIP-9462N|ensemblbacteria:AAC73320(transcript)|ensemblbacteria:b0215(gene)|ensemblbacteria:BAA77886(gene)|ensemblbacteria:BAA77886(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005829"(cytosol)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|interpro:IPR006054(DNA polymerase III, epsilon subunit)|interpro:IPR006309(DNA polymerase 3, epsilon subunit)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036397|rcsb pdb:1J53|rcsb pdb:1J54|rcsb pdb:1MGZ|rcsb pdb:2GUI|rcsb pdb:2IDO|rcsb pdb:2XY8|rcsb pdb:4GX8|rcsb pdb:4GX9|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S	go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0003677"(DNA binding)|go:"GO:0030894"(replisome)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)	-	-	figure legend:Fig. 2c|complex-synonym:DNA polymerase holoenzyme|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/12/03	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:+Xs56/RcG3EYpWsa57MFJRFspoI83333	intact-crc:C004383146A0F1AF|rigid:j7r/iQHztvzTqzwVWDTncIRCNd8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P0A988	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-542385|uniprotkb:P00583|uniprotkb:Q2M813|ensemblbacteria:AAC76724|ensemblbacteria:BAE77593	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:dpo3b_ecoli(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:JW3678(locus name)|uniprotkb:b3701(locus name)	psi-mi:"MI:0071"(molecular sieving)	Stukenberg et al. (1991)	pubmed:2040637|imex:IM-18531	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6421327|imex:IM-18531-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	ensemblbacteria:AAC76724(transcript)|ensemblbacteria:b3701(gene)|ensemblbacteria:BAE77593(gene)|ensemblbacteria:BAE77593(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0044787"(bacterial-type DNA replication)|interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022634|interpro:IPR022635|interpro:IPR022637|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1MMI|rcsb pdb:1OK7|rcsb pdb:1UNN|rcsb pdb:1WAI|rcsb pdb:2POL|rcsb pdb:2XUR|rcsb pdb:3BEP|rcsb pdb:3D1E|rcsb pdb:3D1F|rcsb pdb:3D1G|rcsb pdb:3F1V|rcsb pdb:3PWE|rcsb pdb:3Q4J|rcsb pdb:3Q4K|rcsb pdb:3Q4L|rcsb pdb:3QSB|rcsb pdb:4K3K|rcsb pdb:4K3L|rcsb pdb:4K3M|rcsb pdb:4K3O|rcsb pdb:4K3P|rcsb pdb:4K3Q|rcsb pdb:4K3R|rcsb pdb:4K3S|rcsb pdb:4MJP|rcsb pdb:4MJQ|rcsb pdb:4MJR|rcsb pdb:4N94|rcsb pdb:4N95|rcsb pdb:4N96|rcsb pdb:4N97|rcsb pdb:4N98|rcsb pdb:4N99|rcsb pdb:4N9A|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:6E8E|rcsb pdb:6FVL|refseq:NP_418156.1|refseq:WP_000673464.1|dip:DIP-36038N	go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0030894"(replisome)|go:"GO:0003677"(DNA binding)	-	caution:This sequence has been withdrawn from Uniprot.	figure legend:Fig. 2d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/12/03	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:9CWZmgLmO/kNXmVq75u0u04mX2g83333	intact-crc:0D5664C16124C928|rigid:jMFDsyGirvNNpCbJ8Z/SfCIZ0r0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)