#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8YC73 uniprotkb:Q2YRB4 intact:EBI-6516062|ensemblbacteria:AAL53901 intact:EBI-6411163|ensemblbacteria:CAJ11577 psi-mi:divk_brume(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)|uniprotkb:BMEII0659(locus name) psi-mi:pdhs_brua2(display_long)|uniprotkb:pdhS(gene name)|psi-mi:pdhS(display_short)|uniprotkb:BAB1_1621(locus name) psi-mi:"MI:0018"(two hybrid) Mignolet et al. (2010) pubmed:20382762|imex:IM-18342 taxid:224914(brume)|taxid:224914("Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)") taxid:359391(brua2)|taxid:359391(brua2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6516106|mpidb:MPIDB-INT-1392|imex:IM-18342-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_002966022.1|ensemblbacteria:AAL53901(transcript)|ensemblbacteria:BMEII0659(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011006(CheY-like)|interpro:IPR001789(Signal transduction response regulator, receiver region) ensemblbacteria:BAB1_1621(gene)|ensemblbacteria:CAJ11577(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR013767(PAS fold)|refseq:WP_002966929.1|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/30 2014/10/16 rogid:srtHWcqzOplskFO+W1SMsxmHAd4224914 rogid:KZUJsOdEWJS+mnP5CvDDAjQ3XSE359391 intact-crc:788D8BEC5ECC5D34|rigid:pSkQyKOsdMeOmujRso2uUmbE63c false - sufficient binding region:611-1035 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8YB50 uniprotkb:Q2YRB4 intact:EBI-6516077|ensemblbacteria:AAL54293 intact:EBI-6411163|ensemblbacteria:CAJ11577 psi-mi:fumc_brume(display_long)|uniprotkb:fumC(gene name)|psi-mi:fumC(display_short)|uniprotkb:Aerobic fumarase(gene name synonym)|uniprotkb:Iron-independent fumarase(gene name synonym)|uniprotkb:BMEII1051(locus name) psi-mi:pdhs_brua2(display_long)|uniprotkb:pdhS(gene name)|psi-mi:pdhS(display_short)|uniprotkb:BAB1_1621(locus name) psi-mi:"MI:0018"(two hybrid) Mignolet et al. (2010) pubmed:20382762|imex:IM-18342 taxid:224914(brume)|taxid:224914("Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)") taxid:359391(brua2)|taxid:359391(brua2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6516104|mpidb:MPIDB-INT-1391|imex:IM-18342-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_002966390.1|ensemblbacteria:AAL54293(transcript)|ensemblbacteria:BMEII1051(gene)|go:"GO:0004333"(fumarate hydratase activity)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|interpro:IPR005677(Fumarate hydratase, class II)|interpro:IPR018951|interpro:IPR000362(Fumarate lyase)|interpro:IPR020557|interpro:IPR008948(L-Aspartase-like)|interpro:IPR024083|interpro:IPR022761 ensemblbacteria:BAB1_1621(gene)|ensemblbacteria:CAJ11577(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR013767(PAS fold)|refseq:WP_002966929.1|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/30 2014/10/16 rogid:wOKki1kd8UDyRitUmuJIpm811Do224914 rogid:KZUJsOdEWJS+mnP5CvDDAjQ3XSE359391 intact-crc:3E0AEC84A5FECD30|rigid:CQfSftMT9qU0a7eAgF1Msxp32po false - sufficient binding region:1-613 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8YC73 uniprotkb:Q2YRB4 intact:EBI-6516062|ensemblbacteria:AAL53901 intact:EBI-6411163|ensemblbacteria:CAJ11577 psi-mi:divk_brume(display_long)|uniprotkb:divK(gene name)|psi-mi:divK(display_short)|uniprotkb:BMEII0659(locus name) psi-mi:pdhs_brua2(display_long)|uniprotkb:pdhS(gene name)|psi-mi:pdhS(display_short)|uniprotkb:BAB1_1621(locus name) psi-mi:"MI:0018"(two hybrid) Mignolet et al. (2010) pubmed:20382762|imex:IM-18342 taxid:224914(brume)|taxid:224914("Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)") taxid:359391(brua2)|taxid:359391(brua2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6411153|mpidb:MPIDB-INT-1392|imex:IM-18342-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_002966022.1|ensemblbacteria:AAL53901(transcript)|ensemblbacteria:BMEII0659(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011006(CheY-like)|interpro:IPR001789(Signal transduction response regulator, receiver region) ensemblbacteria:BAB1_1621(gene)|ensemblbacteria:CAJ11577(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR013767(PAS fold)|refseq:WP_002966929.1|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/30 2014/10/16 rogid:srtHWcqzOplskFO+W1SMsxmHAd4224914 rogid:KZUJsOdEWJS+mnP5CvDDAjQ3XSE359391 intact-crc:E6BB8B7028A4C592|rigid:pSkQyKOsdMeOmujRso2uUmbE63c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8YB50 uniprotkb:Q2YRB4 intact:EBI-6516077|ensemblbacteria:AAL54293 intact:EBI-6411163|ensemblbacteria:CAJ11577 psi-mi:fumc_brume(display_long)|uniprotkb:fumC(gene name)|psi-mi:fumC(display_short)|uniprotkb:Aerobic fumarase(gene name synonym)|uniprotkb:Iron-independent fumarase(gene name synonym)|uniprotkb:BMEII1051(locus name) psi-mi:pdhs_brua2(display_long)|uniprotkb:pdhS(gene name)|psi-mi:pdhS(display_short)|uniprotkb:BAB1_1621(locus name) psi-mi:"MI:0018"(two hybrid) Mignolet et al. (2010) pubmed:20382762|imex:IM-18342 taxid:224914(brume)|taxid:224914("Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)") taxid:359391(brua2)|taxid:359391(brua2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6411181|mpidb:MPIDB-INT-1391|imex:IM-18342-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_002966390.1|ensemblbacteria:AAL54293(transcript)|ensemblbacteria:BMEII1051(gene)|go:"GO:0004333"(fumarate hydratase activity)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|interpro:IPR005677(Fumarate hydratase, class II)|interpro:IPR018951|interpro:IPR000362(Fumarate lyase)|interpro:IPR020557|interpro:IPR008948(L-Aspartase-like)|interpro:IPR024083|interpro:IPR022761 ensemblbacteria:BAB1_1621(gene)|ensemblbacteria:CAJ11577(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR013767(PAS fold)|refseq:WP_002966929.1|interpro:IPR000014(PAS)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/30 2014/10/16 rogid:wOKki1kd8UDyRitUmuJIpm811Do224914 rogid:KZUJsOdEWJS+mnP5CvDDAjQ3XSE359391 intact-crc:8C8E85DDE0C56344|rigid:CQfSftMT9qU0a7eAgF1Msxp32po false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)