#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O76075	uniprotkb:O00273	intact:EBI-1053821|uniprotkb:O60521|uniprotkb:Q9BYI4|uniprotkb:Q9BYI5|uniprotkb:Q9BYI6|uniprotkb:Q5SR22|ensembl:ENSP00000367454	intact:EBI-727171|uniprotkb:Q96I97|uniprotkb:Q9Y6C6|uniprotkb:Q5T6G6|uniprotkb:Q5T6G5|ensembl:ENSP00000366237	psi-mi:dffb_human(display_long)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym)|uniprotkb:DFFB(gene name)|psi-mi:DFFB(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:DFF2(gene name synonym)|uniprotkb:DFF40(gene name synonym)|uniprotkb:Caspase-activated nuclease(gene name synonym)	psi-mi:dffa_human(display_long)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym)|uniprotkb:DFFA(gene name)|psi-mi:DFFA(display_short)|uniprotkb:DFF1(gene name synonym)|uniprotkb:DFF45(gene name synonym)|uniprotkb:H13(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ninios et al. (2010)	pubmed:19882353|imex:IM-17244	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327588|imex:IM-17244-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004393.1|refseq:NP_001307061.1|ensembl:ENSG00000169598(gene)|ensembl:ENST00000378209(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|rcsb pdb:1IBX|reactome:R-HSA-140342	refseq:NP_004392.1|refseq:NP_998731.1|ensembl:ENSG00000160049(gene)|ensembl:ENST00000377038(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1IBX|rcsb pdb:1IYR|rcsb pdb:1KOY|reactome:R-HSA-140342	-	-	-	figure legend:4b|comment:"The interaction decreases upon TSA treatment (induces apoptosis)."|comment:Histone H1 was also identified in this complex but could not be ascribed to a single gene product.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nb4)|taxid:9606(Human NB4 APL cell line)	-	2012/01/18	2014/10/16	rogid:e2mhwP1jJQZACErC+aYXAexfIOk9606	rogid:jz7MT9TaqFl1lwoITptPZ3P2KVY9606	intact-crc:F4E3517BE3F8E8BC|rigid:rsAB7MnNbzCurCUNO0oXUPDi1ws	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O76075	uniprotkb:Q02539	intact:EBI-1053821|uniprotkb:O60521|uniprotkb:Q9BYI4|uniprotkb:Q9BYI5|uniprotkb:Q9BYI6|uniprotkb:Q5SR22|ensembl:ENSP00000367454	intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573	psi-mi:dffb_human(display_long)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym)|uniprotkb:DFFB(gene name)|psi-mi:DFFB(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:DFF2(gene name synonym)|uniprotkb:DFF40(gene name synonym)|uniprotkb:Caspase-activated nuclease(gene name synonym)	psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ninios et al. (2010)	pubmed:19882353|imex:IM-17244	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327604|imex:IM-17244-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004393.1|refseq:NP_001307061.1|ensembl:ENSG00000169598(gene)|ensembl:ENST00000378209(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|rcsb pdb:1IBX|reactome:R-HSA-140342	refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584	go:"GO:0000790"	-	-	figure legend:6a and 7b|comment:"The interaction decreases upon TSA treatment (induces apoptosis)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nb4)|taxid:9606(Human NB4 APL cell line)	-	2012/01/18	2014/10/16	rogid:e2mhwP1jJQZACErC+aYXAexfIOk9606	rogid:4u8P8jFM3onWx43+SxL320urjhk9606	intact-crc:0A681605C7BEC56C|rigid:8m6UJZExnwVnDkdG/lFXIs9R4oI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O76075	uniprotkb:P07305	intact:EBI-1053821|uniprotkb:O60521|uniprotkb:Q9BYI4|uniprotkb:Q9BYI5|uniprotkb:Q9BYI6|uniprotkb:Q5SR22|ensembl:ENSP00000367454	intact:EBI-725224|uniprotkb:Q6FG88|uniprotkb:Q8N6R3|uniprotkb:B4DRD6|uniprotkb:B2R6I0|ensembl:ENSP00000344504	psi-mi:dffb_human(display_long)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym)|uniprotkb:DFFB(gene name)|psi-mi:DFFB(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:DFF2(gene name synonym)|uniprotkb:DFF40(gene name synonym)|uniprotkb:Caspase-activated nuclease(gene name synonym)	psi-mi:h10_human(display_long)|uniprotkb:H1-0(gene name)|psi-mi:H1-0(display_short)|uniprotkb:H1F0(gene name synonym)|uniprotkb:H1FV(gene name synonym)|uniprotkb:Histone H1'(gene name synonym)|uniprotkb:"Histone H1(0)"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ninios et al. (2010)	pubmed:19882353|imex:IM-17244	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327604|imex:IM-17244-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004393.1|refseq:NP_001307061.1|ensembl:ENSG00000169598(gene)|ensembl:ENST00000378209(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|rcsb pdb:1IBX|reactome:R-HSA-140342	refseq:NP_005309.1|ensembl:ENSG00000189060(gene)|ensembl:ENST00000340857(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P07305|rcsb pdb:6HQ1|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6N88|rcsb pdb:6N89|rcsb pdb:7DBP|rcsb pdb:7K5X|reactome:R-HSA-140342|reactome:R-HSA-2559584|dip:DIP-41775N	go:"GO:0000790"	-	-	figure legend:6a and 7b|comment:"The interaction decreases upon TSA treatment (induces apoptosis)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nb4)|taxid:9606(Human NB4 APL cell line)	-	2012/01/18	2014/10/16	rogid:e2mhwP1jJQZACErC+aYXAexfIOk9606	rogid:7ir9Jz/gNZypmWkTopCusDQFEhs9606	intact-crc:0A681605C7BEC56C|rigid:8m6UJZExnwVnDkdG/lFXIs9R4oI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O76075	uniprotkb:P16401	intact:EBI-1053821|uniprotkb:O60521|uniprotkb:Q9BYI4|uniprotkb:Q9BYI5|uniprotkb:Q9BYI6|uniprotkb:Q5SR22|ensembl:ENSP00000367454	intact:EBI-5327611|uniprotkb:Q14529|uniprotkb:Q3MJ42|ensembl:ENSP00000330074	psi-mi:dffb_human(display_long)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym)|uniprotkb:DFFB(gene name)|psi-mi:DFFB(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:DFF2(gene name synonym)|uniprotkb:DFF40(gene name synonym)|uniprotkb:Caspase-activated nuclease(gene name synonym)	psi-mi:h15_human(display_long)|uniprotkb:H1-5(gene name)|psi-mi:H1-5(display_short)|uniprotkb:H1F5(gene name synonym)|uniprotkb:HIST1H1B(gene name synonym)|uniprotkb:Histone H1a(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ninios et al. (2010)	pubmed:19882353|imex:IM-17244	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327604|imex:IM-17244-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004393.1|refseq:NP_001307061.1|ensembl:ENSG00000169598(gene)|ensembl:ENST00000378209(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|rcsb pdb:1IBX|reactome:R-HSA-140342	refseq:NP_005313.1|ensembl:ENSG00000184357(gene)|ensembl:ENST00000331442(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0050821"(protein stabilization)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2FE2|rcsb pdb:2RHI|reactome:R-HSA-140342|reactome:R-HSA-2559584|go:"GO:0000792"(heterochromatin)	go:"GO:0000790"	-	-	figure legend:6a and 7b|comment:"The interaction decreases upon TSA treatment (induces apoptosis)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nb4)|taxid:9606(Human NB4 APL cell line)	-	2012/01/18	2014/10/16	rogid:e2mhwP1jJQZACErC+aYXAexfIOk9606	rogid:b81Z7VA09Na0XXDfR0HtaZmq1g89606	intact-crc:0A681605C7BEC56C|rigid:8m6UJZExnwVnDkdG/lFXIs9R4oI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O76075	uniprotkb:P16402	intact:EBI-1053821|uniprotkb:O60521|uniprotkb:Q9BYI4|uniprotkb:Q9BYI5|uniprotkb:Q9BYI6|uniprotkb:Q5SR22|ensembl:ENSP00000367454	intact:EBI-1052479|uniprotkb:Q2M2I2|uniprotkb:B2R751|ensembl:ENSP00000244534	psi-mi:dffb_human(display_long)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym)|uniprotkb:DFFB(gene name)|psi-mi:DFFB(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:DFF2(gene name synonym)|uniprotkb:DFF40(gene name synonym)|uniprotkb:Caspase-activated nuclease(gene name synonym)	psi-mi:h13_human(display_long)|uniprotkb:H1-3(gene name)|psi-mi:H1-3(display_short)|uniprotkb:H1F3(gene name synonym)|uniprotkb:HIST1H1D(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1s-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ninios et al. (2010)	pubmed:19882353|imex:IM-17244	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5327604|imex:IM-17244-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004393.1|refseq:NP_001307061.1|ensembl:ENSG00000169598(gene)|ensembl:ENST00000378209(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|rcsb pdb:1IBX|reactome:R-HSA-140342	refseq:NP_005311.1|ensembl:ENSG00000124575(gene)|ensembl:ENST00000244534(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16402|reactome:R-HSA-140342|reactome:R-HSA-2559584	go:"GO:0000790"	-	-	figure legend:6a and 7b|comment:"The interaction decreases upon TSA treatment (induces apoptosis)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nb4)|taxid:9606(Human NB4 APL cell line)	-	2012/01/18	2014/10/16	rogid:e2mhwP1jJQZACErC+aYXAexfIOk9606	rogid:EKx3L/uC7g4QkB/3ARuTL97tMbw9606	intact-crc:0A681605C7BEC56C|rigid:8m6UJZExnwVnDkdG/lFXIs9R4oI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)