#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8R4A3	uniprotkb:Q60838	intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943	intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362	psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym)	psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Suriben et al. (2009)	pubmed:19701191|imex:IM-17313	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6123910|imex:IM-17313-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258	refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N	-	-	-	figure legend:5e and g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/05/08	2014/10/16	rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090	rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090	intact-crc:1070AD64AE742989|rigid:dwjGglLyLmmr7eN5/nSHB9OXrjM	false	necessary binding region:312-400|flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8R4A3	uniprotkb:Q60838	intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943	intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362	psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym)	psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Suriben et al. (2009)	pubmed:19701191|imex:IM-17313	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6123926|imex:IM-17313-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258	refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N	-	-	-	figure legend:5i|comment:Combined deletion of  Dvl2 160-232 and 265-352 shows a weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/05/08	2014/10/16	rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090	rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090	intact-crc:1FF6EAF7A9CC8867|rigid:dwjGglLyLmmr7eN5/nSHB9OXrjM	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8R4A3	uniprotkb:Q91ZD4	intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943	intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894	psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym)	psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Suriben et al. (2009)	pubmed:19701191|imex:IM-17313	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6123882|imex:IM-17313-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258	refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273	-	-	-	figure legend:5d and f|comment:Deletion of Dact1 691-750 shows a weak interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/05/08	2014/10/16	rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090	rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090	intact-crc:3BF033E1CE660A3B|rigid:yTcOG1pSd34vinJpB51F5HcKQkg	false	flag tag:?-?|necessary binding region:529-690	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q91ZD4	uniprotkb:Q60838	intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894	intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362	psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym)	psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Suriben et al. (2009)	pubmed:19701191|imex:IM-17313	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6123941|imex:IM-17313-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273	refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N	-	-	-	figure legend:5h|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/05/08	2014/10/16	rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090	rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090	intact-crc:8E670A4D9BD5A09D|rigid:jx1iU9MN+ayPpSgFPYOapTqvTr0	false	-	necessary binding region:160-352|ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8R4A3	uniprotkb:Q91ZD4	intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943	intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894	psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym)	psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Suriben et al. (2009)	pubmed:19701191|imex:IM-17313	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6123960|imex:IM-17313-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258	refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273	-	-	-	figure legend:5j|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/08	2014/10/16	rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090	rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090	intact-crc:A414970AE07C23D4|rigid:yTcOG1pSd34vinJpB51F5HcKQkg	false	sufficient binding region:444-778|glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q91ZD4	uniprotkb:P09803	intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894	intact:EBI-984420|uniprotkb:Q61377	psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym)	psi-mi:cadh1_mouse(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:ARC-1(gene name synonym)|uniprotkb:Cdh1(gene name)|psi-mi:Cdh1(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Suriben et al. (2009)	pubmed:19701191|imex:IM-17313	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6124025|imex:IM-17313-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273	go:"GO:0001701"(in utero embryonic development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0007566"(embryo implantation)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0019538"(protein metabolic process)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033561"(regulation of water loss via skin)|go:"GO:0034332"(adherens junction organization)|go:"GO:0035847"(uterine epithelium development)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0090102"(cochlea development)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043296"(apical junction complex)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|go:"GO:0043679"(axon terminus)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0060693"(regulation of branching involved in salivary gland morphogenesis)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|rcsb pdb:1EDH|rcsb pdb:1FF5|rcsb pdb:1I7W|rcsb pdb:1I7X|rcsb pdb:1Q1P|rcsb pdb:1SUH|rcsb pdb:2OMW|rcsb pdb:2QVF|rcsb pdb:3IFQ|rcsb pdb:3LNE|interpro:IPR015919(Cadherin-like)|rcsb pdb:3LNF|rcsb pdb:3LNG|rcsb pdb:3LNH|rcsb pdb:3LNI|rcsb pdb:3Q2L|rcsb pdb:3Q2N|rcsb pdb:3Q2V|rcsb pdb:3QRB|rcsb pdb:4QD2|rcsb pdb:7AR4|reactome:R-MMU-1474228|reactome:R-MMU-216083|reactome:R-MMU-351906|reactome:R-MMU-418990|reactome:R-MMU-5626467|refseq:NP_033994.1|dip:DIP-29635N|mint:P09803	go:"GO:0009986"(cell surface)	-	-	figure legend:6g|comment:"Partial colocalization shown in all germ layers of the primitive streak (epithelial cells of ectoderm and endodem, and mesenchymal cells)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryo)|taxid:10090(Mus musculus embryo)	-	2012/05/08	2014/10/16	rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090	rogid:VC5bbvNrxRzOFvwFCr/+CS2cSG410090	intact-crc:0DA3A11CE0C69A52|rigid:vjkAN80l1w2uBguYo7dvWWRsKA4	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)