#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P07339 uniprotkb:P13128 intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671 intact:EBI-6407357|ensemblbacteria:CAD00729|uniprotkb:Q57096|uniprotkb:Q48747|uniprotkb:Q57206 psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym) psi-mi:tacy_lismo(display_long)|uniprotkb:LLO(gene name synonym)|uniprotkb:Thiol-activated cytolysin(gene name synonym)|uniprotkb:hlyA(gene name synonym)|uniprotkb:lisA(gene name synonym)|uniprotkb:lmo0202(locus name)|uniprotkb:hly(gene name)|psi-mi:hly(display_short) psi-mi:"MI:0435"(protease assay) Carrasco-MarĂ­n et al. (2009) pubmed:19389128|imex:IM-18278 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:169963(lismo)|taxid:169963("Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)") psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0903"(mpidb) intact:EBI-6407373|mpidb:MPIDB-INT-1060|imex:IM-18278-2 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001900.1|dip:DIP-43906N|ensembl:ENSG00000117984(gene)|ensembl:ENST00000236671(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-9018519 ensemblbacteria:CAD00729(gene)|ensemblbacteria:CAD00729(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR001869(Thiol-activated cytolysin)|refseq:NP_463733.1|rcsb pdb:4CDB|refseq:WP_003722731.1|interpro:IPR038700|interpro:IPR035390|interpro:IPR036359|interpro:IPR036363 - - - figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/30 2014/10/16 rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606 rogid:Bv3sXK/HZ4zkspJHx2Zm1tjCCUg169963 intact-crc:BDEF1D0C01E4CB5F|rigid:CwNO9XQTKw91uuem4aRIb4Gam3U false - his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)