#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P09184	uniprotkb:P23367	intact:EBI-765033|ensemblbacteria:AAC75026|ensemblbacteria:BAA15787	intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171	psi-mi:vsr_ecoli(display_long)|uniprotkb:DNA mismatch endonuclease(gene name synonym)|uniprotkb:Vsr mismatch endonuclease(gene name synonym)|uniprotkb:V.EcoKDcm(gene name synonym)|uniprotkb:vsr(gene name)|psi-mi:vsr(display_short)|uniprotkb:b1960(locus name)|uniprotkb:JW1943(locus name)	psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Polosina et al. (2009)	pubmed:19376855|imex:IM-18277	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6407336|mpidb:MPIDB-INT-707|imex:IM-18277-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416469.1|refseq:WP_000786005.1|dip:DIP-11114N|ensemblbacteria:AAC75026(transcript)|ensemblbacteria:b1960(gene)|ensemblbacteria:BAA15787(gene)|ensemblbacteria:BAA15787(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0043765"(T/G mismatch-specific endonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|rcsb pdb:1CW0|rcsb pdb:1ODG|rcsb pdb:1VSR|interpro:IPR004603(DNA mismatch endonuclease vsr)	refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC	-	-	-	figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/11/30	2014/10/16	rogid:2a0R+aMcWPpCj/cSQ9UvaJS+Qao83333	rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333	intact-crc:D525F1395DEB1900|rigid:yUJT0m36qKgzG64c9M+SbQxYqc8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23367	uniprotkb:P06722	intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171	intact:EBI-545170|uniprotkb:Q2MA06|uniprotkb:Q9R2X2|uniprotkb:Q9R3A8|uniprotkb:Q9R411|uniprotkb:Q9S6P5|uniprotkb:Q9S6P6|uniprotkb:Q9S6P7|ensemblbacteria:AAC75870|ensemblbacteria:BAE76900	psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name)	psi-mi:muth_ecoli(display_long)|uniprotkb:mutH(gene name)|psi-mi:mutH(display_short)|uniprotkb:mutR(gene name synonym)|uniprotkb:prv(gene name synonym)|uniprotkb:b2831(locus name)|uniprotkb:Methyl-directed mismatch repair protein(gene name synonym)|uniprotkb:JW2799(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Polosina et al. (2009)	pubmed:19376855|imex:IM-18277	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6407331|mpidb:MPIDB-INT-708|imex:IM-18277-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC	go:"GO:0000018"(regulation of DNA recombination)|ensemblbacteria:BAE76900(transcript)|ensemblbacteria:AAC75870(transcript)|ensemblbacteria:b2831(gene)|ensemblbacteria:BAE76900(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0006304"(DNA modification)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0043765"(T/G mismatch-specific endonuclease activity)|interpro:IPR004230(DNA mismatch repair protein MutH)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011337(Restriction endonuclease, type II, EcoRV-like/DNA mismatch repair MutH, core)|interpro:IPR037057|rcsb pdb:1AZO|rcsb pdb:2AZO|go:"GO:0003677"(DNA binding)|refseq:NP_417308.1|refseq:WP_000082201.1|dip:DIP-10284N	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/11/30	2014/10/16	rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333	rogid:ImnYkXur2U4xVdz5PVvprq8Zgd483333	intact-crc:D2C693D635A27EE6|rigid:1gV7goLXeCXg0TLAfsnNcwP8LGE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23367	uniprotkb:P23367	intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171	intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171	psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name)	psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Polosina et al. (2009)	pubmed:19376855|imex:IM-18277	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6407326|mpidb:MPIDB-INT-709|imex:IM-18277-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC	refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC	-	-	-	figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/11/30	2014/10/16	rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333	rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333	intact-crc:911E4183A1B2A9A6|rigid:Ha3JrkX3/DlzQH8+roGS7gZxKNU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23909	uniprotkb:P23367	intact:EBI-554920|uniprotkb:P71279|uniprotkb:Q2MA96|ensemblbacteria:AAC75775|ensemblbacteria:BAE76810	intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171	psi-mi:muts_ecoli(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:fdv(gene name synonym)|uniprotkb:b2733(locus name)|uniprotkb:JW2703(locus name)	psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Polosina et al. (2009)	pubmed:19376855|imex:IM-18277	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6407341|mpidb:MPIDB-INT-706|imex:IM-18277-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417213.1|refseq:WP_001272928.1|dip:DIP-10287N|ensemblbacteria:AAC75775(transcript)|ensemblbacteria:b2733(gene)|ensemblbacteria:BAE76810(gene)|ensemblbacteria:BAE76810(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032136"(adenine/cytosine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|rcsb pdb:1E3M|rcsb pdb:1NG9|rcsb pdb:1OH5|rcsb pdb:1OH6|rcsb pdb:1OH7|rcsb pdb:1OH8|rcsb pdb:1W7A|rcsb pdb:1WB9|rcsb pdb:1WBB|rcsb pdb:1WBD|rcsb pdb:2OK2|rcsb pdb:2WTU|rcsb pdb:3K0S|rcsb pdb:3ZLJ|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6I5F|rcsb pdb:7AI6|rcsb pdb:7AI7|rcsb pdb:7AIB|rcsb pdb:7AIC	refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC	-	-	-	figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/11/30	2014/10/16	rogid:dATh7ZKvCBDCX9StM+kqKD3kZ+w83333	rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333	intact-crc:C22877CF7DF20DBB|rigid:HePQPhJm5qobtDJhBHOtw/J9ySY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)