#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UQB8	uniprotkb:Q14678-2	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338	intact:EBI-6173812|ensembl:ENSP00000371730	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)	psi-mi:q14678-2(display_long)|uniprotkb:Kank-S(isoform synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189597|imex:IM-17389-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)	ensembl:ENSG00000107104(gene)|ensembl:ENST00000382293(transcript)|intact:EBI-2556221(isoform-parent)	-	-	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-vmrc-rcw)|taxid:9606(Homo sapiens renal cell carcinoma cell line VMRC-RCW)	-	2012/07/11	2014/10/16	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	rogid:15AYPvOkuH9ucUBDepv/WJ8WQgw9606	intact-crc:260AEC4509C81132|rigid:PaoyfVtblvjQbw5050PO+O4/vzY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UQB8	uniprotkb:Q14678-1	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338	intact:EBI-6189601|ensembl:ENSP00000501167|ensembl:ENSP00000477725|ensembl:ENSP00000371734|ensembl:ENSP00000371740	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)	psi-mi:q14678-1(display_long)|uniprotkb:Kank-L(isoform synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189597|imex:IM-17389-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)	ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|ensembl:ENSG00000107104(gene)|intact:EBI-2556221(isoform-parent)	-	-	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-vmrc-rcw)|taxid:9606(Homo sapiens renal cell carcinoma cell line VMRC-RCW)	-	2012/07/11	2014/10/16	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	intact-crc:260AEC4509C81132|rigid:PaoyfVtblvjQbw5050PO+O4/vzY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14678	uniprotkb:Q9UQB8	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189593|imex:IM-17389-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)	-	-	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-vmrc-rcw)|taxid:9606(Homo sapiens renal cell carcinoma cell line VMRC-RCW)	-	2012/07/11	2014/10/16	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	intact-crc:8BBF392199BD8621|rigid:fs2G3uFUeQzmzQ8nxHaEeEQ5UVY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14678	uniprotkb:Q9UQB8	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189624|imex:IM-17389-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)	go:"GO:0071944"(cell periphery)	-	-	figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-vmrc-rcw)|taxid:9606(Homo sapiens renal cell carcinoma cell line VMRC-RCW)	-	2012/07/11	2014/10/16	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	intact-crc:0D17389C7DA83965|rigid:fs2G3uFUeQzmzQ8nxHaEeEQ5UVY	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9Y6W5	uniprotkb:Q14678	intact:EBI-4290615|uniprotkb:O60794|uniprotkb:Q9UDY7|intact:EBI-28973998|ensembl:ENSP00000483313|uniprotkb:B4DZN0	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	psi-mi:wasf2_human(display_long)|uniprotkb:WASF2(gene name)|psi-mi:WASF2(display_short)|uniprotkb:WAVE2(gene name synonym)|uniprotkb:Protein WAVE-2(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 2(gene name synonym)	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189739|imex:IM-17389-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008921.1|ensembl:ENST00000536657|ensembl:ENSP00000439883|ensembl:ENSP00000483313|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q9Y6W5|rcsb pdb:2A40|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|ensembl:ENSG00000158195(gene)|ensembl:ENST00000618852(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031209"(SCAR complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|refseq:NP_001188333.1|dip:DIP-41817N	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	go:"GO:0071944"(cell periphery)	-	-	figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-vmrc-rcw)|taxid:9606(Homo sapiens renal cell carcinoma cell line VMRC-RCW)	-	2012/07/11	2014/10/16	rogid:lRPT4syjPdKz2JoqWQQm3xw4hWc9606	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	intact-crc:C210D3DBDE7EE744|rigid:SXPYYUUyTa6WiHu5pLHFsFNgpnA	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q14678-2	uniprotkb:Q9UQB8-4	intact:EBI-6173812|ensembl:ENSP00000371730	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:q14678-2(display_long)|uniprotkb:Kank-S(isoform synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189646|imex:IM-17389-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107104(gene)|ensembl:ENST00000382293(transcript)|intact:EBI-2556221(isoform-parent)	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	-	-	-	figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/11	2014/10/16	rogid:15AYPvOkuH9ucUBDepv/WJ8WQgw9606	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	intact-crc:1E556EBE97CBB4CA|rigid:Bj4dBweF6uOIVgsZ9diLJZ7BbgI	false	flag tag:n-n|necessary binding region:133-309	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q14678-2	uniprotkb:Q9UQB8-4	intact:EBI-6173812|ensembl:ENSP00000371730	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:q14678-2(display_long)|uniprotkb:Kank-S(isoform synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189636|imex:IM-17389-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107104(gene)|ensembl:ENST00000382293(transcript)|intact:EBI-2556221(isoform-parent)	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	-	-	-	figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/11	2014/10/16	rogid:15AYPvOkuH9ucUBDepv/WJ8WQgw9606	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	intact-crc:DF566201DDDFA946|rigid:Bj4dBweF6uOIVgsZ9diLJZ7BbgI	false	flag tag:n-n	green fluorescent protein tag:n-n|necessary binding region:81-149	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q14678-2	uniprotkb:Q9UQB8-4	intact:EBI-6173812|ensembl:ENSP00000371730	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:q14678-2(display_long)|uniprotkb:Kank-S(isoform synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189658|imex:IM-17389-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107104(gene)|ensembl:ENST00000382293(transcript)|intact:EBI-2556221(isoform-parent)	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	-	-	-	figure legend:2E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/11	2014/10/16	rogid:15AYPvOkuH9ucUBDepv/WJ8WQgw9606	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	intact-crc:DF527201DDDFA946|rigid:Bj4dBweF6uOIVgsZ9diLJZ7BbgI	false	sufficient binding region:133-309|green fluorescent protein tag:n-n	flag tag:n-n|sufficient binding region:1-374	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UQB8-4	uniprotkb:Q14678-2	intact:EBI-6174091|ensembl:ENSP00000315685	intact:EBI-6173812|ensembl:ENSP00000371730	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:q14678-2(display_long)|uniprotkb:Kank-S(isoform synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189670|imex:IM-17389-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	ensembl:ENSG00000107104(gene)|ensembl:ENST00000382293(transcript)|intact:EBI-2556221(isoform-parent)	-	-	-	figure legend:2E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/11	2014/10/16	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	rogid:15AYPvOkuH9ucUBDepv/WJ8WQgw9606	intact-crc:3F2BC10F712140EB|rigid:Bj4dBweF6uOIVgsZ9diLJZ7BbgI	false	sufficient binding region:1-374|flag tag:n-n	green fluorescent protein tag:n-n|sufficient binding region:133-309	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P60953	uniprotkb:Q9UQB8-4	intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|uniprotkb:Q9UDI2|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189725|imex:IM-17389-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0005886"(plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0031996"(thioesterase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|dip:DIP-31097N|reactome:R-HSA-983231|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1AN0|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|rcsb pdb:1A4R|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	-	-	-	figure legend:3A|antagonist:"KANK1 (AC Q14678)  coiled coil region"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/11	2014/10/16	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	intact-crc:73F81F7743E64BBF|rigid:onUjDF1Cs5Lb5Oxirv0x565ws3A	false	mutation:12-12|his tag:?-?	sufficient binding region:1-374|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P63000	uniprotkb:Q9UQB8-4	intact:EBI-413628|ensembl:ENSP00000258737|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q5JAA8|uniprotkb:Q9BTB4	intact:EBI-6174091|ensembl:ENSP00000315685	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	psi-mi:q9uqb8-4(display_long)|uniprotkb:BAIAP2-alpha(isoform synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189690|imex:IM-17389-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006954"(inflammatory response)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|reactome:R-HSA-2424491|refseq:NP_008839.2|refseq:NP_061485.1|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-389359|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-983231|reactome:R-HSA-2871796|reactome:R-HSA-376172|dip:DIP-29260N	ensembl:ENSG00000175866(gene)|ensembl:ENST00000321280(transcript)|intact:EBI-525456(isoform-parent)	-	-	-	figure legend:3A and S1|antagonist:"KANK1 (AC Q14678)  coiled coil region"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/11	2014/10/16	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	rogid:1ytLrQtdXovULW1Ct9t/QxCqnA09606	intact-crc:03EF447DDB075327|rigid:obRApUdTA9U33N0YW9GsW8DU044	false	his tag:?-?|mutation:12-12	mutation disrupting interaction:11-11,143-143|glutathione s tranferase tag:n-n|sufficient binding region:1-374	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14678	uniprotkb:Q9UQB8	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)	psi-mi:"MI:0018"(two hybrid)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189764|imex:IM-17389-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)	-	-	-	figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/07/11	2014/10/16	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	intact-crc:74909D5B8D581111|rigid:fs2G3uFUeQzmzQ8nxHaEeEQ5UVY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14678	uniprotkb:Q9UQB8	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)	psi-mi:"MI:0018"(two hybrid)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189751|imex:IM-17389-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)	-	-	-	figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/07/11	2014/10/16	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	intact-crc:B89C926122F8BA2B|rigid:fs2G3uFUeQzmzQ8nxHaEeEQ5UVY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UQB8	uniprotkb:Q14678	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189777|imex:IM-17389-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	-	-	-	figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/11	2014/10/16	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	intact-crc:A990BEA099A6F4AF|rigid:Q024x9ELFyqKwC5iVQY/nghOTR0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UQB8	uniprotkb:P63000	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338	intact:EBI-413628|ensembl:ENSP00000258737|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q5JAA8|uniprotkb:Q9BTB4	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6189777|imex:IM-17389-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)	ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006954"(inflammatory response)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|reactome:R-HSA-2424491|refseq:NP_008839.2|refseq:NP_061485.1|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-389359|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-983231|reactome:R-HSA-2871796|reactome:R-HSA-376172|dip:DIP-29260N	-	-	-	figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/11	2014/10/16	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	intact-crc:A990BEA099A6F4AF|rigid:Q024x9ELFyqKwC5iVQY/nghOTR0	false	-	mutation:12-12	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P60709	uniprotkb:Q9UQB8	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6192349|imex:IM-17389-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N	refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)	-	-	-	figure legend:S5|antagonist:"KANK1 (AC Q14678)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/11	2014/10/16	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	intact-crc:8300C9F3FF45BC1E|rigid:pjOGcQz3pG+zQ15RwoUwYPiK2wQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UQB8	uniprotkb:Q14678	intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338	intact:EBI-2556221|uniprotkb:Q8IY65|uniprotkb:Q8WX74|uniprotkb:Q5W0W0|uniprotkb:D3DRH3|ensembl:ENSP00000501167|ensembl:ENSP00000371734|ensembl:ENSP00000371740|ensembl:ENSP00000477725|uniprotkb:A2A2W8	psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short)	psi-mi:kank1_human(display_long)|uniprotkb:ANKRD15(gene name synonym)|uniprotkb:KANK(gene name synonym)|uniprotkb:KIAA0172(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 15(gene name synonym)|uniprotkb:Kidney ankyrin repeat-containing protein(gene name synonym)|uniprotkb:KANK1(gene name)|psi-mi:KANK1(display_short)	psi-mi:"MI:0096"(pull down)	Roy et al. (2009)	pubmed:19171758|imex:IM-17389	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6192326|imex:IM-17389-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)	dip:DIP-56491N|refseq:NP_055973.2|ensembl:ENST00000382297(transcript)|ensembl:ENST00000382303(transcript)|ensembl:ENST00000619269(transcript)|ensembl:ENST00000674102(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|rcsb pdb:5YBJ|rcsb pdb:5YBU|reactome:R-HSA-9018519|reactome:R-HSA-9673768|ensembl:ENSG00000107104(gene)|refseq:NP_001243805.1|refseq:NP_001243806.1|refseq:XP_016870003.1|refseq:XP_016870004.1|refseq:XP_016870016.1|refseq:XP_016870017.1|refseq:XP_016870018.1|refseq:XP_016870019.1|refseq:NP_694856.1	-	-	-	figure legend:S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/11	2014/10/16	rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606	rogid:+TXNlWTBf1g8b+TpaR9KiM9f+b89606	intact-crc:40F65620CF52C742|rigid:fs2G3uFUeQzmzQ8nxHaEeEQ5UVY	false	sufficient binding region:1-374|glutathione s tranferase tag:n-n	maltose binding protein tag:?-?|sufficient binding region:133-309	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)