#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P48356-1 uniprotkb:Q8NFJ9 intact:EBI-6143588|ensembl:ENSMUSP00000037385 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 psi-mi:p48356-1(display_long)|uniprotkb:Lepr(gene name)|psi-mi:Lepr(display_short)|uniprotkb:Db(gene name synonym)|uniprotkb:Obr(gene name synonym)|uniprotkb:B219(gene name synonym)|uniprotkb:OB receptor(gene name synonym) psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Seo et al. (2009) imex:IM-17356|pubmed:19150989 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6143587|imex:IM-17356-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2257257(isoform-parent)|ensembl:ENSMUSG00000057722(gene)|ensembl:ENSMUST00000037552(transcript) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 - - - figure legend:Fig 5A|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/06/11 2014/10/16 rogid:jHA91jK8nehmfp3KPNSF/7QoMPs10090 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 intact-crc:3CBEA8255164CD14|rigid:xXwrB5dE0CEbT1K7LWruGtcaDyU false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NFJ9 uniprotkb:P48356-1 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 intact:EBI-6143588|ensembl:ENSMUSP00000037385 psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:p48356-1(display_long)|uniprotkb:Lepr(gene name)|psi-mi:Lepr(display_short)|uniprotkb:Db(gene name synonym)|uniprotkb:Obr(gene name synonym)|uniprotkb:B219(gene name synonym)|uniprotkb:OB receptor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Seo et al. (2009) imex:IM-17356|pubmed:19150989 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6143605|imex:IM-17356-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 intact:EBI-2257257(isoform-parent)|ensembl:ENSMUSG00000057722(gene)|ensembl:ENSMUST00000037552(transcript) intact:EBI-6161248(see-also) - - figure legend:Fig 5B/C/D|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/06/11 2014/10/16 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 rogid:jHA91jK8nehmfp3KPNSF/7QoMPs10090 intact-crc:A1289E1F370D20DC|rigid:xXwrB5dE0CEbT1K7LWruGtcaDyU false myc tag:?-?|mutation decreasing interaction:390-390 flag tag:?-?|sufficient binding region:861..861-1162..1162 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P48356-1 uniprotkb:Q8NFJ9 intact:EBI-6143588|ensembl:ENSMUSP00000037385 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 psi-mi:p48356-1(display_long)|uniprotkb:Lepr(gene name)|psi-mi:Lepr(display_short)|uniprotkb:Db(gene name synonym)|uniprotkb:Obr(gene name synonym)|uniprotkb:B219(gene name synonym)|uniprotkb:OB receptor(gene name synonym) psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Seo et al. (2009) imex:IM-17356|pubmed:19150989 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6143646|imex:IM-17356-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2257257(isoform-parent)|ensembl:ENSMUSG00000057722(gene)|ensembl:ENSMUST00000037552(transcript) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 go:"GO:0005737"(cytoplasm) - - figure legend:Fig S2|comment:co-transfection of LepRb with BBS1-restricted BBS1 localization to small punctuates.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-arpe_19)|taxid:9606(Homo sapiens retinal pigment epithelial cell line ARPE-19) - 2012/06/11 2014/10/16 rogid:jHA91jK8nehmfp3KPNSF/7QoMPs10090 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 intact-crc:AE48B2174502DAFF|rigid:xXwrB5dE0CEbT1K7LWruGtcaDyU false green fluorescent protein tag:?-? red fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)