#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y6D6 uniprotkb:Q7Z4S6 intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215 intact:EBI-2691397|intact:EBI-11051686|uniprotkb:Q9C0F5|uniprotkb:Q9Y590|uniprotkb:Q86WZ5|uniprotkb:Q8IVZ8|uniprotkb:Q9NXU4|uniprotkb:B0I1R9|uniprotkb:A8MX28|uniprotkb:Q7Z668|uniprotkb:Q6UKL9|uniprotkb:B9EGE4|uniprotkb:F5H0C3|uniprotkb:F5H219|uniprotkb:Q2UVF1|intact:EBI-28975118|ensembl:ENSP00000354878 psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym) psi-mi:ki21a_human(display_long)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shen et al. (2008) pubmed:19020088|imex:IM-17496 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6251652|imex:IM-17496-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N ensembl:ENSP00000354878|ensembl:ENST00000361961|ensembl:ENSP00000354851|ensembl:ENST00000541463|ensembl:ENSP00000438075|ensembl:ENST00000544797|ensembl:ENSP00000445606|refseq:NP_001166934.1|refseq:NP_001166935.1|refseq:NP_001166936.1|refseq:NP_060111.2|refseq:XP_005269064.1|refseq:XP_005269070.1|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:1990939"|interpro:IPR001680(WD40 repeat)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036322|interpro:IPR036961|rcsb pdb:5D3A|rcsb pdb:5NFD|rcsb pdb:5YBU|rcsb pdb:5YBV|rcsb pdb:7KLJ|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-56253N - - - figure legend:2A and 4C, D|agonist:"ARF1 (constitutive active) overexpression"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/07/23 2014/10/16 rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606 rogid:GRF+n9Srey50s4v6s2Z2E23/x0s9606 intact-crc:867FBE4422A819E9|rigid:JBEPYE0Jb2N/rW6tnplYvRITvkM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z4S6-2 uniprotkb:Q9Y6D6 intact:EBI-6251716|ensembl:ENSP00000354851 intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215 psi-mi:q7z4s6-2(display_long)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym) psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2008) pubmed:19020088|imex:IM-17496 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6251731|imex:IM-17496-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2691397(isoform-parent)|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361961(transcript)|uniprotkb:Q7Z4S6-2(isoform-parent) ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N - - - figure legend:2B and 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/07/23 2014/10/16 rogid:PxCZv8C7N5DQYJzOD0vEASHh8mU9606 rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606 intact-crc:62E0CBB0290C7E2D|rigid:7lNDrl514CWAkas+R7UsvlTl0c0 false ha tag:?-?|necessary binding region:999-1661 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y6D6 uniprotkb:Q7Z4S6 intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215 intact:EBI-2691397|intact:EBI-11051686|uniprotkb:Q9C0F5|uniprotkb:Q9Y590|uniprotkb:Q86WZ5|uniprotkb:Q8IVZ8|uniprotkb:Q9NXU4|uniprotkb:B0I1R9|uniprotkb:A8MX28|uniprotkb:Q7Z668|uniprotkb:Q6UKL9|uniprotkb:B9EGE4|uniprotkb:F5H0C3|uniprotkb:F5H219|uniprotkb:Q2UVF1|intact:EBI-28975118|ensembl:ENSP00000354878 psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym) psi-mi:ki21a_human(display_long)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short) psi-mi:"MI:0071"(molecular sieving) Shen et al. (2008) pubmed:19020088|imex:IM-17496 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6251694|imex:IM-17496-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N ensembl:ENSP00000354878|ensembl:ENST00000361961|ensembl:ENSP00000354851|ensembl:ENST00000541463|ensembl:ENSP00000438075|ensembl:ENST00000544797|ensembl:ENSP00000445606|refseq:NP_001166934.1|refseq:NP_001166935.1|refseq:NP_001166936.1|refseq:NP_060111.2|refseq:XP_005269064.1|refseq:XP_005269070.1|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:1990939"|interpro:IPR001680(WD40 repeat)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036322|interpro:IPR036961|rcsb pdb:5D3A|rcsb pdb:5NFD|rcsb pdb:5YBU|rcsb pdb:5YBV|rcsb pdb:7KLJ|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-56253N - - - figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2012/07/23 2014/10/16 rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606 rogid:GRF+n9Srey50s4v6s2Z2E23/x0s9606 intact-crc:806C31023C808D9A|rigid:JBEPYE0Jb2N/rW6tnplYvRITvkM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z4S6 uniprotkb:Q9Y6D6 intact:EBI-2691397|intact:EBI-11051686|uniprotkb:Q9C0F5|uniprotkb:Q9Y590|uniprotkb:Q86WZ5|uniprotkb:Q8IVZ8|uniprotkb:Q9NXU4|uniprotkb:B0I1R9|uniprotkb:A8MX28|uniprotkb:Q7Z668|uniprotkb:Q6UKL9|uniprotkb:B9EGE4|uniprotkb:F5H0C3|uniprotkb:F5H219|uniprotkb:Q2UVF1|intact:EBI-28975118|ensembl:ENSP00000354878 intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215 psi-mi:ki21a_human(display_long)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short) psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Shen et al. (2008) pubmed:19020088|imex:IM-17496 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6251680|imex:IM-17496-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000354878|ensembl:ENST00000361961|ensembl:ENSP00000354851|ensembl:ENST00000541463|ensembl:ENSP00000438075|ensembl:ENST00000544797|ensembl:ENSP00000445606|refseq:NP_001166934.1|refseq:NP_001166935.1|refseq:NP_001166936.1|refseq:NP_060111.2|refseq:XP_005269064.1|refseq:XP_005269070.1|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:1990939"|interpro:IPR001680(WD40 repeat)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036322|interpro:IPR036961|rcsb pdb:5D3A|rcsb pdb:5NFD|rcsb pdb:5YBU|rcsb pdb:5YBV|rcsb pdb:7KLJ|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-56253N ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/07/23 2014/10/16 rogid:GRF+n9Srey50s4v6s2Z2E23/x0s9606 rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606 intact-crc:E6EC0E24B5D1F426|rigid:JBEPYE0Jb2N/rW6tnplYvRITvkM false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9Y6D6 uniprotkb:Q7Z4S6-2 intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215 intact:EBI-6251716|ensembl:ENSP00000354851 psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym) psi-mi:q7z4s6-2(display_long)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2008) pubmed:19020088|imex:IM-17496 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6251761|imex:IM-17496-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N intact:EBI-2691397(isoform-parent)|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361961(transcript)|uniprotkb:Q7Z4S6-2(isoform-parent) - - - figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/07/23 2014/10/16 rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606 rogid:PxCZv8C7N5DQYJzOD0vEASHh8mU9606 intact-crc:8F804D416CBB9F85|rigid:7lNDrl514CWAkas+R7UsvlTl0c0 false green fluorescent protein tag:?-? necessary binding region:999-1661|ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7Z4S6-2 uniprotkb:Q9Y6D6 intact:EBI-6251716|ensembl:ENSP00000354851 intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215 psi-mi:q7z4s6-2(display_long)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym) psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shen et al. (2008) pubmed:19020088|imex:IM-17496 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6251750|imex:IM-17496-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2691397(isoform-parent)|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361961(transcript)|uniprotkb:Q7Z4S6-2(isoform-parent) ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/07/23 2014/10/16 rogid:PxCZv8C7N5DQYJzOD0vEASHh8mU9606 rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606 intact-crc:B06733ADD6D84068|rigid:7lNDrl514CWAkas+R7UsvlTl0c0 false ha tag:?-?|necessary binding region:999-1661 green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7Z4S6-2 uniprotkb:Q9Y6D6 intact:EBI-6251716|ensembl:ENSP00000354851 intact:EBI-1044254|uniprotkb:Q9NV46|uniprotkb:Q9UFV2|uniprotkb:Q9UNL0|ensembl:ENSP00000262215 psi-mi:q7z4s6-2(display_long)|uniprotkb:KIF21A(gene name)|psi-mi:KIF21A(display_short)|uniprotkb:KIAA1708(gene name synonym)|uniprotkb:KIF2(gene name synonym)|uniprotkb:Kinesin-like protein KIF2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-62(gene name synonym) psi-mi:big1_human(display_long)|uniprotkb:ARFGEF1(gene name)|psi-mi:ARFGEF1(display_short)|uniprotkb:ARFGEP1(gene name synonym)|uniprotkb:BIG1(gene name synonym)|uniprotkb:p200 ARF-GEP1(gene name synonym)|uniprotkb:p200 ARF guanine nucleotide exchange factor(gene name synonym)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shen et al. (2008) pubmed:19020088|imex:IM-17496 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6251707|imex:IM-17496-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2691397(isoform-parent)|ensembl:ENSG00000139116(gene)|ensembl:ENST00000361961(transcript)|uniprotkb:Q7Z4S6-2(isoform-parent) ensembl:ENSG00000066777(gene)|ensembl:ENST00000262215(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007030"(Golgi organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017022"(myosin binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090284"(positive regulation of protein glycosylation in Golgi)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR000904(SEC7-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|mint:Q9Y6D6|rcsb pdb:3LTL|rcsb pdb:5EE5|rcsb pdb:5J5C|go:"GO:0051897"(positive regulation of protein kinase B signaling)|refseq:NP_006412.2|refseq:XP_005251191.1|dip:DIP-29748N - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/07/23 2014/10/16 rogid:PxCZv8C7N5DQYJzOD0vEASHh8mU9606 rogid:HIXdg7zEoEpHcC+KwTUjNFSgr5M9606 intact-crc:5DDDD30190533717|rigid:7lNDrl514CWAkas+R7UsvlTl0c0 false necessary binding region:999-1661|ha tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)