#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P75830 uniprotkb:P02930 intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597 intact:EBI-875614|uniprotkb:Q2M9G5|ensemblbacteria:AAC76071|ensemblbacteria:BAE77091 psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name) psi-mi:tolc_ecoli(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:mtcB(gene name synonym)|uniprotkb:mukA(gene name synonym)|uniprotkb:refI(gene name synonym)|uniprotkb:Multidrug efflux pump subunit TolC(gene name synonym)|uniprotkb:Outer membrane factor TolC(gene name synonym)|uniprotkb:colE1-i(gene name synonym)|uniprotkb:toc(gene name synonym)|uniprotkb:weeA(gene name synonym)|uniprotkb:JW5503(locus name)|uniprotkb:b3035(locus name) psi-mi:"MI:0096"(pull down) Lin et al. (2009) pubmed:18955484|imex:IM-17851 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6305909|imex:IM-17851-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL refseq:NP_417507.2|refseq:WP_000735278.1|dip:DIP-11007N|ensemblbacteria:AAC76071(transcript)|ensemblbacteria:b3035(gene)|ensemblbacteria:BAE77091(gene)|ensemblbacteria:BAE77091(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0009279"(cell outer membrane)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042930"(enterobactin transport)|go:"GO:0045203"(integral component of cell outer membrane)|go:"GO:0046677"(response to antibiotic)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|interpro:IPR010130(Type I secretion outer membrane protein, TolC)|rcsb pdb:1EK9|rcsb pdb:1TQQ|rcsb pdb:2VDD|rcsb pdb:2VDE|rcsb pdb:2WMZ|rcsb pdb:2XMN|rcsb pdb:5NG5|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5O66|rcsb pdb:5V5S|rcsb pdb:6WXH|rcsb pdb:6WXI - - - figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/24 2014/10/16 rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333 rogid:67LQDsYiAt6tDwigzlhM3Pp5+JA83333 intact-crc:719E63EB191F3C1D|rigid:3ZrC3L2+BS1ofYgY9PXx0IoICUk false s tag:c-c his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P02930 uniprotkb:P75831 intact:EBI-875614|uniprotkb:Q2M9G5|ensemblbacteria:AAC76071|ensemblbacteria:BAE77091 intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 psi-mi:tolc_ecoli(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:mtcB(gene name synonym)|uniprotkb:mukA(gene name synonym)|uniprotkb:refI(gene name synonym)|uniprotkb:Multidrug efflux pump subunit TolC(gene name synonym)|uniprotkb:Outer membrane factor TolC(gene name synonym)|uniprotkb:colE1-i(gene name synonym)|uniprotkb:toc(gene name synonym)|uniprotkb:weeA(gene name synonym)|uniprotkb:JW5503(locus name)|uniprotkb:b3035(locus name) psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:"MI:0096"(pull down) Lin et al. (2009) pubmed:18955484|imex:IM-17851 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6305934|imex:IM-17851-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417507.2|refseq:WP_000735278.1|dip:DIP-11007N|ensemblbacteria:AAC76071(transcript)|ensemblbacteria:b3035(gene)|ensemblbacteria:BAE77091(gene)|ensemblbacteria:BAE77091(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0009279"(cell outer membrane)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042930"(enterobactin transport)|go:"GO:0045203"(integral component of cell outer membrane)|go:"GO:0046677"(response to antibiotic)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|interpro:IPR010130(Type I secretion outer membrane protein, TolC)|rcsb pdb:1EK9|rcsb pdb:1TQQ|rcsb pdb:2VDD|rcsb pdb:2VDE|rcsb pdb:2WMZ|rcsb pdb:2XMN|rcsb pdb:5NG5|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5O66|rcsb pdb:5V5S|rcsb pdb:6WXH|rcsb pdb:6WXI refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA - - - figure legend:Figure 1|comment:They detected interaction between TolC and MacB but the intensity of the band suggested a weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/24 2014/10/16 rogid:67LQDsYiAt6tDwigzlhM3Pp5+JA83333 rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 intact-crc:ECD2BF0F6C7E4BCC|rigid:1a/4S59qaclh1mYu1vNMHun6QQI false s tag:c-c his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P75831 uniprotkb:P75830 intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597 psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name) psi-mi:"MI:0096"(pull down) Lin et al. (2009) pubmed:18955484|imex:IM-17851 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6305944|imex:IM-17851-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL - - - figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/24 2014/10/16 rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333 intact-crc:742000B1E0BBBAE5|rigid:Vhdx3oWaGLF314MksZSj++wVzes false his tag:?-? tag:c-c|sufficient binding region:21-371 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P75831 uniprotkb:P75830 intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597 psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name) psi-mi:"MI:0030"(cross-linking study) Lin et al. (2009) pubmed:18955484|imex:IM-17851 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6305794|imex:IM-17851-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL - - - figure legend:Supplemental data Figure 2A|comment:crosslinking agent was DMS and participant detection method SDS-PAGE and MALDI-TOF.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/24 2014/10/16 rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333 intact-crc:4DCFA261A907BB90|rigid:Vhdx3oWaGLF314MksZSj++wVzes false his tag:?-? his tag:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P75831 uniprotkb:P75831 intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Lin et al. (2009) pubmed:18955484|imex:IM-17851 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6306236|imex:IM-17851-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA - - - figure legend:Supplemental data Figure 2B|comment:The most abundant band on the gel was indicative of a dimer. However, there were several higher-Mr bands also present that would suggest that the protein can form higher-order oligomers.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/24 2014/10/16 rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 intact-crc:0725AE571C9921EF|rigid:R62qgztOgULEgXhz9fhDQF4u20c false his tag:?-? his tag:?-? 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P75831 uniprotkb:P75831 intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Lin et al. (2009) pubmed:18955484|imex:IM-17851 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6306312|imex:IM-17851-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA - - - figure legend:Figure 3A, 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/09/24 2014/10/16 rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 intact-crc:01C8D7C3928E8B43|rigid:R62qgztOgULEgXhz9fhDQF4u20c false his tag:?-? his tag:?-? 2 0 psi-mi:"MI:0815"(confirmation by molecular weight) psi-mi:"MI:0815"(confirmation by molecular weight) uniprotkb:P75831 uniprotkb:P75831 intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:"MI:0872"(atomic force microscopy) Lin et al. (2009) pubmed:18955484|imex:IM-17851 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6306328|imex:IM-17851-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA - - - figure legend:Figure 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/24 2014/10/16 rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 intact-crc:975C7C42AD258AE9|rigid:R62qgztOgULEgXhz9fhDQF4u20c false his tag:?-? his tag:?-? 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P75831 uniprotkb:P75831 intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Lin et al. (2009) pubmed:18955484|imex:IM-17851 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6393856|imex:IM-17851-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA - - - figure legend:Figure 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/09/24 2014/10/16 rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 intact-crc:BA5299C96A33D59F|rigid:R62qgztOgULEgXhz9fhDQF4u20c false his tag:?-? his tag:?-? 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:15422" uniprotkb:P75831 intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249" intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name) psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:"MI:0880"(atpase assay) Lin et al. (2009) pubmed:18955484|imex:IM-17851 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6393974|imex:IM-17851-11 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA go:0006200|go:0016887 - - figure legend:Figure 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/24 2014/10/16 - rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 intact-crc:460523FD610ABEAB false - his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:15422" uniprotkb:P75830 intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249" intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597 psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name) psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name) psi-mi:"MI:0880"(atpase assay) Lin et al. (2009) pubmed:18955484|imex:IM-17851 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6393991|imex:IM-17851-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL go:0006200|go:0016887 - - figure legend:Figure 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/24 2014/10/16 - rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333 intact-crc:B7E6AFAF4C7F5BB0 false - his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:15422" uniprotkb:P75831 intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249" intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598 psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name) psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym) psi-mi:"MI:0880"(atpase assay) Lin et al. (2009) pubmed:18955484|imex:IM-17851 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6393991|imex:IM-17851-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA go:0006200|go:0016887 - - figure legend:Figure 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/24 2014/10/16 - rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333 intact-crc:B7E6AFAF4C7F5BB0 false - his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)