#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00579 uniprotkb:P00579 intact:EBI-545104|uniprotkb:Q2M9D8|ensemblbacteria:AAC76103|ensemblbacteria:BAE77118 intact:EBI-545104|uniprotkb:Q2M9D8|ensemblbacteria:AAC76103|ensemblbacteria:BAE77118 psi-mi:rpod_ecoli(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:alt(gene name synonym)|uniprotkb:b3067(locus name)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:JW3039(locus name) psi-mi:rpod_ecoli(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:alt(gene name synonym)|uniprotkb:b3067(locus name)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:JW3039(locus name) psi-mi:"MI:0018"(two hybrid) Yuan et al. (2008) pubmed:18826409|imex:IM-18237 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6504980|mpidb:MPIDB-INT-72|imex:IM-18237-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417539.1|refseq:WP_000437376.1|ensemblbacteria:AAC76103(transcript)|ensemblbacteria:b3067(gene)|ensemblbacteria:BAE77118(gene)|ensemblbacteria:BAE77118(transcript)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016987"(sigma factor activity)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR028630|interpro:IPR036388|interpro:IPR042189|rcsb pdb:1SIG|rcsb pdb:1TLH|rcsb pdb:2P7V|rcsb pdb:3IYD|rcsb pdb:3T72|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4JKR|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4LJZ|rcsb pdb:4LK0|rcsb pdb:4LK1|rcsb pdb:4LLG|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YFK|rcsb pdb:4YFN|rcsb pdb:4YFX|rcsb pdb:4YG2|rcsb pdb:4YLN|rcsb pdb:4YLO|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6B6H|rcsb pdb:6BYU|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6OUL|rcsb pdb:6P18|rcsb pdb:6P1K|rcsb pdb:6PB4|rcsb pdb:6PB5|rcsb pdb:6PB6|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6VJS|rcsb pdb:6XH7|rcsb pdb:6XH8|rcsb pdb:6XL5|rcsb pdb:6XL9|rcsb pdb:6XLJ|rcsb pdb:6XLL|rcsb pdb:6XLM|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|dip:DIP-10773N refseq:NP_417539.1|refseq:WP_000437376.1|ensemblbacteria:AAC76103(transcript)|ensemblbacteria:b3067(gene)|ensemblbacteria:BAE77118(gene)|ensemblbacteria:BAE77118(transcript)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016987"(sigma factor activity)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR028630|interpro:IPR036388|interpro:IPR042189|rcsb pdb:1SIG|rcsb pdb:1TLH|rcsb pdb:2P7V|rcsb pdb:3IYD|rcsb pdb:3T72|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4JKR|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4LJZ|rcsb pdb:4LK0|rcsb pdb:4LK1|rcsb pdb:4LLG|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YFK|rcsb pdb:4YFN|rcsb pdb:4YFX|rcsb pdb:4YG2|rcsb pdb:4YLN|rcsb pdb:4YLO|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6B6H|rcsb pdb:6BYU|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6OUL|rcsb pdb:6P18|rcsb pdb:6P1K|rcsb pdb:6PB4|rcsb pdb:6PB5|rcsb pdb:6PB6|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6VJS|rcsb pdb:6XH7|rcsb pdb:6XH8|rcsb pdb:6XL5|rcsb pdb:6XL9|rcsb pdb:6XLJ|rcsb pdb:6XLL|rcsb pdb:6XLM|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|dip:DIP-10773N - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/11/30 2014/10/16 rogid:jwUTAy6Qbz6rbF+rdM60BZQcmKM83333 rogid:jwUTAy6Qbz6rbF+rdM60BZQcmKM83333 intact-crc:A8D1D65966F6BB82|rigid:llhNEHpFyOUh2irvdvnwI0LzywA false sufficient binding region:536..536-613|mutation increasing interaction strength:563-563 mutation increasing interaction strength:388-388|sufficient binding region:371..371-456..456 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00579 uniprotkb:P0AFX4 intact:EBI-545104|uniprotkb:Q2M9D8|ensemblbacteria:AAC76103|ensemblbacteria:BAE77118 intact:EBI-1134364|uniprotkb:P31690|uniprotkb:Q2M8T2|ensemblbacteria:AAC76969|ensemblbacteria:BAE77324 psi-mi:rpod_ecoli(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:alt(gene name synonym)|uniprotkb:b3067(locus name)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:JW3039(locus name) psi-mi:rsd_ecoli(display_long)|uniprotkb:rsd(gene name)|psi-mi:rsd(display_short)|uniprotkb:b3995(locus name)|uniprotkb:JW3959(locus name) psi-mi:"MI:0018"(two hybrid) Yuan et al. (2008) pubmed:18826409|imex:IM-18237 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6504980|mpidb:MPIDB-INT-72|imex:IM-18237-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417539.1|refseq:WP_000437376.1|ensemblbacteria:AAC76103(transcript)|ensemblbacteria:b3067(gene)|ensemblbacteria:BAE77118(gene)|ensemblbacteria:BAE77118(transcript)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016987"(sigma factor activity)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR028630|interpro:IPR036388|interpro:IPR042189|rcsb pdb:1SIG|rcsb pdb:1TLH|rcsb pdb:2P7V|rcsb pdb:3IYD|rcsb pdb:3T72|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4JKR|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4LJZ|rcsb pdb:4LK0|rcsb pdb:4LK1|rcsb pdb:4LLG|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YFK|rcsb pdb:4YFN|rcsb pdb:4YFX|rcsb pdb:4YG2|rcsb pdb:4YLN|rcsb pdb:4YLO|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6B6H|rcsb pdb:6BYU|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6OUL|rcsb pdb:6P18|rcsb pdb:6P1K|rcsb pdb:6PB4|rcsb pdb:6PB5|rcsb pdb:6PB6|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6VJS|rcsb pdb:6XH7|rcsb pdb:6XH8|rcsb pdb:6XL5|rcsb pdb:6XL9|rcsb pdb:6XLJ|rcsb pdb:6XLL|rcsb pdb:6XLM|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|dip:DIP-10773N refseq:WP_000934302.1|refseq:NP_418423.1|ensemblbacteria:AAC76969(transcript)|ensemblbacteria:b3995(gene)|ensemblbacteria:BAE77324(gene)|ensemblbacteria:BAE77324(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016989"(sigma factor antagonist activity)|interpro:IPR007448("Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ")|interpro:IPR023785|interpro:IPR038309|rcsb pdb:2P7V|rcsb pdb:4XWJ|dip:DIP-10800N - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/11/30 2014/10/16 rogid:jwUTAy6Qbz6rbF+rdM60BZQcmKM83333 rogid:pFLawTFBnJPwkvIVB7Ujtsrwy5E83333 intact-crc:A8D1D65966F6BB82|rigid:llhNEHpFyOUh2irvdvnwI0LzywA false sufficient binding region:536..536-613|mutation increasing interaction strength:563-563 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00579 uniprotkb:P0AFX4 intact:EBI-545104|uniprotkb:Q2M9D8|ensemblbacteria:AAC76103|ensemblbacteria:BAE77118 intact:EBI-1134364|uniprotkb:P31690|uniprotkb:Q2M8T2|ensemblbacteria:AAC76969|ensemblbacteria:BAE77324 psi-mi:rpod_ecoli(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:alt(gene name synonym)|uniprotkb:b3067(locus name)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:JW3039(locus name) psi-mi:rsd_ecoli(display_long)|uniprotkb:rsd(gene name)|psi-mi:rsd(display_short)|uniprotkb:b3995(locus name)|uniprotkb:JW3959(locus name) psi-mi:"MI:0018"(two hybrid) Yuan et al. (2008) pubmed:18826409|imex:IM-18237 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6404560|mpidb:MPIDB-INT-72|imex:IM-18237-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417539.1|refseq:WP_000437376.1|ensemblbacteria:AAC76103(transcript)|ensemblbacteria:b3067(gene)|ensemblbacteria:BAE77118(gene)|ensemblbacteria:BAE77118(transcript)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016987"(sigma factor activity)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR028630|interpro:IPR036388|interpro:IPR042189|rcsb pdb:1SIG|rcsb pdb:1TLH|rcsb pdb:2P7V|rcsb pdb:3IYD|rcsb pdb:3T72|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4JKR|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4LJZ|rcsb pdb:4LK0|rcsb pdb:4LK1|rcsb pdb:4LLG|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YFK|rcsb pdb:4YFN|rcsb pdb:4YFX|rcsb pdb:4YG2|rcsb pdb:4YLN|rcsb pdb:4YLO|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6B6H|rcsb pdb:6BYU|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6OUL|rcsb pdb:6P18|rcsb pdb:6P1K|rcsb pdb:6PB4|rcsb pdb:6PB5|rcsb pdb:6PB6|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6VJS|rcsb pdb:6XH7|rcsb pdb:6XH8|rcsb pdb:6XL5|rcsb pdb:6XL9|rcsb pdb:6XLJ|rcsb pdb:6XLL|rcsb pdb:6XLM|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|dip:DIP-10773N refseq:WP_000934302.1|refseq:NP_418423.1|ensemblbacteria:AAC76969(transcript)|ensemblbacteria:b3995(gene)|ensemblbacteria:BAE77324(gene)|ensemblbacteria:BAE77324(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016989"(sigma factor antagonist activity)|interpro:IPR007448("Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ")|interpro:IPR023785|interpro:IPR038309|rcsb pdb:2P7V|rcsb pdb:4XWJ|dip:DIP-10800N - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/11/30 2014/10/16 rogid:jwUTAy6Qbz6rbF+rdM60BZQcmKM83333 rogid:pFLawTFBnJPwkvIVB7Ujtsrwy5E83333 intact-crc:58778BB54E00E80F|rigid:llhNEHpFyOUh2irvdvnwI0LzywA false sufficient binding region:536..536-613 mutation increasing interaction strength:14-14,34-34|mutation decreasing interaction strength:34-34|mutation increasing interaction strength:14-14 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0AFX4 uniprotkb:P00579 intact:EBI-1134364|uniprotkb:P31690|uniprotkb:Q2M8T2|ensemblbacteria:AAC76969|ensemblbacteria:BAE77324 intact:EBI-545104|uniprotkb:Q2M9D8|ensemblbacteria:AAC76103|ensemblbacteria:BAE77118 psi-mi:rsd_ecoli(display_long)|uniprotkb:rsd(gene name)|psi-mi:rsd(display_short)|uniprotkb:b3995(locus name)|uniprotkb:JW3959(locus name) psi-mi:rpod_ecoli(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:alt(gene name synonym)|uniprotkb:b3067(locus name)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:JW3039(locus name) psi-mi:"MI:0018"(two hybrid) Yuan et al. (2008) pubmed:18826409|imex:IM-18237 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6504743|mpidb:MPIDB-INT-72|imex:IM-18237-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000934302.1|refseq:NP_418423.1|ensemblbacteria:AAC76969(transcript)|ensemblbacteria:b3995(gene)|ensemblbacteria:BAE77324(gene)|ensemblbacteria:BAE77324(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016989"(sigma factor antagonist activity)|interpro:IPR007448("Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ")|interpro:IPR023785|interpro:IPR038309|rcsb pdb:2P7V|rcsb pdb:4XWJ|dip:DIP-10800N refseq:NP_417539.1|refseq:WP_000437376.1|ensemblbacteria:AAC76103(transcript)|ensemblbacteria:b3067(gene)|ensemblbacteria:BAE77118(gene)|ensemblbacteria:BAE77118(transcript)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016987"(sigma factor activity)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR028630|interpro:IPR036388|interpro:IPR042189|rcsb pdb:1SIG|rcsb pdb:1TLH|rcsb pdb:2P7V|rcsb pdb:3IYD|rcsb pdb:3T72|rcsb pdb:4JK1|rcsb pdb:4JK2|rcsb pdb:4JKR|rcsb pdb:4KMU|rcsb pdb:4KN4|rcsb pdb:4KN7|rcsb pdb:4LJZ|rcsb pdb:4LK0|rcsb pdb:4LK1|rcsb pdb:4LLG|rcsb pdb:4MEX|rcsb pdb:4MEY|rcsb pdb:4XSX|rcsb pdb:4XSY|rcsb pdb:4XSZ|rcsb pdb:4YFK|rcsb pdb:4YFN|rcsb pdb:4YFX|rcsb pdb:4YG2|rcsb pdb:4YLN|rcsb pdb:4YLO|rcsb pdb:4YLP|rcsb pdb:4ZH2|rcsb pdb:4ZH3|rcsb pdb:4ZH4|rcsb pdb:5UAC|rcsb pdb:5UAG|rcsb pdb:5UAH|rcsb pdb:5UAJ|rcsb pdb:5UAL|rcsb pdb:5UAQ|rcsb pdb:5VSW|rcsb pdb:5VT0|rcsb pdb:5W1S|rcsb pdb:5W1T|rcsb pdb:6B6H|rcsb pdb:6BYU|rcsb pdb:6C9Y|rcsb pdb:6CA0|rcsb pdb:6CUX|rcsb pdb:6JNX|rcsb pdb:6K4Y|rcsb pdb:6LDI|rcsb pdb:6N4C|rcsb pdb:6N57|rcsb pdb:6N58|rcsb pdb:6OUL|rcsb pdb:6P18|rcsb pdb:6P1K|rcsb pdb:6PB4|rcsb pdb:6PB5|rcsb pdb:6PB6|rcsb pdb:6PSQ|rcsb pdb:6PSR|rcsb pdb:6PSS|rcsb pdb:6PST|rcsb pdb:6PSU|rcsb pdb:6PSV|rcsb pdb:6PSW|rcsb pdb:6VJS|rcsb pdb:6XH7|rcsb pdb:6XH8|rcsb pdb:6XL5|rcsb pdb:6XL9|rcsb pdb:6XLJ|rcsb pdb:6XLL|rcsb pdb:6XLM|rcsb pdb:7C17|rcsb pdb:7C97|rcsb pdb:7CHW|rcsb pdb:7KHB|rcsb pdb:7KHC|rcsb pdb:7KHE|rcsb pdb:7KHI|dip:DIP-10773N - - - figure legend:Fig. 2C, 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/11/30 2014/10/16 rogid:pFLawTFBnJPwkvIVB7Ujtsrwy5E83333 rogid:jwUTAy6Qbz6rbF+rdM60BZQcmKM83333 intact-crc:D1CE60FB5B78CB4F|rigid:llhNEHpFyOUh2irvdvnwI0LzywA false mutation disrupting interaction strength:142-142|mutation increasing interaction strength:14-14,34-34|mutation increasing interaction strength:34-34|mutation increasing interaction strength:14-14 mutation increasing interaction strength:388-388|mutation decreasing interaction strength:385-385|sufficient binding region:371..371-456..456|mutation decreasing interaction strength:401-401 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26480 uniprotkb:P26480 intact:EBI-2013679|ensemblbacteria:AAG03965 intact:EBI-2013679|ensemblbacteria:AAG03965 psi-mi:rpod_pseae(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:rpoDA(gene name synonym)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:PA0576(locus name) psi-mi:rpod_pseae(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:rpoDA(gene name synonym)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:PA0576(locus name) psi-mi:"MI:0018"(two hybrid) Yuan et al. (2008) pubmed:18826409|imex:IM-18237 taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)") taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6404550|mpidb:MPIDB-INT-206|imex:IM-18237-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028630|refseq:NP_249267.1|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR042189|refseq:WP_003085035.1|interpro:IPR036388|ensemblbacteria:AAG03965(transcript)|ensemblbacteria:PA0576(gene)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016987"(sigma factor activity) interpro:IPR028630|refseq:NP_249267.1|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR042189|refseq:WP_003085035.1|interpro:IPR036388|ensemblbacteria:AAG03965(transcript)|ensemblbacteria:PA0576(gene)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016987"(sigma factor activity) - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/11/30 2014/10/16 rogid:40RLoV6gLPJnSH1vDt1VyBT8Evg208964 rogid:40RLoV6gLPJnSH1vDt1VyBT8Evg208964 intact-crc:F64B01D8794A1514|rigid:gi5EpzwS26KWSXYH8fh90NNVQIg false sufficient binding region:540..540-617 sufficient binding region:375..375-460..460 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26480 uniprotkb:P15275 intact:EBI-2013679|ensemblbacteria:AAG03965 intact:EBI-2013699|ensemblbacteria:AAG08640 psi-mi:rpod_pseae(display_long)|uniprotkb:rpoD(gene name)|psi-mi:rpoD(display_short)|uniprotkb:rpoDA(gene name synonym)|uniprotkb:Sigma-70(gene name synonym)|uniprotkb:PA0576(locus name) psi-mi:algq_pseae(display_long)|uniprotkb:algQ(gene name)|psi-mi:algQ(display_short)|uniprotkb:algR2(gene name synonym)|uniprotkb:Alginate regulatory protein AlgR2(gene name synonym)|uniprotkb:PA5255(locus name) psi-mi:"MI:0018"(two hybrid) Yuan et al. (2008) pubmed:18826409|imex:IM-18237 taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)") taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6404550|mpidb:MPIDB-INT-206|imex:IM-18237-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028630|refseq:NP_249267.1|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR007631(RNA polymerase sigma factor 70, non-essential region)|interpro:IPR007127(RNA polymerase sigma factor 70, region 1.1)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR042189|refseq:WP_003085035.1|interpro:IPR036388|ensemblbacteria:AAG03965(transcript)|ensemblbacteria:PA0576(gene)|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016987"(sigma factor activity) interpro:IPR007448("Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ")|refseq:NP_253942.1|refseq:WP_003120370.1|interpro:IPR038309|ensemblbacteria:AAG08640(transcript)|ensemblbacteria:PA5255(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042121"(alginic acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:1900192"(positive regulation of single-species biofilm formation)|go:"GO:1900378"(positive regulation of secondary metabolite biosynthetic process) - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/11/30 2014/10/16 rogid:40RLoV6gLPJnSH1vDt1VyBT8Evg208964 rogid:aT9VpS4azujW9FcQ8M9IzK/R/Oo208964 intact-crc:F64B01D8794A1514|rigid:gi5EpzwS26KWSXYH8fh90NNVQIg false sufficient binding region:540..540-617 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)