#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UBU9	uniprotkb:P46060	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262548|imex:IM-17666-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606	intact-crc:AAA86A419C31899B|rigid:8edlQWBEis9rP1/cTNVwjCHV/qA	false	flag tag:?-?|sufficient binding region:1-583	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:Q8WUM0	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262548|imex:IM-17666-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606	intact-crc:AAA86A419C31899B|rigid:8edlQWBEis9rP1/cTNVwjCHV/qA	false	flag tag:?-?|sufficient binding region:1-583	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:Q99567	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-726178|uniprotkb:Q9BWE5|uniprotkb:D3DTM2|intact:EBI-28967918|ensembl:ENSP00000458954	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:nup88_human(display_long)|uniprotkb:Nucleoporin Nup88(gene name synonym)|uniprotkb:88 kDa nucleoporin(gene name synonym)|uniprotkb:NUP88(gene name)|psi-mi:NUP88(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262548|imex:IM-17666-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	ensembl:ENSP00000458954|refseq:NP_002523.2|refseq:NP_001307582.1|ensembl:ENSG00000108559(gene)|ensembl:ENST00000573584(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005215"(transporter activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|interpro:IPR019321|interpro:IPR037700|mint:Q99567|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:4e7YTurNWkXUn9zj0JiD2muc94A9606	intact-crc:AAA86A419C31899B|rigid:8edlQWBEis9rP1/cTNVwjCHV/qA	false	flag tag:?-?|sufficient binding region:1-583	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:P49790	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-286779|uniprotkb:Q5T9I7|intact:EBI-1237421|uniprotkb:E7EPX5|uniprotkb:Q4LE47|uniprotkb:Q7Z743|uniprotkb:B4DIK2|uniprotkb:F6QR24|ensembl:ENSP00000262077	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:nu153_human(display_long)|uniprotkb:Nucleoporin Nup153(gene name synonym)|uniprotkb:153 kDa nucleoporin(gene name synonym)|uniprotkb:NUP153(gene name)|psi-mi:NUP153(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262548|imex:IM-17666-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	ensembl:ENSP00000262077|ensembl:ENST00000537253|ensembl:ENSP00000444029|ensembl:ENST00000613258|ensembl:ENSP00000478627|refseq:NP_005115.2|refseq:NP_001265138.1|refseq:NP_001265139.1|dip:DIP-38185N|ensembl:ENSG00000124789(gene)|ensembl:ENST00000262077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043657"(host cell)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046832"(negative regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR013913(Nucleoporin, Nup153-like)|interpro:IPR018892|interpro:IPR026054|interpro:IPR036443|mint:P49790|rcsb pdb:2EBQ|rcsb pdb:2EBR|rcsb pdb:2EBV|rcsb pdb:2GQE|rcsb pdb:4U0C|rcsb pdb:4U0D|rcsb pdb:5TSV|rcsb pdb:5TSX|rcsb pdb:6AYA|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:rOax/ikcAu5fmDiCOauVr7Y/fzY9606	intact-crc:AAA86A419C31899B|rigid:8edlQWBEis9rP1/cTNVwjCHV/qA	false	flag tag:?-?|sufficient binding region:1-583	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:P35658	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262548|imex:IM-17666-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	ensembl:ENSP00000352400|ensembl:ENST00000411637|ensembl:ENSP00000396576|refseq:NP_005076.3|refseq:NP_001305253.1|refseq:NP_001305254.1|dip:DIP-38367N|rcsb pdb:3FMP|rcsb pdb:5DIS|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|rcsb pdb:3FMO|ensembl:ENSG00000126883(gene)|ensembl:ENST00000359428(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990876"(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606	intact-crc:AAA86A419C31899B|rigid:8edlQWBEis9rP1/cTNVwjCHV/qA	false	flag tag:?-?|sufficient binding region:1-583	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:P37198	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262548|imex:IM-17666-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:AAA86A419C31899B|rigid:8edlQWBEis9rP1/cTNVwjCHV/qA	false	flag tag:?-?|sufficient binding region:1-583	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:P49792	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-973138|intact:EBI-28970106|ensembl:ENSP00000283195|uniprotkb:Q13074|uniprotkb:Q15280|uniprotkb:Q53TE2|uniprotkb:Q59FH7	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:rbp2_human(display_long)|uniprotkb:RANBP2(gene name)|psi-mi:RANBP2(display_short)|uniprotkb:NUP358(gene name synonym)|uniprotkb:Ran-binding protein 2(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup358(gene name synonym)|uniprotkb:Nucleoporin Nup358(gene name synonym)|uniprotkb:358 kDa nucleoporin(gene name synonym)|uniprotkb:p270(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262548|imex:IM-17666-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	ensembl:ENSG00000153201(gene)|ensembl:ENST00000283195(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006457"(protein folding)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR000156(Ran Binding Protein 1)|reactome:R-HSA-168271|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR022011|interpro:IPR029000|interpro:IPR036443|mint:P49792|reactome:R-HSA-168276|rcsb pdb:1RRP|reactome:R-HSA-168325|reactome:R-HSA-168333|rcsb pdb:1XKE|rcsb pdb:1Z5S|rcsb pdb:2LAS|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4GA0|rcsb pdb:4I9Y|rcsb pdb:4L6E|rcsb pdb:4LQW|rcsb pdb:5CLL|rcsb pdb:5CLQ|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-170822|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-180746|reactome:R-HSA-9648025|ensembl:ENSP00000283195|refseq:NP_006258.3|dip:DIP-37654N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:KB+rjfw8djVygvDpTncA0NO2MDY9606	intact-crc:AAA86A419C31899B|rigid:8edlQWBEis9rP1/cTNVwjCHV/qA	false	flag tag:?-?|sufficient binding region:1-583	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:Q07955	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:P36578	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-348313|ensembl:ENSP00000311430|uniprotkb:P39029|uniprotkb:Q4VBR0|uniprotkb:Q969Z9|uniprotkb:A8K502	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:rl4_human(display_long)|uniprotkb:RPL4(gene name)|psi-mi:RPL4(display_short)|uniprotkb:RPL1(gene name synonym)|uniprotkb:60S ribosomal protein L1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	ensembl:ENSG00000174444(gene)|ensembl:ENST00000307961(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR025755|mint:P36578|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|interpro:IPR023574|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OM0|refseq:NP_000959.2|dip:DIP-27559N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:34il/jyrW0Dqj0eA8GBFgUk05XU9606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:Q14444	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-1047080|uniprotkb:Q15074|intact:EBI-1171814|uniprotkb:Q6IMN4|uniprotkb:A6NMY7|uniprotkb:Q6IMN7|uniprotkb:Q9BV09|intact:EBI-2562858|intact:EBI-3449178|uniprotkb:D3DR06|ensembl:ENSP00000340329|ensembl:ENSP00000434150	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:capr1_human(display_long)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNG105(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_005889.3|refseq:NP_976240.1|ensembl:ENSG00000135387(gene)|ensembl:ENST00000341394(transcript)|ensembl:ENST00000532820(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0045202"(synapse)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|interpro:IPR022070|interpro:IPR028816|interpro:IPR041637|mint:Q14444|rcsb pdb:4WBE|rcsb pdb:4WBP|rcsb pdb:6TA7|refseq:XP_016873238.1	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:3c6ZdBClP/D6jIi8NfzBkMc61pI9606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:Q9Y2W1	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-352039|uniprotkb:Q5VTK6|uniprotkb:D3DPS5|ensembl:ENSP00000346634|ensembl:ENSP00000433825	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:tr150_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 2(gene name synonym)|uniprotkb:BCLAF2(gene name synonym)|uniprotkb:THRAP3(gene name)|psi-mi:THRAP3(display_short)|uniprotkb:TRAP150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_005110.2|ensembl:ENSG00000054118(gene)|ensembl:ENST00000354618(transcript)|ensembl:ENST00000469141(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026667|interpro:IPR029199|mint:Q9Y2W1|reactome:R-HSA-1989781|reactome:R-HSA-381340|refseq:NP_001308400.1|refseq:NP_001308402.1	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:pPyZVG1IXg/+QDpHngwzUX09cBM9606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:P39023	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:O00571	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:P62424	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:Q02878	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:P62753	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:beDuXCIqL99V9JlVfpzx7MdpH689606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:P23396	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:P62917	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:Q08211	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body)	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:P19338	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:Q00839	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262560|imex:IM-17666-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606	intact-crc:B9DDD2CAA4A098F0|rigid:ZX88GKX3ArcYQks5WbSCztlRV58	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9UBU9	uniprotkb:O00571	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262612|imex:IM-17666-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)	-	-	figure legend:1C and 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	intact-crc:CE7AFADF3F530E7F|rigid:5US9NQ4Avip7XtvWCoM+mixwWhk	false	flag tag:?-?|sufficient binding region:1-583	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00571	uniprotkb:Q9UBU9	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262618|imex:IM-17666-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	-	-	-	figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	intact-crc:FE85229793E72FDF|rigid:5US9NQ4Avip7XtvWCoM+mixwWhk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11940	uniprotkb:O00571	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262645|imex:IM-17666-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	-	-	-	figure legend:S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	intact-crc:0FC113B4E171F223|rigid:64Ol4fwp2battejmiWdFsGLEXCw	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00571	uniprotkb:Q9UBU9	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262632|imex:IM-17666-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	-	-	-	figure legend:1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/03	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	intact-crc:C76DF4A15FE21007|rigid:5US9NQ4Avip7XtvWCoM+mixwWhk	false	glutathione s tranferase tag:?-?|sufficient binding region:2-227|sufficient binding region:537-662	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P11940	uniprotkb:Q9UBU9	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262659|imex:IM-17666-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	-	-	-	figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	intact-crc:23DE91C9FC30A4E8|rigid:TobCXz3VLWDK4UwMqOirf7ncH+o	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00571	uniprotkb:P11940	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262667|imex:IM-17666-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	-	-	-	figure legend:5A|comment:"(Transfected) eIF4A was also found associated."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	intact-crc:B11E3A7AFF267FD3|rigid:sBizq24CLofXS6MAoJjXFQ6duiM	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00571	uniprotkb:P05198	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-1056162|ensembl:ENSP00000256383|ensembl:ENSP00000425299	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:if2a_human(display_long)|uniprotkb:EIF2S1(gene name)|psi-mi:EIF2S1(display_short)|uniprotkb:EIF2A(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262667|imex:IM-17666-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	refseq:NP_004085.1|ensembl:ENSG00000134001(gene)|ensembl:ENST00000256383(transcript)|ensembl:ENST00000466499(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|mint:P05198|rcsb pdb:1KL9|rcsb pdb:1Q8K|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|dip:DIP-39418N	-	-	-	figure legend:5A|comment:"(Transfected) eIF4A was also found associated."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:hG3fLbQuFpe5z8zS/bt/TnpEpzA9606	intact-crc:B11E3A7AFF267FD3|rigid:sBizq24CLofXS6MAoJjXFQ6duiM	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00571	uniprotkb:P05198	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-1056162|ensembl:ENSP00000256383|ensembl:ENSP00000425299	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:if2a_human(display_long)|uniprotkb:EIF2S1(gene name)|psi-mi:EIF2S1(display_short)|uniprotkb:EIF2A(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym)	psi-mi:"MI:0027"(cosedimentation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262690|imex:IM-17666-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	refseq:NP_004085.1|ensembl:ENSG00000134001(gene)|ensembl:ENST00000256383(transcript)|ensembl:ENST00000466499(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|mint:P05198|rcsb pdb:1KL9|rcsb pdb:1Q8K|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|dip:DIP-39418N	-	-	-	figure legend:5B|comment:Cosedimented ribososme 40S and eIF4G.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:hG3fLbQuFpe5z8zS/bt/TnpEpzA9606	intact-crc:B9E46800FB1E4230|rigid:itKRRtSruJoHgqJPiDsBu0zbknA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00571	uniprotkb:P06730	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0027"(cosedimentation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262690|imex:IM-17666-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N	-	-	-	figure legend:5B|comment:Cosedimented ribososme 40S and eIF4G.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606	intact-crc:B9E46800FB1E4230|rigid:itKRRtSruJoHgqJPiDsBu0zbknA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00571	uniprotkb:P55010	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-286450|uniprotkb:Q9H5N2|uniprotkb:Q9UG48|uniprotkb:Q53XB3|ensembl:ENSP00000216554|ensembl:ENSP00000376477|ensembl:ENSP00000453743	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:if5_human(display_long)|uniprotkb:EIF5(gene name)|psi-mi:EIF5(display_short)	psi-mi:"MI:0027"(cosedimentation)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262690|imex:IM-17666-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	refseq:NP_001960.2|refseq:NP_892116.2|ensembl:ENSG00000100664(gene)|ensembl:ENST00000216554(transcript)|ensembl:ENST00000392715(transcript)|ensembl:ENST00000558506(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|mint:P55010|rcsb pdb:2E9H|rcsb pdb:2G2K|rcsb pdb:2IU1|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:5B|comment:Cosedimented ribososme 40S and eIF4G.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/08/03	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:lM5AZJWJOQGbxADfl8MGCx3JAXc9606	intact-crc:B9E46800FB1E4230|rigid:itKRRtSruJoHgqJPiDsBu0zbknA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00571	uniprotkb:Q9UBU9	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262723|imex:IM-17666-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	go:"GO:0005737"(cytoplasm)	-	-	figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/08/03	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	intact-crc:B4DEFDE3D285E8D1|rigid:5US9NQ4Avip7XtvWCoM+mixwWhk	false	green fluorescent protein tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O00571	uniprotkb:P06730	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262734|imex:IM-17666-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N	go:"GO:0005737"(cytoplasm)	-	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/08/03	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606	intact-crc:AFF237E0072B7EB8|rigid:a3+Jor6dhcbdcN+Cd0PFwy8RQd4	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P31483	uniprotkb:O00571	intact:EBI-1387216|uniprotkb:Q53SS9|uniprotkb:Q96B58|ensembl:ENSP00000401371	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	psi-mi:tia1_human(display_long)|uniprotkb:TIA1(gene name)|psi-mi:TIA1(display_short)|uniprotkb:p40-TIA-1(gene name synonym)|uniprotkb:RNA-binding protein TIA-1(gene name synonym)|uniprotkb:T-cell-restricted intracellular antigen-1(gene name synonym)	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262705|imex:IM-17666-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071320.2|refseq:NP_071505.2|ensembl:ENSG00000116001(gene)|ensembl:ENST00000433529(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034830|interpro:IPR034832|interpro:IPR035979|rcsb pdb:2MJN|rcsb pdb:3BS9|rcsb pdb:5ITH|rcsb pdb:5O2V|rcsb pdb:5O3J|rcsb pdb:6ELD|reactome:R-HSA-6803529|mint:P31483	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	go:"GO:0005737"(cytoplasm)	-	-	figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/08/03	2014/10/16	rogid:d2ecwJo5sjSY6a/By3GM3B5A6PE9606	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	intact-crc:347DA7A4366498C9|rigid:2no+kn2r04tlVSnd5/b+MUx4qWM	false	ha tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O00571	uniprotkb:P11940	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262741|imex:IM-17666-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	go:"GO:0005737"(cytoplasm)	-	-	figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/08/03	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	intact-crc:32EAE643C1F0130F|rigid:64Ol4fwp2battejmiWdFsGLEXCw	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q15717	uniprotkb:O00571	intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym)	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Lai et al. (2008)	pubmed:18596238|imex:IM-17666	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6262714|imex:IM-17666-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	go:"GO:0005737"(cytoplasm)	-	-	figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/08/03	2014/10/16	rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	intact-crc:9548D3F089DD55C4|rigid:56xUZvWX5ThdesRUfYFDr69cRsc	false	ha tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)