#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y3Y4 uniprotkb:O00512 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-533127|uniprotkb:Q5T489|intact:EBI-28969406|ensembl:ENSP00000234739 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:bcl9_human(display_long)|uniprotkb:Protein legless homolog(gene name synonym)|uniprotkb:BCL9(gene name)|psi-mi:BCL9(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fiedler et al. (2008) pubmed:18498752|imex:IM-17354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6142552|rcsb pdb:2vpd|imex:IM-17354-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 ensembl:ENSP00000234739|ensembl:ENSG00000116128(gene)|ensembl:ENST00000234739(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:O00512|rcsb pdb:2GL7|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|rcsb pdb:3SL9|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:NP_004317.2|refseq:XP_005273028.1 - - - figure legend:Table 1 and 2|3d-resolution:2.77A|3d-r-factors:Rworking = 0.23 Rfree = 0.27|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/07 2014/10/16 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:RCCh4ZkVE2BITRjPSL38IKnaaAk9606 intact-crc:120E4E286D65C500|rigid:bsUTx7Fo/azlxRvUd6WLKyhNwXE false sufficient binding region:333-398 sufficient binding region:174-205 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00512 uniprotkb:Q9Y3Y4 intact:EBI-533127|uniprotkb:Q5T489|intact:EBI-28969406|ensembl:ENSP00000234739 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 psi-mi:bcl9_human(display_long)|uniprotkb:Protein legless homolog(gene name synonym)|uniprotkb:BCL9(gene name)|psi-mi:BCL9(display_short) psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fiedler et al. (2008) pubmed:18498752|imex:IM-17354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6142511|imex:IM-17354-1|rcsb pdb:2vp7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000234739|ensembl:ENSG00000116128(gene)|ensembl:ENST00000234739(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:O00512|rcsb pdb:2GL7|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|rcsb pdb:3SL9|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:NP_004317.2|refseq:XP_005273028.1 ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 - - - figure legend:Table 1 and 2|3d-resolution:1.65A|3d-r-factors:Rworking = 0.22 Rfree = 0.27|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/07 2014/10/16 rogid:RCCh4ZkVE2BITRjPSL38IKnaaAk9606 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 intact-crc:B36343E3E407951C|rigid:bsUTx7Fo/azlxRvUd6WLKyhNwXE false sufficient binding region:174-205 sufficient binding region:333-402|mutation:366-366 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3Y4 uniprotkb:O00512 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-533127|uniprotkb:Q5T489|intact:EBI-28969406|ensembl:ENSP00000234739 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:bcl9_human(display_long)|uniprotkb:Protein legless homolog(gene name synonym)|uniprotkb:BCL9(gene name)|psi-mi:BCL9(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fiedler et al. (2008) pubmed:18498752|imex:IM-17354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6142529|rcsb pdb:2vpb|imex:IM-17354-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 ensembl:ENSP00000234739|ensembl:ENSG00000116128(gene)|ensembl:ENST00000234739(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:O00512|rcsb pdb:2GL7|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|rcsb pdb:3SL9|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:NP_004317.2|refseq:XP_005273028.1 - - - figure legend:Table 1 and 2|3d-resolution:1.59A|3d-r-factors:Rworking = 0.19 Rfree = 0.23|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/07 2014/10/16 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:RCCh4ZkVE2BITRjPSL38IKnaaAk9606 intact-crc:798FE3418AD8064D|rigid:bsUTx7Fo/azlxRvUd6WLKyhNwXE false sufficient binding region:333-397 sufficient binding region:174-205 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00512 intact:EBI-6146769 intact:EBI-533127|uniprotkb:Q5T489|intact:EBI-28969406|ensembl:ENSP00000234739 - psi-mi:bcl9_human(display_long)|uniprotkb:Protein legless homolog(gene name synonym)|uniprotkb:BCL9(gene name)|psi-mi:BCL9(display_short) psi-mi:h3_peptide_fragment(display_short)|psi-mi:EBI-6146769(display_long) psi-mi:"MI:0114"(x-ray crystallography) Fiedler et al. (2008) pubmed:18498752|imex:IM-17354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6146771|imex:IM-17354-4|rcsb pdb:2vpe - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSP00000234739|ensembl:ENSG00000116128(gene)|ensembl:ENST00000234739(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:O00512|rcsb pdb:2GL7|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|rcsb pdb:3SL9|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:NP_004317.2|refseq:XP_005273028.1 - - - - figure legend:Table 1 and 2|3d-resolution:1.7A|3d-r-factors:Rworking = 0.19 Rfree = 0.23|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/07 2014/10/16 rogid:RCCh4ZkVE2BITRjPSL38IKnaaAk9606 rogid:LQsWmI6D2Fx80rIUtLsFd2iMGio9606 intact-crc:9416399FCE3BEF66|rigid:VM9mDfjRSEHAtvV7MvecylLWG1Q false sufficient binding region:177-205 - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00512 uniprotkb:Q9Y3Y4 intact:EBI-533127|uniprotkb:Q5T489|intact:EBI-28969406|ensembl:ENSP00000234739 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 psi-mi:bcl9_human(display_long)|uniprotkb:Protein legless homolog(gene name synonym)|uniprotkb:BCL9(gene name)|psi-mi:BCL9(display_short) psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fiedler et al. (2008) pubmed:18498752|imex:IM-17354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6146771|imex:IM-17354-4|rcsb pdb:2vpe - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000234739|ensembl:ENSG00000116128(gene)|ensembl:ENST00000234739(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:O00512|rcsb pdb:2GL7|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|rcsb pdb:3SL9|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:NP_004317.2|refseq:XP_005273028.1 ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 - - - figure legend:Table 1 and 2|3d-resolution:1.7A|3d-r-factors:Rworking = 0.19 Rfree = 0.23|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/07 2014/10/16 rogid:RCCh4ZkVE2BITRjPSL38IKnaaAk9606 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 intact-crc:9416399FCE3BEF66|rigid:VM9mDfjRSEHAtvV7MvecylLWG1Q false sufficient binding region:177-205 sufficient binding region:340-398 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00512 intact:EBI-6146769 intact:EBI-533127|uniprotkb:Q5T489|intact:EBI-28969406|ensembl:ENSP00000234739 - psi-mi:bcl9_human(display_long)|uniprotkb:Protein legless homolog(gene name synonym)|uniprotkb:BCL9(gene name)|psi-mi:BCL9(display_short) psi-mi:h3_peptide_fragment(display_short)|psi-mi:EBI-6146769(display_long) psi-mi:"MI:0114"(x-ray crystallography) Fiedler et al. (2008) pubmed:18498752|imex:IM-17354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6146783|imex:IM-17354-5|rcsb pdb:2vpg - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSP00000234739|ensembl:ENSG00000116128(gene)|ensembl:ENST00000234739(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:O00512|rcsb pdb:2GL7|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|rcsb pdb:3SL9|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:NP_004317.2|refseq:XP_005273028.1 - - - - figure legend:Table 1 and 2|3d-resolution:1.6A|3d-r-factors:Rworking = 0.2, Rfree = 0.22|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/07 2014/10/16 rogid:RCCh4ZkVE2BITRjPSL38IKnaaAk9606 rogid:LQsWmI6D2Fx80rIUtLsFd2iMGio9606 intact-crc:FCCC79F7D466B2B4|rigid:VM9mDfjRSEHAtvV7MvecylLWG1Q false sufficient binding region:177-205 - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00512 uniprotkb:Q9Y3Y4 intact:EBI-533127|uniprotkb:Q5T489|intact:EBI-28969406|ensembl:ENSP00000234739 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 psi-mi:bcl9_human(display_long)|uniprotkb:Protein legless homolog(gene name synonym)|uniprotkb:BCL9(gene name)|psi-mi:BCL9(display_short) psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fiedler et al. (2008) pubmed:18498752|imex:IM-17354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6146783|imex:IM-17354-5|rcsb pdb:2vpg - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000234739|ensembl:ENSG00000116128(gene)|ensembl:ENST00000234739(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:O00512|rcsb pdb:2GL7|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|rcsb pdb:3SL9|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:NP_004317.2|refseq:XP_005273028.1 ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 - - - figure legend:Table 1 and 2|3d-resolution:1.6A|3d-r-factors:Rworking = 0.2, Rfree = 0.22|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/07 2014/10/16 rogid:RCCh4ZkVE2BITRjPSL38IKnaaAk9606 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 intact-crc:FCCC79F7D466B2B4|rigid:VM9mDfjRSEHAtvV7MvecylLWG1Q false sufficient binding region:177-205 sufficient binding region:340-398 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q961D9 uniprotkb:Q9Y3Y4 intact:EBI-85519|uniprotkb:Q9V4D2|ensemblmetazoa:FBpp0088180 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 psi-mi:bcl9_drome(display_long)|uniprotkb:lgs(gene name)|psi-mi:lgs(display_short)|uniprotkb:BCL9(gene name synonym)|uniprotkb:CG2041(orf name)|uniprotkb:Protein legless(gene name synonym) psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:"MI:0096"(pull down) Fiedler et al. (2008) pubmed:18498752|imex:IM-17354 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6170828|wwpdb:2vp7|imex:IM-17354-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651922.1|flybase:FBgn0039907|ensemblmetazoa:FBgn0039907(gene)|ensemblmetazoa:FBtr0089111(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007491"(sternite morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0035223"(leg disc pattern formation)|rcsb pdb:3ZPV|reactome:R-DME-201722|reactome:R-DME-209407|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|reactome:R-DME-209421|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR024670|dip:DIP-33392N ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 - - - figure legend:Supp. Fig. 2B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/07 2014/10/16 rogid:W5+IVXO6J6D9E9N7P5R6tFQ7bpc7227 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 intact-crc:CB0937ACC1939C23|rigid:NibkIFPagO23I11hR4kxIOFEMhg false maltose binding protein tag:?-?|sufficient binding region:316-350 glutathione s tranferase tag:?-?|sufficient binding region:333-402 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y3Y4 uniprotkb:O00512 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-533127|uniprotkb:Q5T489|intact:EBI-28969406|ensembl:ENSP00000234739 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:bcl9_human(display_long)|uniprotkb:Protein legless homolog(gene name synonym)|uniprotkb:BCL9(gene name)|psi-mi:BCL9(display_short) psi-mi:"MI:0096"(pull down) Fiedler et al. (2008) pubmed:18498752|imex:IM-17354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6170787|wwpdb:2vp7|imex:IM-17354-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 ensembl:ENSP00000234739|ensembl:ENSG00000116128(gene)|ensembl:ENST00000234739(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:O00512|rcsb pdb:2GL7|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|rcsb pdb:3SL9|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:NP_004317.2|refseq:XP_005273028.1 - - - figure legend:Supp. Fig. 1A, 1D, 2A, 2B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/07 2014/10/16 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:RCCh4ZkVE2BITRjPSL38IKnaaAk9606 intact-crc:86704B1BF3092D47|rigid:bsUTx7Fo/azlxRvUd6WLKyhNwXE false sufficient binding region:333-402|glutathione s tranferase tag:?-? sufficient binding region:177-205|maltose binding protein tag:?-? - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O00512 uniprotkb:Q9Y3Y4 intact:EBI-533127|uniprotkb:Q5T489|intact:EBI-28969406|ensembl:ENSP00000234739 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 psi-mi:bcl9_human(display_long)|uniprotkb:Protein legless homolog(gene name synonym)|uniprotkb:BCL9(gene name)|psi-mi:BCL9(display_short) psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:"MI:0071"(molecular sieving) Fiedler et al. (2008) pubmed:18498752|imex:IM-17354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6170813|wwpdb:2vp7|imex:IM-17354-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000234739|ensembl:ENSG00000116128(gene)|ensembl:ENST00000234739(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:O00512|rcsb pdb:2GL7|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|rcsb pdb:3SL9|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:NP_004317.2|refseq:XP_005273028.1 ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 - - - figure legend:Supp. Fig. 1B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/07 2014/10/16 rogid:RCCh4ZkVE2BITRjPSL38IKnaaAk9606 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 intact-crc:45A9F1B9BF95DAB0|rigid:bsUTx7Fo/azlxRvUd6WLKyhNwXE false sufficient binding region:174-205 sufficient binding region:333-402 1 1 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)