#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P22518 uniprotkb:Q5ZRQ0 intact:EBI-6479117|uniprotkb:A6H6K2|uniprotkb:Q3UXB6|ensembl:ENSMUSP00000034868 intact:EBI-6402540|ensemblbacteria:AAU28878 psi-mi:clk1_mouse(display_long)|uniprotkb:Clk1(gene name)|psi-mi:Clk1(display_short)|uniprotkb:Clk(gene name synonym)|uniprotkb:Sty(gene name synonym)|uniprotkb:CDC-like kinase 1(gene name synonym)|uniprotkb:Protein kinase STY(gene name synonym) psi-mi:lubx_legph(display_long)|uniprotkb:Legionella U-box protein(gene name synonym)|uniprotkb:lubX(gene name)|psi-mi:lubX(display_short)|uniprotkb:legU2(gene name synonym)|uniprotkb:lpg2830(locus name)|uniprotkb:RING-type E3 ubiquitin transferase LubX(gene name synonym) psi-mi:"MI:0096"(pull down) Kubori et al. (2008) pubmed:18284575|imex:IM-18184 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6479302|mpidb:MPIDB-INT-1173|imex:IM-18184-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036099.1|ensembl:ENSMUSG00000026034(gene)|ensembl:ENSMUST00000034868(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P22518 ensemblbacteria:AAU28878(transcript)|ensemblbacteria:lpg2830(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043657"(host cell)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_096825.1|dip:DIP-59158N - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/30 2014/10/16 rogid:X8WBFAKvewkpwRj6GMc55rqWUzs10090 rogid:0bi5TdwZ5OeOhOowhQlpuRL34p4272624 intact-crc:F81B78AF312DEC3D|rigid:UAkiX5ftNvDb8d2Aa7o9NIbqpx8 false myc tag:?-?|his tag:?-? glutathione s tranferase tag:?-?|sufficient binding region:135..135-246(IPR003613) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P22518 uniprotkb:Q5ZRQ0 intact:EBI-6479117|uniprotkb:A6H6K2|uniprotkb:Q3UXB6|ensembl:ENSMUSP00000034868 intact:EBI-6402540|ensemblbacteria:AAU28878 psi-mi:clk1_mouse(display_long)|uniprotkb:Clk1(gene name)|psi-mi:Clk1(display_short)|uniprotkb:Clk(gene name synonym)|uniprotkb:Sty(gene name synonym)|uniprotkb:CDC-like kinase 1(gene name synonym)|uniprotkb:Protein kinase STY(gene name synonym) psi-mi:lubx_legph(display_long)|uniprotkb:Legionella U-box protein(gene name synonym)|uniprotkb:lubX(gene name)|psi-mi:lubX(display_short)|uniprotkb:legU2(gene name synonym)|uniprotkb:lpg2830(locus name)|uniprotkb:RING-type E3 ubiquitin transferase LubX(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kubori et al. (2008) pubmed:18284575|imex:IM-18184 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6402560|mpidb:MPIDB-INT-1173|imex:IM-18184-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036099.1|ensembl:ENSMUSG00000026034(gene)|ensembl:ENSMUST00000034868(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P22518 ensemblbacteria:AAU28878(transcript)|ensemblbacteria:lpg2830(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043657"(host cell)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_096825.1|dip:DIP-59158N - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2012/11/30 2014/10/16 rogid:X8WBFAKvewkpwRj6GMc55rqWUzs10090 rogid:0bi5TdwZ5OeOhOowhQlpuRL34p4272624 intact-crc:10EA1CB0EBAC6630|rigid:UAkiX5ftNvDb8d2Aa7o9NIbqpx8 false ha tag:?-? enhanced green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P22518 uniprotkb:Q5ZRQ0 intact:EBI-6479117|uniprotkb:A6H6K2|uniprotkb:Q3UXB6|ensembl:ENSMUSP00000034868 intact:EBI-6402540|ensemblbacteria:AAU28878 psi-mi:clk1_mouse(display_long)|uniprotkb:Clk1(gene name)|psi-mi:Clk1(display_short)|uniprotkb:Clk(gene name synonym)|uniprotkb:Sty(gene name synonym)|uniprotkb:CDC-like kinase 1(gene name synonym)|uniprotkb:Protein kinase STY(gene name synonym) psi-mi:lubx_legph(display_long)|uniprotkb:Legionella U-box protein(gene name synonym)|uniprotkb:lubX(gene name)|psi-mi:lubX(display_short)|uniprotkb:legU2(gene name synonym)|uniprotkb:lpg2830(locus name)|uniprotkb:RING-type E3 ubiquitin transferase LubX(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kubori et al. (2008) pubmed:18284575|imex:IM-18184 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6402551|mpidb:MPIDB-INT-1172|imex:IM-18184-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036099.1|ensembl:ENSMUSG00000026034(gene)|ensembl:ENSMUST00000034868(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P22518 ensemblbacteria:AAU28878(transcript)|ensemblbacteria:lpg2830(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043657"(host cell)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_096825.1|dip:DIP-59158N - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/30 2014/10/16 rogid:X8WBFAKvewkpwRj6GMc55rqWUzs10090 rogid:0bi5TdwZ5OeOhOowhQlpuRL34p4272624 intact-crc:B67F00E0765B73DF|rigid:UAkiX5ftNvDb8d2Aa7o9NIbqpx8 false - sufficient binding region:135..135-246(IPR003613)|mutation increasing interaction strength:45-45|sufficient binding region:1-221 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)