#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0A9Q1	uniprotkb:P02930	intact:EBI-1119939|uniprotkb:P03026|uniprotkb:Q2M5R6|ensemblbacteria:AAC77354|ensemblbacteria:BAE78390	intact:EBI-875614|uniprotkb:Q2M9G5|ensemblbacteria:AAC76071|ensemblbacteria:BAE77091	psi-mi:arca_ecoli(display_long)|uniprotkb:Dye resistance protein(gene name synonym)|uniprotkb:arcA(gene name)|psi-mi:arcA(display_short)|uniprotkb:cpxC(gene name synonym)|uniprotkb:dye(gene name synonym)|uniprotkb:fexA(gene name synonym)|uniprotkb:msp(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:sfrA(gene name synonym)|uniprotkb:b4401(locus name)|uniprotkb:JW4364(locus name)	psi-mi:tolc_ecoli(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:mtcB(gene name synonym)|uniprotkb:mukA(gene name synonym)|uniprotkb:refI(gene name synonym)|uniprotkb:Multidrug efflux pump subunit TolC(gene name synonym)|uniprotkb:Outer membrane factor TolC(gene name synonym)|uniprotkb:colE1-i(gene name synonym)|uniprotkb:toc(gene name synonym)|uniprotkb:weeA(gene name synonym)|uniprotkb:JW5503(locus name)|uniprotkb:b3035(locus name)	psi-mi:"MI:0030"(cross-linking study)	Krishnamoorthy et al. (2008)	pubmed:18024521|imex:IM-18160	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6401352|mpidb:MPIDB-INT-973|imex:IM-18160-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001194358.1|ensemblbacteria:AAC77354(transcript)|ensemblbacteria:b4401(gene)|ensemblbacteria:BAE78390(gene)|ensemblbacteria:BAE78390(transcript)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR011006(CheY-like)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR036388|interpro:IPR039420|rcsb pdb:1XHE|rcsb pdb:1XHF|refseq:NP_418818.1|dip:DIP-36035N	refseq:NP_417507.2|refseq:WP_000735278.1|dip:DIP-11007N|ensemblbacteria:AAC76071(transcript)|ensemblbacteria:b3035(gene)|ensemblbacteria:BAE77091(gene)|ensemblbacteria:BAE77091(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0009279"(cell outer membrane)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042930"(enterobactin transport)|go:"GO:0045203"(integral component of cell outer membrane)|go:"GO:0046677"(response to antibiotic)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|interpro:IPR010130(Type I secretion outer membrane protein, TolC)|rcsb pdb:1EK9|rcsb pdb:1TQQ|rcsb pdb:2VDD|rcsb pdb:2VDE|rcsb pdb:2WMZ|rcsb pdb:2XMN|rcsb pdb:5NG5|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5O66|rcsb pdb:5V5S|rcsb pdb:6WXH|rcsb pdb:6WXI	-	-	-	figure legend:Figs. 1B, 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/11/30	2014/10/16	rogid:vs/0hfefwjUoJlsF4GnmqWWUJY883333	rogid:67LQDsYiAt6tDwigzlhM3Pp5+JA83333	intact-crc:4C741D594AE9B62A|rigid:GetLy9HciWV2rZLisT7I5Kz7qww	false	his tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0A9Q1	uniprotkb:P52002	intact:EBI-1119939|uniprotkb:P03026|uniprotkb:Q2M5R6|ensemblbacteria:AAC77354|ensemblbacteria:BAE78390	intact:EBI-6400435|ensemblbacteria:AAG03815|uniprotkb:Q9S505	psi-mi:arca_ecoli(display_long)|uniprotkb:Dye resistance protein(gene name synonym)|uniprotkb:arcA(gene name)|psi-mi:arcA(display_short)|uniprotkb:cpxC(gene name synonym)|uniprotkb:dye(gene name synonym)|uniprotkb:fexA(gene name synonym)|uniprotkb:msp(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:sfrA(gene name synonym)|uniprotkb:b4401(locus name)|uniprotkb:JW4364(locus name)	psi-mi:mexb_pseae(display_long)|uniprotkb:Multidrug-efflux transporter MexB(gene name synonym)|uniprotkb:PA0426(locus name)|uniprotkb:mexB(gene name)|psi-mi:mexB(display_short)	psi-mi:"MI:0030"(cross-linking study)	Krishnamoorthy et al. (2008)	pubmed:18024521|imex:IM-18160	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6401352|mpidb:MPIDB-INT-973|imex:IM-18160-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001194358.1|ensemblbacteria:AAC77354(transcript)|ensemblbacteria:b4401(gene)|ensemblbacteria:BAE78390(gene)|ensemblbacteria:BAE78390(transcript)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR011006(CheY-like)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR036388|interpro:IPR039420|rcsb pdb:1XHE|rcsb pdb:1XHF|refseq:NP_418818.1|dip:DIP-36035N	ensemblbacteria:AAG03815(transcript)|ensemblbacteria:PA0426(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR004764(Hydrophobe/amphiphile efflux-1 HAE1)|interpro:IPR027463|rcsb pdb:2V50|rcsb pdb:3W9I|rcsb pdb:3W9J|rcsb pdb:6IIA|rcsb pdb:6IOK|rcsb pdb:6IOL|rcsb pdb:6T7S|rcsb pdb:6TA5|rcsb pdb:6TA6|refseq:NP_249117.1|refseq:WP_003107312.1|dip:DIP-60510N	-	-	-	figure legend:Figs. 1B, 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/11/30	2014/10/16	rogid:vs/0hfefwjUoJlsF4GnmqWWUJY883333	rogid:uRtmabVKHE9WHJKQxQmpG6LiQkg208964	intact-crc:4C741D594AE9B62A|rigid:GetLy9HciWV2rZLisT7I5Kz7qww	false	his tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0A9Q1	uniprotkb:P52002	intact:EBI-1119939|uniprotkb:P03026|uniprotkb:Q2M5R6|ensemblbacteria:AAC77354|ensemblbacteria:BAE78390	intact:EBI-6400435|ensemblbacteria:AAG03815|uniprotkb:Q9S505	psi-mi:arca_ecoli(display_long)|uniprotkb:Dye resistance protein(gene name synonym)|uniprotkb:arcA(gene name)|psi-mi:arcA(display_short)|uniprotkb:cpxC(gene name synonym)|uniprotkb:dye(gene name synonym)|uniprotkb:fexA(gene name synonym)|uniprotkb:msp(gene name synonym)|uniprotkb:seg(gene name synonym)|uniprotkb:sfrA(gene name synonym)|uniprotkb:b4401(locus name)|uniprotkb:JW4364(locus name)	psi-mi:mexb_pseae(display_long)|uniprotkb:Multidrug-efflux transporter MexB(gene name synonym)|uniprotkb:PA0426(locus name)|uniprotkb:mexB(gene name)|psi-mi:mexB(display_short)	psi-mi:"MI:0030"(cross-linking study)	Krishnamoorthy et al. (2008)	pubmed:18024521|imex:IM-18160	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6401347|mpidb:MPIDB-INT-974|imex:IM-18160-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001194358.1|ensemblbacteria:AAC77354(transcript)|ensemblbacteria:b4401(gene)|ensemblbacteria:BAE78390(gene)|ensemblbacteria:BAE78390(transcript)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR011006(CheY-like)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR036388|interpro:IPR039420|rcsb pdb:1XHE|rcsb pdb:1XHF|refseq:NP_418818.1|dip:DIP-36035N	ensemblbacteria:AAG03815(transcript)|ensemblbacteria:PA0426(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR004764(Hydrophobe/amphiphile efflux-1 HAE1)|interpro:IPR027463|rcsb pdb:2V50|rcsb pdb:3W9I|rcsb pdb:3W9J|rcsb pdb:6IIA|rcsb pdb:6IOK|rcsb pdb:6IOL|rcsb pdb:6T7S|rcsb pdb:6TA5|rcsb pdb:6TA6|refseq:NP_249117.1|refseq:WP_003107312.1|dip:DIP-60510N	-	-	-	figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/11/30	2014/10/16	rogid:vs/0hfefwjUoJlsF4GnmqWWUJY883333	rogid:uRtmabVKHE9WHJKQxQmpG6LiQkg208964	intact-crc:24AC967A1B167FC1|rigid:VcNyW2G/SD/CCPOXt0XJXrAg7vc	false	his tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)