#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6AYI1	uniprotkb:Q08775	intact:EBI-931635|ensembl:ENSRNOP00000041663	intact:EBI-903354|uniprotkb:O35183|uniprotkb:Q08776|uniprotkb:Q9JLN0|uniprotkb:Q9QUQ6|uniprotkb:Q9QY29|uniprotkb:Q9R0U4|uniprotkb:Q9Z2J7	psi-mi:q6ayi1_rat(display_long)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Probable ATP-dependent RNA helicase DDX5(gene name synonym)|uniprotkb:rCG_35034(orf name)	psi-mi:runx2_mouse(display_long)|uniprotkb:Runx2(gene name)|psi-mi:Runx2(display_short)|uniprotkb:Aml3(gene name synonym)|uniprotkb:Cbfa1(gene name synonym)|uniprotkb:Osf2(gene name synonym)|uniprotkb:Pebp2a(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Jensen et al. (2008)	pubmed:17960593|imex:IM-17316	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6119912|imex:IM-17316-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:619906|refseq:NP_001007614.1|refseq:XP_008766535.1|ensembl:ENSRNOG00000030680(gene)|ensembl:ENSRNOT00000048490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-RNO-3899300|reactome:R-RNO-72163|reactome:R-RNO-9018519	refseq:NP_001139510.1|refseq:NP_033950.2|refseq:NP_001258556.1|refseq:XP_006523607.1|refseq:XP_006523608.1|mint:Q08775|dip:DIP-36316N|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR027384|reactome:R-MMU-8878166|reactome:R-MMU-8939902|reactome:R-MMU-8940973|reactome:R-MMU-8941326|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)	-	-	-	figure legend:3A and B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-umr-106)|taxid:10116(Rattus norvegicus)	-	2012/05/04	2014/10/16	rogid:MiLWQ8hublA83RxlL984FW1wYNk10116	rogid:WYs7JxHzJasUS7fx5/LzgKJEjEY10090	intact-crc:08255FB8A8A97AD1|rigid:Z7aA289U0mdO1am1qKVPq37y8tk	false	-	calmodulin binding peptide plus protein a tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08775	uniprotkb:F1LR10	intact:EBI-903354|uniprotkb:O35183|uniprotkb:Q08776|uniprotkb:Q9JLN0|uniprotkb:Q9QUQ6|uniprotkb:Q9QY29|uniprotkb:Q9R0U4|uniprotkb:Q9Z2J7	intact:EBI-6119883|uniprotkb:G3V8I6|ensembl:ENSRNOP00000072604	psi-mi:runx2_mouse(display_long)|uniprotkb:Runx2(gene name)|psi-mi:Runx2(display_short)|uniprotkb:Aml3(gene name synonym)|uniprotkb:Cbfa1(gene name synonym)|uniprotkb:Osf2(gene name synonym)|uniprotkb:Pebp2a(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)	psi-mi:lima1_rat(display_long)|uniprotkb:Epithelial protein lost in neoplasm(gene name synonym)|uniprotkb:Lima1(gene name)|psi-mi:Lima1(display_short)|uniprotkb:eplin(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Jensen et al. (2008)	pubmed:17960593|imex:IM-17316	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6119895|imex:IM-17316-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139510.1|refseq:NP_033950.2|refseq:NP_001258556.1|refseq:XP_006523607.1|refseq:XP_006523608.1|mint:Q08775|dip:DIP-36316N|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR027384|reactome:R-MMU-8878166|reactome:R-MMU-8939902|reactome:R-MMU-8940973|reactome:R-MMU-8941326|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)	refseq:NP_001178544.1|refseq:XP_006257417.1|rgd:1564050|ensembl:ENSRNOG00000059801(gene)|ensembl:ENSRNOT00000091702(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031526"(brush border membrane)|go:"GO:0031529"(ruffle organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028740	-	-	-	figure legend:2B|comment:"Also co-purified but could not be mapped to proteins: alpha-actinin and HSP70"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-umr-106)|taxid:10116(Rattus norvegicus)	-	2012/05/04	2014/10/16	rogid:WYs7JxHzJasUS7fx5/LzgKJEjEY10090	rogid:1/LYc7TSjv8XmmHXu7tPVnsRHqY10116	intact-crc:79A7E28B5EA71282|rigid:8SdY/CY0zUjvLu3FAF2rSmCGQEc	false	calmodulin binding peptide plus protein a tag:n-n	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q08775	uniprotkb:Q68FP1	intact:EBI-903354|uniprotkb:O35183|uniprotkb:Q08776|uniprotkb:Q9JLN0|uniprotkb:Q9QUQ6|uniprotkb:Q9QY29|uniprotkb:Q9R0U4|uniprotkb:Q9Z2J7	intact:EBI-6096401|ensembl:ENSRNOP00000025857	psi-mi:runx2_mouse(display_long)|uniprotkb:Runx2(gene name)|psi-mi:Runx2(display_short)|uniprotkb:Aml3(gene name synonym)|uniprotkb:Cbfa1(gene name synonym)|uniprotkb:Osf2(gene name synonym)|uniprotkb:Pebp2a(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)	psi-mi:gels_rat(display_long)|uniprotkb:Gsn(gene name)|psi-mi:Gsn(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Jensen et al. (2008)	pubmed:17960593|imex:IM-17316	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6119895|imex:IM-17316-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139510.1|refseq:NP_033950.2|refseq:NP_001258556.1|refseq:XP_006523607.1|refseq:XP_006523608.1|mint:Q08775|dip:DIP-36316N|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR027384|reactome:R-MMU-8878166|reactome:R-MMU-8939902|reactome:R-MMU-8940973|reactome:R-MMU-8941326|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)	rgd:1303089|refseq:NP_001004080.1|refseq:XP_006234102.1|ensembl:ENSRNOG00000018991(gene)|ensembl:ENSRNOT00000025857(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043209"(myelin sheath)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051593"(response to folic acid)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:Q68FP1|reactome:R-RNO-264870|reactome:R-RNO-6798695|go:"GO:0045471"(response to ethanol)	-	-	-	figure legend:2B|comment:"Also co-purified but could not be mapped to proteins: alpha-actinin and HSP70"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-umr-106)|taxid:10116(Rattus norvegicus)	-	2012/05/04	2014/10/16	rogid:WYs7JxHzJasUS7fx5/LzgKJEjEY10090	rogid:VEJohA79kwmQ8WB+zZ5DO5Wjw1g10116	intact-crc:79A7E28B5EA71282|rigid:8SdY/CY0zUjvLu3FAF2rSmCGQEc	false	calmodulin binding peptide plus protein a tag:n-n	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q08775	uniprotkb:Q6MG76	intact:EBI-903354|uniprotkb:O35183|uniprotkb:Q08776|uniprotkb:Q9JLN0|uniprotkb:Q9QUQ6|uniprotkb:Q9QY29|uniprotkb:Q9R0U4|uniprotkb:Q9Z2J7	intact:EBI-918873|uniprotkb:F1LP39	psi-mi:runx2_mouse(display_long)|uniprotkb:Runx2(gene name)|psi-mi:Runx2(display_short)|uniprotkb:Aml3(gene name synonym)|uniprotkb:Cbfa1(gene name synonym)|uniprotkb:Osf2(gene name synonym)|uniprotkb:Pebp2a(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)	psi-mi:q6mg76_rat(display_long)|uniprotkb:Apom(gene name synonym)|uniprotkb:Bat4(gene name synonym)|uniprotkb:C2(gene name synonym)|uniprotkb:C4a(gene name synonym)|uniprotkb:Cfb(gene name synonym)|uniprotkb:Csnk2b(gene name synonym)|uniprotkb:G7e(gene name synonym)|uniprotkb:Hspa1a(gene name synonym)|uniprotkb:Hspa1b(gene name synonym)|uniprotkb:Ly6g5c(gene name synonym)|uniprotkb:Ly6g6c(gene name synonym)|uniprotkb:Neu1(gene name synonym)|uniprotkb:Ng35(gene name synonym)|uniprotkb:Rps25-ps2(gene name synonym)|uniprotkb:Skiv2l(gene name)|psi-mi:Skiv2l(display_short)|uniprotkb:Hspa1l(gene name synonym)|uniprotkb:Stk19(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Jensen et al. (2008)	pubmed:17960593|imex:IM-17316	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6119895|imex:IM-17316-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139510.1|refseq:NP_033950.2|refseq:NP_001258556.1|refseq:XP_006523607.1|refseq:XP_006523608.1|mint:Q08775|dip:DIP-36316N|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR027384|reactome:R-MMU-8878166|reactome:R-MMU-8939902|reactome:R-MMU-8940973|reactome:R-MMU-8941326|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)	rgd:1303059|refseq:NP_998724.1|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR040801|interpro:IPR025696|interpro:IPR027417|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0055087"(Ski complex)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)	-	-	-	figure legend:2B|comment:"Also co-purified but could not be mapped to proteins: alpha-actinin and HSP70"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-umr-106)|taxid:10116(Rattus norvegicus)	-	2012/05/04	2014/10/16	rogid:WYs7JxHzJasUS7fx5/LzgKJEjEY10090	rogid:IJS09dBklrDhfh6+HDNEfsTBwbI10116	intact-crc:79A7E28B5EA71282|rigid:8SdY/CY0zUjvLu3FAF2rSmCGQEc	false	calmodulin binding peptide plus protein a tag:n-n	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q08775	uniprotkb:Q6AYI1	intact:EBI-903354|uniprotkb:O35183|uniprotkb:Q08776|uniprotkb:Q9JLN0|uniprotkb:Q9QUQ6|uniprotkb:Q9QY29|uniprotkb:Q9R0U4|uniprotkb:Q9Z2J7	intact:EBI-931635|ensembl:ENSRNOP00000041663	psi-mi:runx2_mouse(display_long)|uniprotkb:Runx2(gene name)|psi-mi:Runx2(display_short)|uniprotkb:Aml3(gene name synonym)|uniprotkb:Cbfa1(gene name synonym)|uniprotkb:Osf2(gene name synonym)|uniprotkb:Pebp2a(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)	psi-mi:q6ayi1_rat(display_long)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Probable ATP-dependent RNA helicase DDX5(gene name synonym)|uniprotkb:rCG_35034(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Jensen et al. (2008)	pubmed:17960593|imex:IM-17316	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6119895|imex:IM-17316-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139510.1|refseq:NP_033950.2|refseq:NP_001258556.1|refseq:XP_006523607.1|refseq:XP_006523608.1|mint:Q08775|dip:DIP-36316N|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR027384|reactome:R-MMU-8878166|reactome:R-MMU-8939902|reactome:R-MMU-8940973|reactome:R-MMU-8941326|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)	rgd:619906|refseq:NP_001007614.1|refseq:XP_008766535.1|ensembl:ENSRNOG00000030680(gene)|ensembl:ENSRNOT00000048490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-RNO-3899300|reactome:R-RNO-72163|reactome:R-RNO-9018519	-	-	-	figure legend:2B|comment:"Also co-purified but could not be mapped to proteins: alpha-actinin and HSP70"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-umr-106)|taxid:10116(Rattus norvegicus)	-	2012/05/04	2014/10/16	rogid:WYs7JxHzJasUS7fx5/LzgKJEjEY10090	rogid:MiLWQ8hublA83RxlL984FW1wYNk10116	intact-crc:79A7E28B5EA71282|rigid:8SdY/CY0zUjvLu3FAF2rSmCGQEc	false	calmodulin binding peptide plus protein a tag:n-n	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q08775	uniprotkb:Q568Z8	intact:EBI-903354|uniprotkb:O35183|uniprotkb:Q08776|uniprotkb:Q9JLN0|uniprotkb:Q9QUQ6|uniprotkb:Q9QY29|uniprotkb:Q9R0U4|uniprotkb:Q9Z2J7	intact:EBI-931649	psi-mi:runx2_mouse(display_long)|uniprotkb:Runx2(gene name)|psi-mi:Runx2(display_short)|uniprotkb:Aml3(gene name synonym)|uniprotkb:Cbfa1(gene name synonym)|uniprotkb:Osf2(gene name synonym)|uniprotkb:Pebp2a(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)	psi-mi:q568z8_rat(display_long)|uniprotkb:Ddx17(gene name)|psi-mi:Ddx17(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Jensen et al. (2008)	pubmed:17960593|imex:IM-17316	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6119895|imex:IM-17316-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139510.1|refseq:NP_033950.2|refseq:NP_001258556.1|refseq:XP_006523607.1|refseq:XP_006523608.1|mint:Q08775|dip:DIP-36316N|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR027384|reactome:R-MMU-8878166|reactome:R-MMU-8939902|reactome:R-MMU-8940973|reactome:R-MMU-8941326|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)	interpro:IPR001650(DNA/RNA helicase, C-terminal)|rgd:1304945|refseq:NP_001015018.1|interpro:IPR027417|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061614"(miRNA transcription)|go:"GO:0106222"(lncRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)	-	-	-	figure legend:2B|comment:"Also co-purified but could not be mapped to proteins: alpha-actinin and HSP70"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-umr-106)|taxid:10116(Rattus norvegicus)	-	2012/05/04	2014/10/16	rogid:WYs7JxHzJasUS7fx5/LzgKJEjEY10090	rogid:5tVye+AuW+xX7yJtYXSOIGllD2k10116	intact-crc:79A7E28B5EA71282|rigid:8SdY/CY0zUjvLu3FAF2rSmCGQEc	false	calmodulin binding peptide plus protein a tag:n-n	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q08775	uniprotkb:P17844	intact:EBI-903354|uniprotkb:O35183|uniprotkb:Q08776|uniprotkb:Q9JLN0|uniprotkb:Q9QUQ6|uniprotkb:Q9QY29|uniprotkb:Q9R0U4|uniprotkb:Q9Z2J7	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794	psi-mi:runx2_mouse(display_long)|uniprotkb:Runx2(gene name)|psi-mi:Runx2(display_short)|uniprotkb:Aml3(gene name synonym)|uniprotkb:Cbfa1(gene name synonym)|uniprotkb:Osf2(gene name synonym)|uniprotkb:Pebp2a(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Jensen et al. (2008)	pubmed:17960593|imex:IM-17316	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6119929|imex:IM-17316-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001139510.1|refseq:NP_033950.2|refseq:NP_001258556.1|refseq:XP_006523607.1|refseq:XP_006523608.1|mint:Q08775|dip:DIP-36316N|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR027384|reactome:R-MMU-8878166|reactome:R-MMU-8939902|reactome:R-MMU-8940973|reactome:R-MMU-8941326|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)	refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene)	go:"GO:0005634"(nucleus)	-	-	figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast)	-	2012/05/04	2014/10/16	rogid:WYs7JxHzJasUS7fx5/LzgKJEjEY10090	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	intact-crc:51D87B4BC022478D|rigid:WcKsaijueUGtiBSZ16GR3cWk68Q	false	-	tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9Z2J9	uniprotkb:Q6AYI1	intact:EBI-6119952|uniprotkb:Q99NC7	intact:EBI-931635|ensembl:ENSRNOP00000041663	psi-mi:runx2_rat(display_long)|uniprotkb:Runx2(gene name)|psi-mi:Runx2(display_short)|uniprotkb:Cbfa1(gene name synonym)|uniprotkb:Osf2(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)	psi-mi:q6ayi1_rat(display_long)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Probable ATP-dependent RNA helicase DDX5(gene name synonym)|uniprotkb:rCG_35034(orf name)	psi-mi:"MI:0663"(confocal microscopy)	Jensen et al. (2008)	pubmed:17960593|imex:IM-17316	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6119976|imex:IM-17316-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2282|dip:DIP-60266N|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")	rgd:619906|refseq:NP_001007614.1|refseq:XP_008766535.1|ensembl:ENSRNOG00000030680(gene)|ensembl:ENSRNOT00000048490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-RNO-3899300|reactome:R-RNO-72163|reactome:R-RNO-9018519	-	-	-	figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-ros17/2.8)|taxid:10116(Rattus norvegicus ROS17/2.8 osteosarcoma cell line)	-	2012/05/04	2014/10/16	rogid:WiQMKivXqKLl3yjKpGESq97pnzQ10116	rogid:MiLWQ8hublA83RxlL984FW1wYNk10116	intact-crc:6F42C8CB34588965|rigid:LNyCQJn4bW45CEuDU+zGRrZmYUs	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q08775-3	uniprotkb:P17844	intact:EBI-6119991	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794	psi-mi:q08775-3(display_long)|uniprotkb:PEBP2-alpha A1(isoform synonym)|uniprotkb:Runx2(gene name)|psi-mi:Runx2(display_short)|uniprotkb:Aml3(gene name synonym)|uniprotkb:Cbfa1(gene name synonym)|uniprotkb:Osf2(gene name synonym)|uniprotkb:Pebp2a(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jensen et al. (2008)	pubmed:17960593|imex:IM-17316	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6119989|imex:IM-17316-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-903354(isoform-parent)	refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene)	-	-	-	figure legend:3E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/04	2014/10/16	rogid:tiFzkScNY2PhNVE8uXPwt0StExc10090	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	intact-crc:FE3173D063285DB8|rigid:EzUAo96PoMR05hBo3JjRupua4D8	false	necessary binding region:1-383|glutathione s tranferase tag:?-?	necessary binding region:478-614|tag:?-?|35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P17844	uniprotkb:Q08775-3	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794	intact:EBI-6119991	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:q08775-3(display_long)|uniprotkb:PEBP2-alpha A1(isoform synonym)|uniprotkb:Runx2(gene name)|psi-mi:Runx2(display_short)|uniprotkb:Aml3(gene name synonym)|uniprotkb:Cbfa1(gene name synonym)|uniprotkb:Osf2(gene name synonym)|uniprotkb:Pebp2a(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jensen et al. (2008)	pubmed:17960593|imex:IM-17316	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6120012|imex:IM-17316-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene)	intact:EBI-903354(isoform-parent)	-	-	-	figure legend:3F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/05/04	2014/10/16	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	rogid:tiFzkScNY2PhNVE8uXPwt0StExc10090	intact-crc:024A84C452C732BB|rigid:EzUAo96PoMR05hBo3JjRupua4D8	false	glutathione s tranferase tag:?-?|necessary binding region:478-614	ha tag:?-?|35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)