#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:C3VHN8 uniprotkb:C3VHN8 intact:EBI-6400583 intact:EBI-6400583 psi-mi:c3vhn8_vibvl(display_long)|uniprotkb:vvpE(gene name)|psi-mi:vvpE(display_short) psi-mi:c3vhn8_vibvl(display_long)|uniprotkb:vvpE(gene name)|psi-mi:vvpE(display_short) psi-mi:"MI:0435"(protease assay) Chang et al. (2007) pubmed:17644589|imex:IM-18139 taxid:672(vibvl)|taxid:672(Vibrio vulnificus) taxid:672(vibvl)|taxid:672(Vibrio vulnificus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0903"(mpidb) intact:EBI-6464114|mpidb:MPIDB-INT-1064|imex:IM-18139-2 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0046872"(metal ion binding)|interpro:IPR001570(Peptidase M4, thermolysin C-terminal)|interpro:IPR007280(Peptidase, archaeal and bacterial C-terminal)|interpro:IPR011096(Propeptide, peptidase M4 and M36)|interpro:IPR013856(Peptidase M4, thermolysin)|interpro:IPR023612|interpro:IPR025711|interpro:IPR027268|refseq:WP_043877592.1 go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0046872"(metal ion binding)|interpro:IPR001570(Peptidase M4, thermolysin C-terminal)|interpro:IPR007280(Peptidase, archaeal and bacterial C-terminal)|interpro:IPR011096(Propeptide, peptidase M4 and M36)|interpro:IPR013856(Peptidase M4, thermolysin)|interpro:IPR023612|interpro:IPR025711|interpro:IPR027268|refseq:WP_043877592.1 go:"GO:0008237"(metallopeptidase activity)|go:"GO:0030163"(protein catabolic process) - - figure legend:Fig. 6, 7|comment:The N-terminal propeptide inhibited the activities of both the mature protease plus the C-terminal propeptide, and only the mature protease but this could not be fully captured as the substrate used for assessing protease activity was a mixture of proteins.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/30 2014/10/16 rogid:VgOvg8Vl67onpqCC5xurFLSefDA672 rogid:VgOvg8Vl67onpqCC5xurFLSefDA672 intact-crc:FE7136FD3853A621|rigid:kdFlzBVaB4I24OB4UsoxUpEI7Vk false sufficient binding region:198-514 his tag:?-?|sufficient binding region:25-197 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)