#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A7BFV9 uniprotkb:Q8VD37 intact:EBI-6095043 intact:EBI-776269|uniprotkb:A7BFW0|uniprotkb:Q3UFU3|uniprotkb:Q3UGA0|uniprotkb:Q8BXX4|uniprotkb:Q8C034|uniprotkb:Q9CXT2|ensembl:ENSMUSP00000079553 psi-mi:a7bfv9_rat(display_long) psi-mi:sgip1_mouse(display_long)|uniprotkb:Endophilin-3-interacting protein(gene name synonym)|uniprotkb:Sgip1(gene name)|psi-mi:Sgip1(display_short) psi-mi:"MI:0018"(two hybrid) Uezu et al. (2007) pubmed:17626015 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6116103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:A7BFV9|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR003903(Ubiquitin interacting motif)|go:"GO:0005509"(calcium ion binding) refseq:NP_659155.1|refseq:NP_001272788.1|refseq:NP_001272789.1|refseq:NP_001272791.1|refseq:XP_006503491.1|refseq:XP_017175890.1|ensembl:ENSMUSG00000028524(gene)|ensembl:ENSMUST00000080728(transcript)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098793"(presynapse)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR018808|interpro:IPR028565|interpro:IPR036168|interpro:IPR037984|mint:Q8VD37|reactome:R-MMU-8856825|reactome:R-MMU-8856828 - - - figure legend:fig 4A|curation depth:mimix curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/03 2014/10/16 rogid:R3E+FrsPBjI+M4QkNZ8lboaInKw10116 rogid:5TUgNAM4+5qY6EfbMvqhjc/i3/U10090 intact-crc:F4F22B3ADE32B559|rigid:jawkboaJ+NCfDNJp9WJvUOMnJYk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A7BFV9 uniprotkb:Q8VD37 intact:EBI-6095043 intact:EBI-776269|uniprotkb:A7BFW0|uniprotkb:Q3UFU3|uniprotkb:Q3UGA0|uniprotkb:Q8BXX4|uniprotkb:Q8C034|uniprotkb:Q9CXT2|ensembl:ENSMUSP00000079553 psi-mi:a7bfv9_rat(display_long) psi-mi:sgip1_mouse(display_long)|uniprotkb:Endophilin-3-interacting protein(gene name synonym)|uniprotkb:Sgip1(gene name)|psi-mi:Sgip1(display_short) psi-mi:"MI:0096"(pull down) Uezu et al. (2007) pubmed:17626015 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-6116261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:A7BFV9|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR003903(Ubiquitin interacting motif)|go:"GO:0005509"(calcium ion binding) refseq:NP_659155.1|refseq:NP_001272788.1|refseq:NP_001272789.1|refseq:NP_001272791.1|refseq:XP_006503491.1|refseq:XP_017175890.1|ensembl:ENSMUSG00000028524(gene)|ensembl:ENSMUST00000080728(transcript)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098793"(presynapse)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR018808|interpro:IPR028565|interpro:IPR036168|interpro:IPR037984|mint:Q8VD37|reactome:R-MMU-8856825|reactome:R-MMU-8856828 - - - figure legend:fig 4B|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/03 2014/10/16 rogid:R3E+FrsPBjI+M4QkNZ8lboaInKw10116 rogid:5TUgNAM4+5qY6EfbMvqhjc/i3/U10090 intact-crc:4C18B783255D9889|rigid:jawkboaJ+NCfDNJp9WJvUOMnJYk false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q8VD37 uniprotkb:P42567 intact:EBI-776269|uniprotkb:A7BFW0|uniprotkb:Q3UFU3|uniprotkb:Q3UGA0|uniprotkb:Q8BXX4|uniprotkb:Q8C034|uniprotkb:Q9CXT2|ensembl:ENSMUSP00000079553 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:sgip1_mouse(display_long)|uniprotkb:Endophilin-3-interacting protein(gene name synonym)|uniprotkb:Sgip1(gene name)|psi-mi:Sgip1(display_short) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Uezu et al. (2007) pubmed:17626015 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6116281 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659155.1|refseq:NP_001272788.1|refseq:NP_001272789.1|refseq:NP_001272791.1|refseq:XP_006503491.1|refseq:XP_017175890.1|ensembl:ENSMUSG00000028524(gene)|ensembl:ENSMUST00000080728(transcript)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098793"(presynapse)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR018808|interpro:IPR028565|interpro:IPR036168|interpro:IPR037984|mint:Q8VD37|reactome:R-MMU-8856825|reactome:R-MMU-8856828 ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N - - - figure legend:fig 4C|curation depth:mimix curation taxid:10090(mouse-n1e-115)|taxid:10090(Mus musculus neuroblastoma cells) - 2012/05/03 2014/10/16 rogid:5TUgNAM4+5qY6EfbMvqhjc/i3/U10090 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:C015EF96ED2FEB03|rigid:RJzX2Z97Nm0qWuq3N2F0oCB7IXo false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8VD37 uniprotkb:P17426 intact:EBI-776269|uniprotkb:A7BFW0|uniprotkb:Q3UFU3|uniprotkb:Q3UGA0|uniprotkb:Q8BXX4|uniprotkb:Q8C034|uniprotkb:Q9CXT2|ensembl:ENSMUSP00000079553 intact:EBI-775189|ensembl:ENSMUSP00000082519|ensembl:ENSMUSP00000127842 psi-mi:sgip1_mouse(display_long)|uniprotkb:Endophilin-3-interacting protein(gene name synonym)|uniprotkb:Sgip1(gene name)|psi-mi:Sgip1(display_short) psi-mi:ap2a1_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Ap2a1(gene name)|psi-mi:Ap2a1(display_short)|uniprotkb:Adtaa(gene name synonym)|uniprotkb:Clapa1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Uezu et al. (2007) pubmed:17626015 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6116281 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659155.1|refseq:NP_001272788.1|refseq:NP_001272789.1|refseq:NP_001272791.1|refseq:XP_006503491.1|refseq:XP_017175890.1|ensembl:ENSMUSG00000028524(gene)|ensembl:ENSMUST00000080728(transcript)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098793"(presynapse)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR018808|interpro:IPR028565|interpro:IPR036168|interpro:IPR037984|mint:Q8VD37|reactome:R-MMU-8856825|reactome:R-MMU-8856828 refseq:NP_001070732.1|refseq:NP_031484.1|ensembl:ENSMUSG00000060279(gene)|ensembl:ENSMUST00000085399(transcript)|ensembl:ENSMUST00000166972(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0032433"(filopodium tip)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17426|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038 - - - figure legend:fig 4C|curation depth:mimix curation taxid:10090(mouse-n1e-115)|taxid:10090(Mus musculus neuroblastoma cells) - 2012/05/03 2014/10/16 rogid:5TUgNAM4+5qY6EfbMvqhjc/i3/U10090 rogid:Dd6Q+Et/LTlmo5qpro2Zaeq0dMc10090 intact-crc:C015EF96ED2FEB03|rigid:RJzX2Z97Nm0qWuq3N2F0oCB7IXo false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P17426 uniprotkb:P42567 intact:EBI-775189|ensembl:ENSMUSP00000082519|ensembl:ENSMUSP00000127842 intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431 psi-mi:ap2a1_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Ap2a1(gene name)|psi-mi:Ap2a1(display_short)|uniprotkb:Adtaa(gene name synonym)|uniprotkb:Clapa1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym) psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short) psi-mi:"MI:0663"(confocal microscopy) Uezu et al. (2007) pubmed:17626015 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6116308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070732.1|refseq:NP_031484.1|ensembl:ENSMUSG00000060279(gene)|ensembl:ENSMUST00000085399(transcript)|ensembl:ENSMUST00000166972(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0032433"(filopodium tip)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17426|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038 ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N - - - figure legend:fig 5|curation depth:mimix curation taxid:10090(mouse-n1e-115)|taxid:10090(Mus musculus neuroblastoma cells) - 2012/05/03 2014/10/16 rogid:Dd6Q+Et/LTlmo5qpro2Zaeq0dMc10090 rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090 intact-crc:397DBFD9EBFF6608|rigid:RJzX2Z97Nm0qWuq3N2F0oCB7IXo false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P17426 uniprotkb:Q8VD37 intact:EBI-775189|ensembl:ENSMUSP00000082519|ensembl:ENSMUSP00000127842 intact:EBI-776269|uniprotkb:A7BFW0|uniprotkb:Q3UFU3|uniprotkb:Q3UGA0|uniprotkb:Q8BXX4|uniprotkb:Q8C034|uniprotkb:Q9CXT2|ensembl:ENSMUSP00000079553 psi-mi:ap2a1_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Ap2a1(gene name)|psi-mi:Ap2a1(display_short)|uniprotkb:Adtaa(gene name synonym)|uniprotkb:Clapa1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym) psi-mi:sgip1_mouse(display_long)|uniprotkb:Endophilin-3-interacting protein(gene name synonym)|uniprotkb:Sgip1(gene name)|psi-mi:Sgip1(display_short) psi-mi:"MI:0663"(confocal microscopy) Uezu et al. (2007) pubmed:17626015 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6116308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070732.1|refseq:NP_031484.1|ensembl:ENSMUSG00000060279(gene)|ensembl:ENSMUST00000085399(transcript)|ensembl:ENSMUST00000166972(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0032433"(filopodium tip)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17426|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038 refseq:NP_659155.1|refseq:NP_001272788.1|refseq:NP_001272789.1|refseq:NP_001272791.1|refseq:XP_006503491.1|refseq:XP_017175890.1|ensembl:ENSMUSG00000028524(gene)|ensembl:ENSMUST00000080728(transcript)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098793"(presynapse)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR018808|interpro:IPR028565|interpro:IPR036168|interpro:IPR037984|mint:Q8VD37|reactome:R-MMU-8856825|reactome:R-MMU-8856828 - - - figure legend:fig 5|curation depth:mimix curation taxid:10090(mouse-n1e-115)|taxid:10090(Mus musculus neuroblastoma cells) - 2012/05/03 2014/10/16 rogid:Dd6Q+Et/LTlmo5qpro2Zaeq0dMc10090 rogid:5TUgNAM4+5qY6EfbMvqhjc/i3/U10090 intact-crc:397DBFD9EBFF6608|rigid:RJzX2Z97Nm0qWuq3N2F0oCB7IXo false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)