#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P69776	uniprotkb:P02929	intact:EBI-909750|ensemblbacteria:AAC74747|ensemblbacteria:BAA16044|uniprotkb:P02937|uniprotkb:Q53272	intact:EBI-6399993|ensemblbacteria:AAC74334|ensemblbacteria:BAA14784|uniprotkb:P76831|uniprotkb:P94719|uniprotkb:P94722|uniprotkb:P94726|uniprotkb:P94728|uniprotkb:P94732|uniprotkb:P94736|uniprotkb:P94739|uniprotkb:P97239	psi-mi:lpp_ecoli(display_long)|uniprotkb:lpp(gene name)|psi-mi:lpp(display_short)|uniprotkb:mlpA(gene name synonym)|uniprotkb:mulI(gene name synonym)|uniprotkb:b1677(locus name)|uniprotkb:JW1667(locus name)|uniprotkb:Braun lipoprotein(gene name synonym)|uniprotkb:Murein-lipoprotein(gene name synonym)	psi-mi:tonb_ecoli(display_long)|uniprotkb:tonB(gene name)|psi-mi:tonB(display_short)|uniprotkb:exbA(gene name synonym)|uniprotkb:JW5195(locus name)|uniprotkb:b1252(locus name)	psi-mi:"MI:0030"(cross-linking study)	Vakharia-Rao et al. (2007)	pubmed:17483231|imex:IM-18502	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6400007|mpidb:MPIDB-INT-2081|imex:IM-18502-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1KFN|rcsb pdb:1MLP|rcsb pdb:1T8Z|rcsb pdb:2GUS|rcsb pdb:2GUV|ensemblbacteria:AAC74747(transcript)|ensemblbacteria:b1677(gene)|ensemblbacteria:BAA16044(gene)|ensemblbacteria:BAA16044(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0008289"(lipid binding)|go:"GO:0009279"(cell outer membrane)|go:"GO:0016020"(membrane)|go:"GO:0030258"(lipid modification)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031230"(intrinsic component of cell outer membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043580"(periplasmic space organization)|go:"GO:0045203"(integral component of cell outer membrane)|interpro:IPR006817(LPP motif)|interpro:IPR016367(Murein-lipoprotein)|rcsb pdb:1EQ7|rcsb pdb:1JCC|rcsb pdb:1JCD|rcsb pdb:1KFM|refseq:NP_416192.1|refseq:WP_000648420.1|dip:DIP-35674N	refseq:WP_001360141.1|ensemblbacteria:AAC74334(transcript)|ensemblbacteria:b1252(gene)|ensemblbacteria:BAA14784(gene)|ensemblbacteria:BAA14784(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015891"(siderophore transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042914"(colicin transport)|go:"GO:0071575"(integral component of external side of plasma membrane)|go:"GO:0098002"(receptor-mediated bacteriophage irreversible attachment to host cell)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003538(Gram-negative bacterial tonB protein)|interpro:IPR006260(TonB, C-terminal)|interpro:IPR037682|rcsb pdb:1IHR|rcsb pdb:1QXX|rcsb pdb:1U07|rcsb pdb:1XX3|rcsb pdb:2GRX|rcsb pdb:2GSK|refseq:NP_415768.1|dip:DIP-48111N	-	-	-	figure legend:figure 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/11/30	2014/10/16	rogid:MSU6I8nZGpwfkax0HPNB+PLtHqw83333	rogid:ia5lbqqvP+O4DJyZcLSRdxZV/tE83333	intact-crc:8D5AAEA6C7652A6F|rigid:J/Up53sofeoLWQp/AW0gtGDUrik	false	-	necessary binding region:159-161	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0ABU7	uniprotkb:P02929	intact:EBI-6399986|ensemblbacteria:AAC76042|ensemblbacteria:BAE77064|uniprotkb:Q2M9J2|uniprotkb:P18783	intact:EBI-6399993|ensemblbacteria:AAC74334|ensemblbacteria:BAA14784|uniprotkb:P76831|uniprotkb:P94719|uniprotkb:P94722|uniprotkb:P94726|uniprotkb:P94728|uniprotkb:P94732|uniprotkb:P94736|uniprotkb:P94739|uniprotkb:P97239	psi-mi:exbb_ecoli(display_long)|uniprotkb:JW2974(locus name)|uniprotkb:b3006(locus name)|uniprotkb:exbB(gene name)|psi-mi:exbB(display_short)	psi-mi:tonb_ecoli(display_long)|uniprotkb:tonB(gene name)|psi-mi:tonB(display_short)|uniprotkb:exbA(gene name synonym)|uniprotkb:JW5195(locus name)|uniprotkb:b1252(locus name)	psi-mi:"MI:0030"(cross-linking study)	Vakharia-Rao et al. (2007)	pubmed:17483231|imex:IM-18502	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6399982|mpidb:MPIDB-INT-2082|imex:IM-18502-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000527844.1|ensemblbacteria:AAC76042(transcript)|ensemblbacteria:b3006(gene)|ensemblbacteria:BAE77064(gene)|ensemblbacteria:BAE77064(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0017038"(protein import)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043213"(bacteriocin transport)|go:"GO:0050821"(protein stabilization)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR002898(MotA/TolQ/ExbB proton channel)|interpro:IPR014164(TonB-system energizer ExbB type-1)|rcsb pdb:5SV0|rcsb pdb:5SV1|rcsb pdb:5ZFP|rcsb pdb:5ZFU|rcsb pdb:5ZFV|rcsb pdb:6TYI|refseq:NP_417479.1|dip:DIP-47841N	refseq:WP_001360141.1|ensemblbacteria:AAC74334(transcript)|ensemblbacteria:b1252(gene)|ensemblbacteria:BAA14784(gene)|ensemblbacteria:BAA14784(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015891"(siderophore transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042914"(colicin transport)|go:"GO:0071575"(integral component of external side of plasma membrane)|go:"GO:0098002"(receptor-mediated bacteriophage irreversible attachment to host cell)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003538(Gram-negative bacterial tonB protein)|interpro:IPR006260(TonB, C-terminal)|interpro:IPR037682|rcsb pdb:1IHR|rcsb pdb:1QXX|rcsb pdb:1U07|rcsb pdb:1XX3|rcsb pdb:2GRX|rcsb pdb:2GSK|refseq:NP_415768.1|dip:DIP-48111N	-	-	-	figure legend:figure 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/11/30	2014/10/16	rogid:GzwmzYgXdmqOnn7zckGnEBCzDf883333	rogid:ia5lbqqvP+O4DJyZcLSRdxZV/tE83333	intact-crc:8CC6BDD8FF65DC50|rigid:NLMbIGEBulWdEd9I2LTkhugD2D8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02929	uniprotkb:P02929	intact:EBI-6399993|ensemblbacteria:AAC74334|ensemblbacteria:BAA14784|uniprotkb:P76831|uniprotkb:P94719|uniprotkb:P94722|uniprotkb:P94726|uniprotkb:P94728|uniprotkb:P94732|uniprotkb:P94736|uniprotkb:P94739|uniprotkb:P97239	intact:EBI-6399993|ensemblbacteria:AAC74334|ensemblbacteria:BAA14784|uniprotkb:P76831|uniprotkb:P94719|uniprotkb:P94722|uniprotkb:P94726|uniprotkb:P94728|uniprotkb:P94732|uniprotkb:P94736|uniprotkb:P94739|uniprotkb:P97239	psi-mi:tonb_ecoli(display_long)|uniprotkb:tonB(gene name)|psi-mi:tonB(display_short)|uniprotkb:exbA(gene name synonym)|uniprotkb:JW5195(locus name)|uniprotkb:b1252(locus name)	psi-mi:tonb_ecoli(display_long)|uniprotkb:tonB(gene name)|psi-mi:tonB(display_short)|uniprotkb:exbA(gene name synonym)|uniprotkb:JW5195(locus name)|uniprotkb:b1252(locus name)	psi-mi:"MI:0030"(cross-linking study)	Vakharia-Rao et al. (2007)	pubmed:17483231|imex:IM-18502	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6400048|mpidb:MPIDB-INT-2083|imex:IM-18502-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001360141.1|ensemblbacteria:AAC74334(transcript)|ensemblbacteria:b1252(gene)|ensemblbacteria:BAA14784(gene)|ensemblbacteria:BAA14784(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015891"(siderophore transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042914"(colicin transport)|go:"GO:0071575"(integral component of external side of plasma membrane)|go:"GO:0098002"(receptor-mediated bacteriophage irreversible attachment to host cell)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003538(Gram-negative bacterial tonB protein)|interpro:IPR006260(TonB, C-terminal)|interpro:IPR037682|rcsb pdb:1IHR|rcsb pdb:1QXX|rcsb pdb:1U07|rcsb pdb:1XX3|rcsb pdb:2GRX|rcsb pdb:2GSK|refseq:NP_415768.1|dip:DIP-48111N	refseq:WP_001360141.1|ensemblbacteria:AAC74334(transcript)|ensemblbacteria:b1252(gene)|ensemblbacteria:BAA14784(gene)|ensemblbacteria:BAA14784(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015891"(siderophore transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042914"(colicin transport)|go:"GO:0071575"(integral component of external side of plasma membrane)|go:"GO:0098002"(receptor-mediated bacteriophage irreversible attachment to host cell)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003538(Gram-negative bacterial tonB protein)|interpro:IPR006260(TonB, C-terminal)|interpro:IPR037682|rcsb pdb:1IHR|rcsb pdb:1QXX|rcsb pdb:1U07|rcsb pdb:1XX3|rcsb pdb:2GRX|rcsb pdb:2GSK|refseq:NP_415768.1|dip:DIP-48111N	-	-	-	figure legend:figure 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/11/30	2014/10/16	rogid:ia5lbqqvP+O4DJyZcLSRdxZV/tE83333	rogid:ia5lbqqvP+O4DJyZcLSRdxZV/tE83333	intact-crc:26125AC6D951DB97|rigid:ggQ7Hbg7USed54oADK8EA7XPvUI	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02929	uniprotkb:P05825	intact:EBI-6399993|ensemblbacteria:AAC74334|ensemblbacteria:BAA14784|uniprotkb:P76831|uniprotkb:P94719|uniprotkb:P94722|uniprotkb:P94726|uniprotkb:P94728|uniprotkb:P94732|uniprotkb:P94736|uniprotkb:P94739|uniprotkb:P97239	intact:EBI-6400027|ensemblbacteria:AAC73685|ensemblbacteria:BAA35225|uniprotkb:P75722|uniprotkb:P76821|uniprotkb:P77093	psi-mi:tonb_ecoli(display_long)|uniprotkb:tonB(gene name)|psi-mi:tonB(display_short)|uniprotkb:exbA(gene name synonym)|uniprotkb:JW5195(locus name)|uniprotkb:b1252(locus name)	psi-mi:fepa_ecoli(display_long)|uniprotkb:Enterobactin outer-membrane receptor(gene name synonym)|uniprotkb:fep(gene name synonym)|uniprotkb:feuB(gene name synonym)|uniprotkb:JW5086(locus name)|uniprotkb:b0584(locus name)|uniprotkb:fepA(gene name)|psi-mi:fepA(display_short)	psi-mi:"MI:0030"(cross-linking study)	Vakharia-Rao et al. (2007)	pubmed:17483231|imex:IM-18502	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6400023|mpidb:MPIDB-INT-2080|imex:IM-18502-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001360141.1|ensemblbacteria:AAC74334(transcript)|ensemblbacteria:b1252(gene)|ensemblbacteria:BAA14784(gene)|ensemblbacteria:BAA14784(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015891"(siderophore transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042914"(colicin transport)|go:"GO:0071575"(integral component of external side of plasma membrane)|go:"GO:0098002"(receptor-mediated bacteriophage irreversible attachment to host cell)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003538(Gram-negative bacterial tonB protein)|interpro:IPR006260(TonB, C-terminal)|interpro:IPR037682|rcsb pdb:1IHR|rcsb pdb:1QXX|rcsb pdb:1U07|rcsb pdb:1XX3|rcsb pdb:2GRX|rcsb pdb:2GSK|refseq:NP_415768.1|dip:DIP-48111N	refseq:WP_001034943.1|ensemblbacteria:AAC73685(transcript)|ensemblbacteria:BAA35225(gene)|ensemblbacteria:BAA35225(transcript)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015344"(siderophore uptake transmembrane transporter activity)|go:"GO:0015620"(ferric-enterobactin transmembrane transporter activity)|go:"GO:0015685"(ferric-enterobactin import into cell)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022834"(ligand-gated channel activity)|go:"GO:0030313"(cell envelope)|go:"GO:0031230"(intrinsic component of cell outer membrane)|go:"GO:0033214"(siderophore-dependent iron import into cell)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042912"(colicin transmembrane transporter activity)|go:"GO:0042914"(colicin transport)|go:"GO:0042930"(enterobactin transport)|go:"GO:0042931"(enterobactin transmembrane transporter activity)|go:"GO:0044718"(siderophore transmembrane transport)|go:"GO:0045203"(integral component of cell outer membrane)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|rcsb pdb:1FEP|ensemblbacteria:b0584(gene)|refseq:NP_415116.1|dip:DIP-9592N	-	-	-	figure legend:figure 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2012/11/30	2014/10/16	rogid:ia5lbqqvP+O4DJyZcLSRdxZV/tE83333	rogid:cL3M2iMURVuk6kKPV54taVebqYw83333	intact-crc:BD92AB6C7ED82F4C|rigid:nDhBMPAQOsrM09gQwHsUWJSvOo0	false	necessary binding region:159-161	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)