#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NYF0	uniprotkb:O14641	intact:EBI-3951744|uniprotkb:Q86TY0|ensembl:ENSP00000337439|uniprotkb:A8MYJ2	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dact1_human(display_long)|uniprotkb:DACT1(gene name)|psi-mi:DACT1(display_short)|uniprotkb:DPR1(gene name synonym)|uniprotkb:HNG3(gene name synonym)|uniprotkb:Hepatocellular carcinoma novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhang et al. (2006)	pubmed:16446366|imex:IM-17550	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6253930|imex:IM-17550-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165617(gene)|ensembl:ENST00000335867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-HSA-4641258|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|refseq:NP_057735.2|refseq:NP_001072988.1|refseq:XP_006720230.1	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/07/25	2014/10/16	rogid:4LFgplvhFtCWUI/6Pux6Z23NNVY9606	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:858A51AA92128040|rigid:2MYVFEPZsaLqQo2L5SXuZvcHoLQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NYF0	uniprotkb:O14641	intact:EBI-3951744|uniprotkb:Q86TY0|ensembl:ENSP00000337439|uniprotkb:A8MYJ2	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dact1_human(display_long)|uniprotkb:DACT1(gene name)|psi-mi:DACT1(display_short)|uniprotkb:DPR1(gene name synonym)|uniprotkb:HNG3(gene name synonym)|uniprotkb:Hepatocellular carcinoma novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0428"(imaging technique)	Zhang et al. (2006)	pubmed:16446366|imex:IM-17550	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6253993|imex:IM-17550-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165617(gene)|ensembl:ENST00000335867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-HSA-4641258|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|refseq:NP_057735.2|refseq:NP_001072988.1|refseq:XP_006720230.1	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	go:"GO:0005737"(cytoplasm)	-	-	figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/07/25	2014/10/16	rogid:4LFgplvhFtCWUI/6Pux6Z23NNVY9606	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:F0FD3F8F122DDABC|rigid:2MYVFEPZsaLqQo2L5SXuZvcHoLQ	false	sufficient binding region:1-619|sufficient binding region:611-836|myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9NYF0	uniprotkb:O14641	intact:EBI-3951744|uniprotkb:Q86TY0|ensembl:ENSP00000337439|uniprotkb:A8MYJ2	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dact1_human(display_long)|uniprotkb:DACT1(gene name)|psi-mi:DACT1(display_short)|uniprotkb:DPR1(gene name synonym)|uniprotkb:HNG3(gene name synonym)|uniprotkb:Hepatocellular carcinoma novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0428"(imaging technique)	Zhang et al. (2006)	pubmed:16446366|imex:IM-17550	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6253943|imex:IM-17550-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165617(gene)|ensembl:ENST00000335867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-HSA-4641258|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|refseq:NP_057735.2|refseq:NP_001072988.1|refseq:XP_006720230.1	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	go:"GO:0005737"(cytoplasm)	-	-	figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/07/25	2014/10/16	rogid:4LFgplvhFtCWUI/6Pux6Z23NNVY9606	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:F0FD3A2F122DDABC|rigid:2MYVFEPZsaLqQo2L5SXuZvcHoLQ	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9NYF0	uniprotkb:O14641	intact:EBI-3951744|uniprotkb:Q86TY0|ensembl:ENSP00000337439|uniprotkb:A8MYJ2	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dact1_human(display_long)|uniprotkb:DACT1(gene name)|psi-mi:DACT1(display_short)|uniprotkb:DPR1(gene name synonym)|uniprotkb:HNG3(gene name synonym)|uniprotkb:Hepatocellular carcinoma novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zhang et al. (2006)	pubmed:16446366|imex:IM-17550	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6253957|imex:IM-17550-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165617(gene)|ensembl:ENST00000335867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-HSA-4641258|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|refseq:NP_057735.2|refseq:NP_001072988.1|refseq:XP_006720230.1	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	figure legend:3A and 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/25	2014/10/16	rogid:4LFgplvhFtCWUI/6Pux6Z23NNVY9606	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:9BB0B96B26DF137E|rigid:2MYVFEPZsaLqQo2L5SXuZvcHoLQ	false	myc tag:?-?|sufficient binding region:1-619|sufficient binding region:611-836	necessary binding region:365-667|flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NYF0	uniprotkb:O14641	intact:EBI-3951744|uniprotkb:Q86TY0|ensembl:ENSP00000337439|uniprotkb:A8MYJ2	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dact1_human(display_long)|uniprotkb:DACT1(gene name)|psi-mi:DACT1(display_short)|uniprotkb:DPR1(gene name synonym)|uniprotkb:HNG3(gene name synonym)|uniprotkb:Hepatocellular carcinoma novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zhang et al. (2006)	pubmed:16446366|imex:IM-17550	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6253967|imex:IM-17550-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165617(gene)|ensembl:ENST00000335867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-HSA-4641258|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|refseq:NP_057735.2|refseq:NP_001072988.1|refseq:XP_006720230.1	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/25	2014/10/16	rogid:4LFgplvhFtCWUI/6Pux6Z23NNVY9606	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:16245314933757F3|rigid:2MYVFEPZsaLqQo2L5SXuZvcHoLQ	false	ha tag:?-?	flag tag:?-?|sufficient binding region:429-593	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8R4A3	uniprotkb:O14641	intact:EBI-3870250|uniprotkb:Q80VG9|uniprotkb:Q8BP49|uniprotkb:Q9JK89|ensembl:ENSMUSP00000058943	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dact1_mouse(display_long)|uniprotkb:Dact1(gene name)|psi-mi:Dact1(display_short)|uniprotkb:Thyex3(gene name synonym)|uniprotkb:MDpr1(gene name synonym)|uniprotkb:Thymus-expressed novel gene 3 protein(gene name synonym)|uniprotkb:Dapper antagonist of catenin 1(gene name synonym)|uniprotkb:Frodo homolog(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zhang et al. (2006)	pubmed:16446366|imex:IM-17550	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6253983|imex:IM-17550-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067507.2|ensembl:ENSMUSG00000044548(gene)|ensembl:ENSMUST00000061273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904864"(negative regulation of beta-catenin-TCF complex assembly)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR024843|interpro:IPR024848|reactome:R-MMU-4641258	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/25	2014/10/16	rogid:4H0/7x/8V7exiwAQsQo6EnanUN410090	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:0D28B2891FE41F7A|rigid:nasJOQUy/AtPFSKTVNAkAiLB/1Y	false	myc tag:?-?|binding-associated region:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)