#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q811U3 uniprotkb:Q9JIR4 intact:EBI-3507502|uniprotkb:Q8CIY9 intact:EBI-3507436|uniprotkb:O35168 psi-mi:rb6i2_rat(display_long)|uniprotkb:Erc1(gene name)|psi-mi:Erc1(display_short)|uniprotkb:Cast2(gene name synonym)|uniprotkb:Elks(gene name synonym)|uniprotkb:Rab6ip2(gene name synonym)|uniprotkb:CAZ-associated structural protein 2(gene name synonym)|uniprotkb:Rab6-interacting protein 2(gene name synonym) psi-mi:rims1_rat(display_long)|uniprotkb:Rims1(gene name)|psi-mi:Rims1(display_short)|uniprotkb:Rim1(gene name synonym)|uniprotkb:Rab-3-interacting molecule 1(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Lu et al. (2005) pubmed:16095618 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-6466580|pdbe:1ZUB - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628733|refseq:NP_740769.2|interpro:IPR019323|rcsb pdb:1ZUB|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045202"(synapse)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels) rgd:620000|refseq:NP_439894.1|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060478"(acrosomal vesicle exocytosis)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035892|interpro:IPR036034|interpro:IPR039032|interpro:IPR041282|rcsb pdb:1ZUB|rcsb pdb:2Q3X|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-888590|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010808"(positive regulation of synaptic vesicle priming)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031632"(positive regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0060077"(inhibitory synapse)|mint:Q9JIR4|dip:DIP-41432N - - - figure legend:Fig 1|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/20 2014/10/16 rogid:MmEtwA0YnPzpPTRO8H6JpP688Hs10116 rogid:Qk1J57peZ9ZCLtiLg1v5R4LAlF410116 intact-crc:6384AE49D7AEA55E|rigid:4GDvSt1kdeWo4YJKegKewfDAYXo false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q811U3 uniprotkb:Q9JIR4 intact:EBI-3507502|uniprotkb:Q8CIY9 intact:EBI-3507436|uniprotkb:O35168 psi-mi:rb6i2_rat(display_long)|uniprotkb:Erc1(gene name)|psi-mi:Erc1(display_short)|uniprotkb:Cast2(gene name synonym)|uniprotkb:Elks(gene name synonym)|uniprotkb:Rab6ip2(gene name synonym)|uniprotkb:CAZ-associated structural protein 2(gene name synonym)|uniprotkb:Rab6-interacting protein 2(gene name synonym) psi-mi:rims1_rat(display_long)|uniprotkb:Rims1(gene name)|psi-mi:Rims1(display_short)|uniprotkb:Rim1(gene name synonym)|uniprotkb:Rab-3-interacting molecule 1(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Lu et al. (2005) pubmed:16095618 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-6466641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628733|refseq:NP_740769.2|interpro:IPR019323|rcsb pdb:1ZUB|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045202"(synapse)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels) rgd:620000|refseq:NP_439894.1|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060478"(acrosomal vesicle exocytosis)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035892|interpro:IPR036034|interpro:IPR039032|interpro:IPR041282|rcsb pdb:1ZUB|rcsb pdb:2Q3X|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-888590|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010808"(positive regulation of synaptic vesicle priming)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031632"(positive regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0060077"(inhibitory synapse)|mint:Q9JIR4|dip:DIP-41432N - - - figure legend:Fig 2.|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/20 2014/10/16 rogid:MmEtwA0YnPzpPTRO8H6JpP688Hs10116 rogid:Qk1J57peZ9ZCLtiLg1v5R4LAlF410116 intact-crc:8B93342A296FF580|rigid:4GDvSt1kdeWo4YJKegKewfDAYXo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)