#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8I100	uniprotkb:Q19088	intact:EBI-2655296|ensemblmetazoa:Y39A1A.5.1	intact:EBI-318878|ensemblmetazoa:F01F1.4.1|ensemblmetazoa:F01F1.4.2	psi-mi:q8i100_caeel(display_long)|uniprotkb:rabx-5(gene name)|psi-mi:rabx-5(display_short)|uniprotkb:CELE_Y39A1A.5(orf name)|uniprotkb:Y39A1A.5(orf name)	psi-mi:q19088_caeel(display_long)|uniprotkb:rabn-5(gene name)|psi-mi:rabn-5(display_short)|uniprotkb:F01F1.4(orf name)|uniprotkb:CELE_F01F1.4(orf name)	psi-mi:"MI:0018"(two hybrid)	Sato et al. (2005)	pubmed:15895077|imex:IM-16882	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5323223|imex:IM-16882-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR002653(Zinc finger, A20-type)|refseq:NP_499337.3|ensemblmetazoa:WBGene00012644(gene)|ensemblmetazoa:Y39A1A.5.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005769"(early endosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018996"(molting cycle, collagen and cuticulin-based cuticle)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0043547"(positive regulation of GTPase activity)|wormbase:Y39A1A.5a|interpro:IPR037191|interpro:IPR041545	refseq:NP_498266.1|wormbase:F01F1.4|ensemblmetazoa:F01F1.4.1(transcript)|ensemblmetazoa:F01F1.4.2(transcript)|ensemblmetazoa:WBGene00017161(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006897"(endocytosis)|go:"GO:0018996"(molting cycle, collagen and cuticulin-based cuticle)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR003914(Rabaptin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR017455(Zinc finger, FYVE-related)|dip:DIP-26972N	-	-	-	figure legend:Supplementary Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/01/03	2014/10/16	rogid:ezj5PejKoVjtQDy3FxdHf/katH06239	rogid:rDx7/0HyFYJBplCfN/XYyNIxtXs6239	intact-crc:8E679C5BBA25E7D9|rigid:lba86v6YRlNMeVE8qc516FVXlqs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9GYH7	uniprotkb:P91857	intact:EBI-320814|uniprotkb:Q8MNR6|uniprotkb:Q4VQC9|ensemblmetazoa:F49E7.1a.1	intact:EBI-2655330|ensemblmetazoa:F26H9.6.1	psi-mi:rme6_caeel(display_long)|uniprotkb:rme-6(gene name)|psi-mi:rme-6(display_short)|uniprotkb:F49E7.1(orf name)	psi-mi:p91857_caeel(display_long)|uniprotkb:rab-5(gene name)|psi-mi:rab-5(display_short)|uniprotkb:CELE_F26H9.6(orf name)|uniprotkb:F26H9.6(orf name)	psi-mi:"MI:0018"(two hybrid)	Sato et al. (2005)	pubmed:15895077|imex:IM-16882	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5323176|imex:IM-16882-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_508208.2|wormbase:F49E7.1a|wormbase:F49E7.1b|ensemblmetazoa:F49E7.1a.1(transcript)|ensemblmetazoa:WBGene00004377(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0018996"(molting cycle, collagen and cuticulin-based cuticle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0051223"(regulation of protein transport)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR037191|refseq:NP_001294826.1|reactome:R-CEL-8856828|reactome:R-CEL-8876198|dip:DIP-25631N	reactome:R-CEL-8854214|refseq:NP_492481.1|wormbase:F26H9.6|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|reactome:R-CEL-8856828|reactome:R-CEL-8876198|ensemblmetazoa:F26H9.6.1(transcript)|ensemblmetazoa:WBGene00004268(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009306"(protein secretion)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0012505"(endomembrane system)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:1990075"(periciliary membrane compartment)|reactome:R-CEL-8873719|interpro:IPR027417|reactome:R-CEL-983231|reactome:R-CEL-432722|reactome:R-CEL-6798695	-	-	-	figure legend:Fig 2|comment:"RME-6 specifically interacted with RAB-5(S33N)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/01/03	2014/10/16	rogid:k3oGrJUWh+RqwyXoWrq00tnnwjg6239	rogid:AjNtZMRSZi1JHLACug8RdfJV/U46239	intact-crc:A454FA7F81A4C247|rigid:fqt0YopvWDi/n3tpWnnYQkh4/LA	false	-	mutation:33-33	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8I100	uniprotkb:P91857	intact:EBI-2655296|ensemblmetazoa:Y39A1A.5.1	intact:EBI-2655330|ensemblmetazoa:F26H9.6.1	psi-mi:q8i100_caeel(display_long)|uniprotkb:rabx-5(gene name)|psi-mi:rabx-5(display_short)|uniprotkb:CELE_Y39A1A.5(orf name)|uniprotkb:Y39A1A.5(orf name)	psi-mi:p91857_caeel(display_long)|uniprotkb:rab-5(gene name)|psi-mi:rab-5(display_short)|uniprotkb:CELE_F26H9.6(orf name)|uniprotkb:F26H9.6(orf name)	psi-mi:"MI:0018"(two hybrid)	Sato et al. (2005)	pubmed:15895077|imex:IM-16882	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5323216|imex:IM-16882-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR002653(Zinc finger, A20-type)|refseq:NP_499337.3|ensemblmetazoa:WBGene00012644(gene)|ensemblmetazoa:Y39A1A.5.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005769"(early endosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018996"(molting cycle, collagen and cuticulin-based cuticle)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0043547"(positive regulation of GTPase activity)|wormbase:Y39A1A.5a|interpro:IPR037191|interpro:IPR041545	reactome:R-CEL-8854214|refseq:NP_492481.1|wormbase:F26H9.6|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|reactome:R-CEL-8856828|reactome:R-CEL-8876198|ensemblmetazoa:F26H9.6.1(transcript)|ensemblmetazoa:WBGene00004268(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009306"(protein secretion)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0012505"(endomembrane system)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:1990075"(periciliary membrane compartment)|reactome:R-CEL-8873719|interpro:IPR027417|reactome:R-CEL-983231|reactome:R-CEL-432722|reactome:R-CEL-6798695	-	-	-	figure legend:Supplementary Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/01/03	2014/10/16	rogid:ezj5PejKoVjtQDy3FxdHf/katH06239	rogid:AjNtZMRSZi1JHLACug8RdfJV/U46239	intact-crc:14EE788962F661D8|rigid:m/wMm2MQcswic0wIDhHILMuno88	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P91857	uniprotkb:Q9GYH7	intact:EBI-2655330|ensemblmetazoa:F26H9.6.1	intact:EBI-320814|uniprotkb:Q8MNR6|uniprotkb:Q4VQC9|ensemblmetazoa:F49E7.1a.1	psi-mi:p91857_caeel(display_long)|uniprotkb:rab-5(gene name)|psi-mi:rab-5(display_short)|uniprotkb:CELE_F26H9.6(orf name)|uniprotkb:F26H9.6(orf name)	psi-mi:rme6_caeel(display_long)|uniprotkb:rme-6(gene name)|psi-mi:rme-6(display_short)|uniprotkb:F49E7.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sato et al. (2005)	pubmed:15895077|imex:IM-16882	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5323291|imex:IM-16882-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-CEL-8854214|refseq:NP_492481.1|wormbase:F26H9.6|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|reactome:R-CEL-8856828|reactome:R-CEL-8876198|ensemblmetazoa:F26H9.6.1(transcript)|ensemblmetazoa:WBGene00004268(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009306"(protein secretion)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0012505"(endomembrane system)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:1990075"(periciliary membrane compartment)|reactome:R-CEL-8873719|interpro:IPR027417|reactome:R-CEL-983231|reactome:R-CEL-432722|reactome:R-CEL-6798695	refseq:NP_508208.2|wormbase:F49E7.1a|wormbase:F49E7.1b|ensemblmetazoa:F49E7.1a.1(transcript)|ensemblmetazoa:WBGene00004377(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0018996"(molting cycle, collagen and cuticulin-based cuticle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0051223"(regulation of protein transport)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR037191|refseq:NP_001294826.1|reactome:R-CEL-8856828|reactome:R-CEL-8876198|dip:DIP-25631N	-	-	-	figure legend:Fig 2|comment:"RME-6 specifically interacted with RAB-5(S33N)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2012/01/03	2014/10/16	rogid:AjNtZMRSZi1JHLACug8RdfJV/U46239	rogid:k3oGrJUWh+RqwyXoWrq00tnnwjg6239	intact-crc:084F3725860CCCB5|rigid:fqt0YopvWDi/n3tpWnnYQkh4/LA	false	mutation:33-33|ha tag:n-n	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9GYH7	uniprotkb:Q22601	intact:EBI-320814|uniprotkb:Q8MNR6|uniprotkb:Q4VQC9|ensemblmetazoa:F49E7.1a.1	intact:EBI-5323248|ensemblmetazoa:T20B5.1.1|ensemblmetazoa:T20B5.1.2|ensemblmetazoa:T20B5.1.3	psi-mi:rme6_caeel(display_long)|uniprotkb:rme-6(gene name)|psi-mi:rme-6(display_short)|uniprotkb:F49E7.1(orf name)	psi-mi:q22601_caeel(display_long)|uniprotkb:T20B5.1(orf name)|uniprotkb:apa-2(gene name)|psi-mi:apa-2(display_short)|uniprotkb:CELE_T20B5.1(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Sato et al. (2005)	pubmed:15895077|imex:IM-16882	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5323343|imex:IM-16882-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_508208.2|wormbase:F49E7.1a|wormbase:F49E7.1b|ensemblmetazoa:F49E7.1a.1(transcript)|ensemblmetazoa:WBGene00004377(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0018996"(molting cycle, collagen and cuticulin-based cuticle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0051223"(regulation of protein transport)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR037191|refseq:NP_001294826.1|reactome:R-CEL-8856828|reactome:R-CEL-8876198|dip:DIP-25631N	interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|mint:Q22601|refseq:NP_509572.1|wormbase:T20B5.1|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|go:"GO:0006886"(intracellular protein transport)|ensemblmetazoa:T20B5.1.1(transcript)|ensemblmetazoa:T20B5.1.2(transcript)|ensemblmetazoa:T20B5.1.3(transcript)|ensemblmetazoa:WBGene00000161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0045202"(synapse)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-6798695|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|go:"GO:0008022"(protein C-terminus binding)	-	-	-	figure legend:Fig 7b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2012/01/03	2014/10/16	rogid:k3oGrJUWh+RqwyXoWrq00tnnwjg6239	rogid:h1D5aAR/42LZEGamNt9ibHcovUg6239	intact-crc:142DC6856B1D470A|rigid:hbJ9rEYmyg/1DYlVW2GFuDzxBMg	false	green fluorescent protein tag:n-n	red fluorescent protein tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q22601	uniprotkb:Q9GYH7	intact:EBI-5323248|ensemblmetazoa:T20B5.1.1|ensemblmetazoa:T20B5.1.2|ensemblmetazoa:T20B5.1.3	intact:EBI-320814|uniprotkb:Q8MNR6|uniprotkb:Q4VQC9|ensemblmetazoa:F49E7.1a.1	psi-mi:q22601_caeel(display_long)|uniprotkb:T20B5.1(orf name)|uniprotkb:apa-2(gene name)|psi-mi:apa-2(display_short)|uniprotkb:CELE_T20B5.1(orf name)	psi-mi:rme6_caeel(display_long)|uniprotkb:rme-6(gene name)|psi-mi:rme-6(display_short)|uniprotkb:F49E7.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sato et al. (2005)	pubmed:15895077|imex:IM-16882	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5323237|imex:IM-16882-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|mint:Q22601|refseq:NP_509572.1|wormbase:T20B5.1|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|go:"GO:0006886"(intracellular protein transport)|ensemblmetazoa:T20B5.1.1(transcript)|ensemblmetazoa:T20B5.1.2(transcript)|ensemblmetazoa:T20B5.1.3(transcript)|ensemblmetazoa:WBGene00000161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0045202"(synapse)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-6798695|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|go:"GO:0008022"(protein C-terminus binding)	refseq:NP_508208.2|wormbase:F49E7.1a|wormbase:F49E7.1b|ensemblmetazoa:F49E7.1a.1(transcript)|ensemblmetazoa:WBGene00004377(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0018996"(molting cycle, collagen and cuticulin-based cuticle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0051223"(regulation of protein transport)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR037191|refseq:NP_001294826.1|reactome:R-CEL-8856828|reactome:R-CEL-8876198|dip:DIP-25631N	-	-	-	figure legend:Fig 8e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2012/01/03	2014/10/16	rogid:h1D5aAR/42LZEGamNt9ibHcovUg6239	rogid:k3oGrJUWh+RqwyXoWrq00tnnwjg6239	intact-crc:830FC29AA9874DBF|rigid:hbJ9rEYmyg/1DYlVW2GFuDzxBMg	false	-	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q22601	uniprotkb:Q9GYH7	intact:EBI-5323248|ensemblmetazoa:T20B5.1.1|ensemblmetazoa:T20B5.1.2|ensemblmetazoa:T20B5.1.3	intact:EBI-320814|uniprotkb:Q8MNR6|uniprotkb:Q4VQC9|ensemblmetazoa:F49E7.1a.1	psi-mi:q22601_caeel(display_long)|uniprotkb:T20B5.1(orf name)|uniprotkb:apa-2(gene name)|psi-mi:apa-2(display_short)|uniprotkb:CELE_T20B5.1(orf name)	psi-mi:rme6_caeel(display_long)|uniprotkb:rme-6(gene name)|psi-mi:rme-6(display_short)|uniprotkb:F49E7.1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sato et al. (2005)	pubmed:15895077|imex:IM-16882	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5323323|imex:IM-16882-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|mint:Q22601|refseq:NP_509572.1|wormbase:T20B5.1|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|go:"GO:0006886"(intracellular protein transport)|ensemblmetazoa:T20B5.1.1(transcript)|ensemblmetazoa:T20B5.1.2(transcript)|ensemblmetazoa:T20B5.1.3(transcript)|ensemblmetazoa:WBGene00000161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0045202"(synapse)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-6798695|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|go:"GO:0008022"(protein C-terminus binding)	refseq:NP_508208.2|wormbase:F49E7.1a|wormbase:F49E7.1b|ensemblmetazoa:F49E7.1a.1(transcript)|ensemblmetazoa:WBGene00004377(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0018996"(molting cycle, collagen and cuticulin-based cuticle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0051223"(regulation of protein transport)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR037191|refseq:NP_001294826.1|reactome:R-CEL-8856828|reactome:R-CEL-8876198|dip:DIP-25631N	-	-	-	figure legend:Fig 8f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2012/01/03	2014/10/16	rogid:h1D5aAR/42LZEGamNt9ibHcovUg6239	rogid:k3oGrJUWh+RqwyXoWrq00tnnwjg6239	intact-crc:59182EF299FA3FE7|rigid:hbJ9rEYmyg/1DYlVW2GFuDzxBMg	false	-	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)