#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P05094-2	uniprotkb:Q04584	intact:EBI-6049246|ensembl:ENSGALP00000051864	intact:EBI-6222189|ensembl:ENSGALP00000023626|ensembl:ENSGALP00000074295	psi-mi:p05094-2(display_long)|uniprotkb:Smooth muscle(isoform synonym)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)	psi-mi:zyx_chick(display_long)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:"MI:0071"(molecular sieving)	Crawford et al. (1992)	pubmed:1541635|imex:IM-18816	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6222187|imex:IM-18816-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5847257(isoform-parent)|ensembl:ENSGALG00000042458(gene)|ensembl:ENSGALT00000061392(transcript)	ensembl:ENSGALG00000014688(gene)|ensembl:ENSGALT00000023672(transcript)|ensembl:ENSGALT00000099039(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_001004386.1	-	-	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/12	2014/10/16	rogid:WBHBWvUY5lAGxeN/EHyCu44PqqY9031	rogid:v0+i/KilPJGvFwhGYm/bq5qboBM9031	intact-crc:2C1B9931D3F94ADC|rigid:WZoRLLi4S3iz0DRp6kn7ZtNJONA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q04584	uniprotkb:P05094-2	intact:EBI-6222189|ensembl:ENSGALP00000023626|ensembl:ENSGALP00000074295	intact:EBI-6049246|ensembl:ENSGALP00000051864	psi-mi:zyx_chick(display_long)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:p05094-2(display_long)|uniprotkb:Smooth muscle(isoform synonym)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Crawford et al. (1992)	pubmed:1541635|imex:IM-18816	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6222254|imex:IM-18816-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSGALG00000014688(gene)|ensembl:ENSGALT00000023672(transcript)|ensembl:ENSGALT00000099039(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_001004386.1	intact:EBI-5847257(isoform-parent)|ensembl:ENSGALG00000042458(gene)|ensembl:ENSGALT00000061392(transcript)	-	-	-	figure legend:Fig. 3B& 4B|comment:Purified alpha-actinin was used in Fig 3B, while a mixture of proteins from chick gizzard extracts was used in Fig 4B.|comment:"Zyxin binds to the 27kDa fragment of alpha-actinin-1, but not the 53 kDa fragment.(Fig.3B)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/12	2014/10/16	rogid:v0+i/KilPJGvFwhGYm/bq5qboBM9031	rogid:WBHBWvUY5lAGxeN/EHyCu44PqqY9031	intact-crc:321D90611C903C9B|rigid:WZoRLLi4S3iz0DRp6kn7ZtNJONA	false	125i radiolabel:?-?	-	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P05094-2	uniprotkb:Q04584	intact:EBI-6049246|ensembl:ENSGALP00000051864	intact:EBI-6222189|ensembl:ENSGALP00000023626|ensembl:ENSGALP00000074295	psi-mi:p05094-2(display_long)|uniprotkb:Smooth muscle(isoform synonym)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)	psi-mi:zyx_chick(display_long)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:"MI:0047"(far western blotting)	Crawford et al. (1992)	pubmed:1541635|imex:IM-18816	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6222482|imex:IM-18816-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5847257(isoform-parent)|ensembl:ENSGALG00000042458(gene)|ensembl:ENSGALT00000061392(transcript)	ensembl:ENSGALG00000014688(gene)|ensembl:ENSGALT00000023672(transcript)|ensembl:ENSGALT00000099039(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_001004386.1	-	-	-	figure legend:Fig. 5B|comment:The heat denatured alpha-actinin does not bind zyxin.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/12	2014/10/16	rogid:WBHBWvUY5lAGxeN/EHyCu44PqqY9031	rogid:v0+i/KilPJGvFwhGYm/bq5qboBM9031	intact-crc:6B159A4F3AA7FF0B|rigid:WZoRLLi4S3iz0DRp6kn7ZtNJONA	false	125i radiolabel:?-?	-	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:Q04584	uniprotkb:P05094-2	intact:EBI-6222189|ensembl:ENSGALP00000023626|ensembl:ENSGALP00000074295	intact:EBI-6049246|ensembl:ENSGALP00000051864	psi-mi:zyx_chick(display_long)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:p05094-2(display_long)|uniprotkb:Smooth muscle(isoform synonym)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)	psi-mi:"MI:0892"(solid phase assay)	Crawford et al. (1992)	pubmed:1541635|imex:IM-18816	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6222838|imex:IM-18816-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSGALG00000014688(gene)|ensembl:ENSGALT00000023672(transcript)|ensembl:ENSGALT00000099039(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_001004386.1	intact:EBI-5847257(isoform-parent)|ensembl:ENSGALG00000042458(gene)|ensembl:ENSGALT00000061392(transcript)	-	-	-	figure legend:Fig. 6 & 7A,B|comment:"The association between zyxin and 125 i-alpha-actinin was competitively inhibited by unlabeled alpha-actinin (Fig. 6&7a)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.07x10^-6 ~0.31(molar)	2012/07/12	2014/10/16	rogid:v0+i/KilPJGvFwhGYm/bq5qboBM9031	rogid:WBHBWvUY5lAGxeN/EHyCu44PqqY9031	intact-crc:9BFE89110A62CE7D|rigid:WZoRLLi4S3iz0DRp6kn7ZtNJONA	false	-	125i radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)