#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7TSU1 uniprotkb:P15431 intact:EBI-6257913|ensembl:ENSRNOP00000010054 intact:EBI-6257992|ensembl:ENSRNOP00000003170 psi-mi:big2_rat(display_long)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)|uniprotkb:Arfgep2(gene name synonym)|uniprotkb:Arfgef2(gene name)|psi-mi:Arfgef2(display_short)|uniprotkb:Big2(gene name synonym) psi-mi:gbrb1_rat(display_long)|uniprotkb:Gabrb1(gene name)|psi-mi:Gabrb1(display_short)|uniprotkb:Gabrb-1(gene name synonym)|uniprotkb:"GABA(A) receptor subunit beta-1"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Charych et al. (2004) pubmed:15198677|imex:IM-17621 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6257990|imex:IM-17621-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000007485(gene)|ensembl:ENSRNOT00000010054(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rgd:631430|refseq:NP_851597.2 ensembl:ENSRNOG00000002327(gene)|ensembl:ENSRNOT00000003170(transcript)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005253"(anion channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042698"(ovulation cycle)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0050877"(nervous system process)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR002289(Gamma-aminobutyric-acid A receptor, beta subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|rcsb pdb:6DW0|rcsb pdb:6DW1|reactome:R-RNO-977443|rgd:2649|refseq:NP_037088.1 - - - figure legend:2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/07/31 2014/10/16 rogid:s/OkSNCX9gWVx8jcSXA8uwIZqhk10116 rogid:hNkNxC6TJ3cgvbNED9Gwlz/9PmA10116 intact-crc:EF3A70C0A9FF4296|rigid:Q+rOCjKovMI0udJJk8KqhqwWNjQ false sufficient binding region:1682-1791 sufficient binding region:328-451 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63079 uniprotkb:Q7TSU1 intact:EBI-6257937|uniprotkb:P15433 intact:EBI-6257913|ensembl:ENSRNOP00000010054 psi-mi:gbrb3_rat(display_long)|uniprotkb:Gabrb3(gene name)|psi-mi:Gabrb3(display_short)|uniprotkb:Gabrb-3(gene name synonym)|uniprotkb:"GABA(A) receptor subunit beta-3"(gene name synonym) psi-mi:big2_rat(display_long)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)|uniprotkb:Arfgep2(gene name synonym)|uniprotkb:Arfgef2(gene name)|psi-mi:Arfgef2(display_short)|uniprotkb:Big2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Charych et al. (2004) pubmed:15198677|imex:IM-17621 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6257978|imex:IM-17621-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0009986"(cell surface)|go:"GO:0019098"(reproductive behavior)|go:"GO:0021549"(cerebellum development)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0035176"(social behavior)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042493"|go:"GO:0042747"(circadian sleep/wake cycle, REM sleep)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048666"(neuron development)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060022"(hard palate development)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060384"(innervation)|go:"GO:0061744"(motor behavior)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072347"(response to anesthetic)|go:"GO:0090102"(cochlea development)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR002289(Gamma-aminobutyric-acid A receptor, beta subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005254"(chloride channel activity)|rgd:2651|refseq:NP_058761.1|dip:DIP-60770N|reactome:R-RNO-977443 ensembl:ENSRNOG00000007485(gene)|ensembl:ENSRNOT00000010054(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rgd:631430|refseq:NP_851597.2 - - - figure legend:2b and c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/07/31 2014/10/16 rogid:spsRtfvYAMijH8+WsdGVwHwu+Jo10116 rogid:s/OkSNCX9gWVx8jcSXA8uwIZqhk10116 intact-crc:37AB0D46A445E60E|rigid:slzHdNivjdT4VelSceMZLjh7Gt4 false necessary binding region:328-345 necessary binding region:1682-1791 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7TSU1 uniprotkb:P63138 intact:EBI-6257913|ensembl:ENSRNOP00000010054 intact:EBI-6258047|ensembl:ENSRNOP00000004970|uniprotkb:P15432 psi-mi:big2_rat(display_long)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)|uniprotkb:Arfgep2(gene name synonym)|uniprotkb:Arfgef2(gene name)|psi-mi:Arfgef2(display_short)|uniprotkb:Big2(gene name synonym) psi-mi:gbrb2_rat(display_long)|uniprotkb:Gabrb2(gene name)|psi-mi:Gabrb2(display_short)|uniprotkb:Gabrb-2(gene name synonym)|uniprotkb:"GABA(A) receptor subunit beta-2"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Charych et al. (2004) pubmed:15198677|imex:IM-17621 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6258080|imex:IM-17621-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000007485(gene)|ensembl:ENSRNOT00000010054(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rgd:631430|refseq:NP_851597.2 ensembl:ENSRNOG00000003680(gene)|ensembl:ENSRNOT00000004970(transcript)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016020"(membrane)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048666"(neuron development)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060384"(innervation)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0090102"(cochlea development)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902710"(GABA receptor complex)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR002289(Gamma-aminobutyric-acid A receptor, beta subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-RNO-977443|refseq:XP_006246189.1|rgd:2650|refseq:NP_037089.1 - - - figure legend:2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/07/31 2014/10/16 rogid:s/OkSNCX9gWVx8jcSXA8uwIZqhk10116 rogid:nGZutwYQuco9YJNkPqdZdxDdEhI10116 intact-crc:5659524D670664A8|rigid:p4W2VH9uFi3fDZpyCBgP/2EVhvo false sufficient binding region:1682-1791 sufficient binding region:327-451 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7TSU1 uniprotkb:P63079 intact:EBI-6257913|ensembl:ENSRNOP00000010054 intact:EBI-6257937|uniprotkb:P15433 psi-mi:big2_rat(display_long)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)|uniprotkb:Arfgep2(gene name synonym)|uniprotkb:Arfgef2(gene name)|psi-mi:Arfgef2(display_short)|uniprotkb:Big2(gene name synonym) psi-mi:gbrb3_rat(display_long)|uniprotkb:Gabrb3(gene name)|psi-mi:Gabrb3(display_short)|uniprotkb:Gabrb-3(gene name synonym)|uniprotkb:"GABA(A) receptor subunit beta-3"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Charych et al. (2004) pubmed:15198677|imex:IM-17621 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6257911|imex:IM-17621-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000007485(gene)|ensembl:ENSRNOT00000010054(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rgd:631430|refseq:NP_851597.2 go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0009986"(cell surface)|go:"GO:0019098"(reproductive behavior)|go:"GO:0021549"(cerebellum development)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0035176"(social behavior)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042493"|go:"GO:0042747"(circadian sleep/wake cycle, REM sleep)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048666"(neuron development)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060022"(hard palate development)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060384"(innervation)|go:"GO:0061744"(motor behavior)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072347"(response to anesthetic)|go:"GO:0090102"(cochlea development)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR002289(Gamma-aminobutyric-acid A receptor, beta subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005254"(chloride channel activity)|rgd:2651|refseq:NP_058761.1|dip:DIP-60770N|reactome:R-RNO-977443 - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/07/31 2014/10/16 rogid:s/OkSNCX9gWVx8jcSXA8uwIZqhk10116 rogid:spsRtfvYAMijH8+WsdGVwHwu+Jo10116 intact-crc:2A989D3AC0E67643|rigid:slzHdNivjdT4VelSceMZLjh7Gt4 false sufficient binding region:1682-1791 sufficient binding region:328-450 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P63079 uniprotkb:Q7TSU1 intact:EBI-6257937|uniprotkb:P15433 intact:EBI-6257913|ensembl:ENSRNOP00000010054 psi-mi:gbrb3_rat(display_long)|uniprotkb:Gabrb3(gene name)|psi-mi:Gabrb3(display_short)|uniprotkb:Gabrb-3(gene name synonym)|uniprotkb:"GABA(A) receptor subunit beta-3"(gene name synonym) psi-mi:big2_rat(display_long)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)|uniprotkb:Arfgep2(gene name synonym)|uniprotkb:Arfgef2(gene name)|psi-mi:Arfgef2(display_short)|uniprotkb:Big2(gene name synonym) psi-mi:"MI:0047"(far western blotting) Charych et al. (2004) pubmed:15198677|imex:IM-17621 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-6258171|imex:IM-17621-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0009986"(cell surface)|go:"GO:0019098"(reproductive behavior)|go:"GO:0021549"(cerebellum development)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0035176"(social behavior)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042493"|go:"GO:0042747"(circadian sleep/wake cycle, REM sleep)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048666"(neuron development)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060022"(hard palate development)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060384"(innervation)|go:"GO:0061744"(motor behavior)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072347"(response to anesthetic)|go:"GO:0090102"(cochlea development)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR002289(Gamma-aminobutyric-acid A receptor, beta subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005254"(chloride channel activity)|rgd:2651|refseq:NP_058761.1|dip:DIP-60770N|reactome:R-RNO-977443 ensembl:ENSRNOG00000007485(gene)|ensembl:ENSRNOT00000010054(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rgd:631430|refseq:NP_851597.2 - - - figure legend:3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/31 2014/10/16 rogid:spsRtfvYAMijH8+WsdGVwHwu+Jo10116 rogid:s/OkSNCX9gWVx8jcSXA8uwIZqhk10116 intact-crc:E96D8F5C55621584|rigid:slzHdNivjdT4VelSceMZLjh7Gt4 false his tag:n-n glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62813 uniprotkb:Q7TSU1 intact:EBI-6258192|ensembl:ENSRNOP00000004725|uniprotkb:P18504|uniprotkb:Q53YK4 intact:EBI-6257913|ensembl:ENSRNOP00000010054 psi-mi:gbra1_rat(display_long)|uniprotkb:Gabra1(gene name)|psi-mi:Gabra1(display_short)|uniprotkb:Gabra-1(gene name synonym)|uniprotkb:"GABA(A) receptor subunit alpha-1"(gene name synonym) psi-mi:big2_rat(display_long)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)|uniprotkb:Arfgep2(gene name synonym)|uniprotkb:Arfgef2(gene name)|psi-mi:Arfgef2(display_short)|uniprotkb:Big2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Charych et al. (2004) pubmed:15198677|imex:IM-17621 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6258190|imex:IM-17621-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000003512(gene)|ensembl:ENSRNOT00000004725(transcript)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016020"(membrane)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050809"(diazepam binding)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902710"(GABA receptor complex)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR001390(Gamma-aminobutyric-acid A receptor, alpha subunit)|interpro:IPR005431(Gamma-aminobutyric-acid A receptor, alpha 1 subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|mint:P62813|rcsb pdb:6DW0|rcsb pdb:6DW1|reactome:R-RNO-977443|refseq:XP_006246185.1|refseq:XP_006246186.1|rgd:61855|refseq:NP_899155.1|refseq:XP_017452668.1 ensembl:ENSRNOG00000007485(gene)|ensembl:ENSRNOT00000010054(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rgd:631430|refseq:NP_851597.2 - - - figure legend:3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-brain-hippocampus)|taxid:10116(Hippocampus of rat brain) - 2012/07/31 2014/10/16 rogid:7l4wzGez8m0Cu7ImDN+J2BKurwg10116 rogid:s/OkSNCX9gWVx8jcSXA8uwIZqhk10116 intact-crc:2DC08623FA15E853|rigid:suZ//1KRl2gNolVFbB31gtqlXp0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7TSU1 uniprotkb:P14867 intact:EBI-6257913|ensembl:ENSRNOP00000010054 intact:EBI-6258308|ensembl:ENSP00000023897|ensembl:ENSP00000377517|ensembl:ENSP00000393097|ensembl:ENSP00000415441|ensembl:ENSP00000489738|ensembl:ENSP00000489839|ensembl:ENSP00000490320|ensembl:ENSP00000490804|uniprotkb:D3DQK6|uniprotkb:Q8N629 psi-mi:big2_rat(display_long)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)|uniprotkb:Arfgep2(gene name synonym)|uniprotkb:Arfgef2(gene name)|psi-mi:Arfgef2(display_short)|uniprotkb:Big2(gene name synonym) psi-mi:gbra1_human(display_long)|uniprotkb:GABRA1(gene name)|psi-mi:GABRA1(display_short)|uniprotkb:"GABA(A) receptor subunit alpha-1"(gene name synonym) psi-mi:"MI:0428"(imaging technique) Charych et al. (2004) pubmed:15198677|imex:IM-17621 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6258248|imex:IM-17621-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000007485(gene)|ensembl:ENSRNOT00000010054(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rgd:631430|refseq:NP_851597.2 go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050809"(diazepam binding)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902710"(GABA receptor complex)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR001390(Gamma-aminobutyric-acid A receptor, alpha subunit)|interpro:IPR005431(Gamma-aminobutyric-acid A receptor, alpha 1 subunit)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|rcsb pdb:6CDU|rcsb pdb:6D1S|rcsb pdb:6D6T|rcsb pdb:6D6U|rcsb pdb:6HUG|rcsb pdb:6HUJ|rcsb pdb:6HUK|rcsb pdb:6HUO|rcsb pdb:6HUP|rcsb pdb:6I53|rcsb pdb:6X3S|rcsb pdb:6X3T|rcsb pdb:6X3U|rcsb pdb:6X3V|rcsb pdb:6X3W|rcsb pdb:6X3X|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|rcsb pdb:6X3Z|rcsb pdb:6X40|reactome:R-HSA-1236394|reactome:R-HSA-977443|ensembl:ENSG00000022355(gene)|ensembl:ENST00000023897(transcript)|ensembl:ENST00000393943(transcript)|ensembl:ENST00000428797(transcript)|ensembl:ENST00000437025(transcript)|ensembl:ENST00000635880(transcript)|ensembl:ENST00000636573(transcript)|ensembl:ENST00000637827(transcript)|ensembl:ENST00000638112(transcript)|refseq:NP_000797.2|refseq:NP_001121115.1|refseq:NP_001121116.1|refseq:NP_001121117.1|refseq:NP_001121120.1 go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/07/31 2014/10/16 rogid:s/OkSNCX9gWVx8jcSXA8uwIZqhk10116 rogid:6wrRTf2MOYgoKk0RgswgfaI5d+c9606 intact-crc:167EF82D2198A9E3|rigid:fDumFnqF6peTfjsh0DkPf/LEebM false ha tag:n-n|sufficient binding region:1682-1791 - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q7TSU1 uniprotkb:P28472 intact:EBI-6257913|ensembl:ENSRNOP00000010054 intact:EBI-6258252|ensembl:ENSP00000308725|uniprotkb:B7Z2W1|uniprotkb:H7BYV8|uniprotkb:Q14352|uniprotkb:Q96FM5|uniprotkb:B7Z825|uniprotkb:F5H3D2 psi-mi:big2_rat(display_long)|uniprotkb:ADP-ribosylation factor guanine nucleotide-exchange factor 2(gene name synonym)|uniprotkb:Arfgep2(gene name synonym)|uniprotkb:Arfgef2(gene name)|psi-mi:Arfgef2(display_short)|uniprotkb:Big2(gene name synonym) psi-mi:gbrb3_human(display_long)|uniprotkb:GABRB3(gene name)|psi-mi:GABRB3(display_short)|uniprotkb:"GABA(A) receptor subunit beta-3"(gene name synonym) psi-mi:"MI:0428"(imaging technique) Charych et al. (2004) pubmed:15198677|imex:IM-17621 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6258248|imex:IM-17621-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000007485(gene)|ensembl:ENSRNOT00000010054(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007032"(endosome organization)|go:"GO:0010256"(endomembrane system organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032280"(symmetric synapse)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0055037"(recycling endosome)|interpro:IPR000904(SEC7-like)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|interpro:IPR023394|interpro:IPR032629|interpro:IPR032691|interpro:IPR035999|rgd:631430|refseq:NP_851597.2 ensembl:ENSG00000166206(gene)|ensembl:ENST00000311550(transcript)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050877"(nervous system process)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071420"(cellular response to histamine)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR002289(Gamma-aminobutyric-acid A receptor, beta subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|rcsb pdb:4COF|rcsb pdb:5O8F|rcsb pdb:5OJM|rcsb pdb:6A96|rcsb pdb:6HUG|rcsb pdb:6HUJ|rcsb pdb:6HUK|rcsb pdb:6HUO|rcsb pdb:6HUP|rcsb pdb:6I53|reactome:R-HSA-1236394|reactome:R-HSA-977443|refseq:NP_000805.1|refseq:NP_001178249.1|refseq:NP_001178250.1|refseq:NP_068712.1|refseq:NP_001265560.1|dip:DIP-61029N go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/07/31 2014/10/16 rogid:s/OkSNCX9gWVx8jcSXA8uwIZqhk10116 rogid:dgZJaPbhb7B3CLAyyV4O3jrEiHw9606 intact-crc:167EF82D2198A9E3|rigid:fDumFnqF6peTfjsh0DkPf/LEebM false ha tag:n-n|sufficient binding region:1682-1791 - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)