#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:F8VQB6	uniprotkb:P18084	intact:EBI-6445959|uniprotkb:Q8R3S0|uniprotkb:Q9JJY5|ensembl:ENSMUSP00000106087	intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181	psi-mi:myo10_mouse(display_long)|uniprotkb:Myo10(gene name)|psi-mi:Myo10(display_short)|uniprotkb:Unconventional myosin-10(gene name synonym)	psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2004)	imex:IM-18841|pubmed:15156152	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6445957|imex:IM-18841-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000022272(gene)|ensembl:ENSMUST00000110457(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016459"(myosin complex)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030507"(spectrin binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060002"(plus-end directed microfilament motor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR031971|interpro:IPR035963|interpro:IPR036124|interpro:IPR036961|interpro:IPR038185|interpro:IPR040640|interpro:IPR041797|reactome:R-MMU-2029482|refseq:NP_062345.2|refseq:XP_006520088.1	refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355	-	-	-	figure legend:"Text reference (p 529)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/12/10	2014/10/16	rogid:FjRMmaaoqmy1xIhpHA/QyPoNhpE10090	rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606	intact-crc:44545D1BEC123DA5|rigid:vKkHQlQVdXhkG2IuxzjBT6H41/w	false	-	sufficient binding region:753-799	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:F8VQB6	uniprotkb:P18084	intact:EBI-6445959|uniprotkb:Q8R3S0|uniprotkb:Q9JJY5|ensembl:ENSMUSP00000106087	intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181	psi-mi:myo10_mouse(display_long)|uniprotkb:Myo10(gene name)|psi-mi:Myo10(display_short)|uniprotkb:Unconventional myosin-10(gene name synonym)	psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2004)	imex:IM-18841|pubmed:15156152	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6446012|imex:IM-18841-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000022272(gene)|ensembl:ENSMUST00000110457(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016459"(myosin complex)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030507"(spectrin binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060002"(plus-end directed microfilament motor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR031971|interpro:IPR035963|interpro:IPR036124|interpro:IPR036961|interpro:IPR038185|interpro:IPR040640|interpro:IPR041797|reactome:R-MMU-2029482|refseq:NP_062345.2|refseq:XP_006520088.1	refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355	-	-	-	figure legend:Fig 1a, S2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/12/10	2014/10/16	rogid:FjRMmaaoqmy1xIhpHA/QyPoNhpE10090	rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606	intact-crc:1824CC3216B8800A|rigid:vKkHQlQVdXhkG2IuxzjBT6H41/w	false	sufficient binding region:1551-2048	mutation disrupting interaction:772-772|sufficient binding region:763-777|mutation disrupting interaction:774-774|mutation decreasing interaction:773-773	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P79114	uniprotkb:F1MTN1	intact:EBI-6429973	intact:EBI-6446031|ensembl:ENSBTAP00000013173	psi-mi:myo10_bovin(display_long)|uniprotkb:MYO10(gene name)|psi-mi:MYO10(display_short)|uniprotkb:Unconventional myosin-10(gene name synonym)	psi-mi:f1mtn1_bovin(display_long)|uniprotkb:ITGB3(gene name)|psi-mi:ITGB3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhang et al. (2004)	imex:IM-18841|pubmed:15156152	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6446029|imex:IM-18841-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0016459"(myosin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060002"(plus-end directed microfilament motor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR031971|interpro:IPR035963|interpro:IPR036124|interpro:IPR036961|interpro:IPR038185|interpro:IPR040640|interpro:IPR041797|rcsb pdb:2N9B|rcsb pdb:5HMO|rcsb pdb:6HR1|go:"GO:0008360"(regulation of cell shape)|refseq:NP_776819.1|dip:DIP-46150N	ensembl:ENSBTAG00000009987(gene)|ensembl:ENSBTAT00000013173(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005768"(endosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035866"(alphav-beta3 integrin-PKCalpha complex)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051611"(regulation of serotonin uptake)|go:"GO:0061097"(regulation of protein tyrosine kinase activity)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071133"(alpha9-beta1 integrin-ADAM8 complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903053"(regulation of extracellular matrix organization)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR013111(EGF, extracellular)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027068|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|reactome:R-BTA-114608|reactome:R-BTA-354192|refseq:NP_001193419.1	-	-	-	figure legend:Fig 1d.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin-pulmonary_artery)|taxid:9913(Bos taurus pulmonary artery cells)	-	2012/12/10	2014/10/16	rogid:NFHVGvUG5NbIBnwiJicR8BImJqQ9913	rogid:6hgG1FPhA3P7AkIUBYSqlsr2E9o9913	intact-crc:E0287ABA371434F7|rigid:Q6NImWfCOO3IbONCT5BymccSUic	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P79114	uniprotkb:F1MTN1	intact:EBI-6429973	intact:EBI-6446031|ensembl:ENSBTAP00000013173	psi-mi:myo10_bovin(display_long)|uniprotkb:MYO10(gene name)|psi-mi:MYO10(display_short)|uniprotkb:Unconventional myosin-10(gene name synonym)	psi-mi:f1mtn1_bovin(display_long)|uniprotkb:ITGB3(gene name)|psi-mi:ITGB3(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Zhang et al. (2004)	imex:IM-18841|pubmed:15156152	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6446065|imex:IM-18841-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0016459"(myosin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060002"(plus-end directed microfilament motor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR031971|interpro:IPR035963|interpro:IPR036124|interpro:IPR036961|interpro:IPR038185|interpro:IPR040640|interpro:IPR041797|rcsb pdb:2N9B|rcsb pdb:5HMO|rcsb pdb:6HR1|go:"GO:0008360"(regulation of cell shape)|refseq:NP_776819.1|dip:DIP-46150N	ensembl:ENSBTAG00000009987(gene)|ensembl:ENSBTAT00000013173(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005768"(endosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035866"(alphav-beta3 integrin-PKCalpha complex)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051611"(regulation of serotonin uptake)|go:"GO:0061097"(regulation of protein tyrosine kinase activity)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071133"(alpha9-beta1 integrin-ADAM8 complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903053"(regulation of extracellular matrix organization)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR013111(EGF, extracellular)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027068|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|reactome:R-BTA-114608|reactome:R-BTA-354192|refseq:NP_001193419.1	go:"GO:0030027"(lamellipodium)	-	-	figure legend:Fig 1f.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin-pulmonary_artery)|taxid:9913(Bos taurus pulmonary artery cells)	-	2012/12/10	2014/10/16	rogid:NFHVGvUG5NbIBnwiJicR8BImJqQ9913	rogid:6hgG1FPhA3P7AkIUBYSqlsr2E9o9913	intact-crc:D8A7A18B9BE78F2A|rigid:Q6NImWfCOO3IbONCT5BymccSUic	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:F1MTN1	uniprotkb:P80746	intact:EBI-6446031|ensembl:ENSBTAP00000013173	intact:EBI-6446072|uniprotkb:Q0PDN6|uniprotkb:Q9GK48|uniprotkb:Q9MZD6	psi-mi:f1mtn1_bovin(display_long)|uniprotkb:ITGB3(gene name)|psi-mi:ITGB3(display_short)	psi-mi:itav_bovin(display_long)|uniprotkb:ITGAV(gene name)|psi-mi:ITGAV(display_short)|uniprotkb:Vitronectin receptor subunit alpha(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Zhang et al. (2004)	imex:IM-18841|pubmed:15156152	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6446070|imex:IM-18841-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAG00000009987(gene)|ensembl:ENSBTAT00000013173(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005768"(endosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035866"(alphav-beta3 integrin-PKCalpha complex)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051611"(regulation of serotonin uptake)|go:"GO:0061097"(regulation of protein tyrosine kinase activity)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071133"(alpha9-beta1 integrin-ADAM8 complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903053"(regulation of extracellular matrix organization)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR013111(EGF, extracellular)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027068|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|reactome:R-BTA-114608|reactome:R-BTA-354192|refseq:NP_001193419.1	go:"GO:0001568"(blood vessel development)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034685"(integrin alphav-beta6 complex)|go:"GO:0034686"(integrin alphav-beta8 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:1901388"(regulation of transforming growth factor beta activation)|interpro:IPR032695|refseq:NP_776792.1|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994	go:"GO:0032433"(filopodium tip)	-	-	figure legend:Fig 1e.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin-pulmonary_artery)|taxid:9913(Bos taurus pulmonary artery cells)	-	2012/12/10	2014/10/16	rogid:6hgG1FPhA3P7AkIUBYSqlsr2E9o9913	rogid:zL79Fw/vf/kVusd0edgngC/HnlQ9913	intact-crc:0B7B0D86FE932869|rigid:WpiEZw7kXgWVboQA9u1Xb+c84xw	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:F1MTN1	uniprotkb:P79114	intact:EBI-6446031|ensembl:ENSBTAP00000013173	intact:EBI-6429973	psi-mi:f1mtn1_bovin(display_long)|uniprotkb:ITGB3(gene name)|psi-mi:ITGB3(display_short)	psi-mi:myo10_bovin(display_long)|uniprotkb:MYO10(gene name)|psi-mi:MYO10(display_short)|uniprotkb:Unconventional myosin-10(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Zhang et al. (2004)	imex:IM-18841|pubmed:15156152	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6446070|imex:IM-18841-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAG00000009987(gene)|ensembl:ENSBTAT00000013173(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005768"(endosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035866"(alphav-beta3 integrin-PKCalpha complex)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051611"(regulation of serotonin uptake)|go:"GO:0061097"(regulation of protein tyrosine kinase activity)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071133"(alpha9-beta1 integrin-ADAM8 complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903053"(regulation of extracellular matrix organization)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR013111(EGF, extracellular)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027068|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|reactome:R-BTA-114608|reactome:R-BTA-354192|refseq:NP_001193419.1	go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0016459"(myosin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060002"(plus-end directed microfilament motor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR031971|interpro:IPR035963|interpro:IPR036124|interpro:IPR036961|interpro:IPR038185|interpro:IPR040640|interpro:IPR041797|rcsb pdb:2N9B|rcsb pdb:5HMO|rcsb pdb:6HR1|go:"GO:0008360"(regulation of cell shape)|refseq:NP_776819.1|dip:DIP-46150N	go:"GO:0032433"(filopodium tip)	-	-	figure legend:Fig 1e.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9913(bovin-pulmonary_artery)|taxid:9913(Bos taurus pulmonary artery cells)	-	2012/12/10	2014/10/16	rogid:6hgG1FPhA3P7AkIUBYSqlsr2E9o9913	rogid:NFHVGvUG5NbIBnwiJicR8BImJqQ9913	intact-crc:0B7B0D86FE932869|rigid:WpiEZw7kXgWVboQA9u1Xb+c84xw	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P18084	uniprotkb:P79114	intact:EBI-1223434|uniprotkb:B0LPF8|uniprotkb:B2RD70|ensembl:ENSP00000296181	intact:EBI-6429973	psi-mi:itb5_human(display_long)|uniprotkb:ITGB5(gene name)|psi-mi:ITGB5(display_short)	psi-mi:myo10_bovin(display_long)|uniprotkb:MYO10(gene name)|psi-mi:MYO10(display_short)|uniprotkb:Unconventional myosin-10(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Zhang et al. (2004)	imex:IM-18841|pubmed:15156152	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6446106|imex:IM-18841-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002204.2|ensembl:ENSG00000082781(gene)|ensembl:ENST00000296181(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034684"(integrin alphav-beta5 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043235"(receptor complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027067|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P18084|reactome:R-HSA-1236973|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-445355	go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0016459"(myosin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060002"(plus-end directed microfilament motor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR031971|interpro:IPR035963|interpro:IPR036124|interpro:IPR036961|interpro:IPR038185|interpro:IPR040640|interpro:IPR041797|rcsb pdb:2N9B|rcsb pdb:5HMO|rcsb pdb:6HR1|go:"GO:0008360"(regulation of cell shape)|refseq:NP_776819.1|dip:DIP-46150N	-	-	-	figure legend:Fig 2b.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/10	2014/10/16	rogid:AKEnIHjRIjtfCHSUvpAkkWZFAu89606	rogid:NFHVGvUG5NbIBnwiJicR8BImJqQ9913	intact-crc:B4910B0B03F8559C|rigid:eJP58V/Sd+E1IPYTzUmnAVxe88o	false	mutation disrupting interaction:772-772|sufficient binding region:763-782	32p radiolabel:?-?|glutathione s tranferase tag:?-?|sufficient binding region:1696-2052	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P79114	uniprotkb:P05556	intact:EBI-6429973	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	psi-mi:myo10_bovin(display_long)|uniprotkb:MYO10(gene name)|psi-mi:MYO10(display_short)|uniprotkb:Unconventional myosin-10(gene name synonym)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Zhang et al. (2004)	imex:IM-18841|pubmed:15156152	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6449277|imex:IM-18841-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0016459"(myosin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060002"(plus-end directed microfilament motor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR031971|interpro:IPR035963|interpro:IPR036124|interpro:IPR036961|interpro:IPR038185|interpro:IPR040640|interpro:IPR041797|rcsb pdb:2N9B|rcsb pdb:5HMO|rcsb pdb:6HR1|go:"GO:0008360"(regulation of cell shape)|refseq:NP_776819.1|dip:DIP-46150N	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191	-	-	-	figure legend:Fig S1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/12/10	2014/10/16	rogid:NFHVGvUG5NbIBnwiJicR8BImJqQ9913	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	intact-crc:BCF3BA19185C17B0|rigid:M7PoUULCbacqqNPhXD0jsmVd6JI	false	sufficient binding region:1744-2052|green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P05106	uniprotkb:P79114	intact:EBI-702847|uniprotkb:A0PJW2|uniprotkb:O15495|uniprotkb:Q12806|uniprotkb:Q13413|uniprotkb:Q14648|uniprotkb:Q16499|uniprotkb:D3DXJ8|ensembl:ENSP00000452786	intact:EBI-6429973	psi-mi:itb3_human(display_long)|uniprotkb:Platelet membrane glycoprotein IIIa(gene name synonym)|uniprotkb:ITGB3(gene name)|psi-mi:ITGB3(display_short)|uniprotkb:GP3A(gene name synonym)	psi-mi:myo10_bovin(display_long)|uniprotkb:MYO10(gene name)|psi-mi:MYO10(display_short)|uniprotkb:Unconventional myosin-10(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Zhang et al. (2004)	imex:IM-18841|pubmed:15156152	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6449303|imex:IM-18841-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000203.2|dip:DIP-304N|ensembl:ENSG00000259207(gene)|ensembl:ENST00000559488(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0008305"(integrin complex)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0035295"(tube development)|go:"GO:0035866"(alphav-beta3 integrin-PKCalpha complex)|go:"GO:0035867"(alphav-beta3 integrin-IGF-1-IGF1R complex)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043184"(vascular endothelial growth factor receptor 2 binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050748"(negative regulation of lipoprotein metabolic process)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051611"(regulation of serotonin uptake)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1905598"(negative regulation of low-density lipoprotein receptor activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027068|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05106|rcsb pdb:1JV2|rcsb pdb:1KUP|rcsb pdb:1KUZ|rcsb pdb:1L5G|rcsb pdb:1M1X|rcsb pdb:1M8O|rcsb pdb:1MIZ|rcsb pdb:1MK7|rcsb pdb:1MK9|rcsb pdb:1RN0|rcsb pdb:1S4X|rcsb pdb:1TYE|rcsb pdb:1U8C|rcsb pdb:2INI|rcsb pdb:2K9J|rcsb pdb:2KNC|rcsb pdb:2KV9|rcsb pdb:2L1C|rcsb pdb:2L91|rcsb pdb:2LJD|rcsb pdb:2LJE|rcsb pdb:2LJF|rcsb pdb:2MTP|rcsb pdb:2N9Y|rcsb pdb:2Q6W|rcsb pdb:2RMZ|rcsb pdb:2RN0|rcsb pdb:2VC2|rcsb pdb:2VDK|rcsb pdb:2VDL|rcsb pdb:2VDM|rcsb pdb:2VDN|rcsb pdb:2VDO|rcsb pdb:2VDP|rcsb pdb:2VDQ|rcsb pdb:2VDR|rcsb pdb:3FCS|rcsb pdb:3FCU|rcsb pdb:3IJE|rcsb pdb:3NID|rcsb pdb:3NIF|rcsb pdb:3NIG|rcsb pdb:3T3M|rcsb pdb:3T3P|rcsb pdb:3ZDX|rcsb pdb:3ZDY|rcsb pdb:3ZDZ|rcsb pdb:3ZE0|rcsb pdb:3ZE1|rcsb pdb:3ZE2|rcsb pdb:4CAK|rcsb pdb:4G1E|rcsb pdb:4G1M|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4O02|rcsb pdb:4Z7N|rcsb pdb:4Z7O|rcsb pdb:4Z7Q|rcsb pdb:5HDB|rcsb pdb:6AVQ|rcsb pdb:6AVR|rcsb pdb:6AVU|rcsb pdb:6BXB|rcsb pdb:6BXF|rcsb pdb:6BXJ|rcsb pdb:6CKB|rcsb pdb:6MK0|rcsb pdb:6MSL|rcsb pdb:6MSU|rcsb pdb:6NAJ|rcsb pdb:6V4P|reactome:R-HSA-114608|reactome:R-HSA-1566948|reactome:R-HSA-210990|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223	go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0016459"(myosin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060002"(plus-end directed microfilament motor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR031971|interpro:IPR035963|interpro:IPR036124|interpro:IPR036961|interpro:IPR038185|interpro:IPR040640|interpro:IPR041797|rcsb pdb:2N9B|rcsb pdb:5HMO|rcsb pdb:6HR1|go:"GO:0008360"(regulation of cell shape)|refseq:NP_776819.1|dip:DIP-46150N	go:"GO:0032433"(filopodium tip)	-	-	figure legend:"Fig S3 (a, b)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-melanoma)|taxid:9606(Human melanoma)	-	2012/12/10	2014/10/16	rogid:EnuaoGdEG3SOqzwmTfH1OwqKuzs9606	rogid:NFHVGvUG5NbIBnwiJicR8BImJqQ9913	intact-crc:541A3157D846AAD9|rigid:Nl9Xx+LqHxlG6OH+DFNHuYswBaM	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P79114	uniprotkb:P05556	intact:EBI-6429973	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	psi-mi:myo10_bovin(display_long)|uniprotkb:MYO10(gene name)|psi-mi:MYO10(display_short)|uniprotkb:Unconventional myosin-10(gene name synonym)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Zhang et al. (2004)	imex:IM-18841|pubmed:15156152	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6453046|imex:IM-18841-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0016459"(myosin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060002"(plus-end directed microfilament motor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR031971|interpro:IPR035963|interpro:IPR036124|interpro:IPR036961|interpro:IPR038185|interpro:IPR040640|interpro:IPR041797|rcsb pdb:2N9B|rcsb pdb:5HMO|rcsb pdb:6HR1|go:"GO:0008360"(regulation of cell shape)|refseq:NP_776819.1|dip:DIP-46150N	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191	go:"GO:0032433"(filopodium tip)	-	-	figure legend:Fig S4.|comment:The colocalization of integrin beta-1 with myosin X at filopodial tips was enhanced in GFP-Myo10 transfected HeLa cells, but not in cells transfected with GFP-Myo10-HMM or GFP-Myo10-Tail.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/12/10	2014/10/16	rogid:NFHVGvUG5NbIBnwiJicR8BImJqQ9913	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	intact-crc:962F13AA8C931AF9|rigid:M7PoUULCbacqqNPhXD0jsmVd6JI	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)