#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q53EK2 uniprotkb:P53692 intact:EBI-605440|ensemblfungi:"SPCC550.05.1:pep" intact:EBI-603745|ensemblfungi:"SPCC5E4.06.1:pep" psi-mi:nse1_schpo(display_long)|uniprotkb:nse1(gene name)|psi-mi:nse1(display_short)|uniprotkb:SPCC550.05(orf name) psi-mi:smc6_schpo(display_long)|uniprotkb:smc6(gene name)|psi-mi:smc6(display_short)|uniprotkb:SPCC5E4.06(orf name)|uniprotkb:DNA repair protein rad18(gene name synonym)|uniprotkb:rad18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harvey et al. (2004) pubmed:14701739 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5529061 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPCC550.05(gene)|ensemblfungi:SPCC550.05.1(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006301"(postreplication repair)|go:"GO:0007127"(meiosis I)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070647"(protein modification by small protein conjugation or removal)|interpro:IPR011513(Nse1 non-SMC component of SMC5-6 complex)|refseq:XP_001713165.1|interpro:IPR014857(Zinc finger, RING-like)|interpro:IPR036388|reactome:R-SPO-3108214 ensemblfungi:SPCC5E4.06(gene)|ensemblfungi:SPCC5E4.06.1(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|refseq:NP_587906.1|rcsb pdb:5MG8|interpro:IPR027132|interpro:IPR027417|reactome:R-SPO-3108214 - - - figure legend:7C|curation depth:mimix curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2012/02/14 2014/10/16 rogid:0TTonqoNe9NMglTtmm5UCfs76Dg284812 rogid:HR1AiIh/nv9Uy2GnXQunJJ98cLo284812 intact-crc:28472ECA5E58ADB3|rigid:2UkyWg9ys5jYjiFGkAscXsWB9P4 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96SB8 uniprotkb:Q8WV22 intact:EBI-605415|ensembl:ENSP00000323439|ensembl:ENSP00000384539|ensembl:ENSP00000404092|uniprotkb:Q05BV4|uniprotkb:Q9H0X3|uniprotkb:Q9H6M0|intact:EBI-2557379|uniprotkb:A8K8Q6|uniprotkb:D6W518 intact:EBI-2557372|uniprotkb:Q9P049|uniprotkb:Q9P045|uniprotkb:D3DWF6|ensembl:ENSP00000355077 psi-mi:smc6_human(display_long)|uniprotkb:SMC6(gene name)|psi-mi:SMC6(display_short)|uniprotkb:SMC6L1(gene name synonym) psi-mi:nse1_human(display_long)|uniprotkb:NSMCE1(gene name)|psi-mi:NSMCE1(display_short)|uniprotkb:HSPC333(orf name)|uniprotkb:HSPC337(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Harvey et al. (2004) pubmed:14701739 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-5529072 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163029(gene)|ensembl:ENST00000351948(transcript)|ensembl:ENST00000402989(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000448223(transcript)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035061"(interchromatin granule)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0090398"(cellular senescence)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0000722"(telomere maintenance via recombination)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR027417|reactome:R-HSA-3108214|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000803"(sex chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|refseq:NP_001135758.1|refseq:NP_078900.1|refseq:XP_016860404.1|dip:DIP-34562N ensembl:ENSG00000169189(gene)|ensembl:ENST00000361439(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006301"(postreplication repair)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011513(Nse1 non-SMC component of SMC5-6 complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014857(Zinc finger, RING-like)|interpro:IPR036388|rcsb pdb:2CT0|rcsb pdb:5HVQ|reactome:R-HSA-3108214|rcsb pdb:5WY5|refseq:NP_659547.2|refseq:XP_006721086.1 - - - figure legend:7D|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/02/14 2014/10/16 rogid:R9LrVYPHjbjxnSUVgDl8e8hqOtg9606 rogid:9U8whAXZYSoYq8QX0aoP5i3FVZg9606 intact-crc:65AD3AC28C35C3BB|rigid:r3UnwVfXYO5j2l5WiKANLGIQOS0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)