#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9H4E5	uniprotkb:P42768	intact:EBI-6285694|ensembl:ENSP00000316729|uniprotkb:Q96KC1	intact:EBI-346375|uniprotkb:Q9BU11|uniprotkb:Q9UNJ9|ensembl:ENSP00000365891	psi-mi:rhoj_human(display_long)|uniprotkb:RHOJ(gene name)|psi-mi:RHOJ(display_short)|uniprotkb:ARHJ(gene name synonym)|uniprotkb:RASL7B(gene name synonym)|uniprotkb:RHOI(gene name synonym)|uniprotkb:TCL(gene name synonym)|uniprotkb:Ras-like protein family member 7B(gene name synonym)|uniprotkb:Tc10-like GTP-binding protein(gene name synonym)	psi-mi:wasp_human(display_long)|uniprotkb:WAS(gene name)|psi-mi:WAS(display_short)|uniprotkb:IMD2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Aspenstrom et al. (2004)	pubmed:14521508|imex:IM-18830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6285692|imex:IM-18830-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000126785(gene)|ensembl:ENST00000316754(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903670"(regulation of sprouting angiogenesis)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-HSA-9013409|refseq:NP_065714.1	refseq:NP_000368.1|dip:DIP-431N|ensembl:ENSG00000015285(gene)|ensembl:ENST00000376701(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0007596"(blood coagulation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008544"(epidermis development)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P42768|rcsb pdb:1CEE|rcsb pdb:1EJ5|rcsb pdb:1T84|rcsb pdb:2A3Z|rcsb pdb:2K42|rcsb pdb:2OT0|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-9664422	-	-	-	figure legend:Fig 7A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/31	2014/10/16	rogid:FhTSp74g5BnJShAOSoqX/UwQuBM9606	rogid:VHtlRNZQYpIU2btQV28coDiNsO09606	intact-crc:28D75B197B1C681E|rigid:ax+5aorpxLfOhLJSGsVAzYKdL4A	false	myc tag:?-?	sufficient binding region:201-321|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P42768	uniprotkb:P15153	intact:EBI-346375|uniprotkb:Q9BU11|uniprotkb:Q9UNJ9|ensembl:ENSP00000365891	intact:EBI-489652|ensembl:ENSP00000249071|uniprotkb:Q9UDJ4	psi-mi:wasp_human(display_long)|uniprotkb:WAS(gene name)|psi-mi:WAS(display_short)|uniprotkb:IMD2(gene name synonym)	psi-mi:rac2_human(display_long)|uniprotkb:p21-Rac2(gene name synonym)|uniprotkb:Small G protein(gene name synonym)|uniprotkb:GX(gene name synonym)|uniprotkb:RAC2(gene name)|psi-mi:RAC2(display_short)	psi-mi:"MI:0096"(pull down)	Aspenstrom et al. (2004)	pubmed:14521508|imex:IM-18830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6285740|imex:IM-18830-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000368.1|dip:DIP-431N|ensembl:ENSG00000015285(gene)|ensembl:ENST00000376701(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0007596"(blood coagulation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008544"(epidermis development)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P42768|rcsb pdb:1CEE|rcsb pdb:1EJ5|rcsb pdb:1T84|rcsb pdb:2A3Z|rcsb pdb:2K42|rcsb pdb:2OT0|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-9664422	go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045453"(bone resorption)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060753"(regulation of mast cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P15153|rcsb pdb:1DS6|rcsb pdb:2W2T|rcsb pdb:2W2V|rcsb pdb:2W2X|reactome:R-HSA-114604|reactome:R-HSA-1222556|go:"GO:0043304"(regulation of mast cell degranulation)|ensembl:ENSG00000128340(gene)|ensembl:ENST00000249071(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010810"(regulation of cell-substrate adhesion)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0005925"(focal adhesion)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-HSA-1257604|refseq:NP_002863.1|reactome:R-HSA-2219530|reactome:R-HSA-4086400|reactome:R-HSA-5668599|reactome:R-HSA-6811558|reactome:R-HSA-9013404|dip:DIP-34291N	-	-	-	figure legend:Fig 7A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/31	2014/10/16	rogid:VHtlRNZQYpIU2btQV28coDiNsO09606	rogid:NYkPt/WNmKM3qAhhaufLCPkc/io9606	intact-crc:811474681B76BD3F|rigid:sR9PoPEdQf/VyAnvOzPTYyfFdxA	false	sufficient binding region:201-321|glutathione s tranferase tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P60763	uniprotkb:P42768	intact:EBI-767084|uniprotkb:O14658|uniprotkb:Q5U0M8|ensembl:ENSP00000304283	intact:EBI-346375|uniprotkb:Q9BU11|uniprotkb:Q9UNJ9|ensembl:ENSP00000365891	psi-mi:rac3_human(display_long)|uniprotkb:p21-Rac3(gene name synonym)|uniprotkb:RAC3(gene name)|psi-mi:RAC3(display_short)	psi-mi:wasp_human(display_long)|uniprotkb:WAS(gene name)|psi-mi:WAS(display_short)|uniprotkb:IMD2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Aspenstrom et al. (2004)	pubmed:14521508|imex:IM-18830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6285750|imex:IM-18830-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005043.1|dip:DIP-33881N|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2C2H|rcsb pdb:2G0N|rcsb pdb:2IC5|rcsb pdb:2OV2|rcsb pdb:2QME|rcsb pdb:6TM1|reactome:R-HSA-4086400|reactome:R-HSA-9013423|ensembl:ENSG00000169750(gene)|ensembl:ENST00000306897(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0012505"(endomembrane system)|go:"GO:0014041"(regulation of neuron maturation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021894"(cerebral cortex GABAergic interneuron development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0030027"(lamellipodium)	refseq:NP_000368.1|dip:DIP-431N|ensembl:ENSG00000015285(gene)|ensembl:ENST00000376701(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0007596"(blood coagulation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008544"(epidermis development)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P42768|rcsb pdb:1CEE|rcsb pdb:1EJ5|rcsb pdb:1T84|rcsb pdb:2A3Z|rcsb pdb:2K42|rcsb pdb:2OT0|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-9664422	-	-	-	figure legend:Fig 7A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/31	2014/10/16	rogid:YWu9Tmqxzxu49RSwmyfhawoOUis9606	rogid:VHtlRNZQYpIU2btQV28coDiNsO09606	intact-crc:E644CF588BC1F81D|rigid:PxmPuzzsAJgLyv5hd4dOyaCg3Mc	false	myc tag:?-?	sufficient binding region:201-321|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P17081	uniprotkb:P42768	intact:EBI-689202|uniprotkb:Q0VGN1|uniprotkb:Q52LS8|uniprotkb:Q53SJ1|uniprotkb:Q6NS39|uniprotkb:Q6P146|uniprotkb:Q7Z480|uniprotkb:D6W5A6|ensembl:ENSP00000238738	intact:EBI-346375|uniprotkb:Q9BU11|uniprotkb:Q9UNJ9|ensembl:ENSP00000365891	psi-mi:rhoq_human(display_long)|uniprotkb:Ras-like protein TC10(gene name synonym)|uniprotkb:Ras-like protein family member 7A(gene name synonym)|uniprotkb:RHOQ(gene name)|psi-mi:RHOQ(display_short)|uniprotkb:ARHQ(gene name synonym)|uniprotkb:RASL7A(gene name synonym)|uniprotkb:TC10(gene name synonym)	psi-mi:wasp_human(display_long)|uniprotkb:WAS(gene name)|psi-mi:WAS(display_short)|uniprotkb:IMD2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Aspenstrom et al. (2004)	pubmed:14521508|imex:IM-18830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6285760|imex:IM-18830-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036381.2|ensembl:ENSG00000119729(gene)|ensembl:ENST00000238738(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005522"(profilin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2ATX|reactome:R-HSA-1445148|reactome:R-HSA-5627083|reactome:R-HSA-9013406	refseq:NP_000368.1|dip:DIP-431N|ensembl:ENSG00000015285(gene)|ensembl:ENST00000376701(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0007596"(blood coagulation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008544"(epidermis development)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P42768|rcsb pdb:1CEE|rcsb pdb:1EJ5|rcsb pdb:1T84|rcsb pdb:2A3Z|rcsb pdb:2K42|rcsb pdb:2OT0|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-9664422	-	-	-	figure legend:Fig 7A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/31	2014/10/16	rogid:+7R9kNHFo4Sk46daCd13CDtKAR09606	rogid:VHtlRNZQYpIU2btQV28coDiNsO09606	intact-crc:84848F109825ADB6|rigid:E4Ap6/LdpwdFplJz403qL3Vy6mg	false	ha tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:201-321	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13153-2	uniprotkb:Q9H4E5	intact:EBI-1019502|ensembl:ENSP00000278568	intact:EBI-6285694|ensembl:ENSP00000316729|uniprotkb:Q96KC1	psi-mi:q13153-2(display_long)|uniprotkb:PAK1B(isoform synonym)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)	psi-mi:rhoj_human(display_long)|uniprotkb:RHOJ(gene name)|psi-mi:RHOJ(display_short)|uniprotkb:ARHJ(gene name synonym)|uniprotkb:RASL7B(gene name synonym)|uniprotkb:RHOI(gene name synonym)|uniprotkb:TCL(gene name synonym)|uniprotkb:Ras-like protein family member 7B(gene name synonym)|uniprotkb:Tc10-like GTP-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Aspenstrom et al. (2004)	pubmed:14521508|imex:IM-18830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6285770|imex:IM-18830-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1307(pak1_human)|uniprotkb:Q13153-2(isoform-parent)|ensembl:ENSG00000149269(gene)|ensembl:ENST00000278568(transcript)	ensembl:ENSG00000126785(gene)|ensembl:ENST00000316754(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903670"(regulation of sprouting angiogenesis)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-HSA-9013409|refseq:NP_065714.1	-	-	-	figure legend:Fig 7A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/31	2014/10/16	rogid:1xgNdDNjWbnuljME8jaSCCj1Bcw9606	rogid:FhTSp74g5BnJShAOSoqX/UwQuBM9606	intact-crc:1187E5F2E76EDD65|rigid:LmukdRAEDdojQEecQDjoJEd+f+4	false	glutathione s tranferase tag:?-?|sufficient binding region:56-267	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7L0Q8	uniprotkb:Q13153-2	intact:EBI-1638043|uniprotkb:B1AKN1|uniprotkb:Q59FE9|uniprotkb:Q8TDQ2|ensembl:ENSP00000355652|ensembl:ENSP00000494673	intact:EBI-1019502|ensembl:ENSP00000278568	psi-mi:rhou_human(display_long)|uniprotkb:RHOU(gene name)|psi-mi:RHOU(display_short)|uniprotkb:ARHU(gene name synonym)|uniprotkb:CDC42L1(gene name synonym)|uniprotkb:G28K(gene name synonym)|uniprotkb:WRCH1(gene name synonym)|uniprotkb:SB128(orf name)|uniprotkb:Wnt-1 responsive Cdc42 homolog 1(gene name synonym)|uniprotkb:Ryu GTPase(gene name synonym)|uniprotkb:CDC42-like GTPase 1(gene name synonym)|uniprotkb:Rho GTPase-like protein ARHU(gene name synonym)|uniprotkb:GTP-binding protein-like 1(gene name synonym)	psi-mi:q13153-2(display_long)|uniprotkb:PAK1B(isoform synonym)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Aspenstrom et al. (2004)	pubmed:14521508|imex:IM-18830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6285780|imex:IM-18830-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067028.1|ensembl:ENSG00000116574(gene)|ensembl:ENST00000366691(transcript)|ensembl:ENST00000646945(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002102"(podosome)|ensembl:ENSG00000284984(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q7L0Q8|rcsb pdb:2Q3H|reactome:R-HSA-6785807|reactome:R-HSA-9013420	intact:EBI-1307(pak1_human)|uniprotkb:Q13153-2(isoform-parent)|ensembl:ENSG00000149269(gene)|ensembl:ENST00000278568(transcript)	-	-	-	figure legend:Fig 7A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/31	2014/10/16	rogid:wrOPjo6G3FraKiREmUiUqoHYuEc9606	rogid:1xgNdDNjWbnuljME8jaSCCj1Bcw9606	intact-crc:328F13F1E4CF81B0|rigid:MP/QuWYPkKPn72LGbJN4oVt+G0c	false	myc tag:?-?	sufficient binding region:56-267|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P15153	uniprotkb:Q13153-2	intact:EBI-489652|ensembl:ENSP00000249071|uniprotkb:Q9UDJ4	intact:EBI-1019502|ensembl:ENSP00000278568	psi-mi:rac2_human(display_long)|uniprotkb:p21-Rac2(gene name synonym)|uniprotkb:Small G protein(gene name synonym)|uniprotkb:GX(gene name synonym)|uniprotkb:RAC2(gene name)|psi-mi:RAC2(display_short)	psi-mi:q13153-2(display_long)|uniprotkb:PAK1B(isoform synonym)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Aspenstrom et al. (2004)	pubmed:14521508|imex:IM-18830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6285790|imex:IM-18830-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045453"(bone resorption)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060753"(regulation of mast cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P15153|rcsb pdb:1DS6|rcsb pdb:2W2T|rcsb pdb:2W2V|rcsb pdb:2W2X|reactome:R-HSA-114604|reactome:R-HSA-1222556|go:"GO:0043304"(regulation of mast cell degranulation)|ensembl:ENSG00000128340(gene)|ensembl:ENST00000249071(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010810"(regulation of cell-substrate adhesion)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0005925"(focal adhesion)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-HSA-1257604|refseq:NP_002863.1|reactome:R-HSA-2219530|reactome:R-HSA-4086400|reactome:R-HSA-5668599|reactome:R-HSA-6811558|reactome:R-HSA-9013404|dip:DIP-34291N	intact:EBI-1307(pak1_human)|uniprotkb:Q13153-2(isoform-parent)|ensembl:ENSG00000149269(gene)|ensembl:ENST00000278568(transcript)	-	-	-	figure legend:Fig 7A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/31	2014/10/16	rogid:NYkPt/WNmKM3qAhhaufLCPkc/io9606	rogid:1xgNdDNjWbnuljME8jaSCCj1Bcw9606	intact-crc:EC80C5B71CE51F5F|rigid:Xgat2cVHTKrtxkzWQbalMFEUqsk	false	myc tag:?-?	sufficient binding region:56-267|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P60763	uniprotkb:Q13153-2	intact:EBI-767084|uniprotkb:O14658|uniprotkb:Q5U0M8|ensembl:ENSP00000304283	intact:EBI-1019502|ensembl:ENSP00000278568	psi-mi:rac3_human(display_long)|uniprotkb:p21-Rac3(gene name synonym)|uniprotkb:RAC3(gene name)|psi-mi:RAC3(display_short)	psi-mi:q13153-2(display_long)|uniprotkb:PAK1B(isoform synonym)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)	psi-mi:"MI:0096"(pull down)	Aspenstrom et al. (2004)	pubmed:14521508|imex:IM-18830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6285800|imex:IM-18830-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005043.1|dip:DIP-33881N|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2C2H|rcsb pdb:2G0N|rcsb pdb:2IC5|rcsb pdb:2OV2|rcsb pdb:2QME|rcsb pdb:6TM1|reactome:R-HSA-4086400|reactome:R-HSA-9013423|ensembl:ENSG00000169750(gene)|ensembl:ENST00000306897(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0012505"(endomembrane system)|go:"GO:0014041"(regulation of neuron maturation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021894"(cerebral cortex GABAergic interneuron development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0030027"(lamellipodium)	intact:EBI-1307(pak1_human)|uniprotkb:Q13153-2(isoform-parent)|ensembl:ENSG00000149269(gene)|ensembl:ENST00000278568(transcript)	-	-	-	figure legend:Fig 7A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/31	2014/10/16	rogid:YWu9Tmqxzxu49RSwmyfhawoOUis9606	rogid:1xgNdDNjWbnuljME8jaSCCj1Bcw9606	intact-crc:6C01AB114E49EA52|rigid:Sr8QfdYzQGIbjMFwcpulLICZdIY	false	myc tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:56-267	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13153-2	uniprotkb:P17081	intact:EBI-1019502|ensembl:ENSP00000278568	intact:EBI-689202|uniprotkb:Q0VGN1|uniprotkb:Q52LS8|uniprotkb:Q53SJ1|uniprotkb:Q6NS39|uniprotkb:Q6P146|uniprotkb:Q7Z480|uniprotkb:D6W5A6|ensembl:ENSP00000238738	psi-mi:q13153-2(display_long)|uniprotkb:PAK1B(isoform synonym)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)	psi-mi:rhoq_human(display_long)|uniprotkb:Ras-like protein TC10(gene name synonym)|uniprotkb:Ras-like protein family member 7A(gene name synonym)|uniprotkb:RHOQ(gene name)|psi-mi:RHOQ(display_short)|uniprotkb:ARHQ(gene name synonym)|uniprotkb:RASL7A(gene name synonym)|uniprotkb:TC10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Aspenstrom et al. (2004)	pubmed:14521508|imex:IM-18830	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6285810|imex:IM-18830-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1307(pak1_human)|uniprotkb:Q13153-2(isoform-parent)|ensembl:ENSG00000149269(gene)|ensembl:ENST00000278568(transcript)	refseq:NP_036381.2|ensembl:ENSG00000119729(gene)|ensembl:ENST00000238738(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005522"(profilin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2ATX|reactome:R-HSA-1445148|reactome:R-HSA-5627083|reactome:R-HSA-9013406	-	-	-	figure legend:Fig 7A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/31	2014/10/16	rogid:1xgNdDNjWbnuljME8jaSCCj1Bcw9606	rogid:+7R9kNHFo4Sk46daCd13CDtKAR09606	intact-crc:81ED2162701BB765|rigid:vdKb7j3pqZOy+DcWnqaBcjXb3og	false	sufficient binding region:56-267|glutathione s tranferase tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)